TcoF overview
TcoF: KMT2A
GeneID: 55904
Name: Histone-lysine N-methyltransferase 2A
Ensembl: ENSG00000118058
Species: Human
Class: NA
Family: Lysine methyltransferase
Disease: 44
Go term: 33
Pathway: 2
Hallmark: --
Super Enhancer:

--
Enhancer:

--
Promoter:

chr11:118307205-118397547

 ChIP-seq based regulatory details of KMT2A
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
TcoF_00_30347 KMT2A cell line ML-2 - Blood ChIP-Atlas
TcoF_00_31131 KMT2A cell line CD34+ GSM1313522 Blood ChIP-Atlas
TcoF_00_30578 KMT2A cell line MV-4-11 GSM1897369 Blood ChIP-Atlas
TcoF_00_30579 KMT2A cell line MV-4-11 GSM1897370 Blood ChIP-Atlas
TcoF_00_30587 KMT2A cell line SEM GSM1934095 Blood ChIP-Atlas
TcoF_00_30716 KMT2A cell line ML-2 GSM2212251 Blood ChIP-Atlas
TcoF_00_40993 KMT2A cell line THP-1 GSM2212253 Blood ReMap
TcoF_00_40313 KMT2A cell line KOPN-8 GSM2212255 Blood ReMap
TcoF_00_40315 KMT2A cell line MV4-11 GSM2212257 Blood ReMap
TcoF_00_40312 KMT2A cell line CCRF-CEM GSM2212259 Blood ReMap
TcoF_00_30753 KMT2A cell line MCF-7 GSM2264621 Breast ChIP-Atlas
TcoF_00_30799 KMT2A cell line SEM GSM2364542 Blood ChIP-Atlas
TcoF_00_40316 KMT2A cell line RCH-ACV GSM2364542 Blood ReMap
TcoF_00_40992 KMT2A cell line SEM GSM2364542 Blood ReMap
TcoF_00_30800 KMT2A cell line SEM GSM2364544 Blood ChIP-Atlas
TcoF_00_30801 KMT2A cell line SEM GSM2364547 Blood ChIP-Atlas
TcoF_00_30802 KMT2A cell line Unclassified GSM2364550 Unclassified ChIP-Atlas
TcoF_00_40314 KMT2A cell line L826 GSM2364550 None ReMap
TcoF_00_30803 KMT2A cell line Mononuclear GSM2364553 Blood ChIP-Atlas
TcoF_00_40991 KMT2A cell line blood_cord GSM2364553 Blood ReMap
TcoF_00_30804 KMT2A cell line Mononuclear GSM2364555 Blood ChIP-Atlas
TcoF_00_40311 KMT2A cell line bone-marrow_fetal GSM2364555 Bone Marrow ReMap
TcoF_00_30805 KMT2A cell line 293 GSM2373677 Kidney ChIP-Atlas
TcoF_00_30806 KMT2A cell line 293 GSM2373678 Kidney ChIP-Atlas
TcoF_00_30807 KMT2A cell line 293 GSM2373701 Kidney ChIP-Atlas
TcoF_00_30808 KMT2A cell line 293 GSM2373702 Kidney ChIP-Atlas
TcoF_00_30809 KMT2A cell line 293 GSM2373705 Kidney ChIP-Atlas
TcoF_00_30810 KMT2A cell line 293 GSM2373706 Kidney ChIP-Atlas
TcoF_00_31061 KMT2A cell line SHI-1 GSM2983930 Blood ChIP-Atlas
TcoF_00_40332 KMT2A cell line SHI-1 GSM2983930 Blood ReMap
TcoF_00_31169 KMT2A cell line 293 GSM3444914 Kidney ChIP-Atlas
TcoF_00_31170 KMT2A cell line 293 GSM3444915 Kidney ChIP-Atlas
TcoF_00_31172 KMT2A cell line 293 GSM3444918 Kidney ChIP-Atlas
TcoF_00_31173 KMT2A cell line 293 GSM3444919 Kidney ChIP-Atlas
