Gene Pathway Pathway source Gene number Edge number
CHEK2 ATM pathway pid 34 262
CHEK2 FOXM1 transcription factor network pid 43 294
CHEK2 G2/M DNA damage checkpoint reactome 84 2251
CHEK2 p53 pathway pid 59 356
CHEK2 PLK3 signaling events pid 6 12
CHEK2 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks reactome 75 2122
CHEK2 Regulation of TP53 Activity through Methylation reactome 19 77
CHEK2 Regulation of TP53 Activity through Phosphorylation reactome 89 1144
CHEK2 Regulation of TP53 Degradation reactome 35 257
CHEK2 Stabilization of p53 reactome 9 35
CHEK2 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A reactome 52 1146
CHEK2 Cell cycle kegg 124 2334
CHEK2 Cell cycle - yeast kegg 66 476
CHEK2 p53 signaling pathway kegg 66 297
CHEK2 Hs_DNA_Damage_Response_WP707_82937 wikipathways 28 166
CHEK2 Hs_miRNA_Regulation_of_DNA_Damage_Response_WP1530_84694 wikipathways 28 154
CHEK2 Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941 wikipathways 122 1333
CHEK2 Hs_Integrated_Cancer_Pathway_WP1971_82939 wikipathways 33 206
CHEK2 Hs_ATM_Signaling_Pathway_WP2516_90247 wikipathways 32 187
CHEK2 Hs_DNA_IR-Double_Strand_Breaks_(DSBs)_and_cellular_response_via_ATM_WP3959_91367 wikipathways 50 393