TcoF overview
| TcoF: | IRAK1 | |
| GeneID: | 2648 | |
| Name: | Interleukin-1 receptor-associated kinase 1 | |
| Ensembl: | ENSG00000184216 | |
| Species: | Human | |
| Class: | class HC | |
| Family: | Others | |
| Disease: | 13 | |
| Go term: | 51 | |
| Pathway: | 42 | |
| Hallmark: | 2 | |
| Super Enhancer: |
chrX:153267161-153285318 chrX:153267067-153281444 chrX:153266568-153289261 chrX:153266417-153288118 |
|
| Enhancer: |
chrX:153031780-153032320 chrX:153277370-153277970 chrX:153278130-153278490 chrX:152734720-152735900 chrX:153199930-153200330 chrX:153284530-153284640 chrX:153198030-153199390 chrX:153199460-153199820 chrX:153218410-153219050 chrX:153278880-153279490 chrX:153209610-153209760 chrX:153209870-153210030 chrX:153579410-153579940 chrX:153580060-153580250 chrX:153582850-153582980 chrX:153583080-153583190 chrX:153174620-153174890 chrX:153186610-153186810 chrX:153186980-153187050 chrX:153284240-153284420 chrX:153284780-153284880 chrX:153285050-153285120 chrX:153031040-153031610 chrX:153081900-153083390 chrX:153138150-153138680 chrX:152957010-152957420 chrX:153283570-153283740 chrX:153283810-153284040 chrX:153029760-153030920 chrX:153219220-153219510 chrX:153282520-153283450 chrX:153266310-153268770 chrX:153272380-153274580 chrX:153268920-153270280 chrX:153207480-153207740 chrX:153361460-153363060 chrX:152955060-152955820 chrX:152955960-152956750 chrX:152957560-152958490 chrX:152958630-152958710 chrX:152958820-152958910 chrX:153279730-153281480 chrX:153281550-153281880 chrX:153762710-153763380 chrX:153176640-153178150 chrX:153311110-153313600 chrX:153595220-153595760 chrX:153608160-153608300 chrX:153608380-153608590 chrX:153608730-153609110 chrX:153665650-153666860 chrX:153672690-153673670 chrX:153686770-153688490 chrX:153706400-153706620 chrX:153706750-153707060 chrX:153714320-153714560 chrX:153733520-153734480 chrX:153742140-153744080 chrX:153304890-153306670 chrX:153714670-153714870 chrX:153306850-153308010 chrX:153308510-153309140 chrX:153310250-153310920 chrX:153535420-153537690 chrX:153553770-153555930 chrX:153556030-153556180 chrX:153569200-153571400 chrX:152892460-152893450 chrX:153186260-153186540 chrX:152751170-152751920 chrX:152752120-152752600 chrX:152752610-152754920 chrX:152786060-152786980 chrX:152959040-152959350 chrX:152959720-152959790 chrX:152959900-152959980 chrX:152960340-152960520 chrX:152963520-152965940 chrX:152966430-152967460 chrX:152967560-152968380 chrX:152968510-152969410 chrX:153008800-153008940 chrX:153046600-153046670 chrX:153046800-153046950 chrX:153047070-153047190 chrX:153047290-153047570 chrX:153140500-153141210 chrX:153264620-153266010 chrX:153388430-153390880 chrX:153577400-153577720 chrX:153577930-153578010 chrX:153578240-153578390 chrX:153580390-153580540 chrX:153581570-153581660 chrX:153587520-153587610 chrX:153592530-153592620 chrX:153594590-153594670 chrX:153594840-153594920 chrX:153595010-153595090 chrX:153595910-153596000 chrX:153596110-153596200 chrX:153609160-153609240 chrX:153628970-153629040 chrX:153631180-153631280 chrX:153713990-153714100 chrX:153762380-153762550 chrX:153764260-153764350 chrX:153764390-153765460 chrX:153823850-153825690 chrX:153831670-153833120 chrX:153835720-153836080 chrX:152862440-152864410 chrX:153189420-153191580 chrX:153386930-153388190 chrX:153583440-153585080 chrX:153763600-153764150 chrX:153827980-153830400 chrX:153121950-153122700 chrX:153206620-153206930 chrX:153215230-153215520 chrX:153275300-153275950 chrX:152888140-152889370 chrX:153033370-153033660 chrX:153208530-153208990 chrX:153209170-153209340 chrX:153356850-153357640 chrX:153359370-153361130 chrX:153083630-153085470 chrX:153207110-153207400 chrX:153298710-153299520 chrX:153339100-153340730 chrX:153357770-153358900 chrX:152700210-152700690 chrX:152719970-152720330 chrX:152720510-152720990 chrX:152721220-152721720 chrX:152721820-152721950 chrX:152722110-152722590 chrX:152727530-152727670 chrX:152821880-152822370 chrX:153047660-153048220 chrX:153048330-153048400 chrX:153048570-153048680 chrX:153048700-153049200 chrX:153049340-153049420 chrX:153070360-153070550 chrX:153070660-153070950 chrX:153645430-153647880 chrX:153924300-153925400 chrX:153940980-153941480 chrX:153197880-153197990 chrX:153196720-153196880 chrX:153205690-153205830 chrX:153205910-153206340 chrX:153589940-153590030 chrX:153590160-153590340 chrX:153590520-153590600 chrX:153590950-153591020 chrX:153591150-153592380 chrX:153592740-153592890 chrX:153593090-153593180 chrX:153593330-153593500 chrX:153593630-153593710 chrX:153593860-153594390 chrX:152996090-152997200 |