TcoF_00_31175 KMT2A cell line 293 GSM3444922 Kidney ChIP-Atlas
TcoF_00_31176 KMT2A cell line 293 GSM3444923 Kidney ChIP-Atlas
TcoF_00_31178 KMT2A cell line 293 GSM3444926 Kidney ChIP-Atlas
TcoF_00_31179 KMT2A cell line 293 GSM3444927 Kidney ChIP-Atlas
TcoF_00_31180 KMT2A cell line 293 GSM3444929 Kidney ChIP-Atlas
TcoF_00_31181 KMT2A cell line 293 GSM3444930 Kidney ChIP-Atlas
TcoF_00_31182 KMT2A cell line 293 GSM3444932 Kidney ChIP-Atlas
TcoF_00_31183 KMT2A cell line 293 GSM3444933 Kidney ChIP-Atlas
TcoF_00_31184 KMT2A cell line 293 GSM3444935 Kidney ChIP-Atlas
TcoF_00_31185 KMT2A cell line 293 GSM3444936 Kidney ChIP-Atlas
TcoF_00_31186 KMT2A cell line MCF-7 GSM3444938 Breast ChIP-Atlas
TcoF_00_31187 KMT2A cell line MCF-7 GSM3444939 Breast ChIP-Atlas
TcoF_00_31188 KMT2A cell line MCF-7 GSM3444941 Breast ChIP-Atlas
TcoF_00_31189 KMT2A cell line MCF-7 GSM3444942 Breast ChIP-Atlas
TcoF_00_31190 KMT2A cell line 293 GSM3444948 Kidney ChIP-Atlas
TcoF_00_31191 KMT2A cell line 293 GSM3444949 Kidney ChIP-Atlas
TcoF_00_31192 KMT2A cell line 293 GSM3444950 Kidney ChIP-Atlas
TcoF_00_30633 KMT2A cell line RS4-11 GSM941543 Blood ChIP-Atlas
TcoF_00_40712 KMT2A cell line RS4-11 GSM941543 Blood ReMap
 Downstream target genes of KMT2A
 Protein-protein interaction of KMT2A
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
KMT2A PPIE Two-hybrid 11313484 9606 9606 BIOGRID
KMT2A PPP1R15A Two-hybrid 10490642 9606 9606 BIOGRID
KMT2A KMT2A Two-hybrid 11313484 9606 9606 BIOGRID
KMT2A ASH2L Affinity Capture-Western 15199122 9606 9606 BIOGRID
KMT2A ASH2L Co-purification 15199122 9606 9606 BIOGRID
KMT2A HCFC1 Co-purification 15199122 9606 9606 BIOGRID
KMT2A HCFC1 Affinity Capture-Western 15199122 9606 9606 BIOGRID
KMT2A HCFC2 Co-purification 15199122 9606 9606 BIOGRID
KMT2A HCFC2 Affinity Capture-Western 15199122 9606 9606 BIOGRID
KMT2A MEN1 Co-purification 15199122 9606 9606 BIOGRID
KMT2A MEN1 Affinity Capture-Western 15199122 9606 9606 BIOGRID
KMT2A RBBP5 Co-purification 15199122 9606 9606 BIOGRID
KMT2A RBBP5 Affinity Capture-Western 15199122 9606 9606 BIOGRID
KMT2A WDR5 Co-purification 15199122 9606 9606 BIOGRID
KMT2A WDR5 Affinity Capture-Western 15199122 9606 9606 BIOGRID
KMT2A AVP Biochemical Activity 14607844 9606 9606 BIOGRID
KMT2A INS Biochemical Activity 14607844 9606 9606 BIOGRID
KMT2A OXT Biochemical Activity 14607844 9606 9606 BIOGRID
KMT2A MAP3K5 Affinity Capture-Western 14607843 9606 9606 BIOGRID
KMT2A HDAC1 Reconstituted Complex 12829790 9606 9606 BIOGRID
KMT2A HDAC1 Affinity Capture-Western 12829790 9606 9606 BIOGRID
