Gene Pathway Pathway source Gene number Edge number
IRAK1 activated TAK1 mediates p38 MAPK activation reactome 17 99
IRAK1 AKT(PKB)-Bad signaling ( EPO signaling pathway(JAK2 STAT1 STAT3 STAT5) ) inoh 173 2371
IRAK1 AKT(PKB)-Bad signaling ( IL-7 signaling(JAK1 JAK3 STAT5) ) inoh 173 2371
IRAK1 Drosophila Toll-like receptor signaling ( Drosophila Toll-like receptor signaling ) inoh 236 3833
IRAK1 Endogenous TLR signaling pid 26 158
IRAK1 IL-1 signaling pathway (through p38 cascade) ( IL-1 signaling pathway (through p38 cascade) ) inoh 14 65
IRAK1 IL-1_signaling(through_IKK-NFkB_cascade)(canonical) ( IL-1 signaling pathway (through NF-kappaB) ) inoh 15 75
IRAK1 IL-1_signaling(through_JNK_cascade)(canonical) ( IL-1 signaling pathway (through JNK cascade) ) inoh 14 65
IRAK1 IL1-mediated signaling events pid 34 272
IRAK1 IL1 netpath 69 701
IRAK1 Interleukin-1 signaling reactome 31 234
IRAK1 IRAK1 recruits IKK complex reactome 10 34
IRAK1 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation reactome 10 34
IRAK1 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 reactome 16 100
IRAK1 MyD88 cascade initiated on plasma membrane reactome 9 26
IRAK1 MyD88 dependent cascade initiated on endosome reactome 8 26
IRAK1 MyD88:Mal cascade initiated on plasma membrane reactome 19 126
IRAK1 NF-kB is activated and signals survival reactome 13 61
IRAK1 NOD1/2 Signaling Pathway reactome 31 245
IRAK1 p75(NTR)-mediated signaling pid 74 564
IRAK1 p75NTR recruits signalling complexes reactome 13 53
IRAK1 Positive regulation of (Transcription of SOCS by STAT dimer) in JAK STAT pathway ( JAK-STAT pathway and regulation pathway Diagram ) inoh 178 3507
IRAK1 TAK1 activates NFkB by phosphorylation and activation of IKKs complex reactome 26 173
IRAK1 Toll-like receptor signaling pathway (p38 cascade) ( Toll-like receptor signaling pathway (p38 cascade) ) inoh 14 70
IRAK1 Toll-like receptor signaling pathway (through ECSIT, MEKK1, MKKs, JNK cascade) ( Toll-like receptor signaling pathway (through ECSIT, MEKK1, MKKs, JNK cascade) ) inoh 15 62
IRAK1 Toll-like receptor signaling pathway (through ECSIT, MEKK1, MKKs, p38 cascade) ( Toll-like receptor signaling pathway (through ECSIT, MEKK1, MKKs, p38 cascade) ) inoh 14 58
IRAK1 Toll-like receptor signaling pathway (through JNK cascade)(Canonical) ( Toll-like receptor signaling pathway (through JNK cascade) ) inoh 14 70
IRAK1 Toll-like receptor signaling pathway (through LPS, TLR4, MyD88, IRAK, TAK1 and IKK-NF-kappaB cascade)(Canonical) ( Toll-like receptor signaling pathway (trough NF-kappaB) ) inoh 19 103
IRAK1 Toll receptor signaling pathway panther 44 352
IRAK1 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation reactome 10 31
IRAK1 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling reactome 11 46
IRAK1 VEGF signaling pathway ( VEGF signaling pathway ) inoh 183 2778
IRAK1 Apoptosis kegg 88 932
IRAK1 Toll-like receptor signaling pathway kegg 100 1158
IRAK1 Neurotrophin signaling pathway kegg 126 2153
IRAK1 Leishmaniasis kegg 71 594
IRAK1 Chagas disease kegg 103 1158
IRAK1 Toxoplasmosis kegg 131 1443
IRAK1 Hs_Structural_Pathway_of_Interleukin_1_(IL-1)_WP2637_87707 wikipathways 34 195
IRAK1 Hs_Regulation_of_toll-like_receptor_signaling_pathway_WP1449_81172 wikipathways 47 253
IRAK1 Hs_Toll-like_Receptor_Signaling_Pathway_WP75_83867 wikipathways 17 68
IRAK1 Hs_IL-1_signaling_pathway_WP195_89932 wikipathways 34 225