TcoF overview
TcoF: BIRC5
GeneID: 29117
Name: Baculoviral IAP repeat-containing protein 5
Ensembl: ENSG00000089685
Species: Human
Class: class HC
Family: Others
Disease: 40
Go term: 45
Pathway: 17
Hallmark: 6
Super Enhancer:

chr17:76191341-76208577

Enhancer:

chr17:76210510-76210760 chr17:76266030-76266730 chr17:76289750-76291410 chr17:76462450-76462730 chr17:76462900-76463850 chr17:76071360-76073260 chr17:76164800-76166890 chr17:76501530-76502800 chr17:76557020-76557790 chr17:76563250-76565240 chr17:76135320-76136910 chr17:76169010-76170150 chr17:76085200-76087200 chr17:76120860-76120960 chr17:76121070-76121230 chr17:76121340-76121800 chr17:76167140-76167590 chr17:76167730-76167810 chr17:76171030-76171130 chr17:76446930-76447550 chr17:76120260-76120600 chr17:76133490-76133790 chr17:76142530-76142950 chr17:76191530-76193220 chr17:76117250-76117630 chr17:76117790-76118680 chr17:76198830-76200730 chr17:76133900-76134080 chr17:76044150-76044920 chr17:76054070-76055900 chr17:76249800-76251440 chr17:76118830-76120060 chr17:76157340-76159670 chr17:76171250-76171600 chr17:76260300-76262050 chr17:76114020-76115050 chr17:75879620-75880000 chr17:76116910-76117090 chr17:76258000-76259320 chr17:76266930-76267330 chr17:76493120-76494920 chr17:76134270-76134420 chr17:76188290-76190670 chr17:76210870-76212040 chr17:76134810-76135240 chr17:76151220-76152480 chr17:76154620-76157030 chr17:76237070-76239130 chr17:76470400-76471350 chr17:76000350-76001070 chr17:76074180-76075470 chr17:76506590-76507340 chr17:76523080-76525550 chr17:76567860-76568780 chr17:76568980-76570480 chr17:76221720-76222390 chr17:76554340-76556820 chr17:76446480-76446760 chr17:76622960-76623990 chr17:76676430-76677050 chr17:76704340-76705730 chr17:76834830-76836820 chr17:76626510-76628030 chr17:76104920-76105130 chr17:76112880-76113340 chr17:76113430-76113540 chr17:76113730-76113880 chr17:76200820-76200900 chr17:76200980-76201170 chr17:76392470-76394330 chr17:76395620-76396750 chr17:76472820-76475100 chr17:76489300-76490090 chr17:76624120-76626110 chr17:76795110-76795740 chr17:76832460-76834660 chr17:76848100-76849050 chr17:76018280-76019370 chr17:76026240-76027590 chr17:76324450-76326390 chr17:76326430-76327920 chr17:76330290-76332340 chr17:76361160-76363270 chr17:76379350-76381570 chr17:75806300-75808350 chr17:75939800-75941940 chr17:75829460-75831940 chr17:76296540-76298780 chr17:76533560-76535640 chr17:76536980-76539300 chr17:76552950-76554180 chr17:76700040-76701930 chr17:76704080-76704270 chr17:76710730-76713010 chr17:76770530-76771570 chr17:76772290-76773700 chr17:76796460-76797020 chr17:76445670-76446330 chr17:76451920-76454090 chr17:76481240-76481630 chr17:76653670-76655180 chr17:75832110-75833450 chr17:76194060-76196180 chr17:76499140-76501370 chr17:76870000-76870840 chr17:76218620-76219540 chr17:76506150-76506460 chr17:76527110-76528560 chr17:76562810-76563080 chr17:76814860-76816010 chr17:76204250-76204740 chr17:75486940-75488700 chr17:76235360-76235860 chr17:76402580-76402800 chr17:76667700-76670120 chr17:76596260-76596900 chr17:76318400-76319780 chr17:76394430-76395420 chr17:76396940-76398520 chr17:76420740-76421420 chr17:76424140-76424600 chr17:76425380-76425850 chr17:76481840-76482040 chr17:76487650-76488710 chr17:76656560-76658960 chr17:76665880-76666830 chr17:76860120-76860470 chr17:76871110-76873520 chr17:76790600-76792940 chr17:75919320-75921680 chr17:75930580-75931800 chr17:75931820-75932180 chr17:75944100-75946280 chr17:76388750-76389800 chr17:76512790-76514020 chr17:76083760-76084230 chr17:76572040-76573370 chr17:76098630-76099490 chr17:76490280-76490670 chr17:76490900-76491040 chr17:76491180-76491400 chr17:76302950-76304990 chr17:76305750-76305990 chr17:76336120-76337110 chr17:76340580-76343020 chr17:76761560-76763750 chr17:76764050-76764990 chr17:76765130-76766070