KMT2A CTBP1 Reconstituted Complex 12829790 9606 9606 BIOGRID
KMT2A CTBP1 Affinity Capture-Western 12829790 9606 9606 BIOGRID
KMT2A CBX4 Reconstituted Complex 12829790 9606 9606 BIOGRID
KMT2A BMI1 Reconstituted Complex 12829790 9606 9606 BIOGRID
KMT2A CREBBP Reconstituted Complex 11259575 9606 9606 BIOGRID
KMT2A PPP1R15A Affinity Capture-Western 10490642 9606 9606 BIOGRID
KMT2A SMARCB1 Affinity Capture-Western 10490642 9606 9606 BIOGRID
KMT2A KMT2A Reconstituted Complex 11313484 9606 9606 BIOGRID
KMT2A PPIE Affinity Capture-Western 11313484 9606 9606 BIOGRID
KMT2A KMT2A Affinity Capture-Western 12482972 9606 9606 BIOGRID
KMT2A KMT2A Reconstituted Complex 12482972 9606 9606 BIOGRID
KMT2A KMT2A Affinity Capture-Western 12393701 9606 9606 BIOGRID
KMT2A KMT2A Reconstituted Complex 12393701 9606 9606 BIOGRID
KMT2A CXXC1 Affinity Capture-Western 18082152 9606 9606 BIOGRID
KMT2A PPIE Affinity Capture-Western 18676843 9606 9606 BIOGRID
KMT2A WDR5 Reconstituted Complex 18840606 9606 9606 BIOGRID
KMT2A MEN1 Affinity Capture-Western 16618927 9606 9606 BIOGRID
KMT2A PSIP1 Affinity Capture-Western 18598942 9606 9606 BIOGRID
KMT2A MLLT4 Affinity Capture-Western 16239140 9606 9606 BIOGRID
KMT2A MEN1 Affinity Capture-Western 16239140 9606 9606 BIOGRID
KMT2A MEN1 Reconstituted Complex 16239140 9606 9606 BIOGRID
KMT2A POLR2A Affinity Capture-Western 16199523 9606 9606 BIOGRID
KMT2A MEN1 Affinity Capture-Western 16199523 9606 9606 BIOGRID
KMT2A MEN1 Co-localization 16199523 9606 9606 BIOGRID
KMT2A SBF1 Reconstituted Complex 9537414 9606 9606 BIOGRID
KMT2A MTM1 Reconstituted Complex 9537414 9606 9606 BIOGRID
KMT2A SET Two-hybrid 9353299 9606 9606 BIOGRID
KMT2A SET Reconstituted Complex 9353299 9606 9606 BIOGRID
KMT2A MEN1 Affinity Capture-Western 17671196 9606 9606 BIOGRID
KMT2A HIST1H3A Reconstituted Complex 20452361 9606 9606 BIOGRID
KMT2A HIST1H4A Reconstituted Complex 20452361 9606 9606 BIOGRID
KMT2A KAT6A Affinity Capture-Western 20581860 9606 9606 BIOGRID
KMT2A WDR5 Affinity Capture-Western 20581860 9606 9606 BIOGRID
KMT2A ELL Affinity Capture-Western 20153263 9606 9606 BIOGRID
KMT2A AFF1 Affinity Capture-Western 20153263 9606 9606 BIOGRID
KMT2A AFF4 Affinity Capture-Western 20153263 9606 9606 BIOGRID
KMT2A CDK9 Affinity Capture-Western 20153263 9606 9606 BIOGRID
KMT2A CCNT1 Affinity Capture-Western 20153263 9606 9606 BIOGRID
KMT2A CTR9 Affinity Capture-MS 20541477 9606 9606 BIOGRID
KMT2A LEO1 Affinity Capture-MS 20541477 9606 9606 BIOGRID
KMT2A PAF1 Affinity Capture-MS 20541477 9606 9606 BIOGRID
