TcoF overview
| TcoF: | EHMT2 | |
| GeneID: | 55140 | |
| Name: | Histone-lysine N-methyltransferase EHMT2 | |
| Ensembl: | ENSG00000204371 | |
| Species: | Human | |
| Class: | class HC | |
| Family: | Histone lysine methyltransferase | |
| Disease: | 14 | |
| Go term: | 21 | |
| Pathway: | 7 | |
| Hallmark: | -- | |
| Super Enhancer: |
chr6:31762225-31816100 |
|
| Enhancer: |
chr6:31697000-31697820 chr6:31744570-31744880 chr6:31763030-31763320 chr6:31731330-31731840 chr6:31760900-31762600 chr6:31773920-31774530 chr6:31804920-31805010 chr6:31829970-31830390 chr6:31838820-31839090 chr6:32050100-32052180 chr6:32095530-32095890 chr6:31805210-31807310 chr6:31695130-31695310 chr6:31695470-31695940 chr6:31736980-31737450 chr6:31737570-31737770 chr6:31920180-31921500 chr6:31735530-31736790 chr6:31431060-31431140 chr6:32082150-32083040 chr6:32086640-32086730 chr6:32086920-32087600 chr6:31713100-31715160 chr6:31916290-31916600 chr6:31916740-31917010 chr6:31917120-31917190 chr6:31658380-31659350 chr6:31742400-31743100 chr6:31844850-31845330 chr6:31696300-31696420 chr6:31732130-31732210 chr6:31875000-31875610 chr6:31875900-31877660 chr6:31543700-31544310 chr6:31544350-31544540 chr6:31544590-31544890 chr6:31882670-31884820 chr6:31496960-31497520 chr6:31499180-31500550 chr6:31500690-31503140 chr6:31591690-31592030 chr6:31592140-31592220 chr6:31592300-31592940 chr6:31593390-31593560 chr6:31594980-31595540 chr6:31602760-31602900 chr6:31603050-31603170 chr6:31603240-31603350 chr6:31604390-31604500 chr6:31607000-31607270 chr6:31744020-31744320 chr6:31914970-31915120 chr6:31915300-31915510 chr6:31915620-31915720 chr6:31604720-31604810 chr6:31657480-31657850 chr6:31657900-31658310 chr6:31740900-31741010 chr6:31743210-31743740 chr6:31835760-31836600 chr6:31907100-31908720 chr6:32047140-32049140 chr6:32085820-32086550 chr6:32095300-32095440 chr6:32157100-32157470 chr6:32111570-32112900 chr6:31498700-31498820 chr6:31610890-31611660 chr6:31666320-31668710 chr6:31733840-31734020 chr6:31734160-31734230 chr6:31759520-31759640 chr6:31895580-31895730 chr6:31919380-31919650 chr6:31949950-31950080 chr6:31950280-31950490 chr6:31974290-31974390 chr6:31974500-31974580 chr6:32007030-32007130 chr6:32007240-32007320 chr6:32007420-32007520 chr6:32007610-32007780 chr6:32084590-32084810 chr6:32137230-32137740 chr6:31466040-31467810 chr6:31483320-31485600 chr6:31526610-31529060 chr6:31696520-31696640 chr6:31715200-31715620 chr6:31878110-31879970 chr6:31760670-31760760 chr6:31605560-31606800 chr6:31760290-31760530 chr6:31841860-31842230 chr6:31843910-31844010 chr6:31577220-31577990 chr6:31625990-31626070 chr6:31656900-31657350 chr6:31659700-31660800 chr6:31694510-31694810 chr6:32028840-32029170 chr6:32135430-32135680 chr6:31653820-31654720 chr6:31842810-31843620 chr6:31605100-31605220 chr6:31856520-31856740 chr6:31730950-31731190 chr6:31720450-31721070 chr6:31914500-31914780 chr6:32074640-32076950 chr6:31607420-31607970 chr6:31696070-31696220 chr6:32049450-32049810 chr6:31625500-31625840 chr6:31735030-31735130 chr6:31838030-31838370 chr6:31838480-31838580 chr6:32151170-32151330 chr6:32151530-32151650 chr6:32190680-32190780 chr6:31300080-31301230 chr6:31721220-31721340 chr6:31750220-31750300 chr6:31750410-31750490 chr6:31917340-31917820 chr6:31915860-31916150 |