|
| Promoter: |
chrX:153275957-153285353 |
ChIP-seq based regulatory details of IRAK1
| Sample ID | Experiment target | Biosample type | Biosample term name | GSM ID | Tissue type | Source |
|---|---|---|---|---|---|---|
| TcoF_00_20435 | IRAK1 | cell line | HEK293 | GSM2373678 | Embryonic Kidney | Cistrome |
Downstream target genes of IRAK1
Upstream regulatory details of IRAK1
Protein-protein interaction of IRAK1
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| IRAK1 | PRKCZ | Affinity Capture-Western | 11937546 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRAF6 | Affinity Capture-Western | 11518704 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRAK1BP1 | Two-hybrid | 11096118 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRAK1BP1 | Affinity Capture-Western | 11096118 | 9606 | 9606 | BIOGRID |
| IRAK1 | IKBKB | Affinity Capture-Western | 11096118 | 9606 | 9606 | BIOGRID |
| IRAK1 | CHUK | Affinity Capture-Western | 11096118 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRAF6 | Affinity Capture-Western | 10920205 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRAF6 | Two-hybrid | 11259596 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRAK1 | Two-hybrid | 11259596 | 9606 | 9606 | BIOGRID |
| IRAK1 | MYD88 | Affinity Capture-Western | 11544529 | 9606 | 9606 | BIOGRID |
| IRAK1 | IKBKG | Affinity Capture-Western | 18180283 | 9606 | 9606 | BIOGRID |
| IRAK1 | CHUK | Affinity Capture-Western | 18180283 | 9606 | 9606 | BIOGRID |
| IRAK1 | IKBKB | Affinity Capture-Western | 18180283 | 9606 | 9606 | BIOGRID |
| IRAK1 | BCL10 | Reconstituted Complex | 16831874 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRAF6 | Affinity Capture-Western | 11287640 | 9606 | 9606 | BIOGRID |
| IRAK1 | PELI1 | Biochemical Activity | 17997719 | 9606 | 9606 | BIOGRID |
| IRAK1 | PPP2CA | Affinity Capture-Western | 21708940 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRAF6 | Affinity Capture-Western | 21220427 | 9606 | 9606 | BIOGRID |
| IRAK1 | TNFAIP3 | Affinity Capture-Western | 21220427 | 9606 | 9606 | BIOGRID |
| IRAK1 | PELI1 | Biochemical Activity | 19264966 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRAF6 | Affinity Capture-Western | 20043910 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRIM32 | Affinity Capture-MS | 21903422 | 9606 | 9606 | BIOGRID |
| IRAK1 | BAG3 | Affinity Capture-MS | 21903422 | 9606 | 9606 | BIOGRID |
| IRAK1 | ADCK3 | Affinity Capture-MS | 21903422 | 9606 | 9606 | BIOGRID |
| IRAK1 | CCDC47 | Affinity Capture-MS | 21903422 | 9606 | 9606 | BIOGRID |
| IRAK1 | IQSEC1 | Affinity Capture-MS | 21903422 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRAK2 | Affinity Capture-MS | 21903422 | 9606 | 9606 | BIOGRID |
| IRAK1 | MAGED1 | Affinity Capture-MS | 21903422 | 9606 | 9606 | BIOGRID |
| IRAK1 | PJA1 | Affinity Capture-MS | 21903422 | 9606 | 9606 | BIOGRID |
| IRAK1 | PPP3CB | Affinity Capture-MS | 21903422 | 9606 | 9606 | BIOGRID |
| IRAK1 | RHOT1 | Affinity Capture-MS | 21903422 | 9606 | 9606 | BIOGRID |
| IRAK1 | SNRNP200 | Affinity Capture-MS | 21903422 | 9606 | 9606 | BIOGRID |
| IRAK1 | TARDBP | Affinity Capture-MS | 21903422 | 9606 | 9606 | BIOGRID |
| IRAK1 | TOMM70A | Affinity Capture-MS | 21903422 | 9606 | 9606 | BIOGRID |
| IRAK1 | YTHDC2 | Affinity Capture-MS | 21903422 | 9606 | 9606 | BIOGRID |
| IRAK1 | CCDC47 | Reconstituted Complex | 21903422 | 9606 | 9606 | BIOGRID |
| IRAK1 | PPP3CB | Reconstituted Complex | 21903422 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRIM32 | Reconstituted Complex | 21903422 | 9606 | 9606 | BIOGRID |
| IRAK1 | YTHDC2 | Reconstituted Complex | 21903422 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRAF6 | Affinity Capture-Western | 19716405 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRAK1 | Biochemical Activity | 18524972 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRAK1 | Biochemical Activity | 14625308 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRAF6 | Affinity Capture-Western | 14625308 | 9606 | 9606 | BIOGRID |
