TcoF overview
TcoF: COPS2
GeneID: 9150
Name: COP9 signalosome complex subunit 2
Ensembl: ENSG00000166200
Species: Human
Class: class 2
Family: Others
Disease: 2
Go term: 18
Pathway: 2
Hallmark: 1
Super Enhancer:

--
Enhancer:

chr15:49088360-49089490 chr15:49148320-49149880 chr15:49164330-49165290 chr15:49327860-49329780 chr15:49526690-49528040 chr15:49574280-49575760 chr15:49429660-49431720 chr15:49188660-49190940 chr15:49100680-49103150 chr15:49550530-49551110 chr15:49315390-49316050 chr15:49523860-49525320 chr15:49492800-49493350 chr15:49627690-49629180 chr15:49626360-49627610 chr15:48468440-48470270 chr15:48652510-48653500 chr15:48662480-48663290 chr15:48665640-48667380 chr15:48682880-48683420 chr15:48684090-48685380 chr15:48685450-48686880 chr15:48686990-48688890 chr15:48691720-48693050 chr15:48703580-48704760 chr15:48704940-48706930 chr15:48715410-48717560 chr15:48718190-48719760 chr15:48719970-48720540 chr15:48720670-48722860 chr15:48729280-48729510 chr15:48729580-48729960 chr15:48731470-48733240 chr15:48739020-48740960 chr15:48751080-48752440 chr15:48752520-48754240 chr15:48764870-48766450 chr15:48772760-48773850 chr15:48774030-48775140 chr15:48784780-48786400 chr15:48786450-48787310 chr15:48826400-48827620 chr15:48827760-48829800 chr15:48838600-48839160 chr15:48844750-48846840 chr15:48847020-48848960 chr15:48849410-48849890 chr15:48857670-48859610 chr15:48868110-48869140 chr15:48873910-48875730 chr15:48876300-48877040 chr15:48886510-48888470 chr15:48909110-48911010 chr15:48916520-48917940 chr15:48918470-48920720 chr15:48937150-48937770 chr15:48950000-48950670 chr15:48966060-48968450 chr15:48972150-48974520 chr15:48974930-48976850 chr15:48985550-48986340 chr15:48987020-48987970 chr15:48995110-48996420 chr15:49010720-49012740 chr15:49012770-49014160 chr15:49014180-49016550 chr15:49094940-49095610 chr15:49157150-49159330 chr15:49160060-49161320 chr15:49181100-49182940 chr15:49228900-49229640 chr15:49230030-49230440 chr15:49231270-49233700 chr15:49245580-49247660 chr15:49336160-49338470 chr15:49374790-49376800 chr15:49376870-49378590 chr15:49427230-49429220 chr15:49534310-49536060 chr15:49562980-49564320 chr15:49565210-49566900 chr15:49604610-49606540 chr15:49606750-49608560 chr15:49755620-49757480 chr15:49759980-49761450 chr15:49784430-49785960 chr15:49786580-49787830 chr15:49788350-49789280 chr15:48676640-48678870 chr15:48725190-48726790 chr15:48742280-48744750 chr15:48839260-48840920 chr15:48856910-48857380 chr15:48871360-48873770 chr15:48988060-48990450 chr15:49217410-49218770 chr15:48934920-48936800 chr15:49355200-49356860 chr15:49367380-49369600 chr15:49529870-49531410 chr15:49531560-49533010 chr15:49715640-49716220 chr15:49718250-49719320 chr15:49901830-49903410 chr15:49918730-49921080 chr15:50013080-50014120 chr15:50107420-50109320 chr15:48888580-48890510 