TcoF overview
TcoF: ACTN1
GeneID: 150709
Name: Alpha-actinin-1
Ensembl: ENSG00000072110
Species: Human
Class: NA
Family: Actin
Disease: 3
Go term: 36
Pathway: 18
Hallmark: 2
Super Enhancer:

chr14:69468239-69527417 chr14:69382201-69447121 chr14:69393725-69419363 chr14:69430603-69440146 chr14:69385636-69447343 chr14:69388006-69447384 chr14:69427880-69450207 chr14:69388048-69447312 chr14:69393935-69447327 chr14:69387650-69447276 chr14:69402410-69420314 chr14:69443280-69447425 chr14:69402563-69425662 chr14:69442837-69446554 chr14:69402391-69410201 chr14:69388895-69447319 chr14:69394566-69447398 chr14:69394741-69447211 chr14:69394492-69446946 chr14:69402131-69446860 chr14:69402286-69447246 chr14:69430465-69447457 chr14:69402128-69426413 chr14:69402221-69423414 chr14:69403269-69449383 chr14:69387535-69420660 chr14:69379937-69446461 chr14:69402275-69449279 chr14:69400072-69447273 chr14:69350480-69449333 chr14:69394422-69447169 chr14:69405982-69445588 chr14:69364187-69447655 chr14:69404634-69450525 chr14:69406149-69422327 chr14:69400204-69420472 chr14:69404734-69448930 chr14:69394759-69450200 chr14:69344555-69450462 chr14:69351043-69448345 chr14:69344648-69450204 chr14:69342717-69450284 chr14:69344826-69447752 chr14:69343022-69447842 chr14:69343616-69448574 chr14:69391137-69447420 chr14:69374125-69447681 chr14:69378134-69450242 chr14:69350515-69450177 chr14:69344270-69450277 chr14:69361992-69447298 chr14:69378329-69447656 chr14:69345890-69450687 chr14:69402208-69447366 chr14:69344411-69448098 chr14:69351125-69447615 chr14:69345840-69447617 chr14:69403255-69456440 chr14:69443045-69447306 chr14:69394638-69446554 chr14:69405381-69444695 chr14:69394986-69446822 chr14:69401998-69449495 chr14:69400156-69447494 chr14:69378544-69465191 chr14:69378575-69423059 chr14:69442243-69447471 chr14:69378515-69455759 chr14:69378491-69456178 chr14:69402266-69410381 chr14:69394391-69423058 chr14:69388207-69447456 chr14:69402443-69446551 chr14:69388696-69450220 chr14:69390636-69455545 chr14:69388527-69447547 chr14:69403875-69447242 chr14:69398958-69447322 chr14:69404009-69420445 chr14:69393067-69446920 chr14:69441114-69450220 chr14:69404561-69426250 chr14:69441989-69450111 chr14:69404712-69420082 chr14:69406118-69419897 chr14:69441608-69449348 chr14:69404403-69426047 chr14:69441746-69449921 chr14:69404874-69420104 chr14:69350930-69378347 chr14:69405491-69426276 chr14:69442164-69450079 chr14:69399065-69446566 chr14:69390705-69447248 chr14:69393807-69446594 chr14:69393603-69446763 chr14:69392853-69446299 chr14:69364043-69446161 chr14:69435339-69450525 chr14:69442219-69449371 chr14:69376154-69450594 chr14:69441062-69450402 chr14:69405150-69449402 chr14:69394299-69456307 chr14:69394299-69456307 chr14:69393947-69465507 chr14:69394499-69405881 chr14:69389849-69447448 chr14:69389849-69447448 chr14:69348087-69455661 chr14:69328194-69456208 chr14:69397944-69455688 chr14:69399416-69454997 chr14:69402282-69419050 chr14:69405058-69435468 chr14:69388140-69448869 chr14:69406251-69445384 chr14:69388201-69423041 chr14:69410445-69431135 chr14:69327626-69387671 chr14:69405578-69443785 chr14:69442640-69450000 chr14:69442765-69448307 chr14:69404172-69447569 chr14:69402825-69447107 chr14:69404299-69455509 chr14:69403953-69447635 chr14:69404098-69450466 chr14:69432736-69447481 chr14:69403245-69447223 chr14:69401522-69447131 chr14:69404141-69446902 chr14:69359420-69450340 chr14:69405512-69426538 chr14:69388475-69426397 chr14:69441260-69450307 chr14:69440321-69450538 chr14:69388178-69424231 chr14:69388294-69450142 chr14:69402170-69419675 chr14:69402152-69429874 chr14:69439280-69450324 chr14:69433318-69448607 chr14:69442730-69447586 chr14:69378366-69447863 chr14:69403772-69426028 chr14:69388202-69447382 chr14:69388091-69447291 chr14:69403315-69446953 chr14:69401086-69455838 chr14:69403997-69446938 chr14:69402649-69426638 chr14:69402545-69447209 chr14:69402705-69422544 chr14:69378403-69447216 chr14:69377626-69447343 chr14:69377465-69448433 chr14:69403877-69446111 chr14:69389033-69426503 chr14:69403967-69455749 chr14:69390545-69450277 chr14:69389816-69447119 chr14:69388715-69423501 chr14:69387145-69423109 chr14:69421681-69456218 chr14:69378578-69407428 chr14:69388466-69447144 chr14:69404114-69447465 chr14:69408176-69448924 chr14:69404123-69447838 chr14:69401984-69423025 chr14:69366128-69389549 chr14:69382756-69447655 chr14:69378460-69447381 chr14:69377704-69447425 chr14:69441161-69447609 chr14:69328278-69455735 chr14:69388189-69447557 chr14:69404124-69447152 chr14:69404115-69447194 chr14:69404638-69447089 chr14:69409525-69437746 chr14:69405399-69444487 chr14:69404392-69445594 chr14:69403199-69447078 chr14:69402406-69428997 chr14:69402196-69420581 chr14:69402295-69422909 chr14:69402301-69420508 chr14:69401946-69423381 chr14:69402086-69420686 chr14:69401432-69420639 chr14:69402418-69420635 chr14:69402085-69423081 chr14:69402023-69420728 chr14:69402216-69422934 chr14:69401992-69420565 chr14:69504860-69553661 chr14:69503447-69518352 chr14:69501249-69562087 chr14:69500925-69523000 chr14:69504805-69547398 chr14:69504508-69528399 chr14:69500659-69564222 chr14:69500542-69564369 chr14:69500688-69523291 chr14:69503468-69524973 chr14:69503802-69520054 chr14:69508357-69549012 chr14:69508597-69517840 chr14:69508477-69517895 chr14:69500703-69561637 chr14:69500674-69536724 chr14:69508789-69554765 chr14:69500598-69556536 chr14:69503398-69562134 chr14:69503124-69547935 chr14:69500847-69561857 chr14:69501171-69561754

