Gene Pathway Pathway source Gene number Edge number
HDAC1 Activation of rRNA Expression by ERCC6 (CSB) and EHMT2 (G9a) reactome 74 2448
HDAC1 AndrogenReceptor netpath 167 2267
HDAC1 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants reactome 57 500
HDAC1 Constitutive Signaling by NOTCH1 PEST Domain Mutants reactome 57 500
HDAC1 Deactivation of the beta-catenin transactivating complex reactome 42 236
HDAC1 Downregulation of SMAD2/3:SMAD4 transcriptional activity reactome 23 145
HDAC1 E2F transcription factor network pid 77 897
HDAC1 EGFR1 netpath 475 10010
HDAC1 Factors involved in megakaryocyte development and platelet production reactome 111 689
HDAC1 Formation of the beta-catenin:TCF transactivating complex reactome 88 3060
HDAC1 G0 and Early G1 reactome 25 194
HDAC1 Glucocorticoid receptor regulatory network pid 85 876
HDAC1 HDACs deacetylate histones reactome 94 3780
HDAC1 Hedgehog signaling events mediated by Gli proteins pid 49 297
HDAC1 IL3-mediated signaling events pid 27 155
HDAC1 IL6 netpath 85 1335
HDAC1 Negative regulation of (transcription by R-smad:smad4) in TGF beta super family signaling pathway ( TGF-beta_super_family_signaling_pathway(canonical) ) inoh 21 184
HDAC1 NoRC negatively regulates rRNA expression reactome 104 4095
HDAC1 Notch-mediated HES/HEY network pid 48 337
HDAC1 Notch netpath 76 661
HDAC1 Notch signaling pathway pid 58 321
HDAC1 NOTCH1 Intracellular Domain Regulates Transcription reactome 47 463
HDAC1 p53 pathway panther 39 274
HDAC1 p75NTR negatively regulates cell cycle via SC1 reactome 6 10
HDAC1 Presenilin action in Notch and Wnt signaling pid 46 287
HDAC1 Regulation of Androgen receptor activity pid 54 338
HDAC1 Regulation of nuclear beta catenin signaling and target gene transcription pid 80 611
HDAC1 Regulation of nuclear SMAD2/3 signaling pid 82 1072
HDAC1 Regulation of retinoblastoma protein pid 67 718
HDAC1 Regulation of Telomerase pid 70 708
HDAC1 Regulation of TP53 Activity through Acetylation reactome 23 208
HDAC1 Repression of WNT target genes reactome 14 68
HDAC1 Retinoic acid receptors-mediated signaling pid 30 235
HDAC1 RNA Polymerase I Transcription Initiation reactome 47 743
HDAC1 Signaling events mediated by HDAC Class I pid 89 1618
HDAC1 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription reactome 32 197
HDAC1 Sumoylation by RanBP2 regulates transcriptional repression pid 15 84
HDAC1 TGF_beta_Receptor netpath 220 4100
HDAC1 TNFalpha netpath 274 5236
HDAC1 TWEAK netpath 35 280
HDAC1 Validated nuclear estrogen receptor alpha network pid 65 386
HDAC1 Validated targets of C-MYC transcriptional repression pid 63 385
HDAC1 Wnt signaling pathway panther 250 3827
HDAC1 Cell cycle kegg 124 2334
HDAC1 Notch signaling pathway kegg 44 313
HDAC1 Huntingtons disease kegg 182 1941
HDAC1 Pathways in cancer kegg 321 8293
HDAC1 Chronic myeloid leukemia kegg 69 881
HDAC1 Hs_Apoptosis-related_network_due_to_altered_Notch3_in_ovarian_cancer_WP2864_79278 wikipathways 51 206
HDAC1 Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941 wikipathways 122 1333
HDAC1 Hs_Energy_Metabolism_WP1541_91584 wikipathways 13 34
HDAC1 Hs_IL-6_signaling_pathway_WP364_89832 wikipathways 26 174
HDAC1 Hs_Androgen_receptor_signaling_pathway_WP138_79958 wikipathways 27 107
HDAC1 Hs_Notch_Signaling_Pathway_WP61_78592 wikipathways 16 52