chr15:49237830-49239200 chr15:49085710-49088200 chr15:49423010-49423460 chr15:49479040-49480730 chr15:49470520-49471260 chr15:49172380-49174060 chr15:49467240-49469400 chr15:49187340-49188250 chr15:49273760-49275040 chr15:49115100-49115930 chr15:49438210-49439180 chr15:49664560-49665060 chr15:49730920-49732090 chr15:49558010-49558600 chr15:49571420-49573110 chr15:49581760-49583340 chr15:49505010-49505660 chr15:49161810-49164060 chr15:49179030-49179780 chr15:49220360-49221640

Promoter:

chr15:49398265-49447858

 ChIP-seq based regulatory details of COPS2
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
TcoF_00_10098 COPS2 cell line K562 - Bone Marrow ENCODE
TcoF_00_10125 COPS2 cell line MCF-7 - Breast ENCODE
TcoF_00_20694 COPS2 cell line K562 - Bone Marrow Cistrome
 Downstream target genes of COPS2
 Protein-protein interaction of COPS2
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
COPS2 NR0B1 Two-hybrid 10713076 9606 9606 BIOGRID
COPS2 NR0B1 Reconstituted Complex 10713076 9606 9606 BIOGRID
COPS2 IRF8 Reconstituted Complex 10991940 9606 9606 BIOGRID
COPS2 NIF3L1 Affinity Capture-Western 12522100 9606 9606 BIOGRID
COPS2 NIF3L1 Reconstituted Complex 12522100 9606 9606 BIOGRID
COPS2 NIF3L1 Two-hybrid 12522100 9606 9606 BIOGRID
COPS2 THRA Reconstituted Complex 10207062 9606 9606 BIOGRID
COPS2 NR2F1 Reconstituted Complex 10207062 9606 9606 BIOGRID
COPS2 SIN3A Affinity Capture-Western 10207062 9606 9606 BIOGRID
COPS2 CUL1 Affinity Capture-Western 16036220 9606 9606 BIOGRID
COPS2 VDR Reconstituted Complex 10877839 9606 9606 BIOGRID
COPS2 THRA Reconstituted Complex 10877839 9606 9606 BIOGRID
COPS2 NCOR1 Reconstituted Complex 10877839 9606 9606 BIOGRID
COPS2 SIN3B Reconstituted Complex 15173382 9606 9606 BIOGRID
COPS2 SIN3A Reconstituted Complex 15173382 9606 9606 BIOGRID
COPS2 COPS3 Affinity Capture-Western 11967155 9606 9606 BIOGRID
COPS2 COPS8 Affinity Capture-Western 11967155 9606 9606 BIOGRID
COPS2 CUL1 Affinity Capture-Western 11967155 9606 9606 BIOGRID
COPS2 CUL2 Affinity Capture-Western 11967155 9606 9606 BIOGRID
COPS2 ABCA1 Affinity Capture-Western 19268428 9606 9606 BIOGRID
COPS2 GPS1 Affinity Capture-MS 16045761 9606 9606 BIOGRID
COPS2 COPS3 Affinity Capture-MS 16045761 9606 9606 BIOGRID
COPS2 COPS4 Affinity Capture-MS 16045761 9606 9606 BIOGRID
COPS2 COPS5 Affinity Capture-MS 16045761 9606 9606 BIOGRID
COPS2 COPS6 Affinity Capture-MS 16045761 9606 9606 BIOGRID
COPS2 COPS8 Affinity Capture-MS 16045761 9606 9606 BIOGRID
COPS2 TP53 Affinity Capture-Western 16045761 9606 9606 BIOGRID
COPS2 JUN Affinity Capture-Western 16045761 9606 9606 BIOGRID
COPS2 CUL1 Affinity Capture-Western 16045761 9606 9606 BIOGRID
COPS2 CUL3 Affinity Capture-Western 16045761 9606 9606 BIOGRID
COPS2 CSNK2A1 Affinity Capture-Western 16045761 9606 9606 BIOGRID