| IRAK1 | TOLLIP | Affinity Capture-Western | 17276401 | 9606 | 9606 | BIOGRID |
| IRAK1 | MYD88 | Affinity Capture-Western | 17276401 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRAK4 | Affinity Capture-Western | 17276401 | 9606 | 9606 | BIOGRID |
| IRAK1 | TOLLIP | Affinity Capture-Western | 16107720 | 9606 | 9606 | BIOGRID |
| IRAK1 | CAV1 | Affinity Capture-Western | 16107720 | 9606 | 9606 | BIOGRID |
| IRAK1 | PELI1 | Biochemical Activity | 21204785 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRAF6 | Affinity Capture-Western | 12242293 | 9606 | 9606 | BIOGRID |
| IRAK1 | IL1R1 | Affinity Capture-Western | 12242293 | 9606 | 9606 | BIOGRID |
| IRAK1 | MAP3K7 | Affinity Capture-Western | 12242293 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRAK1 | Biochemical Activity | 11397809 | 9606 | 9606 | BIOGRID |
| IRAK1 | TOLLIP | Affinity Capture-Western | 11397809 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRAF4 | Affinity Capture-Western | 16052631 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRF7 | Affinity Capture-Western | 15767370 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRF7 | FRET | 15767370 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRF7 | Biochemical Activity | 15767370 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRAF6 | Affinity Capture-Western | 17785851 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRAK4 | Affinity Capture-Western | 17785851 | 9606 | 9606 | BIOGRID |
| IRAK1 | BTRC | Affinity Capture-Western | 22851693 | 9606 | 9606 | BIOGRID |
| IRAK1 | FBXW11 | Affinity Capture-Western | 22851693 | 9606 | 9606 | BIOGRID |
| IRAK1 | CUL1 | Affinity Capture-Western | 22851693 | 9606 | 9606 | BIOGRID |
| IRAK1 | HSP90AA1 | Affinity Capture-Western | 15647277 | 9606 | 9606 | BIOGRID |
| IRAK1 | CDC37 | Affinity Capture-Western | 15647277 | 9606 | 9606 | BIOGRID |
| IRAK1 | HSPA4 | Affinity Capture-Western | 15647277 | 9606 | 9606 | BIOGRID |
| IRAK1 | STIP1 | Affinity Capture-Western | 15647277 | 9606 | 9606 | BIOGRID |
| IRAK1 | HSP90AA1 | Affinity Capture-MS | 15647277 | 9606 | 9606 | BIOGRID |
| IRAK1 | STIP1 | Affinity Capture-MS | 15647277 | 9606 | 9606 | BIOGRID |
| IRAK1 | HSPA4 | Affinity Capture-MS | 15647277 | 9606 | 9606 | BIOGRID |
| IRAK1 | HSP90AA1 | Co-fractionation | 15647277 | 9606 | 9606 | BIOGRID |
| IRAK1 | CDC37 | Co-fractionation | 15647277 | 9606 | 9606 | BIOGRID |
| IRAK1 | HIST3H3 | Biochemical Activity | 18276832 | 9606 | 9606 | BIOGRID |
| IRAK1 | PELI3 | Affinity Capture-Western | 12874243 | 9606 | 9606 | BIOGRID |
| IRAK1 | PELI2 | Biochemical Activity | 12860405 | 9606 | 9606 | BIOGRID |
| IRAK1 | NLRP12 | Affinity Capture-Western | 16203735 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRAK2 | FRET | 12138165 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRAK3 | FRET | 12138165 | 9606 | 9606 | BIOGRID |
| IRAK1 | STAT3 | Affinity Capture-Western | 15465816 | 9606 | 9606 | BIOGRID |
| IRAK1 | PRKCD | Affinity Capture-Western | 21804018 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRAF6 | Affinity Capture-Western | 19166926 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRAK1 | Affinity Capture-Western | 19166926 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRAK3 | Affinity Capture-Western | 19166926 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRAK4 | Affinity Capture-Western | 19166926 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRAK1 | Affinity Capture-Western | 16951688 | 9606 | 9606 | BIOGRID |
| IRAK1 | MYD88 | Affinity Capture-Western | 16951688 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRAF6 | Affinity Capture-Western | 16951688 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRAK4 | Affinity Capture-Western | 16951688 | 9606 | 9606 | BIOGRID |
| IRAK1 | PELI1 | Affinity Capture-Western | 16951688 | 9606 | 9606 | BIOGRID |
| IRAK1 | STAT1 | Affinity Capture-Western | 12856330 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRAK1 | Biochemical Activity | 16024789 | 9606 | 9606 | BIOGRID |