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Enhancer:

chr14:69010260-69012530 chr14:69059080-69061200 chr14:69099720-69102220 chr14:69120690-69123140 chr14:69168350-69170770 chr14:69257210-69259600 chr14:69279760-69282190 chr14:69413850-69415170 chr14:69415260-69417250 chr14:69417780-69418180 chr14:68910660-68913110 chr14:69418780-69419990 chr14:69351030-69351490 chr14:69351600-69352140 chr14:69359000-69360370 chr14:69376760-69378870 chr14:68928600-68929180 chr14:68929390-68929850 chr14:69046360-69048340 chr14:69159490-69159870 chr14:69353870-69355710 chr14:69355790-69356290 chr14:68992220-68994620 chr14:69041170-69042520 chr14:69346830-69347360 chr14:69357000-69358760 chr14:68850960-68852400 chr14:68859230-68860100 chr14:68866530-68867390 chr14:68867730-68868470 chr14:68868580-68869880 chr14:68907490-68907990 chr14:68934970-68936960 chr14:68991090-68991830 chr14:69001710-69003370 chr14:69007630-69008690 chr14:69031270-69033250 chr14:69077690-69079960 chr14:69098340-69099630 chr14:69124550-69126990 chr14:69127200-69127900 chr14:69133950-69134850 chr14:69135650-69137470 chr14:69228930-69231020 chr14:69275470-69277210 chr14:69421030-69423170 chr14:69430790-69432930 chr14:69435860-69437940 chr14:69470940-69473310 chr14:69480260-69482090 chr14:69508860-69511060 chr14:69511440-69512980 chr14:69514140-69514330 chr14:69525680-69527770 chr14:69534890-69537050 chr14:69559900-69562020 chr14:69571550-69573040 chr14:69603540-69603980 chr14:69604210-69606100 chr14:69658760-69660900 chr14:69734260-69736670 chr14:69821190-69823350 chr14:70009320-70011750 chr14:70059490-70060930 chr14:70095220-70097410 chr14:70097520-70098010 chr14:69433100-69435400 chr14:69515890-69517630 chr14:69532500-69534870 chr14:69073260-69075660 chr14:69598530-69600970 chr14:68845960-68848280 chr14:68857940-68858790 chr14:68988600-68990440 chr14:69062740-69064070 chr14:69220380-69221690 chr14:69388270-69390330 chr14:69390770-69392020 chr14:69474370-69476000 chr14:69476830-69477850 chr14:69478980-69479940 chr14:69515260-69515740 chr14:69540980-69541830 chr14:69727180-69729670 chr14:69788370-69788860 chr14:69967660-69968450 chr14:70006680-70008010 chr14:69500900-69502910 chr14:69729760-69730910 chr14:69282200-69284570 chr14:69364980-69366770 chr14:68937460-68939360 chr14:68939390-68940310 chr14:69067850-69068160 chr14:69194330-69196080 chr14:69196140-69198600 chr14:69215030-69216090 chr14:69216200-69217180 chr14:69285000-69285670 chr14:68893000-68895320 chr14:69320160-69322580 chr14:69376110-69376670 chr14:69685240-69685650 chr14:69177270-69177490 chr14:69177580-69179270 chr14:69179490-69180250 chr14:69438200-69438690 chr14:69241220-69243460 chr14:69324250-69325130 chr14:69339700-69340630 chr14:69367240-69367820 chr14:69842640-69844190 chr14:70019910-70021450 chr14:68833140-68833980 chr14:69410100-69410950 chr14:68809960-68811200 chr14:68852500-68854800 chr14:68887030-68888280 chr14:69692570-69694130 chr14:70027440-70029130 chr14:70040370-70041250 chr14:69452520-69454060 chr14:69529230-69531280 chr14:69699910-69701410 chr14:69349770-69350880 chr14:69400480-69400760 chr14:69400890-69401340 chr14:68944810-68947250 chr14:68834880-68837360 chr14:69005030-69007070 chr14:69563520-69564060

