TcoF overview
TcoF: CDK5
GeneID: 1028
Name: Cyclin-dependent kinase 5
Ensembl: ENSG00000164885
Species: Human
Class: class HC
Family: Cyclin
Disease: 5
Go term: 112
Pathway: 27
Hallmark: 3
Super Enhancer:

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Enhancer:

chr7:150777010-150777770 chr7:150785620-150787850 chr7:150773920-150773990 chr7:150711010-150711090 chr7:150715140-150715380 chr7:150760280-150761280 chr7:150940780-150942540 chr7:150775180-150775640 chr7:150264530-150266970 chr7:150691050-150692290 chr7:150693640-150693850 chr7:150694010-150695440 chr7:150707380-150707680 chr7:150707900-150707980 chr7:150708080-150709290 chr7:150715540-150715700 chr7:150737380-150737580 chr7:150749840-150750290 chr7:150923590-150924250 chr7:150939930-150940740 chr7:150972340-150973790 chr7:151078830-151078960 chr7:150710500-150710810 chr7:150716460-150718270 chr7:150556140-150557130 chr7:150937610-150938570 chr7:151048570-151049890 chr7:151049970-151051540 chr7:151167740-151168470 chr7:150696450-150697340 chr7:150704360-150706010 chr7:150748040-150748120 chr7:150748180-150748250 chr7:150748410-150748890 chr7:150714360-150714950 chr7:150776110-150776580 chr7:150833480-150835220 chr7:150774120-150774180 chr7:150774320-150774390 chr7:150774490-150774700 chr7:150813940-150814180 chr7:150814270-150814450 chr7:150699390-150700230 chr7:150765140-150767030 chr7:150522230-150524220 chr7:150642600-150643960 chr7:151065060-151065820 chr7:151135730-151136980 chr7:150810050-150812110 chr7:150812130-150813870 chr7:150869640-150871340 chr7:151038930-151041330 chr7:150360450-150362550 chr7:150814860-150815290 chr7:150771930-150772340 chr7:150772600-150772690 chr7:150772860-150773090 chr7:150773270-150773370 chr7:150773620-150773700 chr7:150774870-150774960 chr7:150775790-150775920 chr7:150820730-150820880 chr7:150835400-150837060 chr7:150701020-150703510 chr7:150706360-150706480 chr7:150706670-150707200 chr7:151010810-151011290 chr7:151061890-151064020 chr7:151121950-151122370 chr7:151181890-151183980 chr7:151188100-151189930 chr7:150788030-150789570 chr7:151024070-151025210 chr7:151208460-151210910 chr7:150895760-150897960 chr7:151042550-151044970 chr7:150863640-150864090 chr7:150424390-150425320 chr7:150484290-150486530 chr7:150527570-150528550 chr7:150549650-150550400 chr7:150605940-150607960 chr7:150638440-150640600 chr7:150665240-150666590 chr7:150706150-150706270 chr7:150712210-150712440 chr7:150907320-150908120 chr7:150922080-150923390 chr7:150938740-150938960 chr7:151064210-151064940 chr7:151082370-151084860 chr7:151085200-151086760 chr7:151090450-151091880 chr7:151091900-151092860 chr7:151093280-151095560 chr7:151095640-151096720 chr7:151099210-151101250 chr7:151165220-151166100 chr7:151166160-151167650 chr7:151168520-151168620 chr7:151168690-151171120 chr7:151179900-151180520 chr7:151181560-151181800 chr7:151184020-151184630 chr7:151185000-151185220 chr7:151190140-151190460 chr7:151192900-151193080 chr7:151193180-151193390 chr7:151194160-151196600 chr7:151200050-151202000 chr7:151234730-151236950 chr7:151303290-151304220 chr7:151304300-151306150 chr7:151392970-151395060 chr7:151412340-151414130 chr7:151422820-151423480 chr7:151423520-151425700 chr7:151493140-151495620 chr7:151504890-151507050 chr7:151637140-151638370 chr7:151691120-151692060 chr7:150650310-150652480 chr7:151191290-151191590 chr7:150738320-150739040 chr7:151067340-151068930 chr7:150520290-150522100 chr7:150646140-150646510 chr7:150692400-150692600 chr7:151046330-151048500 chr7:150600410-150602350 chr7:150713910-150714120 chr7:150737720-150737910 chr7:150796490-150796860 