TcoF overview
TcoF: DTX1
GeneID: 26122
Name: E3 ubiquitin-protein ligase DTX1
Ensembl: ENSG00000135144
Species: Human
Class: class 3
Family: Others
Disease: 9
Go term: 20
Pathway: 6
Hallmark: --
Super Enhancer:

chr12:113490078-113531373 chr12:113493816-113530685 chr12:113488511-113530701 chr12:113494711-113515672 chr12:113486781-113530139 chr12:113487895-113530879 chr12:113484287-113501438 chr12:113487895-113531619 chr12:113485863-113538187 chr12:113486402-113539379 chr12:113485801-113537924 chr12:113485158-113575115 chr12:113486283-113574819 chr12:113477651-113542276 chr12:113485369-113538235 chr12:113486594-113537729 chr12:113486626-113540917 chr12:113486813-113542091 chr12:113486259-113580981 chr12:113485850-113541330 chr12:113485702-113569867 chr12:113485788-113538251 chr12:113485198-113538553 chr12:113492466-113548410 chr12:113486555-113537809 chr12:113504820-113541022 chr12:113506776-113548276 chr12:113485993-113538214 chr12:113485175-113538227

Enhancer:

chr12:113307840-113309240 chr12:113345020-113346340 chr12:113436220-113437980 chr12:113531030-113531340 chr12:113535830-113536620 chr12:113590690-113591010 chr12:113591210-113592210 chr12:113610370-113612440 chr12:113770770-113772790 chr12:113285650-113286970 chr12:113496870-113497780 chr12:113511930-113514410 chr12:113502330-113504010 chr12:113682170-113683270 chr12:113587720-113589720 chr12:113796700-113798520 chr12:113716040-113716570 chr12:113716640-113717060 chr12:113830960-113831690 chr12:113534410-113534510 chr12:113541890-113541960 chr12:113607710-113610150 chr12:113612580-113612670 chr12:113539960-113541750 chr12:113589830-113590580 chr12:113519770-113520440 chr12:113524060-113526330 chr12:113347270-113347600 chr12:113362440-113364770 chr12:113510850-113511740 chr12:113592440-113593060 chr12:113907150-113909130 chr12:113542100-113542840 chr12:113571330-113573200 chr12:113500230-113502220 chr12:113439320-113440730 chr12:113498700-113499400 chr12:113514750-113515220 chr12:113277000-113279230 chr12:113111970-113113980 chr12:113533010-113533120 chr12:113533220-113533520 chr12:113567900-113568680 chr12:113617140-113617280 chr12:113695820-113698170 chr12:113706680-113707560 chr12:113710490-113711030 chr12:113711100-113711370

Promoter:

chr12:113494514-113535833

 ChIP-seq based regulatory details of DTX1
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
 Downstream target genes of DTX1
 Protein-protein interaction of DTX1
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
DTX1 DTX3L Affinity Capture-Western 12670957 9606 9606 BIOGRID
DTX1 DTX1 Affinity Capture-Western 11564735 9606 9606 BIOGRID
DTX1 EP300 Two-hybrid 11564735 9606 9606 BIOGRID
DTX1 GRB2 Two-hybrid 9590294 9606 9606 BIOGRID
DTX1 MAP3K1 Affinity Capture-Western 15684388 9606 9606 BIOGRID
DTX1 MAP3K1 Reconstituted Complex 15684388 9606 9606 BIOGRID
DTX1 NOTCH1 Affinity Capture-Western 20208568 9606 9606 BIOGRID
DTX1 EIF3F Affinity Capture-Western 21124883 9606 9606 BIOGRID
DTX1 ITCH Affinity Capture-Western 17028573 9606 9606 BIOGRID
DTX1 G3BP1 Two-hybrid 21988832 9606 9606 BIOGRID
DTX1 CFLAR Affinity Capture-Western 29374180 9606 9606 BIOGRID
DTX1 NOTCH1 Co-localization 29440432 9606 9606 BIOGRID
DTX1 DTX1 Biochemical Activity 29440432 9606 9606 BIOGRID
DTX1 TMEM126A Affinity Capture-MS 32937373 9606 9606 BIOGRID
DTX1 TOMM20 Affinity Capture-MS 32937373 9606 9606 BIOGRID
 Annotation of DTX1
 TCGA cancer survival map of DTX1


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  DTX1