TcoF overview
TcoF: ERCC3
GeneID: 64855
Name: General transcription and DNA repair factor IIH helicase subunit XPB
Ensembl: ENSG00000163161
Species: Human
Class: NA
Family: Others
Disease: 21
Go term: 48
Pathway: 30
Hallmark: 2
Super Enhancer:

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Enhancer:

chr2:127811020-127811480 chr2:128051300-128051620 chr2:127951440-127952910 chr2:128403820-128405610 chr2:128068530-128069310 chr2:127806210-127807990 chr2:127818210-127819690 chr2:127825830-127826490 chr2:128050420-128051080 chr2:128179030-128180490 chr2:128180510-128180600 chr2:128180750-128180840 chr2:128180980-128181110 chr2:128321840-128322800 chr2:128387400-128388350 chr2:128388480-128388780 chr2:128390940-128391750 chr2:128394200-128394360 chr2:128394490-128394890 chr2:128395300-128395990 chr2:128431320-128432580 chr2:128452510-128453590 chr2:128391860-128392170 chr2:128397000-128397640 chr2:128397720-128397840 chr2:128397890-128398440 chr2:127796510-127798120 chr2:127976490-127978180 chr2:127950870-127951360 chr2:128011790-128013600 chr2:128393480-128393780 chr2:127836280-127836860 chr2:127836970-127839250 chr2:128265060-128267320 chr2:127844260-127846040 chr2:128033800-128036230 chr2:128334280-128335700 chr2:128147150-128148180 chr2:128281370-128283750 chr2:128309090-128311080 chr2:128081820-128083300 chr2:128177590-128178850 chr2:127769700-127770980 chr2:127772210-127772550 chr2:128267530-128268390 chr2:128331770-128334160 chr2:127733570-127735250 chr2:127878200-127880450 chr2:127905890-127907940 chr2:127930020-127932010 chr2:127988740-127989400 chr2:128164690-128167170 chr2:128176070-128177490 chr2:128255950-128256560 chr2:128299570-128301270 chr2:128325120-128327360 chr2:128474840-128476730 chr2:127821220-127821500 chr2:127982410-127983700 chr2:127983800-127984970 chr2:128479560-128480160 chr2:127811590-127813990 chr2:128158060-128160430 chr2:128293410-128295810 chr2:128393900-128394110 chr2:128490560-128492950 chr2:128380950-128381660 chr2:128412470-128414970 chr2:127900680-127902520 chr2:127903120-127903600 chr2:128243460-128243610 chr2:128244240-128244500 chr2:128392260-128392690 chr2:128410830-128411990 chr2:128477930-128479400 chr2:127753200-127755380 chr2:127762520-127764480 chr2:128315300-128317270 chr2:128220770-128222660 chr2:128236160-128238380 chr2:128270080-128270400 chr2:127808100-127808370 chr2:127808490-127808720 chr2:127808820-127809830 chr2:127809940-127810990 chr2:127815180-127816580 chr2:127817800-127818170 chr2:127819770-127821140 chr2:127826610-127827570 chr2:127827670-127828120 chr2:127904140-127905300

Promoter:

chr2:128014866-128051752

 ChIP-seq based regulatory details of ERCC3
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
TcoF_00_30824 ERCC3 cell line HT-1080 GSM1092544 Bone ChIP-Atlas
 Downstream target genes of ERCC3
 Protein-protein interaction of ERCC3
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
ERCC3 ERCC2 Co-purification 15220921 9606 9606 BIOGRID
ERCC3 GTF2H4 Co-purification 15220921 9606 9606 BIOGRID
ERCC3 GTF2H1 Co-purification 15220921 9606 9606 BIOGRID
ERCC3 GTF2H2 Co-purification 15220921 9606 9606 BIOGRID
ERCC3 GTF2H3 Co-purification 15220921 9606 9606 BIOGRID
ERCC3 CDK7 Co-purification 15220921 9606 9606 BIOGRID
ERCC3 GTF2H5 Co-purification 15220921 9606 9606 BIOGRID
ERCC3 CCNH Co-purification 15220921 9606 9606 BIOGRID
ERCC3 MNAT1 Co-purification 15220921 9606 9606 BIOGRID
ERCC3 GTF2E1 Reconstituted Complex 7926747 9606 9606 BIOGRID
ERCC3 GTF2E2 Reconstituted Complex 7926747 9606 9606 BIOGRID
ERCC3 GTF2H1 Affinity Capture-Western 9118947 9606 9606 BIOGRID
ERCC3 GTF2H2 Affinity Capture-Western 9118947 9606 9606 BIOGRID
ERCC3 GTF2H3 Affinity Capture-Western 9118947 9606 9606 BIOGRID
ERCC3 GTF2H4 Affinity Capture-Western 9118947 9606 9606 BIOGRID
ERCC3 ERCC2 Affinity Capture-Western 9118947 9606 9606 BIOGRID
ERCC3 PSMC5 Affinity Capture-Western 9173976 9606 9606 BIOGRID
ERCC3 PSMC5 Reconstituted Complex 9173976 9606 9606 BIOGRID
ERCC3 ERCC2 Affinity Capture-Western 8652557 9606 9606 BIOGRID
ERCC3 CDK7 Affinity Capture-MS 17643375 9606 9606 BIOGRID
ERCC3 GTF2H1 Affinity Capture-MS 17643375 9606 9606 BIOGRID
ERCC3 GTF2H3 Affinity Capture-MS 17643375 9606 9606 BIOGRID
ERCC3 GTF2H2 Affinity Capture-MS 17643375 9606 9606 BIOGRID
ERCC3 CCNH Affinity Capture-MS 17643375 9606 9606 BIOGRID
ERCC3 ERCC5 Affinity Capture-MS 17643375 9606 9606 BIOGRID
ERCC3 BCR Affinity Capture-MS 17643375 9606 9606 BIOGRID
ERCC3 GCN1L1 Affinity Capture-MS 17643375 9606 9606 BIOGRID
ERCC3 MNAT1 Affinity Capture-MS 17643375 9606 9606 BIOGRID
ERCC3 ZSCAN1 Two-hybrid 20211142 9606 9606 BIOGRID
ERCC3 GTF2H1 Affinity Capture-Western 8692842 9606 9606 BIOGRID
ERCC3 CCNH Affinity Capture-Western 8692842 9606 9606 BIOGRID
ERCC3 MNAT1 Affinity Capture-Western 8692842 9606 9606 BIOGRID
ERCC3 GTF2H2 Co-purification 8194529 9606 9606 BIOGRID
ERCC3 GTF2H3 Co-purification 8194529 9606 9606 BIOGRID
ERCC3 GTF2H1 Co-fractionation 22939629 9606 9606 BIOGRID
ERCC3 GTF2H3 Co-fractionation 22939629 9606 9606 BIOGRID
ERCC3 GTF2H4 Co-fractionation 22939629 9606 9606 BIOGRID
ERCC3 SIX5 Co-fractionation 22939629 9606 9606 BIOGRID
ERCC3 TP53 Reconstituted Complex 12379483 9606 9606 BIOGRID
ERCC3 MMS19 Affinity Capture-Western 11071939 9606 9606 BIOGRID
ERCC3 RAD52 Affinity Capture-Western 12372413 9606 9606 BIOGRID
ERCC3 UVSSA Affinity Capture-Western 22902626 9606 9606 BIOGRID
ERCC3 ERCC2 Affinity Capture-Western 22678362 9606 9606 BIOGRID
ERCC3 KPNA3 Two-hybrid 21988832 9606 9606 BIOGRID
ERCC3 CEP70 Two-hybrid 25416956 9606 9606 BIOGRID