chr7:150796950-150797620 chr7:151443500-151444980 chr7:150956890-150957470 chr7:150921200-150921860 chr7:151097330-151098960 chr7:150634620-150636720 chr7:150641180-150642040 chr7:150451890-150454310 chr7:150597880-150600240 chr7:150954360-150956640 chr7:150644140-150644410 chr7:150644600-150644690 chr7:150645630-150645940 chr7:150647510-150648000 chr7:150682440-150683140 chr7:150628110-150629220 chr7:150957950-150959780 chr7:150731520-150731590 chr7:150731690-150731810 chr7:150731920-150732660 chr7:150695540-150695620 chr7:150697690-150698310 chr7:150703580-150703970 chr7:150713620-150713770 chr7:151070470-151071180 chr7:151071330-151072150 chr7:151073320-151073710 chr7:150327230-150329250 chr7:150384170-150386640 chr7:150416170-150417130 chr7:150438010-150439270

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Promoter:

chr7:150750902-150754984

False
 ChIP-seq based regulatory details of CDK5
select * from encode where Experiment_target='CDK5'
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
 Downstream target genes of CDK5
 Protein-protein interaction of CDK5
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
CDK5 LMTK2 Two-hybrid 12832520 9606 9606 BIOGRID
CDK5 LMTK2 Reconstituted Complex 12832520 9606 9606 BIOGRID
CDK5 NES Biochemical Activity 12832492 9606 9606 BIOGRID
CDK5 NDEL1 Biochemical Activity 11163260 9606 9606 BIOGRID
CDK5 CDK5R1 Affinity Capture-Western 11389014 9606 9606 BIOGRID
CDK5 CCND2 Affinity Capture-Western 9422379 9606 9606 BIOGRID
CDK5 PAK1 Biochemical Activity 11604394 9606 9606 BIOGRID
CDK5 PAK1 Affinity Capture-Western 11604394 9606 9606 BIOGRID
CDK5 CDK16 Biochemical Activity 12084709 9606 9606 BIOGRID
CDK5 CDK5R1 Affinity Capture-Western 11583627 9606 9606 BIOGRID
CDK5 CDK5R1 Co-crystal Structure 11583627 9606 9606 BIOGRID
CDK5 TP53 Affinity Capture-Western 17591690 9606 9606 BIOGRID
CDK5 CDK5R1 Affinity Capture-Western 17591690 9606 9606 BIOGRID
CDK5 PARK2 Biochemical Activity 17327227 9606 9606 BIOGRID
CDK5 NES Affinity Capture-Western 17036052 9606 9606 BIOGRID
CDK5 TLN1 Biochemical Activity 19363486 9606 9606 BIOGRID
CDK5 BAG6 Two-hybrid 21900206 9606 9606 BIOGRID
CDK5 ALAS1 Two-hybrid 21900206 9606 9606 BIOGRID
CDK5 H1F0 Biochemical Activity 12970441 9606 9606 BIOGRID
CDK5 CDK5R1 Affinity Capture-Western 22654103 9606 9606 BIOGRID
CDK5 FZR1 Affinity Capture-Western 22654103 9606 9606 BIOGRID
CDK5 RPL34 Two-hybrid 10049762 9606 9606 BIOGRID
CDK5 RB1 Biochemical Activity 10049762 9606 9606 BIOGRID
CDK5 DAB1 Biochemical Activity 18076569 9606 9606 BIOGRID
CDK5 DNM1 Biochemical Activity 15834155 9606 9606 BIOGRID
CDK5 KIF26B Biochemical Activity 22768111 9606 9606 BIOGRID
CDK5 ODF1 Affinity Capture-Western 17762160 9606 9606 BIOGRID
CDK5 CDK5R1 Affinity Capture-Western 17762160 9606 9606 BIOGRID
CDK5 AMPH Biochemical Activity 17419807 9606 9606 BIOGRID
CDK5 MAPT Biochemical Activity 9735171 9606 9606 BIOGRID
CDK5 MBP Biochemical Activity 17906618 9606 9606 BIOGRID
CDK5 HTRA2 Biochemical Activity 17906618 9606 9606 BIOGRID
CDK5 APP Reconstituted Complex 21832049 9606 9606 BIOGRID
CDK5 GBP1 Co-fractionation 22939629 9606 9606 BIOGRID
CDK5 MAPT Biochemical Activity 12387894 9606 9606 BIOGRID
CDK5 CDKN1B Biochemical Activity 23543736 9606 9606 BIOGRID
CDK5 HIST1H1B Biochemical Activity 11516829 9606 9606 BIOGRID
CDK5 PPARG Affinity Capture-Western 22078880 9606 9606 BIOGRID
CDK5 CDK5 Affinity Capture-MS 23602568 9606 9606 BIOGRID
CDK5 CDKN1A Affinity Capture-MS 23602568 9606 9606 BIOGRID
CDK5 CDKN1B Affinity Capture-MS 23602568 9606 9606 BIOGRID
CDK5 C2CD5 Affinity Capture-MS 23602568 9606 9606 BIOGRID