COPS2 EIF3E Affinity Capture-Western 16045761 9606 9606 BIOGRID
COPS2 AR Affinity Capture-Western 17356171 9606 9606 BIOGRID
COPS2 ANAPC1 Affinity Capture-MS 19535905 9606 9606 BIOGRID
COPS2 CDC16 Affinity Capture-MS 19535905 9606 9606 BIOGRID
COPS2 ANAPC4 Affinity Capture-MS 19535905 9606 9606 BIOGRID
COPS2 PSMC5 Affinity Capture-MS 19535905 9606 9606 BIOGRID
COPS2 PSMC3 Affinity Capture-MS 19535905 9606 9606 BIOGRID
COPS2 PSMD5 Affinity Capture-MS 19535905 9606 9606 BIOGRID
COPS2 PSMC1 Affinity Capture-MS 19535905 9606 9606 BIOGRID
COPS2 PSMA6 Affinity Capture-MS 19535905 9606 9606 BIOGRID
COPS2 PSMA6 Affinity Capture-Western 19535905 9606 9606 BIOGRID
COPS2 PSMC3 Affinity Capture-Western 19535905 9606 9606 BIOGRID
COPS2 PSMC1 Affinity Capture-Western 19535905 9606 9606 BIOGRID
COPS2 PSMC5 Affinity Capture-Western 19535905 9606 9606 BIOGRID
COPS2 COPS3 Far Western 10903862 9606 9606 BIOGRID
COPS2 COPS7A Far Western 10903862 9606 9606 BIOGRID
COPS2 MAP3K10 Two-hybrid 15062575 9606 9606 BIOGRID
COPS2 MAP3K10 Reconstituted Complex 15062575 9606 9606 BIOGRID
COPS2 NAP1L1 Reconstituted Complex 17339334 9606 9606 BIOGRID
COPS2 NAP1L1 Affinity Capture-Western 17339334 9606 9606 BIOGRID
COPS2 HIST1H3A Reconstituted Complex 17339334 9606 9606 BIOGRID
COPS2 HIST1H4A Reconstituted Complex 17339334 9606 9606 BIOGRID
COPS2 NPM1 Affinity Capture-MS 17438371 9606 9606 BIOGRID
COPS2 ERCC3 Affinity Capture-MS 17438371 9606 9606 BIOGRID
COPS2 GTF2H2 Affinity Capture-MS 17438371 9606 9606 BIOGRID
COPS2 TRIP11 Affinity Capture-MS 17438371 9606 9606 BIOGRID
COPS2 MED4 Affinity Capture-MS 17438371 9606 9606 BIOGRID
COPS2 MED23 Affinity Capture-MS 17438371 9606 9606 BIOGRID
COPS2 COPS5 Co-fractionation 22939629 9606 9606 BIOGRID
COPS2 COPS6 Co-fractionation 22939629 9606 9606 BIOGRID
COPS2 COPS3 Co-fractionation 22939629 9606 9606 BIOGRID
COPS2 COPS4 Co-fractionation 22939629 9606 9606 BIOGRID
COPS2 COPS8 Co-fractionation 22939629 9606 9606 BIOGRID
COPS2 COPS7A Co-fractionation 22939629 9606 9606 BIOGRID
COPS2 COPS7B Co-fractionation 22939629 9606 9606 BIOGRID
COPS2 SEPT2 Co-fractionation 22939629 9606 9606 BIOGRID
COPS2 SLAIN2 Co-fractionation 22939629 9606 9606 BIOGRID
COPS2 SEPHS1 Co-fractionation 22939629 9606 9606 BIOGRID
COPS2 PFKFB2 Co-fractionation 22939629 9606 9606 BIOGRID
COPS2 EHBP1L1 Co-fractionation 22939629 9606 9606 BIOGRID
COPS2 GAPVD1 Co-fractionation 22939629 9606 9606 BIOGRID
COPS2 PMPCA Co-fractionation 22939629 9606 9606 BIOGRID
COPS2 IRS2 Co-fractionation 22939629 9606 9606 BIOGRID
COPS2 COPS5 Affinity Capture-Western 23408908 9606 9606 BIOGRID
COPS2 SENP8 Affinity Capture-Western 23408908 9606 9606 BIOGRID
COPS2 SENP8 Far Western 23408908 9606 9606 BIOGRID
COPS2 COPS3 Co-fractionation 22863883 9606 9606 BIOGRID
COPS2 COPS4 Co-fractionation 22863883 9606 9606 BIOGRID