ERCC3 BCR Reconstituted Complex 10403766 9606 9606 BIOGRID
ERCC3 MCF2 Reconstituted Complex 10403766 9606 9606 BIOGRID
ERCC3 CDC42 Reconstituted Complex 10403766 9606 9606 BIOGRID
ERCC3 BCR Affinity Capture-Western 10403766 9606 9606 BIOGRID
ERCC3 GTF2H1 Affinity Capture-Western 10403766 9606 9606 BIOGRID
ERCC3 GTF2H1 Co-fractionation 26344197 9606 9606 BIOGRID
ERCC3 GTF2H2C Co-fractionation 26344197 9606 9606 BIOGRID
ERCC3 GTF2H2 Co-fractionation 26344197 9606 9606 BIOGRID
ERCC3 GTF2H2C_2 Co-fractionation 26344197 9606 9606 BIOGRID
ERCC3 GTF2H3 Co-fractionation 26344197 9606 9606 BIOGRID
ERCC3 GTF2H4 Co-fractionation 26344197 9606 9606 BIOGRID
ERCC3 GOLGA2 Two-hybrid 21516116 9606 9606 BIOGRID
ERCC3 UBXN7 Affinity Capture-Western 26389662 9606 9606 BIOGRID
ERCC3 GTF2H3 Affinity Capture-MS 28514442 9606 9606 BIOGRID
ERCC3 GTF2H5 Affinity Capture-MS 28514442 9606 9606 BIOGRID
ERCC3 GTF2H1 Affinity Capture-MS 28514442 9606 9606 BIOGRID
ERCC3 ERCC5 Affinity Capture-MS 28514442 9606 9606 BIOGRID
ERCC3 GTF2H4 Affinity Capture-MS 28514442 9606 9606 BIOGRID
ERCC3 CCNH Affinity Capture-MS 28514442 9606 9606 BIOGRID
ERCC3 ZNF143 Affinity Capture-MS 28514442 9606 9606 BIOGRID
ERCC3 BCR Affinity Capture-MS 28514442 9606 9606 BIOGRID
ERCC3 GTF2H2 Affinity Capture-MS 28514442 9606 9606 BIOGRID
ERCC3 USP7 Affinity Capture-MS 28514442 9606 9606 BIOGRID
ERCC3 COX11 Affinity Capture-MS 28514442 9606 9606 BIOGRID
ERCC3 CDK7 Affinity Capture-MS 28514442 9606 9606 BIOGRID
ERCC3 MNAT1 Affinity Capture-MS 28514442 9606 9606 BIOGRID
ERCC3 LRRC41 Affinity Capture-MS 28514442 9606 9606 BIOGRID
ERCC3 ERCC2 Affinity Capture-Western 26340423 9606 9606 BIOGRID
ERCC3 GTF2H1 Affinity Capture-Western 26340423 9606 9606 BIOGRID
ERCC3 GTF2H4 Affinity Capture-Western 26340423 9606 9606 BIOGRID
ERCC3 GTF2H2 Affinity Capture-Western 26340423 9606 9606 BIOGRID
ERCC3 CDK7 Affinity Capture-Western 26340423 9606 9606 BIOGRID
ERCC3 CCNH Affinity Capture-Western 26340423 9606 9606 BIOGRID
ERCC3 GTF2H3 Affinity Capture-Western 26340423 9606 9606 BIOGRID
ERCC3 MNAT1 Affinity Capture-Western 26340423 9606 9606 BIOGRID
ERCC3 GTF2H5 Reconstituted Complex 26340423 9606 9606 BIOGRID
ERCC3 MNAT1 Reconstituted Complex 26340423 9606 9606 BIOGRID
ERCC3 GTF2H2 Reconstituted Complex 26340423 9606 9606 BIOGRID
ERCC3 ERCC2 Reconstituted Complex 26340423 9606 9606 BIOGRID
ERCC3 SPTA1 Affinity Capture-Western 16889989 9606 9606 BIOGRID
ERCC3 MAGED1 Two-hybrid 32296183 9606 9606 BIOGRID
ERCC3 TRIM27 Two-hybrid 32296183 9606 9606 BIOGRID
ERCC3 GTF2H1 Affinity Capture-MS 24981860 9606 9606 BIOGRID
ERCC3 GTF2H4 Affinity Capture-MS 24981860 9606 9606 BIOGRID
ERCC3 PRDM11 Affinity Capture-MS 24981860 9606 9606 BIOGRID
ERCC3 GTF2F1 Affinity Capture-MS 24981860 9606 9606 BIOGRID
ERCC3 GTF2H2C Affinity Capture-MS 24981860 9606 9606 BIOGRID
ERCC3 tat Affinity Capture-Western 9334327 9606 11676 BIOGRID
 Annotation of ERCC3
 TCGA cancer survival map of ERCC3


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  ERCC3