CDK5 CCNB1 Affinity Capture-MS 23602568 9606 9606 BIOGRID
CDK5 CABLES1 Affinity Capture-MS 23602568 9606 9606 BIOGRID
CDK5 FIBP Affinity Capture-MS 23602568 9606 9606 BIOGRID
CDK5 KIAA0195 Affinity Capture-MS 23602568 9606 9606 BIOGRID
CDK5 CABLES2 Affinity Capture-MS 23602568 9606 9606 BIOGRID
CDK5 CCND2 Affinity Capture-MS 23602568 9606 9606 BIOGRID
CDK5 DCLK3 Affinity Capture-MS 23602568 9606 9606 BIOGRID
CDK5 CCND3 Affinity Capture-MS 23602568 9606 9606 BIOGRID
CDK5 CDK5R1 Affinity Capture-MS 23602568 9606 9606 BIOGRID
CDK5 STIP1 Affinity Capture-MS 23602568 9606 9606 BIOGRID
CDK5 CCNE1 Affinity Capture-MS 23602568 9606 9606 BIOGRID
CDK5 FIBP Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 GLUD1 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 HSP90AA1 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 HSP90AB1 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 CCNB1 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 TCP1 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 CCNA2 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 CCND2 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 CCND3 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 CDKN1A Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 CCT6A Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 CDKN1B Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 CCT5 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 CCT3 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 CCT8 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 CCT4 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 CCT2 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 CDK3 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 CDK18 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 KIAA0195 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 TRAP1 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 C2CD5 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 CABLES1 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 CCT7 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 CABLES2 Affinity Capture-MS 23455922 9606 9606 BIOGRID
CDK5 PPARG Biochemical Activity 22584573 9606 9606 BIOGRID
CDK5 MAPT Biochemical Activity 9353289 9606 9606 BIOGRID
CDK5 MAPT Biochemical Activity 19527721 9606 9606 BIOGRID
CDK5 CABLES1 Affinity Capture-MS 25852190 9606 9606 BIOGRID
CDK5 CABLES2 Affinity Capture-MS 25852190 9606 9606 BIOGRID
CDK5 CCNB1 Affinity Capture-MS 25852190 9606 9606 BIOGRID
CDK5 CCNI Affinity Capture-MS 25852190 9606 9606 BIOGRID
CDK5 CCT2 Affinity Capture-MS 25852190 9606 9606 BIOGRID
CDK5 CCT3 Affinity Capture-MS 25852190 9606 9606 BIOGRID
CDK5 CCT4 Affinity Capture-MS 25852190 9606 9606 BIOGRID
CDK5 CCT5 Affinity Capture-MS 25852190 9606 9606 BIOGRID
CDK5 CCT6A Affinity Capture-MS 25852190 9606 9606 BIOGRID
CDK5 CCT7 Affinity Capture-MS 25852190 9606 9606 BIOGRID
CDK5 CCT8 Affinity Capture-MS 25852190 9606 9606 BIOGRID
CDK5 CDK3 Affinity Capture-MS 25852190 9606 9606 BIOGRID
CDK5 CDKN1B Affinity Capture-MS 25852190 9606 9606 BIOGRID
CDK5 FIBP Affinity Capture-MS 25852190 9606 9606 BIOGRID
CDK5 KIAA0195 Affinity Capture-MS 25852190 9606 9606 BIOGRID
CDK5 C2CD5 Affinity Capture-MS 25852190 9606 9606 BIOGRID
CDK5 MAPT Biochemical Activity 17078951 9606 9606 BIOGRID
CDK5 C2CD5 Affinity Capture-MS 26186194 9606 9606 BIOGRID
CDK5 CCNB1 Affinity Capture-MS 26186194 9606 9606 BIOGRID
CDK5 CDKN1B Affinity Capture-MS 26186194 9606 9606 BIOGRID
CDK5 CABLES1 Affinity Capture-MS 26186194 9606 9606 BIOGRID
CDK5 CDK20 Affinity Capture-MS 26186194 9606 9606 BIOGRID
