TcoF overview
| TcoF: | CHUK | |
| GeneID: | 10987 | |
| Name: | Inhibitor of nuclear factor kappa-B kinase subunit alpha | |
| Ensembl: | ENSG00000213341 | |
| Species: | Human | |
| Class: | class HC | |
| Family: | Others | |
| Disease: | 10 | |
| Go term: | 56 | |
| Pathway: | 103 | |
| Hallmark: | 1 | |
| Super Enhancer: |
chr10:101962606-101966228 |
|
| Enhancer: |
chr10:102054880-102055870 chr10:102056050-102056730 chr10:102107290-102107820 chr10:102114390-102116280 chr10:101967090-101969350 chr10:101943600-101945270 chr10:101950820-101953050 chr10:102051470-102052700 chr10:102240880-102241660 chr10:102241810-102242020 chr10:101937950-101938950 chr10:102009480-102010000 chr10:102010090-102010230 chr10:102112250-102114180 chr10:102025050-102027320 chr10:102044320-102045850 chr10:102133770-102135850 chr10:102295890-102296160 chr10:102286830-102289130 chr10:102289260-102289520 chr10:101927160-101928440 chr10:101723550-101723820 chr10:101723930-101724210 chr10:101934040-101935700 chr10:102267810-102268760 chr10:101602600-101603550 chr10:101871100-101871940 chr10:101923850-101925220 chr10:101310470-101312080 chr10:101419350-101419610 chr10:101419720-101421200 chr10:101421390-101423630 chr10:101426190-101427800 chr10:101440600-101443100 chr10:101451280-101451650 chr10:101452700-101455040 chr10:101455570-101455710 chr10:101527060-101529150 chr10:101542640-101544360 chr10:101544540-101546900 chr10:101648100-101648580 chr10:101665700-101667680 chr10:101679830-101681970 chr10:101704340-101706050 chr10:102108550-102110290 chr10:102110820-102111200 chr10:102262240-102264740 chr10:102266180-102267180 chr10:102413500-102414640 chr10:102439930-102441640 chr10:101547760-101549460 chr10:101677400-101679600 chr10:101742350-101744850 chr10:102414660-102416570 chr10:101569980-101571290 chr10:101735180-101737610 chr10:101737680-101737990 chr10:101740960-101742170 chr10:102072520-102073510 chr10:102142010-102142440 chr10:101443450-101445540 chr10:101591890-101594130 chr10:101594290-101595840 chr10:101725400-101727800 chr10:101907480-101909840 chr10:101608780-101610350 chr10:102296420-102297590 chr10:101640120-101642390 chr10:102299600-102300390 chr10:102300540-102301130 chr10:101878600-101880920 chr10:101763740-101765290 chr10:102314490-102316380 chr10:101628980-101631240 chr10:101672910-101674070 chr10:102244420-102246400 chr10:102384740-102387100 chr10:101890210-101890970 chr10:101912110-101914610 chr10:101895090-101895810 chr10:101935830-101936260 |
|
| Promoter: |
chr10:101948057-101989353 |
ChIP-seq based regulatory details of CHUK
| Sample ID | Experiment target | Biosample type | Biosample term name | GSM ID | Tissue type | Source |
|---|
Downstream target genes of CHUK
Upstream regulatory details of CHUK
Protein-protein interaction of CHUK
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| CHUK | PPM1B | Affinity Capture-Western | 14585847 | 9606 | 9606 | BIOGRID |
| CHUK | MAP3K14 | Affinity Capture-Western | 9244310 | 9606 | 9606 | BIOGRID |
| CHUK | TRAF2 | Affinity Capture-Western | 9244310 | 9606 | 9606 | BIOGRID |
| CHUK | MAP3K8 | Affinity Capture-Western | 10072079 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 9252186 | 9606 | 9606 | BIOGRID |
| CHUK | IRS1 | Affinity Capture-Western | 12351658 | 9606 | 9606 | BIOGRID |
| CHUK | NLRP4 | Affinity Capture-Western | 12093792 | 9606 | 9606 | BIOGRID |
| CHUK | CDC37 | Reconstituted Complex | 11864612 | 9606 | 9606 | BIOGRID |
| CHUK | PRKDC | Reconstituted Complex | 9632806 | 9606 | 9606 | BIOGRID |
