TcoF overview
TcoF: EIF2AK2
GeneID: 3055
Name: Interferon-induced, double-stranded RNA-activated protein kinase
Ensembl: ENSG00000055332
Species: Human
Class: class 1
Family: Others
Disease: 13
Go term: 40
Pathway: 7
Hallmark: 2
Super Enhancer:

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Enhancer:

chr2:37226950-37227720 chr2:37395210-37396470 chr2:37423660-37425630 chr2:37317010-37317820 chr2:37317860-37319050 chr2:37201450-37202400 chr2:37349810-37350700 chr2:37381920-37384050 chr2:37368070-37368690 chr2:37247020-37247790 chr2:37352200-37353290 chr2:37785400-37787750 chr2:37788090-37789830 chr2:37789960-37791990 chr2:37816550-37818390 chr2:37819050-37820040 chr2:37915310-37917690 chr2:37937560-37939780 chr2:37939870-37941220 chr2:37991860-37992210 chr2:37993150-37993900 chr2:37998270-37999710 chr2:38002090-38002730 chr2:38002750-38004320 chr2:37616460-37618560 chr2:37230830-37232770 chr2:37471120-37473190 chr2:37232900-37234190 chr2:37085490-37086750 chr2:37239680-37240980 chr2:37397600-37398570 chr2:37116140-37118190 chr2:37330070-37332280 chr2:37509760-37511850 chr2:37572000-37574290 chr2:37613870-37615640 chr2:37647880-37650290 chr2:37793260-37794890 chr2:37840860-37841910 chr2:37947610-37948640 chr2:37961880-37963320 chr2:37969160-37969920 chr2:37989290-37989860 chr2:38022320-38022920 chr2:38022970-38024790 chr2:38025170-38026290 chr2:38028880-38031120 chr2:38045770-38047230 chr2:38055020-38056070 chr2:38056180-38056390 chr2:38095110-38097230 chr2:38134360-38135320 chr2:38135910-38137290 chr2:38137990-38140360 chr2:38298450-38300050 chr2:38300380-38301480 chr2:38324560-38327060 chr2:38332810-38334780 chr2:38335940-38338140 chr2:38346240-38348430 chr2:37945160-37947030 chr2:38322130-38324470 chr2:37048070-37049240 chr2:37247980-37249720 chr2:37748960-37749570 chr2:37750490-37752810 chr2:37770930-37772740 chr2:37837740-37839030 chr2:37857650-37858890 chr2:37867860-37869020 chr2:37896420-37898560 chr2:37984250-37985040 chr2:38017420-38018090 chr2:37178240-37179690 chr2:37179790-37180410 chr2:37180740-37182710 chr2:37279190-37280640 chr2:37505130-37506880 chr2:37575980-37578400 chr2:37606580-37608110 chr2:37584660-37586720 chr2:37500020-37500670 chr2:37507680-37508190 chr2:37594550-37594770 chr2:37082500-37084990 chr2:37442100-37443280 chr2:36930020-36930360 chr2:37118580-37119180 chr2:36928030-36929730 chr2:38013000-38014830 chr2:37592140-37594370 chr2:37733430-37734600 chr2:37734760-37735970 chr2:37845030-37845930 chr2:37880840-37883090 chr2:37894030-37894770 chr2:37895470-37896190 chr2:37933740-37936180 chr2:38101140-38102450 chr2:37535570-37536510 chr2:37846360-37847480 chr2:37879250-37880760 chr2:36980680-36981580 chr2:37146240-37146760 chr2:37425820-37426840 chr2:37431890-37434360 chr2:37532900-37533460 chr2:37670830-37673280 chr2:37757040-37757500 chr2:37780390-37781640

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Promoter:

chr2:37326353-37384208

False
 ChIP-seq based regulatory details of EIF2AK2
select * from encode where Experiment_target='EIF2AK2'
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
 Downstream target genes of EIF2AK2
 Protein-protein interaction of EIF2AK2
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
EIF2AK2 STAT1 Affinity Capture-Western 9135145 9606 9606 BIOGRID
EIF2AK2 PPP1CA Affinity Capture-Western 12138106 9606 9606 BIOGRID
EIF2AK2 PRKRA Reconstituted Complex 11985496 9606 9606 BIOGRID
EIF2AK2 TP53 Affinity Capture-Western 10348343 9606 9606 BIOGRID
EIF2AK2 TP53 Reconstituted Complex 10348343 9606 9606 BIOGRID
EIF2AK2 TP53 Biochemical Activity 10348343 9606 9606 BIOGRID
EIF2AK2 ILF3 Two-hybrid 11438536 9606 9606 BIOGRID
EIF2AK2 ILF3 Reconstituted Complex 11438536 9606 9606 BIOGRID
EIF2AK2 ILF3 Affinity Capture-Western 11438536 9606 9606 BIOGRID
EIF2AK2 ILF3 Biochemical Activity 11438536 9606 9606 BIOGRID
EIF2AK2 ILF3 Biochemical Activity 10320367 9606 9606 BIOGRID
EIF2AK2 PPP2R5A Affinity Capture-Western 10866685 9606 9606 BIOGRID
EIF2AK2 ILF3 Reconstituted Complex 11438540 9606 9606 BIOGRID
EIF2AK2 ILF3 Affinity Capture-Western 11438540 9606 9606 BIOGRID
EIF2AK2 ILF3 Biochemical Activity 11438540 9606 9606 BIOGRID
EIF2AK2 ILF2 Biochemical Activity 11438540 9606 9606 BIOGRID
EIF2AK2 ILF3 Reconstituted Complex 10400669 9606 9606 BIOGRID
EIF2AK2 ILF3 Biochemical Activity 10400669 9606 9606 BIOGRID
EIF2AK2 ILF3 Two-hybrid 10400669 9606 9606 BIOGRID
EIF2AK2 EIF2AK2 Two-hybrid 7568151 9606 9606 BIOGRID
EIF2AK2 TARBP2 Two-hybrid 7568151 9606 9606 BIOGRID
EIF2AK2 EIF2AK2 Far Western 7568151 9606 9606 BIOGRID
EIF2AK2 TARBP2 Far Western 7568151 9606 9606 BIOGRID
EIF2AK2 TARBP2 Two-hybrid 11438532 9606 9606 BIOGRID
EIF2AK2 STAT1 Reconstituted Complex 11278865 9606 9606 BIOGRID
EIF2AK2 MAP3K5 Affinity Capture-Western 12473108 9606 9606 BIOGRID
EIF2AK2 PRKRA Two-hybrid 9687506 9606 9606 BIOGRID
EIF2AK2 EIF2AK2 Affinity Capture-Western 10848580 9606 9606 BIOGRID
EIF2AK2 HIST2H2AC Biochemical Activity 9447982 9606 9606 BIOGRID
EIF2AK2 PDGFRB Affinity Capture-Western 11350938 9606 9606 BIOGRID
EIF2AK2 STAT3 Affinity Capture-Western 11350938 9606 9606 BIOGRID
EIF2AK2 EIF2S1 Reconstituted Complex 19364808 9606 9606 BIOGRID
EIF2AK2 CCNA2 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 DHX9 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 DICER1 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 EDC4 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 STAU2 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 TARBP2 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 ZNF346 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 PRKRA Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 STAU1 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 CCDC124 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 CDK3 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 EBNA1BP2 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 FARSB Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 FTSJ3 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 GLTSCR2 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 IFRD1 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 NOC3L Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 PPP1CC Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 DHX30 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 EIF6 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 FARSA Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 GNL3 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 GTPBP4 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 HIST1H1C Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 HNRNPC Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 HNRNPCL1 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 KCTD17 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 LYAR Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 MOV10 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 NOP2 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 PABPC4 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 PURA Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 SSB Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 TOLLIP Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 TOP1 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 XRN2 Affinity Capture-MS 21903422 9606 9606 BIOGRID