CDK5 CDK14 Affinity Capture-MS 26186194 9606 9606 BIOGRID
CDK5 RPE Co-fractionation 26344197 9606 9606 BIOGRID
CDK5 STUB1 Affinity Capture-Western 26206088 9606 9606 BIOGRID
CDK5 FZR1 Affinity Capture-Western 18818692 9606 9606 BIOGRID
CDK5 FZR1 Biochemical Activity 18818692 9606 9606 BIOGRID
CDK5 CDC25A Biochemical Activity 22899714 9606 9606 BIOGRID
CDK5 CDC25B Biochemical Activity 22899714 9606 9606 BIOGRID
CDK5 CDC25C Biochemical Activity 22899714 9606 9606 BIOGRID
CDK5 YBX3 Two-hybrid 10100871 9606 9606 BIOGRID
CDK5 C2CD5 Affinity Capture-MS 28514442 9606 9606 BIOGRID
CDK5 CABLES1 Affinity Capture-MS 28514442 9606 9606 BIOGRID
CDK5 CCNB1 Affinity Capture-MS 28514442 9606 9606 BIOGRID
CDK5 CDK20 Affinity Capture-MS 28514442 9606 9606 BIOGRID
CDK5 CDKN1B Affinity Capture-MS 28514442 9606 9606 BIOGRID
CDK5 CDK3 Affinity Capture-MS 28514442 9606 9606 BIOGRID
CDK5 CDK14 Affinity Capture-MS 28514442 9606 9606 BIOGRID
CDK5 CCNE1 Affinity Capture-MS 28514442 9606 9606 BIOGRID
CDK5 SH3GLB1 Affinity Capture-MS 27173435 9606 9606 BIOGRID
CDK5 PRCC Affinity Capture-MS 27173435 9606 9606 BIOGRID
CDK5 SEPT7 Affinity Capture-MS 27173435 9606 9606 BIOGRID
CDK5 CHORDC1 Affinity Capture-MS 27173435 9606 9606 BIOGRID
CDK5 SARNP Affinity Capture-MS 27173435 9606 9606 BIOGRID
CDK5 COPZ1 Affinity Capture-MS 27173435 9606 9606 BIOGRID
CDK5 GORASP2 Affinity Capture-MS 27173435 9606 9606 BIOGRID
CDK5 SEPT11 Affinity Capture-MS 27173435 9606 9606 BIOGRID
CDK5 DRG1 Affinity Capture-MS 27173435 9606 9606 BIOGRID
CDK5 PIKFYVE Biochemical Activity 28637746 9606 9606 BIOGRID
CDK5 CDK5R1 Reconstituted Complex 28637746 9606 9606 BIOGRID
CDK5 CCND2 Two-hybrid 26871637 9606 9606 BIOGRID
CDK5 HMGA1 Negative Genetic 28319085 9606 9606 BIOGRID
CDK5 NDUFA4L2 Positive Genetic 28319085 9606 9606 BIOGRID
CDK5 EGFR Positive Genetic 28319085 9606 9606 BIOGRID
CDK5 IGF1R Positive Genetic 28319085 9606 9606 BIOGRID
CDK5 PIK3CA Positive Genetic 28319085 9606 9606 BIOGRID
CDK5 MAPT Biochemical Activity 17045592 9606 9606 BIOGRID
CDK5 MAPT Biochemical Activity 9614189 9606 9606 BIOGRID
CDK5 MAPT Biochemical Activity 16262633 9606 9606 BIOGRID
CDK5 AATK Biochemical Activity 14521924 9606 9606 BIOGRID
CDK5 AATK Affinity Capture-Western 14521924 9606 9606 BIOGRID
CDK5 LRRK2 Affinity Capture-Western 26268594 9606 9606 BIOGRID
CDK5 MAPT Affinity Capture-Western 26268594 9606 9606 BIOGRID
CDK5 CDK5R1 Biochemical Activity 10604467 9606 9606 BIOGRID
CDK5 HIST1H1A Biochemical Activity 10604467 9606 9606 BIOGRID
CDK5 CDK5R1 FRET 25331900 9606 9606 BIOGRID
CDK5 MAPT Reconstituted Complex 16519508 9606 9606 BIOGRID
CDK5 GSK3B Affinity Capture-Western 16519508 9606 9606 BIOGRID
CDK5 PPARG Biochemical Activity 23178929 9606 9606 BIOGRID
CDK5 MAPT Biochemical Activity 11943163 9606 9606 BIOGRID
CDK5 SPDYE4 Two-hybrid 32296183 9606 9606 BIOGRID
CDK5 TRIM59 Reconstituted Complex 31488827 9606 9606 BIOGRID
CDK5 TRIM59 Affinity Capture-Western 31488827 9606 9606 BIOGRID
CDK5 TRIM59 Biochemical Activity 31488827 9606 9606 BIOGRID
CDK5 FKBP5 Affinity Capture-Western 26602018 9606 9606 BIOGRID
CDK5 FKBP4 Affinity Capture-Western 26602018 9606 9606 BIOGRID
CDK5 BRCC3 Affinity Capture-Western 31787240 9606 9606 BIOGRID
CDK5 PPARG Biochemical Activity 31319193 9606 9606 BIOGRID
CDK5 PPARG Reconstituted Complex 31319193 9606 9606 BIOGRID
CDK5 CDK5R1 Reconstituted Complex 31319193 9606 9606 BIOGRID
CDK5 Suds3 Biochemical Activity 15489224 9606 10090 BIOGRID
 Annotation of CDK5
 TCGA cancer survival map of CDK5


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  CDK5