|
| Promoter: |
chr6:31847536-31865464 |
ChIP-seq based regulatory details of EHMT2
| Sample ID | Experiment target | Biosample type | Biosample term name | GSM ID | Tissue type | Source |
|---|---|---|---|---|---|---|
| TcoF_00_10002 | EHMT2 | cell line | A549 | - | Lung | ENCODE |
| TcoF_00_10045 | EHMT2 | cell line | HepG2 | - | Liver | ENCODE |
| TcoF_00_10103 | EHMT2 | cell line | K562 | - | Bone Marrow | ENCODE |
| TcoF_00_40476 | EHMT2 | cell line | A-549 | - | Lung | ReMap |
| TcoF_00_40467 | EHMT2 | cell line | K-562 | - | Bone Marrow | ReMap |
| TcoF_00_20441 | EHMT2 | cell line | HEK293T | GSM1050110 | Embryonic Kidney | Cistrome |
| TcoF_00_20452 | EHMT2 | cell line | HEK293T | GSM1530051 | Embryonic Kidney | Cistrome |
| TcoF_00_20920 | EHMT2 | cell line | MCF-7 | GSM1642516 | Breast | Cistrome |
| TcoF_00_20453 | EHMT2 | cell line | HEK293T | GSM1644649 | Embryonic Kidney | Cistrome |
| TcoF_00_20454 | EHMT2 | cell line | HEK293T | GSM1644650 | Embryonic Kidney | Cistrome |
| TcoF_00_20455 | EHMT2 | cell line | HEK293T | GSM1644651 | Embryonic Kidney | Cistrome |
| TcoF_00_20456 | EHMT2 | cell line | HEK293T | GSM1644652 | Embryonic Kidney | Cistrome |
| TcoF_00_20457 | EHMT2 | cell line | HEK293T | GSM1644657 | Embryonic Kidney | Cistrome |
| TcoF_00_20458 | EHMT2 | cell line | HEK293T | GSM1644658 | Embryonic Kidney | Cistrome |
| TcoF_00_20459 | EHMT2 | cell line | HEK293T | GSM1644659 | Embryonic Kidney | Cistrome |
| TcoF_00_20460 | EHMT2 | cell line | HEK293T | GSM1644660 | Embryonic Kidney | Cistrome |
| TcoF_00_20461 | EHMT2 | cell line | HEK293T | GSM1644665 | Embryonic Kidney | Cistrome |
| TcoF_00_20462 | EHMT2 | cell line | HEK293T | GSM1644666 | Embryonic Kidney | Cistrome |
| TcoF_00_20463 | EHMT2 | cell line | HEK293T | GSM1644669 | Embryonic Kidney | Cistrome |
| TcoF_00_20464 | EHMT2 | cell line | HEK293T | GSM1644670 | Embryonic Kidney | Cistrome |
| TcoF_00_21153 | EHMT2 | cell line | None | GSM2183948 | Colon | Cistrome |
Downstream target genes of EHMT2
Upstream regulatory details of EHMT2
Protein-protein interaction of EHMT2
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| EHMT2 | PRRC2B | Two-hybrid | 16189514 | 9606 | 9606 | BIOGRID |
| EHMT2 | C10orf12 | Two-hybrid | 16189514 | 9606 | 9606 | BIOGRID |
| EHMT2 | THAP7 | Two-hybrid | 16189514 | 9606 | 9606 | BIOGRID |
| EHMT2 | KLF12 | Two-hybrid | 16189514 | 9606 | 9606 | BIOGRID |
| EHMT2 | LNX1 | Two-hybrid | 16189514 | 9606 | 9606 | BIOGRID |
| EHMT2 | CCDC33 | Two-hybrid | 16189514 | 9606 | 9606 | BIOGRID |