| CHUK | CHUK | Affinity Capture-Western | 10755617 | 9606 | 9606 | BIOGRID |
| CHUK | MAP3K14 | Affinity Capture-Western | 10887201 | 9606 | 9606 | BIOGRID |
| CHUK | EIF2AK2 | Affinity Capture-Western | 10848580 | 9606 | 9606 | BIOGRID |
| CHUK | CASP8 | Affinity Capture-Western | 11002417 | 9606 | 9606 | BIOGRID |
| CHUK | NCOA3 | Reconstituted Complex | 11971985 | 9606 | 9606 | BIOGRID |
| CHUK | NCOA3 | Biochemical Activity | 11971985 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKB | Reconstituted Complex | 10968790 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKB | Affinity Capture-Western | 10968790 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 9346485 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIB | Biochemical Activity | 9346485 | 9606 | 9606 | BIOGRID |
| CHUK | CHUK | Affinity Capture-Western | 9346485 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKB | Affinity Capture-Western | 9346485 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKG | Co-purification | 11057907 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKB | Co-purification | 11057907 | 9606 | 9606 | BIOGRID |
| CHUK | MAP3K7 | Affinity Capture-Western | 10094049 | 9606 | 9606 | BIOGRID |
| CHUK | MAP3K14 | Affinity Capture-Western | 10094049 | 9606 | 9606 | BIOGRID |
| CHUK | CHUK | Biochemical Activity | 11585904 | 9606 | 9606 | BIOGRID |
| CHUK | CUL1 | Affinity Capture-Western | 17914462 | 9606 | 9606 | BIOGRID |
| CHUK | TP73 | Affinity Capture-Western | 17452332 | 9606 | 9606 | BIOGRID |
| CHUK | AKT1 | Affinity Capture-Western | 15800029 | 9606 | 9606 | BIOGRID |
| CHUK | RELA | Biochemical Activity | 16382138 | 9606 | 9606 | BIOGRID |
| CHUK | NCOR2 | Biochemical Activity | 16382138 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 12054687 | 9606 | 9606 | BIOGRID |
| CHUK | NCOR2 | Biochemical Activity | 15494311 | 9606 | 9606 | BIOGRID |
| CHUK | RELA | Biochemical Activity | 15489227 | 9606 | 9606 | BIOGRID |
| CHUK | HIST2H3C | Affinity Capture-Western | 17643371 | 9606 | 9606 | BIOGRID |
| CHUK | HIST2H3C | Reconstituted Complex | 17643371 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKB | Reconstituted Complex | 9346484 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKB | Affinity Capture-Western | 9751060 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKG | Affinity Capture-Western | 9751060 | 9606 | 9606 | BIOGRID |
| CHUK | MAP3K7 | Affinity Capture-Western | 9742107 | 9606 | 9606 | BIOGRID |
| CHUK | PRKCA | Reconstituted Complex | 10022904 | 9606 | 9606 | BIOGRID |
| CHUK | PRKCI | Reconstituted Complex | 10022904 | 9606 | 9606 | BIOGRID |
| CHUK | PRKCD | Reconstituted Complex | 10022904 | 9606 | 9606 | BIOGRID |
| CHUK | PRKCA | Affinity Capture-Western | 10022904 | 9606 | 9606 | BIOGRID |
| CHUK | PRKCI | Affinity Capture-Western | 10022904 | 9606 | 9606 | BIOGRID |
| CHUK | PRKCD | Affinity Capture-Western | 10022904 | 9606 | 9606 | BIOGRID |
| CHUK | HTT | Biochemical Activity | 20026656 | 9606 | 9606 | BIOGRID |
| CHUK | COPS5 | Biochemical Activity | 19656241 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 20932476 | 9606 | 9606 | BIOGRID |
| CHUK | IRF5 | Affinity Capture-Western | 19786094 | 9606 | 9606 | BIOGRID |
| CHUK | TRIM40 | Affinity Capture-Western | 21474709 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKG | Affinity Capture-Western | 19815509 | 9606 | 9606 | BIOGRID |