COPS2 COPS6 Co-fractionation 22863883 9606 9606 BIOGRID
COPS2 EPB41L1 Co-fractionation 22863883 9606 9606 BIOGRID
COPS2 GPS1 Co-fractionation 22863883 9606 9606 BIOGRID
COPS2 CREBBP Affinity Capture-Western 23441852 9606 9606 BIOGRID
COPS2 CUL4A Reconstituted Complex 25349427 9606 9606 BIOGRID
COPS2 IP6K1 Reconstituted Complex 25349427 9606 9606 BIOGRID
COPS2 COPS8 Affinity Capture-MS 26186194 9606 9606 BIOGRID
COPS2 DCAF4 Affinity Capture-MS 26186194 9606 9606 BIOGRID
COPS2 GPS1 Affinity Capture-MS 26186194 9606 9606 BIOGRID
COPS2 APPBP2 Affinity Capture-MS 26186194 9606 9606 BIOGRID
COPS2 CUL4B Affinity Capture-MS 26186194 9606 9606 BIOGRID
COPS2 CUL4A Affinity Capture-MS 26186194 9606 9606 BIOGRID
COPS2 COPS4 Affinity Capture-MS 26186194 9606 9606 BIOGRID
COPS2 CUL2 Affinity Capture-MS 26186194 9606 9606 BIOGRID
COPS2 COPS3 Affinity Capture-MS 26186194 9606 9606 BIOGRID
COPS2 DDB2 Affinity Capture-MS 26186194 9606 9606 BIOGRID
COPS2 COPS7B Affinity Capture-MS 26186194 9606 9606 BIOGRID
COPS2 COPS7A Affinity Capture-MS 26186194 9606 9606 BIOGRID
COPS2 FEM1B Affinity Capture-MS 26186194 9606 9606 BIOGRID
COPS2 DCAF6 Affinity Capture-MS 26186194 9606 9606 BIOGRID
COPS2 LRR1 Affinity Capture-MS 26186194 9606 9606 BIOGRID
COPS2 DCAF11 Affinity Capture-MS 26186194 9606 9606 BIOGRID
COPS2 FBXO7 Affinity Capture-MS 26186194 9606 9606 BIOGRID
COPS2 BTBD1 Affinity Capture-MS 26186194 9606 9606 BIOGRID
COPS2 BTBD2 Affinity Capture-MS 26186194 9606 9606 BIOGRID
COPS2 COPS3 Co-fractionation 26344197 9606 9606 BIOGRID
COPS2 COPS4 Co-fractionation 26344197 9606 9606 BIOGRID
COPS2 COPS5 Co-fractionation 26344197 9606 9606 BIOGRID
COPS2 COPS6 Co-fractionation 26344197 9606 9606 BIOGRID
COPS2 COPS8 Co-fractionation 26344197 9606 9606 BIOGRID
COPS2 GPS1 Co-fractionation 26344197 9606 9606 BIOGRID
COPS2 MYEOV2 Affinity Capture-Western 26456823 9606 9606 BIOGRID
COPS2 CUL4A FRET 27029275 9606 9606 BIOGRID
COPS2 CUL1 Reconstituted Complex 26976604 9606 9606 BIOGRID
COPS2 CUL2 Reconstituted Complex 26976604 9606 9606 BIOGRID
COPS2 CUL3 Reconstituted Complex 26976604 9606 9606 BIOGRID
COPS2 CUL4A Reconstituted Complex 26976604 9606 9606 BIOGRID
COPS2 COPS5 Reconstituted Complex 26976604 9606 9606 BIOGRID
COPS2 COPS3 Affinity Capture-MS 28514442 9606 9606 BIOGRID
COPS2 LRR1 Affinity Capture-MS 28514442 9606 9606 BIOGRID
COPS2 DCAF4 Affinity Capture-MS 28514442 9606 9606 BIOGRID
COPS2 APPBP2 Affinity Capture-MS 28514442 9606 9606 BIOGRID
COPS2 BTBD1 Affinity Capture-MS 28514442 9606 9606 BIOGRID
COPS2 COPS4 Affinity Capture-MS 28514442 9606 9606 BIOGRID
COPS2 COPS7A Affinity Capture-MS 28514442 9606 9606 BIOGRID
COPS2 GPS1 Affinity Capture-MS 28514442 9606 9606 BIOGRID
COPS2 DDB2 Affinity Capture-MS 28514442 9606 9606 BIOGRID
COPS2 FEM1B Affinity Capture-MS 28514442 9606 9606 BIOGRID
