TcoF overview
TcoF: DHFR
GeneID: 143241
Name: Dihydrofolate reductase
Ensembl: ENSG00000228716
Species: Human
Class: class 3
Family: Others
Disease: 35
Go term: 24
Pathway: 19
Hallmark: 1
Super Enhancer:

chr5:80032538-80056208

Enhancer:

chr5:79910950-79912200 chr5:79915820-79916860 chr5:79864930-79865970 chr5:79886820-79887910 chr5:79968180-79968550 chr5:79903580-79904380 chr5:79850060-79851370 chr5:80083490-80083930 chr5:80093270-80095040 chr5:80096580-80098770 chr5:79857690-79858600 chr5:80042780-80044270 chr5:80054980-80057360 chr5:80406380-80408420 chr5:79955800-79957560 chr5:80032050-80033660 chr5:79845230-79846730 chr5:79971160-79972030 chr5:79929810-79932230 chr5:79966130-79968060 chr5:79997050-79997880 chr5:79999660-80000760 chr5:80159480-80160270 chr5:80166190-80166770 chr5:80285840-80287720 chr5:80301980-80304320 chr5:80316450-80317020 chr5:80118270-80119410

Promoter:

chr5:79922045-79950802

 ChIP-seq based regulatory details of DHFR
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
 Downstream target genes of DHFR
 Protein-protein interaction of DHFR
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
DHFR HSPD1 Reconstituted Complex 8559246 9606 9606 BIOGRID
DHFR HSPD1 Co-purification 8559246 9606 9606 BIOGRID
DHFR MDM2 Reconstituted Complex 18451149 9606 9606 BIOGRID
DHFR TP53 Reconstituted Complex 18451149 9606 9606 BIOGRID
DHFR MDM2 Two-hybrid 18451149 9606 9606 BIOGRID
DHFR MDM2 Affinity Capture-Western 18451149 9606 9606 BIOGRID
DHFR GKAP1 Two-hybrid 25416956 9606 9606 BIOGRID
DHFR CDC73 Synthetic Lethality 27453043 9606 9606 BIOGRID
DHFR CHEK1 Synthetic Lethality 27453043 9606 9606 BIOGRID
DHFR WEE1 Synthetic Lethality 27453043 9606 9606 BIOGRID
 Annotation of DHFR
 TCGA cancer survival map of DHFR


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  DHFR