| EHMT2 | PRRC2B | Affinity Capture-Western | 16189514 | 9606 | 9606 | BIOGRID |
| EHMT2 | PRDM1 | Affinity Capture-Western | 19124609 | 9606 | 9606 | BIOGRID |
| EHMT2 | HIST1H1E | Biochemical Activity | 19144645 | 9606 | 9606 | BIOGRID |
| EHMT2 | HIST1H1E | Co-purification | 19144645 | 9606 | 9606 | BIOGRID |
| EHMT2 | UHRF1 | Co-localization | 19943104 | 9606 | 9606 | BIOGRID |
| EHMT2 | UHRF1 | Affinity Capture-Western | 19056828 | 9606 | 9606 | BIOGRID |
| EHMT2 | CBX1 | Reconstituted Complex | 19706462 | 9606 | 9606 | BIOGRID |
| EHMT2 | RELB | Co-localization | 19690169 | 9606 | 9606 | BIOGRID |
| EHMT2 | RELB | Reconstituted Complex | 19690169 | 9606 | 9606 | BIOGRID |
| EHMT2 | DNMT1 | Affinity Capture-Western | 17085482 | 9606 | 9606 | BIOGRID |
| EHMT2 | ZNF512B | Two-hybrid | 20211142 | 9606 | 9606 | BIOGRID |
| EHMT2 | MED12 | Affinity Capture-Western | 18691967 | 9606 | 9606 | BIOGRID |
| EHMT2 | WIZ | Affinity Capture-Western | 16702210 | 9606 | 9606 | BIOGRID |
| EHMT2 | CTBP1 | Affinity Capture-Western | 16702210 | 9606 | 9606 | BIOGRID |
| EHMT2 | CTBP2 | Affinity Capture-Western | 16702210 | 9606 | 9606 | BIOGRID |
| EHMT2 | GFI1B | Affinity Capture-Western | 16688220 | 9606 | 9606 | BIOGRID |
| EHMT2 | MED23 | Affinity Capture-Western | 18691967 | 9606 | 9606 | BIOGRID |
| EHMT2 | CDK8 | Affinity Capture-Western | 18691967 | 9606 | 9606 | BIOGRID |
| EHMT2 | MED6 | Affinity Capture-Western | 18691967 | 9606 | 9606 | BIOGRID |
| EHMT2 | MECOM | Affinity Capture-Western | 18619962 | 9606 | 9606 | BIOGRID |
| EHMT2 | GRIP1 | Affinity Capture-Western | 16461774 | 9606 | 9606 | BIOGRID |
| EHMT2 | GFI1 | Affinity Capture-Western | 16287849 | 9606 | 9606 | BIOGRID |
| EHMT2 | ESCO2 | Affinity Capture-Western | 18501190 | 9606 | 9606 | BIOGRID |
| EHMT2 | HIST1H3A | Biochemical Activity | 16185068 | 9606 | 9606 | BIOGRID |
| EHMT2 | EHMT2 | Biochemical Activity | 17962312 | 9606 | 9606 | BIOGRID |
| EHMT2 | CBX5 | Reconstituted Complex | 17962312 | 9606 | 9606 | BIOGRID |
| EHMT2 | CBX1 | Reconstituted Complex | 17962312 | 9606 | 9606 | BIOGRID |
| EHMT2 | CBX3 | Reconstituted Complex | 17962312 | 9606 | 9606 | BIOGRID |
| EHMT2 | CBX5 | Co-localization | 17962312 | 9606 | 9606 | BIOGRID |
| EHMT2 | CBX3 | Co-localization | 17962312 | 9606 | 9606 | BIOGRID |
| EHMT2 | PRDM5 | Affinity Capture-Western | 17636019 | 9606 | 9606 | BIOGRID |
| EHMT2 | KDM1B | Affinity Capture-Western | 20670891 | 9606 | 9606 | BIOGRID |
| EHMT2 | SMC1A | Affinity Capture-Western | 20670891 | 9606 | 9606 | BIOGRID |
| EHMT2 | ESCO1 | Affinity Capture-Western | 20331966 | 9606 | 9606 | BIOGRID |
| EHMT2 | HIST1H3A | Biochemical Activity | 20118233 | 9606 | 9606 | BIOGRID |
| EHMT2 | TP53 | Biochemical Activity | 20118233 | 9606 | 9606 | BIOGRID |
| EHMT2 | POU5F1 | Affinity Capture-RNA | 21151833 | 9606 | 9606 | BIOGRID |