| CHUK | CDC37 | Affinity Capture-MS | 21903422 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKB | Affinity Capture-MS | 21903422 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKG | Affinity Capture-MS | 21903422 | 9606 | 9606 | BIOGRID |
| CHUK | RELA | Affinity Capture-MS | 21903422 | 9606 | 9606 | BIOGRID |
| CHUK | NCOA3 | Biochemical Activity | 15383283 | 9606 | 9606 | BIOGRID |
| CHUK | TRAF6 | Affinity Capture-Western | 15836773 | 9606 | 9606 | BIOGRID |
| CHUK | TAB2 | Affinity Capture-Western | 15836773 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 18501560 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKG | Biochemical Activity | 16497931 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 15590691 | 9606 | 9606 | BIOGRID |
| CHUK | ERC1 | Affinity Capture-Western | 15218148 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKG | Affinity Capture-Western | 11485410 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIB | Affinity Capture-Western | 11485410 | 9606 | 9606 | BIOGRID |
| CHUK | TP63 | Affinity Capture-Western | 20145131 | 9606 | 9606 | BIOGRID |
| CHUK | MAP3K14 | Affinity Capture-Western | 17563756 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 9914500 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKB | Biochemical Activity | 9914500 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKE | Biochemical Activity | 9914500 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 12138192 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 9689078 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIB | Biochemical Activity | 9689078 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 12190313 | 9606 | 9606 | BIOGRID |
| CHUK | TNIP2 | Affinity Capture-Western | 21784860 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKB | Biochemical Activity | 21784860 | 9606 | 9606 | BIOGRID |
| CHUK | TNIP2 | Biochemical Activity | 21784860 | 9606 | 9606 | BIOGRID |
| CHUK | SRC | Affinity Capture-Western | 12707358 | 9606 | 9606 | BIOGRID |
| CHUK | NLRP2 | Affinity Capture-Western | 15456791 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKB | Affinity Capture-Western | 10733566 | 9606 | 9606 | BIOGRID |
| CHUK | MAP3K1 | Affinity Capture-Western | 9819420 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 17053167 | 9606 | 9606 | BIOGRID |
| CHUK | TRIM27 | Biochemical Activity | 16393995 | 9606 | 9606 | BIOGRID |
| CHUK | TP73 | Affinity Capture-Western | 21482671 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 17384642 | 9606 | 9606 | BIOGRID |
| CHUK | CTNNB1 | Biochemical Activity | 12589056 | 9606 | 9606 | BIOGRID |
| CHUK | FOXO3 | Affinity Capture-Western | 15084260 | 9606 | 9606 | BIOGRID |
| CHUK | TNFRSF1A | Biochemical Activity | 21724995 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 17379600 | 9606 | 9606 | BIOGRID |
| CHUK | NFKB1 | Affinity Capture-Western | 11976329 | 9606 | 9606 | BIOGRID |
| CHUK | NFKB1 | Biochemical Activity | 11976329 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 9721103 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKB | Co-purification | 9721103 | 9606 | 9606 | BIOGRID |
| CHUK | CHUK | Reconstituted Complex | 9721103 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 16354686 | 9606 | 9606 | BIOGRID |
| CHUK | TRAF1 | Affinity Capture-Western | 12709429 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 20133937 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKB | Co-fractionation | 11080499 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKG | Co-fractionation | 11080499 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 11080499 | 9606 | 9606 | BIOGRID |
