TcoF overview
TcoF: HDAC8
GeneID: 3006
Name: Histone deacetylase
Ensembl: ENSG00000147099
Species: Human
Class: class 2
Family: Histone deacetylase
Disease: 6
Go term: 23
Pathway: 9
Hallmark: 3
Super Enhancer:

chrX:71838597-71855686

Enhancer:

chrX:71791950-71792500 chrX:71839160-71840570 chrX:71840750-71842950 chrX:71896000-71897390 chrX:71932780-71933650 chrX:72017940-72020010 chrX:72130740-72132740 chrX:71925090-71926090 chrX:71401680-71403960 chrX:71420970-71423200 chrX:71601440-71602410 chrX:71611740-71613440 chrX:71698730-71699140 chrX:71699280-71699760 chrX:71457500-71458690 chrX:71476940-71479160 chrX:71483820-71486270 chrX:71490030-71490810 chrX:71491080-71492450 chrX:71773390-71775400 chrX:71466790-71468100 chrX:72052140-72053620 chrX:72094790-72095100 chrX:72095170-72095460 chrX:71804150-71804480 chrX:71745920-71747950 chrX:71215990-71217750 chrX:71613740-71615630 chrX:71522780-71525150 chrX:71760200-71760600

Promoter:

chrX:71549366-71792951

 ChIP-seq based regulatory details of HDAC8
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
TcoF_00_10059 HDAC8 cell line K562 - Bone Marrow ENCODE
TcoF_00_10109 HDAC8 cell line K562 - Bone Marrow ENCODE
TcoF_00_40531 HDAC8 cell line K-562 - Bone Marrow ReMap
TcoF_00_20706 HDAC8 cell line K562 - Bone Marrow Cistrome
TcoF_00_20065 HDAC8 cell line K562 GSM777640 Bone Marrow Cistrome
TcoF_00_40412 HDAC8 cell line K-562 GSM777640 Bone Marrow ReMap
 Downstream target genes of HDAC8
 Protein-protein interaction of HDAC8
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
HDAC8 RUNX1T1 Affinity Capture-Western 11533236 9606 9606 BIOGRID
HDAC8 CBFA2T3 Affinity Capture-Western 11533236 9606 9606 BIOGRID
HDAC8 CREB1 Affinity Capture-Western 19070599 9606 9606 BIOGRID
HDAC8 PPP1CC Affinity Capture-Western 19070599 9606 9606 BIOGRID
HDAC8 ESRRA Biochemical Activity 20484414 9606 9606 BIOGRID
HDAC8 HIST1H3A Biochemical Activity 10926844 9606 9606 BIOGRID
HDAC8 HIST1H4A Biochemical Activity 10926844 9606 9606 BIOGRID
HDAC8 HIST3H3 Affinity Capture-Western 21499270 9606 9606 BIOGRID
HDAC8 HIST4H4 Affinity Capture-Western 21499270 9606 9606 BIOGRID
HDAC8 HSPA4 Affinity Capture-Western 16809764 9606 9606 BIOGRID
HDAC8 HSP90AA1 Affinity Capture-Western 16809764 9606 9606 BIOGRID
HDAC8 STAG2 Affinity Capture-MS 23752268 9606 9606 BIOGRID
HDAC8 CHCHD3 Affinity Capture-MS 23752268 9606 9606 BIOGRID
HDAC8 CPNE3 Affinity Capture-MS 23752268 9606 9606 BIOGRID
HDAC8 ADD3 Affinity Capture-MS 23752268 9606 9606 BIOGRID
HDAC8 MME Affinity Capture-MS 23752268 9606 9606 BIOGRID
HDAC8 NUP98 Affinity Capture-MS 23752268 9606 9606 BIOGRID
HDAC8 MDM1 Affinity Capture-MS 23752268 9606 9606 BIOGRID
HDAC8 SEC16A Affinity Capture-MS 23752268 9606 9606 BIOGRID
HDAC8 CROCC Affinity Capture-MS 23752268 9606 9606 BIOGRID
HDAC8 SMC1A Affinity Capture-MS 23752268 9606 9606 BIOGRID
HDAC8 SMC3 Affinity Capture-MS 23752268 9606 9606 BIOGRID
HDAC8 SVIL Affinity Capture-MS 23752268 9606 9606 BIOGRID
HDAC8 TPM3 Affinity Capture-MS 23752268 9606 9606 BIOGRID
HDAC8 TPM4 Affinity Capture-MS 23752268 9606 9606 BIOGRID
HDAC8 ZSCAN2 Affinity Capture-MS 23752268 9606 9606 BIOGRID
HDAC8 VPRBP Affinity Capture-Western 26679995 9606 9606 BIOGRID
HDAC8 DDB1 Affinity Capture-Western 26679995 9606 9606 BIOGRID
HDAC8 TSC2 Negative Genetic 28319085 9606 9606 BIOGRID
HDAC8 TSC1 Negative Genetic 28319085 9606 9606 BIOGRID
HDAC8 TRAPPC11 Negative Genetic 28319085 9606 9606 BIOGRID
HDAC8 IGF2BP1 Negative Genetic 28319085 9606 9606 BIOGRID
HDAC8 SLC30A5 Negative Genetic 28319085 9606 9606 BIOGRID
HDAC8 TRAPPC2L Negative Genetic 28319085 9606 9606 BIOGRID
HDAC8 NPRL3 Negative Genetic 28319085 9606 9606 BIOGRID
HDAC8 VPS45 Negative Genetic 28319085 9606 9606 BIOGRID
HDAC8 RABGEF1 Negative Genetic 28319085 9606 9606 BIOGRID
HDAC8 TRAPPC12 Positive Genetic 28319085 9606 9606 BIOGRID
HDAC8 RAB1B Positive Genetic 28319085 9606 9606 BIOGRID
HDAC8 TBL1XR1 Positive Genetic 28319085 9606 9606 BIOGRID
HDAC8 SEC23B Positive Genetic 28319085 9606 9606 BIOGRID
HDAC8 VPS53 Positive Genetic 28319085 9606 9606 BIOGRID
HDAC8 SEC31A Positive Genetic 28319085 9606 9606 BIOGRID
HDAC8 TRAPPC5 Positive Genetic 28319085 9606 9606 BIOGRID
HDAC8 UBE2M Positive Genetic 28319085 9606 9606 BIOGRID
HDAC8 MOGS Positive Genetic 28319085 9606 9606 BIOGRID
 Annotation of HDAC8
 TCGA cancer survival map of HDAC8


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  HDAC8