Promoter:

chr17:76210267-76221717

 ChIP-seq based regulatory details of BIRC5
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
 Downstream target genes of BIRC5
 Protein-protein interaction of BIRC5
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
BIRC5 AURKB Two-hybrid 11516652 9606 9606 BIOGRID
BIRC5 AURKB Reconstituted Complex 12419797 9606 9606 BIOGRID
BIRC5 AURKB Phenotypic Enhancement 12419797 9606 9606 BIOGRID
BIRC5 INCENP Reconstituted Complex 11516652 9606 9606 BIOGRID
BIRC5 AURKB Reconstituted Complex 11516652 9606 9606 BIOGRID
BIRC5 INCENP Co-localization 11516652 9606 9606 BIOGRID
BIRC5 BIRC5 Co-crystal Structure 10876248 9606 9606 BIOGRID
BIRC5 BIRC5 Co-crystal Structure 10949039 9606 9606 BIOGRID
BIRC5 CASP7 Reconstituted Complex 9850056 9606 9606 BIOGRID
BIRC5 CASP3 Reconstituted Complex 9850056 9606 9606 BIOGRID
BIRC5 CDK2 Affinity Capture-Western 11069302 9606 9606 BIOGRID
BIRC5 CASP9 Affinity Capture-Western 11069302 9606 9606 BIOGRID
BIRC5 BIRC5 Reconstituted Complex 11170436 9606 9606 BIOGRID
BIRC5 CASP7 Biochemical Activity 11170436 9606 9606 BIOGRID
BIRC5 CASP3 Biochemical Activity 11170436 9606 9606 BIOGRID
BIRC5 CASP3 Reconstituted Complex 11170436 9606 9606 BIOGRID
BIRC5 CASP7 Reconstituted Complex 11170436 9606 9606 BIOGRID
BIRC5 CDK4 Affinity Capture-Western 10713676 9606 9606 BIOGRID
BIRC5 AURKB Co-localization 19951914 9606 9606 BIOGRID
BIRC5 XIAP Affinity Capture-Western 15218035 9606 9606 BIOGRID
BIRC5 USP9X Affinity Capture-Western 16322459 9606 9606 BIOGRID
BIRC5 UFD1L Affinity Capture-Western 16322459 9606 9606 BIOGRID
BIRC5 PRKDC Affinity Capture-Western 20394854 9606 9606 BIOGRID
BIRC5 MDC1 Affinity Capture-Western 20394854 9606 9606 BIOGRID
BIRC5 XRCC6 Affinity Capture-Western 20394854 9606 9606 BIOGRID
BIRC5 H2AFX Affinity Capture-Western 20394854 9606 9606 BIOGRID
BIRC5 XPO1 Reconstituted Complex 17099693 9606 9606 BIOGRID
BIRC5 XPO1 Affinity Capture-Western 17099693 9606 9606 BIOGRID
BIRC5 AURKB Affinity Capture-Western 17099693 9606 9606 BIOGRID
BIRC5 INCENP Affinity Capture-Western 17099693 9606 9606 BIOGRID
BIRC5 CDCA8 Affinity Capture-Western 17099693 9606 9606 BIOGRID
BIRC5 BIRC5 Reconstituted Complex 17099693 9606 9606 BIOGRID
BIRC5 AURKB Reconstituted Complex 17099693 9606 9606 BIOGRID
BIRC5 INCENP Reconstituted Complex 17099693 9606 9606 BIOGRID
BIRC5 CDCA8 Reconstituted Complex 17099693 9606 9606 BIOGRID
BIRC5 BIRC2 Affinity Capture-Western 15665297 9606 9606 BIOGRID
BIRC5 HIST2H3C Reconstituted Complex 20929775 9606 9606 BIOGRID
BIRC5 INCENP Reconstituted Complex 16571674 9606 9606 BIOGRID
BIRC5 CDCA8 Reconstituted Complex 16571674 9606 9606 BIOGRID
BIRC5 BIRC5 Affinity Capture-Western 16571674 9606 9606 BIOGRID
BIRC5 BIRC5 Reconstituted Complex 16291752 9606 9606 BIOGRID
BIRC5 BIRC5 Affinity Capture-Western 16291752 9606 9606 BIOGRID
BIRC5 CDCA8 Affinity Capture-Western 16291752 9606 9606 BIOGRID
BIRC5 AURKB Affinity Capture-Western 16291752 9606 9606 BIOGRID
BIRC5 F2RL1 Affinity Capture-Western 20826780 9606 9606 BIOGRID
BIRC5 CDCA8 Reconstituted Complex 20430883 9606 9606 BIOGRID
