DHFR |
cytosol |
GO:0005829 |
DHFR |
mitochondrion |
GO:0005739 |
DHFR |
dihydrofolate reductase activity |
GO:0004146 |
DHFR |
drug binding |
GO:0008144 |
DHFR |
folic acid binding |
GO:0005542 |
DHFR |
methotrexate binding |
GO:0051870 |
DHFR |
mRNA binding |
GO:0003729 |
DHFR |
NADP binding |
GO:0050661 |
DHFR |
NADPH binding |
GO:0070402 |
DHFR |
sequence-specific mRNA binding |
GO:1990825 |
DHFR |
translation repressor activity, mRNA regulatory element binding |
GO:0000900 |
DHFR |
axon regeneration |
GO:0031103 |
DHFR |
dihydrofolate metabolic process |
GO:0046452 |
DHFR |
folic acid metabolic process |
GO:0046655 |
DHFR |
negative regulation of translation |
GO:0017148 |
DHFR |
one-carbon metabolic process |
GO:0006730 |
DHFR |
oxidation-reduction process |
GO:0055114 |
DHFR |
positive regulation of nitric-oxide synthase activity |
GO:0051000 |
DHFR |
regulation of removal of superoxide radicals |
GO:2000121 |
DHFR |
regulation of transcription involved in G1/S transition of mitotic cell cycle |
GO:0000083 |
DHFR |
response to methotrexate |
GO:0031427 |
DHFR |
tetrahydrobiopterin biosynthetic process |
GO:0006729 |
DHFR |
tetrahydrofolate biosynthetic process |
GO:0046654 |
DHFR |
tetrahydrofolate metabolic process |
GO:0046653 |