| PSEN1 |
aggresome |
GO:0016235 |
| PSEN1 |
apical plasma membrane |
GO:0016324 |
| PSEN1 |
axon |
GO:0030424 |
| PSEN1 |
azurophil granule membrane |
GO:0035577 |
| PSEN1 |
cell cortex |
GO:0005938 |
| PSEN1 |
cell junction |
GO:0030054 |
| PSEN1 |
cell surface |
GO:0009986 |
| PSEN1 |
centrosome |
GO:0005813 |
| PSEN1 |
ciliary rootlet |
GO:0035253 |
| PSEN1 |
dendritic shaft |
GO:0043198 |
| PSEN1 |
early endosome membrane |
GO:0031901 |
| PSEN1 |
endoplasmic reticulum |
GO:0005783 |
| PSEN1 |
endoplasmic reticulum membrane |
GO:0005789 |
| PSEN1 |
gamma-secretase complex |
GO:0070765 |
| PSEN1 |
Golgi apparatus |
GO:0005794 |
| PSEN1 |
Golgi membrane |
GO:0000139 |
| PSEN1 |
growth cone |
GO:0030426 |
| PSEN1 |
integral component of membrane |
GO:0016021 |
| PSEN1 |
integral component of plasma membrane |
GO:0005887 |
| PSEN1 |
integral component of presynaptic membrane |
GO:0099056 |
| PSEN1 |
kinetochore |
GO:0000776 |
| PSEN1 |
lysosomal membrane |
GO:0005765 |
| PSEN1 |
membrane |
GO:0016020 |
| PSEN1 |
membrane raft |
GO:0045121 |
| PSEN1 |
mitochondrial inner membrane |
GO:0005743 |
| PSEN1 |
mitochondrion |
GO:0005739 |
| PSEN1 |
neuromuscular junction |
GO:0031594 |
| PSEN1 |
neuron projection |
GO:0043005 |
| PSEN1 |
neuronal cell body |
GO:0043025 |
| PSEN1 |
nuclear membrane |
GO:0031965 |
| PSEN1 |
nuclear outer membrane |
GO:0005640 |
| PSEN1 |
nucleoplasm |
GO:0005654 |
| PSEN1 |
nucleus |
GO:0005634 |
| PSEN1 |
perinuclear region of cytoplasm |
GO:0048471 |
| PSEN1 |
plasma membrane |
GO:0005886 |
| PSEN1 |
protein-containing complex |
GO:0032991 |
| PSEN1 |
rough endoplasmic reticulum |
GO:0005791 |
| PSEN1 |
sarcolemma |
GO:0042383 |
| PSEN1 |
smooth endoplasmic reticulum |
GO:0005790 |
| PSEN1 |
synaptic vesicle |
GO:0008021 |
| PSEN1 |
Z disc |
GO:0030018 |
| PSEN1 |
aspartic endopeptidase activity, intramembrane cleaving |
GO:0042500 |
| PSEN1 |
aspartic-type endopeptidase activity |
GO:0004190 |
| PSEN1 |
ATPase binding |
GO:0051117 |
| PSEN1 |
beta-catenin binding |
GO:0008013 |
| PSEN1 |
cadherin binding |
GO:0045296 |
| PSEN1 |
calcium channel activity |
GO:0005262 |
| PSEN1 |
endopeptidase activity |
GO:0004175 |
| PSEN1 |
growth factor receptor binding |
GO:0070851 |
| PSEN1 |
PDZ domain binding |
GO:0030165 |
| PSEN1 |
activation of MAPKK activity |
GO:0000186 |
| PSEN1 |
amyloid precursor protein catabolic process |
GO:0042987 |
| PSEN1 |
amyloid precursor protein metabolic process |
GO:0042982 |
| PSEN1 |
amyloid-beta formation |
GO:0034205 |
| PSEN1 |
amyloid-beta metabolic process |
GO:0050435 |
| PSEN1 |
astrocyte activation |
GO:0048143 |
| PSEN1 |
astrocyte activation involved in immune response |
GO:0002265 |
| PSEN1 |
autophagosome assembly |
GO:0000045 |
| PSEN1 |
blood vessel development |
GO:0001568 |
| PSEN1 |
brain morphogenesis |
GO:0048854 |
| PSEN1 |
Cajal-Retzius cell differentiation |
GO:0021870 |
| PSEN1 |
calcium ion transport |
GO:0006816 |
| PSEN1 |
cell fate specification |
GO:0001708 |
| PSEN1 |
cell-cell adhesion |
GO:0098609 |
| PSEN1 |
cellular response to amyloid-beta |
GO:1904646 |
| PSEN1 |
cellular response to DNA damage stimulus |
GO:0006974 |
| PSEN1 |
cerebellum development |
GO:0021549 |
| PSEN1 |
cerebral cortex cell migration |
GO:0021795 |
| PSEN1 |
choline transport |
GO:0015871 |
| PSEN1 |
dorsal/ventral neural tube patterning |
GO:0021904 |
| PSEN1 |
embryonic limb morphogenesis |
GO:0030326 |
| PSEN1 |
endoplasmic reticulum calcium ion homeostasis |
GO:0032469 |
| PSEN1 |
ephrin receptor signaling pathway |
GO:0048013 |
| PSEN1 |
epithelial cell proliferation |
GO:0050673 |
| PSEN1 |
heart looping |
GO:0001947 |
| PSEN1 |
hematopoietic progenitor cell differentiation |
GO:0002244 |
| PSEN1 |
intracellular signal transduction |
GO:0035556 |
| PSEN1 |
learning or memory |