KMT2A CDC73 Affinity Capture-MS 20541477 9606 9606 BIOGRID
KMT2A WDR61 Affinity Capture-MS 20541477 9606 9606 BIOGRID
KMT2A CTR9 Affinity Capture-Western 20541477 9606 9606 BIOGRID
KMT2A LEO1 Affinity Capture-Western 20541477 9606 9606 BIOGRID
KMT2A PAF1 Affinity Capture-Western 20541477 9606 9606 BIOGRID
KMT2A CDC73 Affinity Capture-Western 20541477 9606 9606 BIOGRID
KMT2A WDR61 Affinity Capture-Western 20541477 9606 9606 BIOGRID
KMT2A CTR9 Reconstituted Complex 20541477 9606 9606 BIOGRID
KMT2A PAF1 Reconstituted Complex 20541477 9606 9606 BIOGRID
KMT2A MLLT3 Affinity Capture-Western 20854876 9606 9606 BIOGRID
KMT2A CDK9 Affinity Capture-Western 20854876 9606 9606 BIOGRID
KMT2A DOT1L Affinity Capture-Western 20854876 9606 9606 BIOGRID
KMT2A SKP2 Affinity Capture-Western 20818375 9606 9606 BIOGRID
KMT2A HIST3H3 Biochemical Activity 21124902 9606 9606 BIOGRID
KMT2A HIST1H3A Co-crystal Structure 20541251 9606 9606 BIOGRID
KMT2A PPIE Co-crystal Structure 20541251 9606 9606 BIOGRID
KMT2A HIST3H3 Biochemical Activity 21030982 9606 9606 BIOGRID
KMT2A HIST2H3C Biochemical Activity 21726816 9606 9606 BIOGRID
KMT2A SIN3A Affinity Capture-MS 20153263 9606 9606 BIOGRID
KMT2A MLLT1 Affinity Capture-Western 20153263 9606 9606 BIOGRID
KMT2A RUNX1 Affinity Capture-Western 22012064 9606 9606 BIOGRID
KMT2A CBFB Affinity Capture-Western 22012064 9606 9606 BIOGRID
KMT2A H3F3A Biochemical Activity 17166833 9606 9606 BIOGRID
KMT2A WDR5 Affinity Capture-Western 22665483 9606 9606 BIOGRID
KMT2A RBBP5 Affinity Capture-Western 22665483 9606 9606 BIOGRID
KMT2A ASH2L Affinity Capture-Western 22665483 9606 9606 BIOGRID
KMT2A WDR5 Protein-peptide 22665483 9606 9606 BIOGRID
KMT2A ASB2 Affinity Capture-Western 22174154 9606 9606 BIOGRID
KMT2A TCEB1 Affinity Capture-Western 22174154 9606 9606 BIOGRID
KMT2A TCEB2 Affinity Capture-Western 22174154 9606 9606 BIOGRID
KMT2A CDK9 Affinity Capture-Western 22094252 9606 9606 BIOGRID
KMT2A CCNT1 Affinity Capture-Western 22094252 9606 9606 BIOGRID
KMT2A AFF4 Affinity Capture-Western 22094252 9606 9606 BIOGRID
KMT2A DOT1L Affinity Capture-Western 22094252 9606 9606 BIOGRID
KMT2A TAF6 Co-fractionation 22939629 9606 9606 BIOGRID
KMT2A NCL Co-fractionation 22939629 9606 9606 BIOGRID
KMT2A SYMPK Affinity Capture-Western 23994619 9606 9606 BIOGRID
KMT2A KMT2A Biochemical Activity 24235145 9606 9606 BIOGRID
KMT2A ASH2L Biochemical Activity 24235145 9606 9606 BIOGRID
KMT2A RBBP5 Affinity Capture-Western 24081332 9606 9606 BIOGRID
KMT2A ASH2L Affinity Capture-Western 23870121 9606 9606 BIOGRID