| CHUK | CREBBP | Affinity Capture-Western | 14597638 | 9606 | 9606 | BIOGRID |
| CHUK | TRADD | Co-fractionation | 10980203 | 9606 | 9606 | BIOGRID |
| CHUK | RIPK1 | Co-fractionation | 10980203 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 11113112 | 9606 | 9606 | BIOGRID |
| CHUK | BCL10 | Affinity Capture-Western | 11113112 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKG | Reconstituted Complex | 17000764 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 20449947 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 18074035 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 15670770 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 12411322 | 9606 | 9606 | BIOGRID |
| CHUK | CARD11 | Affinity Capture-Western | 18625728 | 9606 | 9606 | BIOGRID |
| CHUK | ESR1 | Co-localization | 15808510 | 9606 | 9606 | BIOGRID |
| CHUK | NCOA3 | Co-localization | 15808510 | 9606 | 9606 | BIOGRID |
| CHUK | MAP3K7 | Affinity Capture-Western | 16893890 | 9606 | 9606 | BIOGRID |
| CHUK | MYC | Affinity Capture-Western | 21575199 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKB | Affinity Capture-Western | 21575199 | 9606 | 9606 | BIOGRID |
| CHUK | NCOR1 | Biochemical Activity | 17630505 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 12486103 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKB | Affinity Capture-Western | 12486103 | 9606 | 9606 | BIOGRID |
| CHUK | PYCARD | Affinity Capture-Western | 12486103 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKG | Affinity Capture-Western | 12486103 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 17363905 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 20434986 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 16286467 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 16319058 | 9606 | 9606 | BIOGRID |
| CHUK | TRAF4 | Biochemical Activity | 22547678 | 9606 | 9606 | BIOGRID |
| CHUK | RIPK2 | Biochemical Activity | 22547678 | 9606 | 9606 | BIOGRID |
| CHUK | ERBB2IP | Biochemical Activity | 22547678 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKG | Biochemical Activity | 22547678 | 9606 | 9606 | BIOGRID |
| CHUK | BCL10 | Biochemical Activity | 22547678 | 9606 | 9606 | BIOGRID |
| CHUK | MAP3K4 | Biochemical Activity | 22547678 | 9606 | 9606 | BIOGRID |
| CHUK | PPP1CA | Affinity Capture-Western | 18949366 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKG | Affinity Capture-Western | 18949366 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Affinity Capture-Western | 18949366 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 18003900 | 9606 | 9606 | BIOGRID |
| CHUK | PIAS1 | Affinity Capture-Western | 23032264 | 9606 | 9606 | BIOGRID |
| CHUK | ATG16L2 | Affinity Capture-Western | 23563314 | 9606 | 9606 | BIOGRID |
| CHUK | COPS5 | Affinity Capture-Western | 23636414 | 9606 | 9606 | BIOGRID |
| CHUK | COPS3 | Affinity Capture-Western | 23636414 | 9606 | 9606 | BIOGRID |
| CHUK | SASH1 | Affinity Capture-Western | 23776175 | 9606 | 9606 | BIOGRID |
| CHUK | RPL27 | Two-hybrid | 21988832 | 9606 | 9606 | BIOGRID |
| CHUK | PAX8 | Two-hybrid | 21988832 | 9606 | 9606 | BIOGRID |
| CHUK | CDC73 | Co-fractionation | 22863883 | 9606 | 9606 | BIOGRID |
| CHUK | MYL12A | Co-fractionation | 22863883 | 9606 | 9606 | BIOGRID |
| CHUK | PAF1 | Co-fractionation | 22863883 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 24270572 | 9606 | 9606 | BIOGRID |
