TcoF overview
| TcoF: | CDK12 | |
| GeneID: | 1022 | |
| Name: | Cyclin-dependent kinase 12 | |
| Ensembl: | ENSG00000167258 | |
| Species: | Human | |
| Class: | class HC | |
| Family: | Cyclin | |
| Disease: | 7 | |
| Go term: | 22 | |
| Pathway: | 1 | |
| Hallmark: | -- | |
| Super Enhancer: |
chr17:37616023-37620540 chr17:37641145-37645400 chr17:37606465-37619827 chr17:37605571-37619949 chr17:37603998-37623069 |
|
| Enhancer: |
chr17:37786300-37788330 chr17:37824930-37825880 chr17:37815360-37815710 chr17:37815810-37816460 chr17:37375060-37376740 chr17:37555560-37557610 chr17:37605280-37607290 chr17:37673810-37676200 chr17:37872860-37873570 chr17:37213410-37214790 chr17:37785480-37785790 chr17:37810000-37812000 chr17:37896440-37898500 chr17:37319110-37321330 chr17:37814780-37814960 chr17:38176610-38178200 chr17:37649500-37650280 chr17:37932170-37933900 chr17:37949710-37950060 chr17:37950270-37952030 chr17:37274290-37276100 chr17:37640090-37641180 chr17:37641410-37643470 chr17:37955030-37956040 chr17:37956220-37957870 chr17:37661820-37662130 chr17:37829900-37830100 chr17:37863460-37864040 chr17:37866260-37866330 chr17:37871390-37871530 chr17:37882910-37883060 chr17:37883260-37883540 chr17:37885860-37885930 chr17:37886020-37886440 chr17:37922750-37924130 chr17:37924190-37925130 chr17:37925460-37927580 chr17:37943140-37944510 chr17:37946390-37947660 chr17:37964430-37966020 chr17:37974660-37976590 chr17:37984410-37985080 chr17:38045640-38045920 chr17:38071510-38073330 chr17:38100990-38101450 chr17:38102260-38102500 chr17:38102750-38104650 chr17:38104740-38105790 chr17:38106220-38107050 chr17:38107100-38107650 chr17:38119340-38121490 chr17:38128860-38129120 chr17:38279010-38279530 chr17:38279630-38282070 chr17:38444340-38445650 chr17:37830310-37830860 chr17:38059250-38060230 chr17:37785810-37786220 chr17:37826730-37827370 chr17:37849580-37851230 chr17:37886540-37886650 chr17:37270640-37272270 chr17:37286910-37289200 chr17:37293810-37295900 chr17:37299450-37301880 chr17:37619370-37621180 chr17:37519050-37521250 chr17:37404590-37404970 chr17:37230770-37231190 chr17:37364290-37366780 chr17:37380410-37381660 chr17:37532640-37533340 chr17:37533690-37534600 chr17:36617170-36618050 chr17:36618820-36619080 chr17:36619180-36619350 chr17:36619440-36619560 chr17:36620050-36622400 chr17:36623570-36624380 chr17:36624510-36625380 chr17:36625880-36626080 chr17:36626150-36628100 chr17:36642380-36644000 chr17:36694850-36695930 chr17:36705450-36707390 chr17:36716010-36716280 chr17:36716660-36717690 chr17:36728960-36730080 chr17:36733980-36734740 chr17:36753760-36756160 chr17:36772790-36774820 chr17:36813230-36814800 chr17:36814890-36815620 chr17:36816490-36816920 chr17:36849310-36851190 chr17:36863580-36863730 chr17:36864130-36865420 chr17:36865530-36865730 chr17:36865830-36868090 chr17:36876150-36876620 chr17:36877000-36878130 chr17:36881230-36881510 chr17:36886660-36887010 chr17:36995220-36997430 chr17:37905800-37907640 chr17:36716330-36716560 chr17:36863790-36864010 chr17:36879020-36880870 chr17:37813650-37814020 chr17:37872690-37872760 chr17:37814110-37814220 chr17:37815070-37815300 chr17:37814270-37814650 chr17:37399620-37401970 chr17:37254540-37256600 chr17:37800960-37801790 chr17:37237700-37239710 chr17:37049150-37050950 chr17:37053320-37054660 chr17:37169950-37172120 chr17:37172390-37174120 chr17:37252060-37254130 chr17:37317000-37317520 chr17:37331910-37333380 chr17:37481260-37482670 chr17:37174500-37175460 chr17:37872190-37872550 chr17:37797990-37800110 chr17:37800150-37800520 |
|
| Promoter: |
chr17:37617739-37721160 |
ChIP-seq based regulatory details of CDK12
| Sample ID | Experiment target | Biosample type | Biosample term name | GSM ID | Tissue type | Source |
|---|---|---|---|---|---|---|
| TcoF_00_30343 | CDK12 | cell line | THP-1 | GSM1520930 | Blood | ChIP-Atlas |
| TcoF_00_30344 | CDK12 | cell line | THP-1 | GSM1520931 | Blood | ChIP-Atlas |
| TcoF_00_20665 | CDK12 | cell line | Jurkat | GSM1850203 | Blood | Cistrome |
Downstream target genes of CDK12
Upstream regulatory details of CDK12
Protein-protein interaction of CDK12
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| CDK12 | PRPF4 | Co-fractionation | 22939629 | 9606 | 9606 | BIOGRID |
| CDK12 | TRIM24 | Co-fractionation | 22939629 | 9606 | 9606 | BIOGRID |
| CDK12 | IPPK | Co-fractionation | 22939629 | 9606 | 9606 | BIOGRID |
| CDK12 | VPS51 | Co-fractionation | 22939629 | 9606 | 9606 | BIOGRID |
| CDK12 | ZNF606 | Co-fractionation | 22939629 | 9606 | 9606 | BIOGRID |
| CDK12 | TCEB3 | Co-fractionation | 22939629 | 9606 | 9606 | BIOGRID |
| CDK12 | EWSR1 | Two-hybrid | 21988832 | 9606 | 9606 | BIOGRID |
| CDK12 | CDK12 | Negative Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| CDK12 | CHMP2A | Negative Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| CDK12 | EXOSC2 | Negative Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| CDK12 | FDPS | Negative Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| CDK12 | GNL3L | Negative Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| CDK12 | INTS5 | Positive Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| CDK12 | LEO1 | Negative Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| CDK12 | LIAS | Positive Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| CDK12 | MAX | Positive Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| CDK12 | MED1 | Negative Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| CDK12 | PPP2R1A | Negative Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| CDK12 | PSMD1 | Negative Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| CDK12 | TBCB | Positive Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| CDK12 | TIMM23B | Positive Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| CDK12 | KSR1 | Negative Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| CDK12 | ERBB2 | Negative Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| CDK12 | CDK8 | Negative Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| CDK12 | NTRK1 | Negative Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| CDK12 | OXT | Positive Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| CDK12 | CCNK | Affinity Capture-Western | 32804079 | 9606 | 9606 | BIOGRID |
Annotation of CDK12
TCGA cancer survival map of CDK12
Expression of CDK12
Disease information of CDK12