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TcoF overview
TcoF: INSR
GeneID: 5606
Name: Insulin receptor
Ensembl: ENSG00000171105
Species: Human
Class: class 1
Family: Others
Disease: 63
Go term: 83
Pathway: 34
Hallmark: --
Super Enhancer:

chr19:7308434-7325670 chr19:7179031-7263370 chr19:7179782-7260572 chr19:7196949-7214445 chr19:7177783-7269110 chr19:7196767-7225403 chr19:7178219-7244541 chr19:7179003-7225423 chr19:7195806-7267235 chr19:7176724-7225396 chr19:7196802-7214785 chr19:7242250-7276619 chr19:7178157-7252482 chr19:7176686-7252431 chr19:7124630-7153004 chr19:7124623-7152992 chr19:7176729-7209071 chr19:7163399-7199077 chr19:7270399-7295880
Enhancer:

chr19:7587670-7589840 chr19:7601160-7601330 chr19:7670370-7671150 chr19:7292080-7293800 chr19:7581140-7582500 chr19:7661040-7663120 chr19:7287560-7289370 chr19:7272480-7273720 chr19:7506650-7506790 chr19:7516150-7517510 chr19:7532890-7533710 chr19:7534920-7535010 chr19:7535200-7535420 chr19:7570510-7570840 chr19:7571050-7571940 chr19:7572030-7573090 chr19:7615990-7616240 chr19:7619960-7620130 chr19:7651540-7654030 chr19:7745940-7747120 chr19:7828360-7830070 chr19:7853340-7853680 chr19:7887980-7890160 chr19:7916660-7917970 chr19:7920960-7921970 chr19:7922010-7923070 chr19:7923220-7925440 chr19:7925580-7926760 chr19:7926900-7927000 chr19:7927160-7927270 chr19:7928170-7928300 chr19:7934430-7934600 chr19:7938580-7939170 chr19:7968950-7970690 chr19:7616320-7618750 chr19:7069780-7070570 chr19:7134320-7136490 chr19:7145530-7145950 chr19:7230150-7231840 chr19:7242220-7243430 chr19:7264670-7266970 chr19:7158520-7160560 chr19:6361780-6361870 chr19:6373040-6374210 chr19:7546790-7546910 chr19:7547100-7549460 chr19:6969680-6971000 chr19:7152940-7153760 chr19:7552300-7553830 chr19:7210820-7212610 chr19:7256540-7258870 chr19:7250540-7251390 chr19:7251540-7251890 chr19:7267960-7269340 chr19:7271600-7272170 chr19:7233280-7233500

Promoter:

chr19:7112266-7294425

 ChIP-seq based regulatory details of INSR
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
 Downstream target genes of INSR
 Upstream regulatory details of INSR
 Protein-protein interaction of INSR
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
INSR IRS1 Two-hybrid 11606564 9606 9606 BIOGRID
INSR FRS2 Biochemical Activity 10650943 9606 9606 BIOGRID
INSR SOCS3 Affinity Capture-Western 12560330 9606 9606 BIOGRID
INSR IRS2 Two-hybrid 8626379 9606 9606 BIOGRID
INSR IRS1 Two-hybrid 8626379 9606 9606 BIOGRID
INSR AHSG Reconstituted Complex 7906861 9606 9606 BIOGRID
INSR KHDRBS1 Affinity Capture-Western 11604231 9606 9606 BIOGRID
INSR PTPN11 Reconstituted Complex 8135823 9606 9606 BIOGRID
INSR GRB10 Two-hybrid 8621530 9606 9606 BIOGRID
INSR ENPP1 Affinity Capture-Western 10615944 9606 9606 BIOGRID
INSR ENPP1 Reconstituted Complex 10615944 9606 9606 BIOGRID
INSR GRB10 Two-hybrid 7479769 9606 9606 BIOGRID
INSR CAV1 Affinity Capture-Western 10598578 9606 9606 BIOGRID
INSR GRB2 Affinity Capture-Western 9083103 9606 9606 BIOGRID
INSR PRKCD Affinity Capture-Western 11266508 9606 9606 BIOGRID
INSR VAV3 Affinity Capture-Western 11094073 9606 9606 BIOGRID
INSR INSRR Affinity Capture-Western 8916919 9606 9606 BIOGRID
INSR SH2B1 Affinity Capture-Western 9742218 9606 9606 BIOGRID
INSR SH2B1 Two-hybrid 9742218 9606 9606 BIOGRID
INSR GRB10 Two-hybrid 9506989 9606 9606 BIOGRID
INSR INPPL1 Affinity Capture-Western 12504111 9606 9606 BIOGRID
INSR RASA1 Affinity Capture-Western 1331107 9606 9606 BIOGRID
INSR JAK2 Affinity Capture-Western 8912646 9606 9606 BIOGRID
INSR PTPN11 Affinity Capture-Western 7493946 9606 9606 BIOGRID
INSR GRB7 Two-hybrid 10803466 9606 9606 BIOGRID
INSR SHC1 Two-hybrid 10803466 9606 9606 BIOGRID
INSR SYNCRIP Biochemical Activity 11994298 9606 9606 BIOGRID
INSR GRB14 Affinity Capture-Western 11726652 9606 9606 BIOGRID
INSR SORBS1 Affinity Capture-Western 11374898 9606 9606 BIOGRID
INSR SH2B1 Two-hybrid 10594240 9606 9606 BIOGRID
INSR INPPL1 Affinity Capture-Western 17620296 9606 9606 BIOGRID
INSR SH2B2 Affinity Capture-Western 17620296 9606 9606 BIOGRID
INSR SH2B2 Two-hybrid 15031295 9606 9606 BIOGRID
INSR SOCS1 Affinity Capture-Western 11342531 9606 9606 BIOGRID
INSR SOCS6 Affinity Capture-Western 11342531 9606 9606 BIOGRID
INSR SOCS3 Affinity Capture-Western 15514089 9606 9606 BIOGRID
INSR PLCG1 Protein-peptide 22974441 9606 9606 BIOGRID
INSR IRS1 Biochemical Activity 11781100 9606 9606 BIOGRID
INSR STAT5A Affinity Capture-Western 12456798 9606 9606 BIOGRID
INSR STAT5B Affinity Capture-Western 12456798 9606 9606 BIOGRID
INSR JAK1 Affinity Capture-Western 12456798 9606 9606 BIOGRID
INSR JAK2 Affinity Capture-Western 12456798 9606 9606 BIOGRID
INSR DOK1 Biochemical Activity 11551902 9606 9606 BIOGRID
INSR IRF7 Two-hybrid 21988832 9606 9606 BIOGRID
INSR TEAD1 Two-hybrid 21988832 9606 9606 BIOGRID
INSR ARRB2 Affinity Capture-Western 19122674 9606 9606 BIOGRID
INSR KRT31 Two-hybrid 25416956 9606 9606 BIOGRID
INSR SQSTM1 Biochemical Activity 9564850 9606 9606 BIOGRID
INSR ATIC Affinity Capture-Western 25687571 9606 9606 BIOGRID
INSR PTPLAD1 Affinity Capture-Western 25687571 9606 9606 BIOGRID
INSR PRKAA1 Affinity Capture-Western 25687571 9606 9606 BIOGRID
INSR PRKAA2 Affinity Capture-Western 25687571 9606 9606 BIOGRID
INSR KIF5A Affinity Capture-Western 25687571 9606 9606 BIOGRID
INSR MARCH1 Affinity Capture-Western 27577745 9606 9606 BIOGRID
INSR PPM1A Affinity Capture-Western 28065597 9606 9606 BIOGRID
INSR PPM1F Affinity Capture-Western 28065597 9606 9606 BIOGRID
INSR PTPRR Affinity Capture-Western 28065597 9606 9606 BIOGRID
INSR DUSP18 Affinity Capture-Western 28065597 9606 9606 BIOGRID
INSR MPZL2 Affinity Capture-Western 28065597 9606 9606 BIOGRID
INSR SSH1 Affinity Capture-Western 28065597 9606 9606 BIOGRID
INSR PTPRR Two-hybrid 28065597 9606 9606 BIOGRID
INSR DUSP18 Two-hybrid 28065597 9606 9606 BIOGRID
INSR DUSP19 Two-hybrid 28065597 9606 9606 BIOGRID
INSR STYX Two-hybrid 28065597 9606 9606 BIOGRID
INSR INSR Reconstituted Complex 2033070 9606 9606 BIOGRID
INSR INSR Biochemical Activity 2033070 9606 9606 BIOGRID
INSR ACP1 Affinity Capture-Western 9299573 9606 9606 BIOGRID
INSR IRS1 Affinity Capture-Western 25667086 9606 9606 BIOGRID
INSR GNB2L1 Affinity Capture-Western 11964397 9606 9606 BIOGRID
INSR GRB14 FRET 16934761 9606 9606 BIOGRID
INSR GRB14 Affinity Capture-Western 16934761 9606 9606 BIOGRID
INSR CCDC88A Affinity Capture-Western 25187647 9606 9606 BIOGRID
INSR INSR Co-crystal Structure 16271887 9606 9606 BIOGRID
INSR PIK3R1 Affinity Capture-Western 7659087 9606 9606 BIOGRID
INSR PIK3R1 Reconstituted Complex 1334490 9606 9606 BIOGRID
INSR TRIM72 Reconstituted Complex 30586741 9606 9606 BIOGRID
INSR INSR Reconstituted Complex 29512653 9606 9606 BIOGRID
INSR INSR Co-crystal Structure 29512653 9606 9606 BIOGRID
INSR Grb14 Affinity Capture-Western 9748281 9606 10116 BIOGRID
INSR Calmodulin Biochemical Activity 8639568 9606 10029 BIOGRID
INSR Socs1 Affinity Capture-Western 11342531 9606 10116 BIOGRID
INSR Socs6 Affinity Capture-Western 11342531 9606 10116 BIOGRID
INSR Irs1 Biochemical Activity 11342531 9606 10116 BIOGRID
INSR Stat5b Biochemical Activity 12456798 9606 10090 BIOGRID
INSR Grb2 Affinity Capture-Western 7953556 9606 10116 BIOGRID
INSR Hgf Affinity Capture-Western 7953556 9606 10116 BIOGRID
INSR Cav2 Biochemical Activity 25667086 9606 10116 BIOGRID
INSR Cav2 Affinity Capture-Western 25667086 9606 10116 BIOGRID
 Annotation of INSR
 TCGA cancer survival map of INSR


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Expression of  INSR
 Disease information of  INSR