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TcoF overview
TcoF: ERBB4
GeneID: 2274
Name: Receptor protein-tyrosine kinase
Ensembl: ENSG00000178568
Species: Human
Class: class HC
Family: Erbb2
Disease: 17
Go term: 61
Pathway: 27
Hallmark: 2
Super Enhancer:

chr2:212361810-212380384 chr2:212454937-212459175 chr2:212270240-212301258 chr2:212861418-212919389 chr2:212982701-213022080 chr2:213140558-213180469 chr2:212224073-212344054 chr2:212256585-212303722 chr2:212789528-212846598 chr2:213338442-213415262 chr2:212255257-212333582 chr2:213169755-213232113 chr2:212889582-212932838 chr2:213128448-213151511 chr2:212348202-212380676 chr2:213337276-213415386 chr2:213128471-213258121 chr2:212257526-212333619 chr2:212348317-212380733 chr2:212888576-212933368 chr2:213706253-213711784
Enhancer:

--
Promoter:

chr2:212240442-213403565

 ChIP-seq based regulatory details of ERBB4
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
 Downstream target genes of ERBB4
 Upstream regulatory details of ERBB4
 Protein-protein interaction of ERBB4
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
ERBB4 DLG3 Two-hybrid 10725395 9606 9606 BIOGRID
ERBB4 SNTB2 Two-hybrid 10725395 9606 9606 BIOGRID
ERBB4 DLG4 Two-hybrid 10725395 9606 9606 BIOGRID
ERBB4 YAP1 Two-hybrid 15023535 9606 9606 BIOGRID
ERBB4 DLG2 Two-hybrid 10725395 9606 9606 BIOGRID
ERBB4 STAT5A Affinity Capture-Western 15534001 9606 9606 BIOGRID
ERBB4 SHC1 Affinity Capture-MS 16729043 9606 9606 BIOGRID
ERBB4 STAT5A Affinity Capture-MS 16729043 9606 9606 BIOGRID
ERBB4 CRK Affinity Capture-MS 16729043 9606 9606 BIOGRID
ERBB4 GRB2 Affinity Capture-MS 16729043 9606 9606 BIOGRID
ERBB4 PTPN11 Affinity Capture-MS 16729043 9606 9606 BIOGRID
ERBB4 PIK3R2 Affinity Capture-MS 16729043 9606 9606 BIOGRID
ERBB4 NCK1 Affinity Capture-MS 16729043 9606 9606 BIOGRID
ERBB4 YAP1 Reconstituted Complex 15023535 9606 9606 BIOGRID
ERBB4 YAP1 Affinity Capture-Western 15023535 9606 9606 BIOGRID
ERBB4 DLG4 Affinity Capture-Western 10839362 9606 9606 BIOGRID
ERBB4 ERBB2 Affinity Capture-Western 10839362 9606 9606 BIOGRID
ERBB4 DLG4 Affinity Capture-Western 10725395 9606 9606 BIOGRID
ERBB4 DLG1 Affinity Capture-Western 12175853 9606 9606 BIOGRID
ERBB4 ITCH Affinity Capture-Western 18334649 9606 9606 BIOGRID
ERBB4 NEDD4 Affinity Capture-Western 19193720 9606 9606 BIOGRID
ERBB4 YAP1 Two-hybrid 12807903 9606 9606 BIOGRID
ERBB4 YAP1 Co-localization 12807903 9606 9606 BIOGRID
ERBB4 TAB2 Two-hybrid 17018285 9606 9606 BIOGRID
ERBB4 DLG4 Two-hybrid 17018285 9606 9606 BIOGRID
ERBB4 TAB2 Affinity Capture-Western 17018285 9606 9606 BIOGRID
ERBB4 NCOR1 Affinity Capture-Western 17018285 9606 9606 BIOGRID
ERBB4 PIAS3 Affinity Capture-Western 22584572 9606 9606 BIOGRID
ERBB4 PIAS4 Affinity Capture-Western 22584572 9606 9606 BIOGRID
ERBB4 STAT5A Affinity Capture-Western 22584572 9606 9606 BIOGRID
ERBB4 WWOX Affinity Capture-Western 22584572 9606 9606 BIOGRID
ERBB4 WWP1 Affinity Capture-Western 19047365 9606 9606 BIOGRID
ERBB4 TRIM28 Affinity Capture-Western 20858735 9606 9606 BIOGRID
ERBB4 MDM2 Affinity Capture-Western 20858735 9606 9606 BIOGRID
ERBB4 TP53 Affinity Capture-Western 20858735 9606 9606 BIOGRID
ERBB4 BYSL Reconstituted Complex 17360433 9606 9606 BIOGRID
ERBB4 TRO Reconstituted Complex 17360433 9606 9606 BIOGRID
ERBB4 TRO Affinity Capture-Western 17360433 9606 9606 BIOGRID
ERBB4 BYSL Affinity Capture-Western 17360433 9606 9606 BIOGRID
ERBB4 TRO Co-localization 17360433 9606 9606 BIOGRID
ERBB4 BYSL Co-localization 17360433 9606 9606 BIOGRID
ERBB4 ANKS1B Protein-peptide 16273093 9606 9606 BIOGRID
ERBB4 ANKS1A Protein-peptide 16273093 9606 9606 BIOGRID
ERBB4 GRB2 Affinity Capture-Western 25140053 9606 9606 BIOGRID
ERBB4 CBL Affinity Capture-Western 25140053 9606 9606 BIOGRID
ERBB4 ERBB4 Biochemical Activity 20943952 9606 9606 BIOGRID
ERBB4 TFAP2C Reconstituted Complex 20943952 9606 9606 BIOGRID
ERBB4 WWOX Reconstituted Complex 20943952 9606 9606 BIOGRID
ERBB4 DLG4 Affinity Capture-Western 16767099 9606 9606 BIOGRID
ERBB4 PTPN6 Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 PTPN7 Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 PTPN11 Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 PTPN12 Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 PTPRR Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 PTPRH Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 PTPRT Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 PPM1A Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 PPM1B Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 PPM1F Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 ILKAP Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 TAB1 Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 PTPN20B Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 DUSP6 Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 DUSP10 Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 DUSP16 Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 DUSP14 Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 DUSP18 Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 DUSP19 Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 DUSP21 Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 STYX Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 PTPDC1 Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 MTMR2 Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 MTMR6 Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 MTMR9 Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 CDC25C Two-hybrid 28065597 9606 9606 BIOGRID
ERBB4 NRG2 Reconstituted Complex 15358134 9606 9606 BIOGRID
ERBB4 ESR1 Affinity Capture-Western 19439407 9606 9606 BIOGRID
ERBB4 VANGL1 Affinity Capture-Western 27648936 9606 9606 BIOGRID
ERBB4 RNF41 Affinity Capture-Western 27648936 9606 9606 BIOGRID
ERBB4 XPO1 Affinity Capture-Western 28974580 9606 9606 BIOGRID
ERBB4 XPO1 Co-localization 28974580 9606 9606 BIOGRID
ERBB4 PTPN21 Affinity Capture-Western 25681686 9606 9606 BIOGRID
ERBB4 FYN Two-hybrid 17460065 9606 9606 BIOGRID
ERBB4 FYN Affinity Capture-Western 17460065 9606 9606 BIOGRID
ERBB4 NTRK2 Affinity Capture-Western 25052836 9606 9606 BIOGRID
ERBB4 NTRK2 FRET 25052836 9606 9606 BIOGRID