EIF2AK2 DHX30 Reconstituted Complex 21903422 9606 9606 BIOGRID
EIF2AK2 DICER1 Reconstituted Complex 21903422 9606 9606 BIOGRID
EIF2AK2 EDC4 Reconstituted Complex 21903422 9606 9606 BIOGRID
EIF2AK2 EIF6 Reconstituted Complex 21903422 9606 9606 BIOGRID
EIF2AK2 FTSJ3 Reconstituted Complex 21903422 9606 9606 BIOGRID
EIF2AK2 MOV10 Reconstituted Complex 21903422 9606 9606 BIOGRID
EIF2AK2 STAU2 Reconstituted Complex 21903422 9606 9606 BIOGRID
EIF2AK2 TARBP2 Reconstituted Complex 21903422 9606 9606 BIOGRID
EIF2AK2 TOLLIP Reconstituted Complex 21903422 9606 9606 BIOGRID
EIF2AK2 ZNF346 Reconstituted Complex 21903422 9606 9606 BIOGRID
EIF2AK2 DHX9 Reconstituted Complex 21903422 9606 9606 BIOGRID
EIF2AK2 CHUK Affinity Capture-Western 10723127 9606 9606 BIOGRID
EIF2AK2 ATP6V1F Co-fractionation 22939629 9606 9606 BIOGRID
EIF2AK2 JAK1 Affinity Capture-Western 17290288 9606 9606 BIOGRID
EIF2AK2 TYK2 Affinity Capture-Western 17290288 9606 9606 BIOGRID
EIF2AK2 EIF2S1 Affinity Capture-Western 17290288 9606 9606 BIOGRID
EIF2AK2 TYK2 Reconstituted Complex 17290288 9606 9606 BIOGRID
EIF2AK2 IL7R Protein-RNA 23151878 9606 9606 BIOGRID
EIF2AK2 NPM1 Affinity Capture-Western 16957780 9606 9606 BIOGRID
EIF2AK2 DHX9 Affinity Capture-Western 19229320 9606 9606 BIOGRID
EIF2AK2 DHX9 Affinity Capture-MS 19229320 9606 9606 BIOGRID
EIF2AK2 EIF2A Affinity Capture-Western 19229320 9606 9606 BIOGRID
EIF2AK2 DHX9 Biochemical Activity 19229320 9606 9606 BIOGRID
EIF2AK2 EIF2AK2 Affinity Capture-Western 11447118 9606 9606 BIOGRID
EIF2AK2 IGF2BP3 Affinity Capture-MS 23455922 9606 9606 BIOGRID
EIF2AK2 PRKRA Affinity Capture-MS 23455922 9606 9606 BIOGRID
EIF2AK2 DHX30 Affinity Capture-MS 23455922 9606 9606 BIOGRID
EIF2AK2 IGF2BP2 Affinity Capture-MS 23455922 9606 9606 BIOGRID
EIF2AK2 TRAF5 Affinity Capture-Western 15121867 9606 9606 BIOGRID
EIF2AK2 TRAF6 Affinity Capture-Western 15121867 9606 9606 BIOGRID
EIF2AK2 EIF2AK2 Biochemical Activity 18082144 9606 9606 BIOGRID
EIF2AK2 EIF2S1 Biochemical Activity 21368187 9606 9606 BIOGRID
EIF2AK2 TRAF2 Affinity Capture-Western 25715336 9606 9606 BIOGRID
EIF2AK2 TRAF6 Affinity Capture-Western 25715336 9606 9606 BIOGRID
EIF2AK2 HIST1H2AB Biochemical Activity 20484669 9606 9606 BIOGRID
EIF2AK2 TP53 Affinity Capture-Western 19631745 9606 9606 BIOGRID
EIF2AK2 NPM1 Affinity Capture-Western 12882984 9606 9606 BIOGRID
EIF2AK2 NPM1 Affinity Capture-MS 12882984 9606 9606 BIOGRID
EIF2AK2 RPL6 Affinity Capture-MS 12882984 9606 9606 BIOGRID
EIF2AK2 RPLP0 Affinity Capture-MS 12882984 9606 9606 BIOGRID
EIF2AK2 RPS2 Affinity Capture-MS 12882984 9606 9606 BIOGRID
EIF2AK2 RPS3A Affinity Capture-MS 12882984 9606 9606 BIOGRID
EIF2AK2 LMNA Affinity Capture-MS 12882984 9606 9606 BIOGRID
EIF2AK2 NPM1 Reconstituted Complex 12882984 9606 9606 BIOGRID
EIF2AK2 NPM1 Biochemical Activity 12882984 9606 9606 BIOGRID
EIF2AK2 EIF2AK2 Biochemical Activity 12882984 9606 9606 BIOGRID
EIF2AK2 EIF2S1 Biochemical Activity 12882984 9606 9606 BIOGRID
EIF2AK2 EIF2S1 Reconstituted Complex 12882984 9606 9606 BIOGRID
EIF2AK2 EIF2A Biochemical Activity 29070839 9606 9606 BIOGRID
EIF2AK2 EIF2AK2 Reconstituted Complex 29070839 9606 9606 BIOGRID
EIF2AK2 PRKRA Two-hybrid 32296183 9606 9606 BIOGRID
EIF2AK2 ADARB1 Two-hybrid 32296183 9606 9606 BIOGRID
EIF2AK2 TRADD Proximity Label-MS 30021884 9606 9606 BIOGRID
EIF2AK2 YGR054W Biochemical Activity 31086188 9606 559292 BIOGRID
EIF2AK2 SUI2 Biochemical Activity 30070006 9606 559292 BIOGRID
 Annotation of EIF2AK2
 TCGA cancer survival map of EIF2AK2


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  EIF2AK2