--
Promoter:

chr14:69340860-69446157

False
 ChIP-seq based regulatory details of ACTN1
select * from encode where Experiment_target='ACTN1'
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
 Downstream target genes of ACTN1
 Protein-protein interaction of ACTN1
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
ACTN1 XRCC4 Two-hybrid 16189514 9606 9606 BIOGRID
ACTN1 MAGEA11 Two-hybrid 16189514 9606 9606 BIOGRID
ACTN1 MYOZ1 Two-hybrid 16189514 9606 9606 BIOGRID
ACTN1 SSX2IP Reconstituted Complex 12446711 9606 9606 BIOGRID
ACTN1 PKN1 Affinity Capture-Western 11802708 9606 9606 BIOGRID
ACTN1 MYOT Affinity Capture-Western 12499399 9606 9606 BIOGRID
ACTN1 TTN Reconstituted Complex 11305911 9606 9606 BIOGRID
ACTN1 ACTN1 Co-crystal Structure 11470434 9606 9606 BIOGRID
ACTN1 PYGB Reconstituted Complex 12211109 9606 9606 BIOGRID
ACTN1 ZYX Two-hybrid 11423549 9606 9606 BIOGRID
ACTN1 ZYX Reconstituted Complex 11423549 9606 9606 BIOGRID
ACTN1 PDLIM1 Two-hybrid 11110697 9606 9606 BIOGRID
ACTN1 PDLIM1 Affinity Capture-Western 11110697 9606 9606 BIOGRID
ACTN1 CDK5R2 Two-hybrid 12223541 9606 9606 BIOGRID
ACTN1 CDK5R2 Reconstituted Complex 12223541 9606 9606 BIOGRID
ACTN1 CTNNA1 Affinity Capture-Western 7790378 9606 9606 BIOGRID
ACTN1 TUBA1A FRET 18341635 9606 9606 BIOGRID
ACTN1 TUBA1A Affinity Capture-Western 18341635 9606 9606 BIOGRID
ACTN1 DAG1 FRET 18341635 9606 9606 BIOGRID
ACTN1 DAG1 Affinity Capture-Western 18341635 9606 9606 BIOGRID
ACTN1 SORBS2 Affinity Capture-Western 16125169 9606 9606 BIOGRID
ACTN1 SORBS2 Two-hybrid 16125169 9606 9606 BIOGRID
ACTN1 SORBS2 Reconstituted Complex 16125169 9606 9606 BIOGRID
ACTN1 EZR Co-fractionation 22939629 9606 9606 BIOGRID
ACTN1 ACTN4 Co-fractionation 22939629 9606 9606 BIOGRID
ACTN1 ACTN2 Co-fractionation 22939629 9606 9606 BIOGRID
ACTN1 CALD1 Co-fractionation 22939629 9606 9606 BIOGRID
ACTN1 FAF2 Co-fractionation 22939629 9606 9606 BIOGRID
ACTN1 CSRP1 Reconstituted Complex 10926853 9606 9606 BIOGRID
ACTN1 IGSF8 Affinity Capture-Western 23463506 9606 9606 BIOGRID
ACTN1 CD81 Affinity Capture-Western 23463506 9606 9606 BIOGRID
ACTN1 ICAM1 Affinity Capture-Western 23463506 9606 9606 BIOGRID
ACTN1 IGSF8 Affinity Capture-MS 23463506 9606 9606 BIOGRID
ACTN1 CD81 Affinity Capture-MS 23463506 9606 9606 BIOGRID
ACTN1 ICAM1 Affinity Capture-MS 23463506 9606 9606 BIOGRID
ACTN1 RPS27 Two-hybrid 21988832 9606 9606 BIOGRID
ACTN1 NUMBL Two-hybrid 21988832 9606 9606 BIOGRID
ACTN1 GIT2 Two-hybrid 21988832 9606 9606 BIOGRID