COPS2 DCAF11 Affinity Capture-MS 28514442 9606 9606 BIOGRID
COPS2 CUL4A Affinity Capture-MS 28514442 9606 9606 BIOGRID
COPS2 CUL4B Affinity Capture-MS 28514442 9606 9606 BIOGRID
COPS2 CUL3 Affinity Capture-MS 28514442 9606 9606 BIOGRID
COPS2 FBXO7 Affinity Capture-MS 28514442 9606 9606 BIOGRID
COPS2 BTBD2 Affinity Capture-MS 28514442 9606 9606 BIOGRID
COPS2 CUL2 Affinity Capture-MS 28514442 9606 9606 BIOGRID
COPS2 COPS7B Affinity Capture-MS 27173435 9606 9606 BIOGRID
COPS2 COPS5 Affinity Capture-MS 27173435 9606 9606 BIOGRID
COPS2 COPS4 Affinity Capture-MS 27173435 9606 9606 BIOGRID
COPS2 COPS6 Affinity Capture-MS 27173435 9606 9606 BIOGRID
COPS2 ABCA1 Affinity Capture-Western 27017521 9606 9606 BIOGRID
COPS2 DTL Affinity Capture-MS 16861906 9606 9606 BIOGRID
COPS2 COPS2 Negative Genetic 30033366 9606 9606 BIOGRID
COPS2 CTNNBL1 Positive Genetic 30033366 9606 9606 BIOGRID
COPS2 NDUFA8 Negative Genetic 30033366 9606 9606 BIOGRID
COPS2 PPCS Positive Genetic 30033366 9606 9606 BIOGRID
COPS2 SKA3 Negative Genetic 30033366 9606 9606 BIOGRID
COPS2 UBA3 Positive Genetic 30033366 9606 9606 BIOGRID
COPS2 XRN2 Negative Genetic 30033366 9606 9606 BIOGRID
COPS2 YTHDC1 Negative Genetic 30033366 9606 9606 BIOGRID
COPS2 GPS1 Two-hybrid 32296183 9606 9606 BIOGRID
COPS2 COPS3 Reconstituted Complex 31444342 9606 9606 BIOGRID
COPS2 COPS4 Reconstituted Complex 31444342 9606 9606 BIOGRID
COPS2 COPS7B Reconstituted Complex 31444342 9606 9606 BIOGRID
COPS2 CUL2 Reconstituted Complex 31444342 9606 9606 BIOGRID
COPS2 CUL4A Affinity Capture-Western 32047038 9606 9606 BIOGRID
COPS2 CUL1 Affinity Capture-Western 32047038 9606 9606 BIOGRID
COPS2 CUL2 Affinity Capture-Western 32047038 9606 9606 BIOGRID
COPS2 CUL3 Affinity Capture-Western 32047038 9606 9606 BIOGRID
COPS2 CUL5 Affinity Capture-Western 32047038 9606 9606 BIOGRID
COPS2 GPS1 Reconstituted Complex 32034103 9606 9606 BIOGRID
COPS2 COPS2 Reconstituted Complex 32034103 9606 9606 BIOGRID
COPS2 COPS3 Reconstituted Complex 32034103 9606 9606 BIOGRID
COPS2 COPS4 Reconstituted Complex 32034103 9606 9606 BIOGRID
COPS2 COPS5 Reconstituted Complex 32034103 9606 9606 BIOGRID
COPS2 COPS6 Reconstituted Complex 32034103 9606 9606 BIOGRID
COPS2 COPS7B Reconstituted Complex 32034103 9606 9606 BIOGRID
COPS2 CUL4A Affinity Capture-Western 32493769 9606 9606 BIOGRID
COPS2 Sin3a Reconstituted Complex 10207062 9606 10090 BIOGRID
COPS2 Map3k10 Two-hybrid 15062575 9606 10090 BIOGRID
COPS2 Taf1b Two-hybrid 23441852 9606 10090 BIOGRID
COPS2 5830415F09Rik Two-hybrid 23441852 9606 10090 BIOGRID
COPS2 Crebbp Two-hybrid 23441852 9606 10090 BIOGRID
COPS2 Map3k10 Two-hybrid 23441852 9606 10090 BIOGRID
COPS2 Crebbp Reconstituted Complex 23441852 9606 10090 BIOGRID
 Annotation of COPS2
 TCGA cancer survival map of COPS2


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  COPS2