| CHUK | HNRNPA1 | Affinity Capture-Western | 24720748 | 9606 | 9606 | BIOGRID |
| CHUK | PSMD9 | Affinity Capture-Western | 24720748 | 9606 | 9606 | BIOGRID |
| CHUK | MTOR | Affinity Capture-Western | 18490760 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 18519641 | 9606 | 9606 | BIOGRID |
| CHUK | RELA | Biochemical Activity | 18519641 | 9606 | 9606 | BIOGRID |
| CHUK | CREBBP | Affinity Capture-Western | 17434128 | 9606 | 9606 | BIOGRID |
| CHUK | CREBBP | Biochemical Activity | 17434128 | 9606 | 9606 | BIOGRID |
| CHUK | NFKB2 | Biochemical Activity | 16651533 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKG | Affinity Capture-Western | 21455180 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 19959994 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 11940602 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Affinity Capture-Western | 24618592 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 15310755 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKB | Affinity Capture-Western | 25748427 | 9606 | 9606 | BIOGRID |
| CHUK | USP18 | Affinity Capture-Western | 26240016 | 9606 | 9606 | BIOGRID |
| CHUK | AKT1 | Affinity Capture-Western | 15710601 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 16219905 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 12624112 | 9606 | 9606 | BIOGRID |
| CHUK | KLHL21 | Affinity Capture-Western | 27387502 | 9606 | 9606 | BIOGRID |
| CHUK | BCL3 | Biochemical Activity | 28689659 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKG | Affinity Capture-Western | 26500060 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKG | Affinity Capture-Western | 28249776 | 9606 | 9606 | BIOGRID |
| CHUK | RNF8 | Affinity Capture-Western | 28499869 | 9606 | 9606 | BIOGRID |
| CHUK | DCUN1D5 | Biochemical Activity | 29958295 | 9606 | 9606 | BIOGRID |
| CHUK | NFKBIA | Biochemical Activity | 29958295 | 9606 | 9606 | BIOGRID |
| CHUK | AMBRA1 | Affinity Capture-Western | 30217973 | 9606 | 9606 | BIOGRID |
| CHUK | AMBRA1 | Biochemical Activity | 30217973 | 9606 | 9606 | BIOGRID |
| CHUK | PPP4C | Affinity Capture-Western | 27391343 | 9606 | 9606 | BIOGRID |
| CHUK | PPP4R2 | Affinity Capture-Western | 27391343 | 9606 | 9606 | BIOGRID |
| CHUK | PPP4R1 | Affinity Capture-Western | 27391343 | 9606 | 9606 | BIOGRID |
| CHUK | PTEN | Affinity Capture-Western | 26787927 | 9606 | 9606 | BIOGRID |
| CHUK | BBC3 | Biochemical Activity | 21997190 | 9606 | 9606 | BIOGRID |
| CHUK | E2F4 | Biochemical Activity | 18542057 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKB | Affinity Capture-Western | 30500824 | 9606 | 9606 | BIOGRID |
| CHUK | KEAP1 | Affinity Capture-Western | 30500824 | 9606 | 9606 | BIOGRID |
| CHUK | IKBKG | Affinity Capture-Western | 30404796 | 9606 | 9606 | BIOGRID |
| CHUK | SKP2 | Affinity Capture-Western | 29474632 | 9606 | 9606 | BIOGRID |
| CHUK | TFRC | Affinity Capture-Western | 23016877 | 9606 | 9606 | BIOGRID |
| CHUK | COPS5 | Affinity Capture-Western | 31950832 | 9606 | 9606 | BIOGRID |
| CHUK | COPS5 | Biochemical Activity | 31950832 | 9606 | 9606 | BIOGRID |
| CHUK | PIAS1 | Affinity Capture-Western | 30982983 | 9606 | 9606 | BIOGRID |
| CHUK | KDF1 | Affinity Capture-Western | 32239614 | 9606 | 9606 | BIOGRID |
| CHUK | Pebp1 | Affinity Capture-Western | 11585904 | 9606 | 10116 | BIOGRID |
Annotation of CHUK
TCGA cancer survival map of CHUK
Expression of CHUK
Disease information of CHUK