TcoF overview
TcoF: CDK12
GeneID: 1022
Name: Cyclin-dependent kinase 12
Ensembl: ENSG00000167258
Species: Human
Class: class HC
Family: Cyclin
Disease: 7
Go term: 22
Pathway: 1
Hallmark: --
Super Enhancer:

chr17:37616023-37620540 chr17:37641145-37645400 chr17:37606465-37619827 chr17:37605571-37619949 chr17:37603998-37623069

--
Enhancer:

chr17:37786300-37788330 chr17:37824930-37825880 chr17:37815360-37815710 chr17:37815810-37816460 chr17:37375060-37376740 chr17:37555560-37557610 chr17:37605280-37607290 chr17:37673810-37676200 chr17:37872860-37873570 chr17:37213410-37214790 chr17:37785480-37785790 chr17:37810000-37812000 chr17:37896440-37898500 chr17:37319110-37321330 chr17:37814780-37814960 chr17:38176610-38178200 chr17:37649500-37650280 chr17:37932170-37933900 chr17:37949710-37950060 chr17:37950270-37952030 chr17:37274290-37276100 chr17:37640090-37641180 chr17:37641410-37643470 chr17:37955030-37956040 chr17:37956220-37957870 chr17:37661820-37662130 chr17:37829900-37830100 chr17:37863460-37864040 chr17:37866260-37866330 chr17:37871390-37871530 chr17:37882910-37883060 chr17:37883260-37883540 chr17:37885860-37885930 chr17:37886020-37886440 chr17:37922750-37924130 chr17:37924190-37925130 chr17:37925460-37927580 chr17:37943140-37944510 chr17:37946390-37947660 chr17:37964430-37966020 chr17:37974660-37976590 chr17:37984410-37985080 chr17:38045640-38045920 chr17:38071510-38073330 chr17:38100990-38101450 chr17:38102260-38102500 chr17:38102750-38104650 chr17:38104740-38105790 chr17:38106220-38107050 chr17:38107100-38107650 chr17:38119340-38121490 chr17:38128860-38129120 chr17:38279010-38279530 chr17:38279630-38282070 chr17:38444340-38445650 chr17:37830310-37830860 chr17:38059250-38060230 chr17:37785810-37786220 chr17:37826730-37827370 chr17:37849580-37851230 chr17:37886540-37886650 chr17:37270640-37272270 chr17:37286910-37289200 chr17:37293810-37295900 chr17:37299450-37301880 chr17:37619370-37621180 chr17:37519050-37521250 chr17:37404590-37404970 chr17:37230770-37231190 chr17:37364290-37366780 chr17:37380410-37381660 chr17:37532640-37533340 chr17:37533690-37534600 chr17:36617170-36618050 chr17:36618820-36619080 chr17:36619180-36619350 chr17:36619440-36619560 chr17:36620050-36622400 chr17:36623570-36624380 chr17:36624510-36625380 chr17:36625880-36626080 chr17:36626150-36628100 chr17:36642380-36644000 chr17:36694850-36695930 chr17:36705450-36707390 chr17:36716010-36716280 chr17:36716660-36717690 chr17:36728960-36730080 chr17:36733980-36734740 chr17:36753760-36756160 chr17:36772790-36774820 chr17:36813230-36814800 chr17:36814890-36815620 chr17:36816490-36816920 chr17:36849310-36851190 chr17:36863580-36863730 chr17:36864130-36865420 chr17:36865530-36865730 chr17:36865830-36868090 chr17:36876150-36876620 chr17:36877000-36878130 chr17:36881230-36881510 chr17:36886660-36887010 chr17:36995220-36997430 chr17:37905800-37907640 chr17:36716330-36716560 chr17:36863790-36864010 chr17:36879020-36880870 chr17:37813650-37814020 chr17:37872690-37872760 chr17:37814110-37814220 chr17:37815070-37815300 chr17:37814270-37814650 chr17:37399620-37401970 chr17:37254540-37256600 chr17:37800960-37801790 chr17:37237700-37239710 chr17:37049150-37050950 chr17:37053320-37054660 chr17:37169950-37172120 chr17:37172390-37174120 chr17:37252060-37254130 chr17:37317000-37317520 chr17:37331910-37333380 chr17:37481260-37482670 chr17:37174500-37175460 chr17:37872190-37872550 chr17:37797990-37800110 chr17:37800150-37800520

--
Promoter:

chr17:37617739-37721160

False
 ChIP-seq based regulatory details of CDK12
select * from encode where Experiment_target='CDK12'
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
TcoF_00_30343 CDK12 cell line THP-1 GSM1520930 Blood ChIP-Atlas
TcoF_00_30344 CDK12 cell line THP-1 GSM1520931 Blood ChIP-Atlas
TcoF_00_20665 CDK12 cell line Jurkat GSM1850203 Blood Cistrome
 Downstream target genes of CDK12
 Protein-protein interaction of CDK12
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
CDK12 PRPF4 Co-fractionation 22939629 9606 9606 BIOGRID
CDK12 TRIM24 Co-fractionation 22939629 9606 9606 BIOGRID
CDK12 IPPK Co-fractionation 22939629 9606 9606 BIOGRID
CDK12 VPS51 Co-fractionation 22939629 9606 9606 BIOGRID
CDK12 ZNF606 Co-fractionation 22939629 9606 9606 BIOGRID
CDK12 TCEB3 Co-fractionation 22939629 9606 9606 BIOGRID
CDK12 EWSR1 Two-hybrid 21988832 9606 9606 BIOGRID
CDK12 CDK12 Negative Genetic 30033366 9606 9606 BIOGRID
CDK12 CHMP2A Negative Genetic 30033366 9606 9606 BIOGRID
CDK12 EXOSC2 Negative Genetic 30033366 9606 9606 BIOGRID
CDK12 FDPS Negative Genetic 30033366 9606 9606 BIOGRID
CDK12 GNL3L Negative Genetic 30033366 9606 9606 BIOGRID
CDK12 INTS5 Positive Genetic 30033366 9606 9606 BIOGRID
CDK12 LEO1 Negative Genetic 30033366 9606 9606 BIOGRID
CDK12 LIAS Positive Genetic 30033366 9606 9606 BIOGRID
CDK12 MAX Positive Genetic 30033366 9606 9606 BIOGRID
CDK12 MED1 Negative Genetic 30033366 9606 9606 BIOGRID
CDK12 PPP2R1A Negative Genetic 30033366 9606 9606 BIOGRID
CDK12 PSMD1 Negative Genetic 30033366 9606 9606 BIOGRID
CDK12 TBCB Positive Genetic 30033366 9606 9606 BIOGRID
CDK12 TIMM23B Positive Genetic 30033366 9606 9606 BIOGRID
CDK12 KSR1 Negative Genetic 28319085 9606 9606 BIOGRID
CDK12 ERBB2 Negative Genetic 28319085 9606 9606 BIOGRID
CDK12 CDK8 Negative Genetic 28319085 9606 9606 BIOGRID
CDK12 NTRK1 Negative Genetic 28319085 9606 9606 BIOGRID
CDK12 OXT Positive Genetic 28319085 9606 9606 BIOGRID
CDK12 CCNK Affinity Capture-Western 32804079 9606 9606 BIOGRID
 Annotation of CDK12
 TCGA cancer survival map of CDK12


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  CDK12