BIRC5 AIP Affinity Capture-Western 19366855 9606 9606 BIOGRID
BIRC5 BIRC5 Reconstituted Complex 21536684 9606 9606 BIOGRID
BIRC5 DIABLO Reconstituted Complex 21536684 9606 9606 BIOGRID
BIRC5 DIABLO FRET 21536684 9606 9606 BIOGRID
BIRC5 BIRC5 Reconstituted Complex 23251006 9606 9606 BIOGRID
BIRC5 RAN Co-localization 23251006 9606 9606 BIOGRID
BIRC5 RAN Affinity Capture-Western 23251006 9606 9606 BIOGRID
BIRC5 CASP9 Co-localization 25241761 9606 9606 BIOGRID
BIRC5 BIRC2 Affinity Capture-Western 25635055 9606 9606 BIOGRID
BIRC5 FBXL7 Affinity Capture-Western 28218735 9606 9606 BIOGRID
BIRC5 CDCA8 Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 CCDC102A Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 INCENP Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 HBZ Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 SSC5D Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 LAMTOR4 Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 PYCARD Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 MED6 Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 MED14 Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 MED10 Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 MED30 Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 MED18 Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 MED8 Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 MED17 Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 MED22 Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 MED21 Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 MED31 Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 MED29 Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 MED20 Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 MED1 Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 MED4 Affinity Capture-MS 28514442 9606 9606 BIOGRID
BIRC5 BIRC5 Reconstituted Complex 14699067 9606 9606 BIOGRID
BIRC5 BIRC5 Affinity Capture-Western 14699067 9606 9606 BIOGRID
BIRC5 DIABLO Reconstituted Complex 14699067 9606 9606 BIOGRID
BIRC5 COPS5 Affinity Capture-Western 29596838 9606 9606 BIOGRID
BIRC5 MAP3K3 Negative Genetic 28319085 9606 9606 BIOGRID
BIRC5 FN3K Negative Genetic 28319085 9606 9606 BIOGRID
BIRC5 MASP2 Negative Genetic 28319085 9606 9606 BIOGRID
BIRC5 CRYBB1 Negative Genetic 28319085 9606 9606 BIOGRID
BIRC5 DCK Negative Genetic 28319085 9606 9606 BIOGRID
BIRC5 PIK3C2B Negative Genetic 28319085 9606 9606 BIOGRID
BIRC5 ERBB2 Negative Genetic 28319085 9606 9606 BIOGRID
BIRC5 CD22 Negative Genetic 28319085 9606 9606 BIOGRID
BIRC5 ATG5 Affinity Capture-Western 23945651 9606 9606 BIOGRID
BIRC5 AURKB Affinity Capture-Western 23945651 9606 9606 BIOGRID
BIRC5 CDCA8 Affinity Capture-Western 23945651 9606 9606 BIOGRID
BIRC5 LAMTOR5 Two-hybrid 32296183 9606 9606 BIOGRID
BIRC5 CCDC85B Two-hybrid 32296183 9606 9606 BIOGRID
BIRC5 STAMBPL1 Affinity Capture-Western 31817770 9606 9606 BIOGRID
BIRC5 INCENP Two-hybrid 11516652 9606 9031 BIOGRID
 Annotation of BIRC5
 TCGA cancer survival map of BIRC5


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  BIRC5