Gene Pathway Pathway source Gene number Edge number
MDM2 AKT phosphorylates targets in the cytosol reactome 13 42
MDM2 AndrogenReceptor netpath 167 2267
MDM2 ATM pathway pid 34 262
MDM2 ATR signaling pathway pid 39 404
MDM2 Aurora A signaling pid 33 119
MDM2 Constitutive Signaling by AKT1 E17K in Cancer reactome 25 137
MDM2 Direct p53 effectors pid 141 972
MDM2 ErbB4 signaling events pid 35 223
MDM2 FSH netpath 44 301
MDM2 Glucocorticoid receptor regulatory network pid 85 876
MDM2 Insulin/IGF pathway-protein kinase B signaling cascade panther 22 94
MDM2 Oncogene Induced Senescence reactome 30 146
MDM2 Oxidative Stress Induced Senescence reactome 120 3580
MDM2 p53 pathway panther 39 274
MDM2 p53 pathway pid 59 356
MDM2 P53 pathway feedback loops 1 panther 6 16
MDM2 p73 transcription factor network pid 80 478
MDM2 Regulation of Androgen receptor activity pid 54 338
MDM2 Regulation of retinoblastoma protein pid 67 718
MDM2 Regulation of TP53 Activity through Methylation reactome 19 77
MDM2 Regulation of TP53 Activity through Phosphorylation reactome 89 1144
MDM2 Regulation of TP53 Degradation reactome 35 257
MDM2 Stabilization of p53 reactome 9 35
MDM2 Sumoylation by RanBP2 regulates transcriptional repression pid 15 84
MDM2 SUMOylation of transcription factors reactome 14 57
MDM2 Trafficking of AMPA receptors reactome 17 88
MDM2 Tryptophan degradation ( Tryptophan degradation ) inoh 60 388
MDM2 Ubiquitin proteasome pathway panther 43 383
MDM2 Validated transcriptional targets of deltaNp63 isoforms pid 47 101
MDM2 Validated transcriptional targets of TAp63 isoforms pid 54 163
MDM2 Cell cycle kegg 124 2334
MDM2 p53 signaling pathway kegg 66 297
MDM2 Endocytosis kegg 201 1991
MDM2 Pathways in cancer kegg 321 8293
MDM2 Glioma kegg 65 998
MDM2 Prostate cancer kegg 85 1261
MDM2 Melanoma kegg 69 1192
MDM2 Bladder cancer kegg 38 233
MDM2 Chronic myeloid leukemia kegg 69 881
MDM2 Hs_Cell_Cycle_WP179_89516 wikipathways 33 97
MDM2 Hs_ErbB_Signaling_Pathway_WP673_91869 wikipathways 37 312
MDM2 Hs_DNA_Damage_Response_(only_ATM_dependent)_WP710_79974 wikipathways 36 219
MDM2 Hs_TP53_Network_WP1742_71700 wikipathways 10 32
MDM2 Hs_DNA_Damage_Response_WP707_82937 wikipathways 28 166
MDM2 Hs_Apoptosis_WP254_88977 wikipathways 31 127
MDM2 Hs_Senescence_and_Autophagy_in_Cancer_WP615_81193 wikipathways 62 254
MDM2 Hs_Copper_homeostasis_WP3286_89205 wikipathways 15 38
MDM2 Hs_Bladder_Cancer_WP2828_89143 wikipathways 17 74
MDM2 Hs_Signaling_Pathways_in_Glioblastoma_WP2261_89520 wikipathways 16 66
MDM2 Hs_Retinoblastoma_(RB)_in_Cancer_WP2446_87639 wikipathways 5 8
MDM2 Hs_Androgen_receptor_signaling_pathway_WP138_79958 wikipathways 27 107