ACTN1 GTF2H1 Two-hybrid 21988832 9606 9606 BIOGRID
ACTN1 KPNA2 Two-hybrid 21988832 9606 9606 BIOGRID
ACTN1 PIAS4 Two-hybrid 21988832 9606 9606 BIOGRID
ACTN1 PSMA1 Two-hybrid 21988832 9606 9606 BIOGRID
ACTN1 PDHX Two-hybrid 21988832 9606 9606 BIOGRID
ACTN1 SF3A3 Co-fractionation 22863883 9606 9606 BIOGRID
ACTN1 SRP19 Co-fractionation 22863883 9606 9606 BIOGRID
ACTN1 STAM2 Co-fractionation 22863883 9606 9606 BIOGRID
ACTN1 ACTN1 Two-hybrid 25416956 9606 9606 BIOGRID
ACTN1 ACTN3 Two-hybrid 25416956 9606 9606 BIOGRID
ACTN1 OAS1 Two-hybrid 25416956 9606 9606 BIOGRID
ACTN1 EPM2AIP1 Two-hybrid 25416956 9606 9606 BIOGRID
ACTN1 MYOZ2 Two-hybrid 25416956 9606 9606 BIOGRID
ACTN1 MICALL2 Two-hybrid 25416956 9606 9606 BIOGRID
ACTN1 KCTD6 Two-hybrid 25416956 9606 9606 BIOGRID
ACTN1 SPERT Two-hybrid 25416956 9606 9606 BIOGRID
ACTN1 CKB Co-fractionation 26344197 9606 9606 BIOGRID
ACTN1 CYC1 Co-fractionation 26344197 9606 9606 BIOGRID
ACTN1 ECSIT Co-fractionation 26344197 9606 9606 BIOGRID
ACTN1 KDM5C Co-fractionation 26344197 9606 9606 BIOGRID
ACTN1 TPM3 Co-fractionation 26344197 9606 9606 BIOGRID
ACTN1 CTNNA1 Co-localization 25241761 9606 9606 BIOGRID
ACTN1 CAMK2A Co-localization 25241761 9606 9606 BIOGRID
ACTN1 VDAC2 Co-fractionation 31536960 9606 9606 BIOGRID
ACTN1 SYNJ2BP Co-fractionation 31536960 9606 9606 BIOGRID
ACTN1 GRM5 Affinity Capture-Western 17311919 9606 9606 BIOGRID
ACTN1 ICAM5 Affinity Capture-Western 16820411 9606 9606 BIOGRID
ACTN1 HTT Co-localization 30768638 9606 9606 BIOGRID
ACTN1 LNX1 Two-hybrid 32296183 9606 9606 BIOGRID
ACTN1 GADD45G Two-hybrid 32296183 9606 9606 BIOGRID
ACTN1 EIF2S1 Two-hybrid 32296183 9606 9606 BIOGRID
ACTN1 TXN Two-hybrid 32296183 9606 9606 BIOGRID
ACTN1 DYNLT1 Two-hybrid 32296183 9606 9606 BIOGRID
ACTN1 C11orf57 Two-hybrid 32296183 9606 9606 BIOGRID
ACTN1 MICALL2 Two-hybrid 32296183 9606 9606 BIOGRID
ACTN1 SYNPO2L Two-hybrid 32296183 9606 9606 BIOGRID
ACTN1 MYOZ2 Two-hybrid 32296183 9606 9606 BIOGRID
ACTN1 MYOZ1 Two-hybrid 32296183 9606 9606 BIOGRID
ACTN1 EPM2AIP1 Two-hybrid 32296183 9606 9606 BIOGRID
ACTN1 C14orf119 Two-hybrid 32296183 9606 9606 BIOGRID
ACTN1 ACTN3 Two-hybrid 32296183 9606 9606 BIOGRID
ACTN1 SYNPO Proximity Label-MS 30021884 9606 9606 BIOGRID
ACTN1 Grm5 Reconstituted Complex 17311919 9606 10090 BIOGRID
ACTN1 Grm5 Co-localization 17311919 9606 10090 BIOGRID
 Annotation of ACTN1
 TCGA cancer survival map of ACTN1


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  ACTN1