| EHMT2 | HIST3H3 | Biochemical Activity | 12700765 | 9606 | 9606 | BIOGRID |
| EHMT2 | NR0B2 | Affinity Capture-Western | 21566081 | 9606 | 9606 | BIOGRID |
| EHMT2 | SMARCAD1 | Affinity Capture-Western | 21549307 | 9606 | 9606 | BIOGRID |
| EHMT2 | UHRF1 | Affinity Capture-Western | 22064703 | 9606 | 9606 | BIOGRID |
| EHMT2 | UHRF2 | Affinity Capture-Western | 22064703 | 9606 | 9606 | BIOGRID |
| EHMT2 | HIST2H3C | Biochemical Activity | 22387026 | 9606 | 9606 | BIOGRID |
| EHMT2 | DNMT3A | Protein-peptide | 22086334 | 9606 | 9606 | BIOGRID |
| EHMT2 | DNMT3A | Biochemical Activity | 22086334 | 9606 | 9606 | BIOGRID |
| EHMT2 | HIST2H3C | Biochemical Activity | 21495674 | 9606 | 9606 | BIOGRID |
| EHMT2 | HIST2H3C | Biochemical Activity | 15269344 | 9606 | 9606 | BIOGRID |
| EHMT2 | CUX1 | Co-purification | 15269344 | 9606 | 9606 | BIOGRID |
| EHMT2 | MIER1 | Affinity Capture-MS | 21258344 | 9606 | 9606 | BIOGRID |
| EHMT2 | HDAC2 | Affinity Capture-MS | 21258344 | 9606 | 9606 | BIOGRID |
| EHMT2 | WIZ | Affinity Capture-MS | 21258344 | 9606 | 9606 | BIOGRID |
| EHMT2 | EHMT1 | Affinity Capture-MS | 21258344 | 9606 | 9606 | BIOGRID |
| EHMT2 | CDYL | Affinity Capture-MS | 21258344 | 9606 | 9606 | BIOGRID |
| EHMT2 | REST | Affinity Capture-Western | 15200951 | 9606 | 9606 | BIOGRID |
| EHMT2 | CBX5 | Affinity Capture-Western | 15200951 | 9606 | 9606 | BIOGRID |
| EHMT2 | CBX1 | Affinity Capture-Western | 15200951 | 9606 | 9606 | BIOGRID |
| EHMT2 | CBX3 | Affinity Capture-Western | 15200951 | 9606 | 9606 | BIOGRID |
| EHMT2 | CTNNA3 | Affinity Capture-MS | 23718855 | 9606 | 9606 | BIOGRID |
| EHMT2 | PRDM1 | Affinity Capture-Western | 14985713 | 9606 | 9606 | BIOGRID |
| EHMT2 | HIST2H3A | Biochemical Activity | 14985713 | 9606 | 9606 | BIOGRID |
| EHMT2 | HIST1H1A | Biochemical Activity | 14985713 | 9606 | 9606 | BIOGRID |
| EHMT2 | PML | Affinity Capture-Western | 23768491 | 9606 | 9606 | BIOGRID |
| EHMT2 | C10orf12 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| EHMT2 | CHCHD2 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| EHMT2 | KLF3 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| EHMT2 | FAM161A | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| EHMT2 | NAPRT | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| EHMT2 | ZNF785 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| EHMT2 | ZBTB38 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| EHMT2 | RD3 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| EHMT2 | KAT2B | Affinity Capture-Western | 24492005 | 9606 | 9606 | BIOGRID |
| EHMT2 | ABHD17A | Two-hybrid | 21516116 | 9606 | 9606 | BIOGRID |
| EHMT2 | LIG1 | Biochemical Activity | 28803780 | 9606 | 9606 | BIOGRID |
| EHMT2 | AIFM1 | Affinity Capture-MS | 27705803 | 9606 | 9606 | BIOGRID |
| EHMT2 | CSTA | Affinity Capture-MS | 27705803 | 9606 | 9606 | BIOGRID |
| EHMT2 | EHMT1 | Affinity Capture-MS | 27705803 | 9606 | 9606 | BIOGRID |
