Gene Pathway Pathway source Gene number Edge number
PSMC1 Activation of NF-kappaB in B cells reactome 66 1552
PSMC1 Antigen processing: Ubiquitination & Proteasome degradation reactome 260 9688
PSMC1 APC/C:Cdc20 mediated degradation of Securin reactome 66 2102
PSMC1 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 reactome 71 2321
PSMC1 Asymmetric localization of PCP proteins reactome 63 1276
PSMC1 AUF1 (hnRNP D0) binds and destabilizes mRNA reactome 54 1209
PSMC1 Autodegradation of Cdh1 by Cdh1:APC/C reactome 62 1892
PSMC1 Autodegradation of the E3 ubiquitin ligase COP1 reactome 51 1160
PSMC1 Cdc20:Phospho-APC/C mediated degradation of Cyclin A reactome 71 2480
PSMC1 CDK-mediated phosphorylation and removal of Cdc6 reactome 50 1181
PSMC1 CDT1 association with the CDC6:ORC:origin complex reactome 58 1191
PSMC1 CLEC7A (Dectin-1) signaling reactome 78 1727
PSMC1 Cross-presentation of soluble exogenous antigens (endosomes) reactome 49 946
PSMC1 Dectin-1 mediated noncanonical NF-kB signaling reactome 61 1526
PSMC1 Degradation of AXIN reactome 54 1370
PSMC1 Degradation of beta-catenin by the destruction complex reactome 67 2178
PSMC1 Degradation of DVL reactome 56 1335
PSMC1 Degradation of GLI1 by the proteasome reactome 59 1494
PSMC1 Degradation of GLI2 by the proteasome reactome 59 1505
PSMC1 Downstream TCR signaling reactome 101 1991
PSMC1 Drosophila Toll-like receptor signaling ( Drosophila Toll-like receptor signaling ) inoh 236 3833
PSMC1 ER-Phagosome pathway reactome 65 1264
PSMC1 FCERI mediated NF-kB activation reactome 88 1785
PSMC1 G2/M Checkpoints reactome 50 1193
PSMC1 GLI3 is processed to GLI3R by the proteasome reactome 59 1548
PSMC1 Hedgehog on state reactome 72 1642
PSMC1 Hedgehog ligand biogenesis reactome 59 1198
PSMC1 Hh mutants that dont undergo autocatalytic processing are degraded by ERAD reactome 55 1173
PSMC1 MAPK6/MAPK4 signaling reactome 90 1485
PSMC1 NIK-->noncanonical NF-kB signaling reactome 58 1471
PSMC1 Orc1 removal from chromatin reactome 70 1618
PSMC1 Regulation of activated PAK-2p34 by proteasome mediated degradation reactome 49 1133
PSMC1 Regulation of ornithine decarboxylase (ODC) reactome 50 1088
PSMC1 Regulation of RAS by GAPs reactome 67 1453
PSMC1 SCF-beta-TrCP mediated degradation of Emi1 reactome 54 1387
PSMC1 SCF(Skp2)-mediated degradation of p27/p21 reactome 59 1486
PSMC1 Separation of Sister Chromatids reactome 163 7519
PSMC1 SnoN degradation signaling ( TGF-beta_super_family_signaling_pathway(canonical) ) inoh 38 670
PSMC1 TGF beta receptor complex degradation signaling ( TGF-beta_super_family_signaling_pathway(canonical) ) inoh 48 1067
PSMC1 TGF beta receptor I degradation signaling ( TGF-beta_super_family_signaling_pathway(canonical) ) inoh 43 870
PSMC1 The role of GTSE1 in G2/M progression after G2 checkpoint reactome 59 1330
PSMC1 TNFalpha netpath 274 5236
PSMC1 TNFR2 non-canonical NF-kB pathway reactome 63 1836
PSMC1 Ubiquitin-dependent degradation of Cyclin D1 reactome 50 1137
PSMC1 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A reactome 52 1146
PSMC1 Vif-mediated degradation of APOBEC3G reactome 53 1334
PSMC1 Vpu mediated degradation of CD4 reactome 51 1231