| IRAK1 | IRAK4 | Affinity Capture-Western | 16024789 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRAF6 | Affinity Capture-Western | 16024789 | 9606 | 9606 | BIOGRID |
| IRAK1 | MYD88 | Affinity Capture-Western | 16024789 | 9606 | 9606 | BIOGRID |
| IRAK1 | VASP | Affinity Capture-Western | 20044140 | 9606 | 9606 | BIOGRID |
| IRAK1 | HSPA8 | Affinity Capture-MS | 15647277 | 9606 | 9606 | BIOGRID |
| IRAK1 | ST13 | Affinity Capture-MS | 15647277 | 9606 | 9606 | BIOGRID |
| IRAK1 | ST13 | Affinity Capture-Western | 15647277 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRAF6 | Affinity Capture-Western | 23244239 | 9606 | 9606 | BIOGRID |
| IRAK1 | PINK1 | Affinity Capture-Western | 23244239 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRAF6 | Affinity Capture-Western | 23381138 | 9606 | 9606 | BIOGRID |
| IRAK1 | PELI1 | Affinity Capture-Western | 16884718 | 9606 | 9606 | BIOGRID |
| IRAK1 | PELI2 | Affinity Capture-Western | 16884718 | 9606 | 9606 | BIOGRID |
| IRAK1 | PELI3 | Affinity Capture-Western | 16884718 | 9606 | 9606 | BIOGRID |
| IRAK1 | SASH1 | Affinity Capture-Western | 23776175 | 9606 | 9606 | BIOGRID |
| IRAK1 | RNF31 | Affinity Capture-Western | 24491438 | 9606 | 9606 | BIOGRID |
| IRAK1 | AIFM1 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | ATP1A1 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | ATP5B | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | BAG2 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | CALU | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | CCT2 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | CCT3 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | CCT4 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | CCT5 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | CCT6A | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | CCT7 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | CCT8 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | DNAJA1 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | DNAJA2 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | DNAJA3 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | EEF2 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | EMD | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | HLA-A | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | HNRNPF | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | HSPB1 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | IMMT | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | LMNA | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | RCN1 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | SEC16A | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | SLC25A10 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | SLC25A13 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | SLC2A1 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | SLC7A5 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | STUB1 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | TCP1 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | TIMM50 | Affinity Capture-MS | 25852190 | 9606 | 9606 | BIOGRID |
| IRAK1 | OPTN | Two-hybrid | 28882891 | 9606 | 9606 | BIOGRID |
| IRAK1 | OPTN | Affinity Capture-Western | 28882891 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRAF6 | Affinity Capture-Western | 28882891 | 9606 | 9606 | BIOGRID |
| IRAK1 | IL1B | Co-localization | 10823834 | 9606 | 9606 | BIOGRID |
| IRAK1 | RSAD2 | Affinity Capture-Western | 30872404 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRAF6 | Affinity Capture-Western | 30872404 | 9606 | 9606 | BIOGRID |
| IRAK1 | RNF152 | Affinity Capture-Western | 31930677 | 9606 | 9606 | BIOGRID |
| IRAK1 | SMYD2 | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| IRAK1 | TRMT2A | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| IRAK1 | ZXDC | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| IRAK1 | Rsad2 | Affinity Capture-Western | 21435586 | 9606 | 10090 | BIOGRID |
| IRAK1 | Il1r1 | Two-hybrid | 9426216 | 9606 | 10090 | BIOGRID |
| IRAK1 | Il1r1 | Affinity Capture-Western | 9426216 | 9606 | 10090 | BIOGRID |
Annotation of IRAK1
TCGA cancer survival map of IRAK1
Expression of IRAK1
Disease information of IRAK1