GO:0007611 |
| PSEN1 |
membrane protein ectodomain proteolysis |
GO:0006509 |
| PSEN1 |
membrane protein intracellular domain proteolysis |
GO:0031293 |
| PSEN1 |
memory |
GO:0007613 |
| PSEN1 |
mitochondrial transport |
GO:0006839 |
| PSEN1 |
modulation of age-related behavioral decline |
GO:0090647 |
| PSEN1 |
myeloid dendritic cell differentiation |
GO:0043011 |
| PSEN1 |
negative regulation of apoptotic process |
GO:0043066 |
| PSEN1 |
negative regulation of apoptotic signaling pathway |
GO:2001234 |
| PSEN1 |
negative regulation of axonogenesis |
GO:0050771 |
| PSEN1 |
negative regulation of core promoter binding |
GO:1904797 |
| PSEN1 |
negative regulation of epidermal growth factor-activated receptor activity |
GO:0007175 |
| PSEN1 |
negative regulation of gene expression |
GO:0010629 |
| PSEN1 |
negative regulation of neuron apoptotic process |
GO:0043524 |
| PSEN1 |
negative regulation of transcription by RNA polymerase II |
GO:0000122 |
| PSEN1 |
negative regulation of ubiquitin-dependent protein catabolic process |
GO:2000059 |
| PSEN1 |
negative regulation of ubiquitin-protein transferase activity |
GO:0051444 |
| PSEN1 |
neural retina development |
GO:0003407 |
| PSEN1 |
neuron apoptotic process |
GO:0051402 |
| PSEN1 |
neuron development |
GO:0048666 |
| PSEN1 |
neuron migration |
GO:0001764 |
| PSEN1 |
neuron projection maintenance |
GO:1990535 |
| PSEN1 |
neutrophil degranulation |
GO:0043312 |
| PSEN1 |
Notch receptor processing |
GO:0007220 |
| PSEN1 |
Notch receptor processing, ligand-dependent |
GO:0035333 |
| PSEN1 |
positive regulation of amyloid fibril formation |
GO:1905908 |
| PSEN1 |
positive regulation of apoptotic process |
GO:0043065 |
| PSEN1 |
positive regulation of catalytic activity |
GO:0043085 |
| PSEN1 |
positive regulation of coagulation |
GO:0050820 |
| PSEN1 |
positive regulation of dendritic spine development |
GO:0060999 |
| PSEN1 |
positive regulation of gene expression |
GO:0010628 |
| PSEN1 |
positive regulation of glycolytic process |
GO:0045821 |
| PSEN1 |
positive regulation of L-glutamate import across plasma membrane |
GO:0002038 |
| PSEN1 |
positive regulation of phosphorylation |
GO:0042327 |
| PSEN1 |
positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
GO:0032436 |
| PSEN1 |
positive regulation of protein binding |
GO:0032092 |
| PSEN1 |
positive regulation of protein import into nucleus |
GO:0042307 |
| PSEN1 |
positive regulation of receptor recycling |
GO:0001921 |
| PSEN1 |
positive regulation of transcription, DNA-templated |
GO:0045893 |
| PSEN1 |
positive regulation of tumor necrosis factor biosynthetic process |
GO:0042535 |
| PSEN1 |
post-embryonic development |
GO:0009791 |
| PSEN1 |
protein glycosylation |
GO:0006486 |
| PSEN1 |
protein processing |
GO:0016485 |
| PSEN1 |
protein transport |
GO:0015031 |
| PSEN1 |
regulation of canonical Wnt signaling pathway |
GO:0060828 |
| PSEN1 |
regulation of gene expression |
GO:0010468 |
| PSEN1 |
regulation of neuron projection development |
GO:0010975 |
| PSEN1 |
regulation of phosphorylation |
GO:0042325 |
| PSEN1 |
regulation of resting membrane potential |
GO:0060075 |
| PSEN1 |
regulation of synaptic plasticity |
GO:0048167 |
| PSEN1 |
regulation of synaptic transmission, glutamatergic |
GO:0051966 |
| PSEN1 |
response to oxidative stress |
GO:0006979 |
| PSEN1 |
skeletal system morphogenesis |
GO:0048705 |
| PSEN1 |
skin morphogenesis |
GO:0043589 |
| PSEN1 |
smooth endoplasmic reticulum calcium ion homeostasis |
GO:0051563 |
| PSEN1 |
somitogenesis |
GO:0001756 |
| PSEN1 |
synapse organization |
GO:0050808 |
| PSEN1 |
synaptic vesicle targeting |
GO:0016080 |
| PSEN1 |
T cell activation involved in immune response |
GO:0002286 |
| PSEN1 |
T cell receptor signaling pathway |
GO:0050852 |
| PSEN1 |
thymus development |
GO:0048538 |