TcoF overview
TcoF: KDM6A
GeneID: 4297
Name: Lysine-specific demethylase 6A
Ensembl: ENSG00000147050
Species: Human
Class: NA
Family: Lysine demethylase
Disease: 25
Go term: 26
Pathway: 3
Hallmark: --
Super Enhancer:

chrX:44731248-44734509 chrX:44807027-44834860 chrX:44731103-44781241 chrX:44730125-44735256 chrX:44730171-44924830 chrX:44730140-44951970 chrX:44730138-44981457 chrX:44732386-44827656

Enhancer:

chrX:44732960-44733160 chrX:44733230-44734820 chrX:44401350-44402050 chrX:44761990-44763020 chrX:44832550-44833910 chrX:44833960-44835890 chrX:45031920-45032870 chrX:44794840-44795730 chrX:44868070-44870200 chrX:44856160-44856930 chrX:44866110-44867620 chrX:44756820-44759190 chrX:44810770-44812970

Promoter:

chrX:44732423-44971847

 ChIP-seq based regulatory details of KDM6A
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
TcoF_00_31283 KDM6A cell line Jurkat GSM1581344 Blood ChIP-Atlas
TcoF_00_30907 KDM6A cell line CAL-51 GSM2561691 Breast ChIP-Atlas
TcoF_00_30908 KDM6A cell line CAL-51 GSM2561692 Breast ChIP-Atlas
TcoF_00_30909 KDM6A cell line CAL-51 GSM2561693 Breast ChIP-Atlas
TcoF_00_30910 KDM6A cell line CAL-51 GSM2561694 Breast ChIP-Atlas
TcoF_00_30905 KDM6A cell line CAL-51 GSM2648435 Breast ChIP-Atlas
TcoF_00_30906 KDM6A cell line CAL-51 GSM2648436 Breast ChIP-Atlas
TcoF_00_31107 KDM6A cell line Erythroblasts GSM3132546 Blood ChIP-Atlas
TcoF_00_31162 KDM6A cell line MCF-7 GSM3414798 Breast ChIP-Atlas
 Downstream target genes of KDM6A
 Protein-protein interaction of KDM6A
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
KDM6A TLE1 Two-hybrid 9854018 9606 9606 BIOGRID
KDM6A KMT2D Affinity Capture-MS 17761849 9606 9606 BIOGRID
KDM6A KMT2C Affinity Capture-MS 17761849 9606 9606 BIOGRID
KDM6A NCOA6 Affinity Capture-MS 17761849 9606 9606 BIOGRID
KDM6A N4BP2 Affinity Capture-MS 17761849 9606 9606 BIOGRID
KDM6A PAXIP1 Affinity Capture-MS 17761849 9606 9606 BIOGRID
KDM6A PPP6R3 Affinity Capture-MS 17761849 9606 9606 BIOGRID
KDM6A ZNF281 Affinity Capture-MS 17761849 9606 9606 BIOGRID
KDM6A PROSER1 Affinity Capture-MS 17761849 9606 9606 BIOGRID
KDM6A ASH2L Affinity Capture-MS 17761849 9606 9606 BIOGRID
KDM6A RBBP5 Affinity Capture-MS 17761849 9606 9606 BIOGRID
KDM6A WDR5 Affinity Capture-MS 17761849 9606 9606 BIOGRID
KDM6A HIST3H3 Biochemical Activity 17761849 9606 9606 BIOGRID
KDM6A PAXIP1 Affinity Capture-Western 17500065 9606 9606 BIOGRID
KDM6A RBBP5 Affinity Capture-Western 17500065 9606 9606 BIOGRID
KDM6A HIST1H3A Biochemical Activity 17713478 9606 9606 BIOGRID
KDM6A NKX2-5 Affinity Capture-Western 22192413 9606 9606 BIOGRID
KDM6A GATA4 Affinity Capture-Western 22192413 9606 9606 BIOGRID
KDM6A SRF Two-hybrid 22192413 9606 9606 BIOGRID
KDM6A TBX5 Two-hybrid 22192413 9606 9606 BIOGRID
KDM6A NKX2-5 Two-hybrid 22192413 9606 9606 BIOGRID
KDM6A HIST2H3C Biochemical Activity 21575637 9606 9606 BIOGRID
KDM6A WDR5 Affinity Capture-Western 17825402 9606 9606 BIOGRID
KDM6A ASH2L Affinity Capture-Western 17825402 9606 9606 BIOGRID
KDM6A RBBP5 Affinity Capture-Western 17825402 9606 9606 BIOGRID
KDM6A MSH6 Negative Genetic 28319113 9606 9606 BIOGRID
KDM6A PTEN Positive Genetic 28319113 9606 9606 BIOGRID
KDM6A KDM6A Negative Genetic 26864203 9606 9606 BIOGRID
KDM6A HDAC2 Negative Genetic 26864203 9606 9606 BIOGRID
KDM6A KDM5A Negative Genetic 26864203 9606 9606 BIOGRID
KDM6A KDM5C Negative Genetic 26864203 9606 9606 BIOGRID
KDM6A WDR5 Affinity Capture-MS 29785026 9606 9606 BIOGRID
KDM6A ASH2L Affinity Capture-MS 29785026 9606 9606 BIOGRID
KDM6A DPY30 Affinity Capture-MS 29785026 9606 9606 BIOGRID
KDM6A PAXIP1 Affinity Capture-MS 29785026 9606 9606 BIOGRID
KDM6A KMT2C Affinity Capture-MS 29785026 9606 9606 BIOGRID
KDM6A RBBP5 Affinity Capture-MS 29785026 9606 9606 BIOGRID
KDM6A KMT2D Affinity Capture-MS 29785026 9606 9606 BIOGRID
KDM6A NCOA6 Affinity Capture-MS 29785026 9606 9606 BIOGRID
KDM6A BAP1 Affinity Capture-MS 29785026 9606 9606 BIOGRID
KDM6A ASXL2 Affinity Capture-MS 29785026 9606 9606 BIOGRID
KDM6A ASXL1 Affinity Capture-MS 29785026 9606 9606 BIOGRID
KDM6A FOXK1 Affinity Capture-MS 29785026 9606 9606 BIOGRID
KDM6A ASXL3 Affinity Capture-MS 29785026 9606 9606 BIOGRID
KDM6A FOXK2 Affinity Capture-MS 29785026 9606 9606 BIOGRID
KDM6A OGT Affinity Capture-MS 29785026 9606 9606 BIOGRID
KDM6A BAP1 Affinity Capture-Western 29785026 9606 9606 BIOGRID
KDM6A RBBP5 Affinity Capture-Western 29785026 9606 9606 BIOGRID
KDM6A DPY30 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A KMT2D Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A WDR5 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A KMT2C Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A PAXIP1 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A NCOA6 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A PAGR1 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A KMT2B Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A CXXC1 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A KMT2A Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A HCFC2 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A HCFC1 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A SETD1B Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A KANSL2 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A BUB3 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A KANSL3 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A BOD1L1 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A MBIP Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A YEATS2 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A PRSS1 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A CSRP2BP Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A WDR82 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KDM6A KAT8 Affinity Capture-MS 24981860 9606 9606 BIOGRID
 Annotation of KDM6A
 TCGA cancer survival map of KDM6A


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  KDM6A