ERBB4 DLG4 Co-fractionation 12716924 9606 9606 BIOGRID
ERBB4 WWOX Affinity Capture-Western 16061658 9606 9606 BIOGRID
ERBB4 YAP1 Affinity Capture-Western 16061658 9606 9606 BIOGRID
ERBB4 ERBB4 Two-hybrid 25315821 9606 9606 BIOGRID
ERBB4 MUC4 Two-hybrid 25315821 9606 9606 BIOGRID
ERBB4 GRM2 Positive Genetic 28319085 9606 9606 BIOGRID
ERBB4 ERBB4 Reconstituted Complex 8816440 9606 9606 BIOGRID
ERBB4 ERBB2 Reconstituted Complex 8816440 9606 9606 BIOGRID
ERBB4 ERBB4 Biochemical Activity 16170367 9606 9606 BIOGRID
ERBB4 ERBB4 Affinity Capture-Western 16170367 9606 9606 BIOGRID
ERBB4 ERBB4 Reconstituted Complex 16170367 9606 9606 BIOGRID
ERBB4 C10orf35 Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 C14orf1 Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 TMEM230 Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 SMIM20 Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 GABARAPL2 Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 HDAC6 Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 CFL1 Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 ALDOA Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 IRF2BP2 Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 LRRC7 Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 PIN4 Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 PRRG4 Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 RTN4 Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 S100A11 Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 SELK Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 SNAP91 Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 SYNM Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 TMEM134 Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 TMEM14A Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 TXN Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 ZNF532 Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 TMA7 Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 FKBP1A Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 TVP23B Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 PRDX5 Two-hybrid 31980649 9606 9606 BIOGRID
ERBB4 ABL1 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 ABL2 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 BCAR3 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 BLK Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 CRK Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 FES Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 FGR Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 GRAP2 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 GRB10 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 GRB2 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 GRB7 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 HCK Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 HSH2D Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 INPPL1 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 ITK Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 LCK Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 LCP2 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 LYN Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 MATK Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 NCK1 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 NCK2 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 PIK3R1 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 PIK3R2 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 PIK3R3 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 PLCG1 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 PLCG2 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 PTK6 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 PTPN11 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 PTPN6 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 RASA1 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SH2B1 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SH2B2 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SH2B3 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SH2D1A Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SH2D1B Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SH2D2A Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SH2D3C Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SH3BP2 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SHB Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SHC1 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SHC2 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SHC3 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SHC4 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SHD Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SLA Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SLA2 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SOCS1 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SOCS2 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SOCS3 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SOCS5 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SOCS6 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SRC Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 STAP1 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 SYK Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 TEC Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 TENC1 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 TNS1 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 TNS3 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 TNS4 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 TXK Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 VAV1 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 VAV2 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 VAV3 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 YES1 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 ZAP70 Reconstituted Complex 22973453 9606 9606 BIOGRID
ERBB4 cdh11 Affinity Capture-Western 29190819 9606 8355 BIOGRID
 Annotation of ERBB4
 TCGA cancer survival map of ERBB4


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Expression of  ERBB4
 Disease information of  ERBB4