| EHMT2 | LACRT | Affinity Capture-MS | 27705803 | 9606 | 9606 | BIOGRID |
| EHMT2 | PIP | Affinity Capture-MS | 27705803 | 9606 | 9606 | BIOGRID |
| EHMT2 | PSMB3 | Affinity Capture-MS | 27705803 | 9606 | 9606 | BIOGRID |
| EHMT2 | PSMD14 | Affinity Capture-MS | 27705803 | 9606 | 9606 | BIOGRID |
| EHMT2 | RCN2 | Affinity Capture-MS | 27705803 | 9606 | 9606 | BIOGRID |
| EHMT2 | RUVBL1 | Affinity Capture-MS | 27705803 | 9606 | 9606 | BIOGRID |
| EHMT2 | TCP1 | Affinity Capture-MS | 27705803 | 9606 | 9606 | BIOGRID |
| EHMT2 | CCT3 | Affinity Capture-MS | 27705803 | 9606 | 9606 | BIOGRID |
| EHMT2 | CCT7 | Affinity Capture-MS | 27705803 | 9606 | 9606 | BIOGRID |
| EHMT2 | TRIM28 | Affinity Capture-MS | 27705803 | 9606 | 9606 | BIOGRID |
| EHMT2 | WDR5 | Affinity Capture-MS | 27705803 | 9606 | 9606 | BIOGRID |
| EHMT2 | WIZ | Affinity Capture-MS | 27705803 | 9606 | 9606 | BIOGRID |
| EHMT2 | ZNF644 | Affinity Capture-MS | 27705803 | 9606 | 9606 | BIOGRID |
| EHMT2 | CHD4 | Affinity Capture-Western | 28486105 | 9606 | 9606 | BIOGRID |
| EHMT2 | NOS2 | Negative Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| EHMT2 | NAGK | Negative Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| EHMT2 | GPX1 | Negative Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| EHMT2 | SLC16A8 | Positive Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| EHMT2 | AURKA | Biochemical Activity | 30013191 | 9606 | 9606 | BIOGRID |
| EHMT2 | CDYL | Affinity Capture-MS | 28698370 | 9606 | 9606 | BIOGRID |
| EHMT2 | EHMT1 | Affinity Capture-MS | 28698370 | 9606 | 9606 | BIOGRID |
| EHMT2 | WIZ | Affinity Capture-MS | 28698370 | 9606 | 9606 | BIOGRID |
| EHMT2 | RPA1 | Affinity Capture-MS | 28698370 | 9606 | 9606 | BIOGRID |
| EHMT2 | RPA2 | Affinity Capture-MS | 28698370 | 9606 | 9606 | BIOGRID |
| EHMT2 | RPA1 | Affinity Capture-Western | 28698370 | 9606 | 9606 | BIOGRID |
| EHMT2 | RPA2 | Affinity Capture-Western | 28698370 | 9606 | 9606 | BIOGRID |
| EHMT2 | RPA1 | Reconstituted Complex | 28698370 | 9606 | 9606 | BIOGRID |
| EHMT2 | FOXO1 | Biochemical Activity | 30535125 | 9606 | 9606 | BIOGRID |
| EHMT2 | FOXO1 | Affinity Capture-Western | 30535125 | 9606 | 9606 | BIOGRID |
| EHMT2 | LIG1 | Biochemical Activity | 30639225 | 9606 | 9606 | BIOGRID |
| EHMT2 | RNF20 | Affinity Capture-Western | 33364200 | 9606 | 9606 | BIOGRID |
| EHMT2 | CBX1 | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| EHMT2 | MIS12 | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| EHMT2 | Ehmt1 | Affinity Capture-MS | 16702210 | 9606 | 10090 | BIOGRID |
| EHMT2 | Wiz | Affinity Capture-MS | 16702210 | 9606 | 10090 | BIOGRID |
| EHMT2 | HIST1H3C | Biochemical Activity | 25420628 | 9606 | 9913 | BIOGRID |
| EHMT2 | Lig1 | Biochemical Activity | 28803780 | 9606 | 10090 | BIOGRID |
Annotation of EHMT2
TCGA cancer survival map of EHMT2
Expression of EHMT2
Disease information of EHMT2