KMT2A RBBP5 Affinity Capture-Western 23870121 9606 9606 BIOGRID
KMT2A WDR5 Affinity Capture-Western 23870121 9606 9606 BIOGRID
KMT2A HCFC1 Affinity Capture-Western 23870121 9606 9606 BIOGRID
KMT2A HIST1H3A Biochemical Activity 24680668 9606 9606 BIOGRID
KMT2A WDR5 Reconstituted Complex 24680668 9606 9606 BIOGRID
KMT2A HIST1H3A Biochemical Activity 12453419 9606 9606 BIOGRID
KMT2A TAF1 Affinity Capture-Western 12453419 9606 9606 BIOGRID
KMT2A CHD3 Affinity Capture-Western 12453419 9606 9606 BIOGRID
KMT2A SMARCA2 Affinity Capture-Western 12453419 9606 9606 BIOGRID
KMT2A SMARCC2 Affinity Capture-Western 12453419 9606 9606 BIOGRID
KMT2A SMARCC1 Affinity Capture-Western 12453419 9606 9606 BIOGRID
KMT2A SIN3A Affinity Capture-Western 12453419 9606 9606 BIOGRID
KMT2A TAF6 Affinity Capture-Western 12453419 9606 9606 BIOGRID
KMT2A HDAC1 Affinity Capture-Western 12453419 9606 9606 BIOGRID
KMT2A HDAC2 Affinity Capture-Western 12453419 9606 9606 BIOGRID
KMT2A RBBP4 Affinity Capture-Western 12453419 9606 9606 BIOGRID
KMT2A RBBP7 Affinity Capture-Western 12453419 9606 9606 BIOGRID
KMT2A SMARCB1 Affinity Capture-Western 12453419 9606 9606 BIOGRID
KMT2A TBP Affinity Capture-Western 12453419 9606 9606 BIOGRID
KMT2A MBD3 Affinity Capture-Western 12453419 9606 9606 BIOGRID
KMT2A SAP30 Affinity Capture-Western 12453419 9606 9606 BIOGRID
KMT2A RAN Affinity Capture-Western 12453419 9606 9606 BIOGRID
KMT2A TAF9 Affinity Capture-Western 12453419 9606 9606 BIOGRID
KMT2A TAF9 Reconstituted Complex 10821850 9606 9606 BIOGRID
KMT2A HIST3H3 Biochemical Activity 26324722 9606 9606 BIOGRID
KMT2A HIST1H3A Biochemical Activity 24235145 9606 9606 BIOGRID
KMT2A WDR5 Reconstituted Complex 27563068 9606 9606 BIOGRID
KMT2A RBBP5 Reconstituted Complex 27563068 9606 9606 BIOGRID
KMT2A ASH2L Reconstituted Complex 27563068 9606 9606 BIOGRID
KMT2A AR Affinity Capture-Western 22722839 9606 9606 BIOGRID
KMT2A KMT2A Two-hybrid 10656681 9606 9606 BIOGRID
KMT2A KMT2A Reconstituted Complex 10656681 9606 9606 BIOGRID
KMT2A KMT2A Affinity Capture-Western 10656681 9606 9606 BIOGRID
KMT2A WDR5 Co-purification 28182322 9606 9606 BIOGRID
KMT2A ASH2L Co-purification 28182322 9606 9606 BIOGRID
KMT2A RBBP5 Co-purification 28182322 9606 9606 BIOGRID
KMT2A HIST3H3 Biochemical Activity 28182322 9606 9606 BIOGRID
KMT2A WDR5 Reconstituted Complex 28182322 9606 9606 BIOGRID
KMT2A ASH2L Reconstituted Complex 28182322 9606 9606 BIOGRID
KMT2A RBBP5 Reconstituted Complex 28182322 9606 9606 BIOGRID
KMT2A CKS1B Affinity Capture-Western 28939057 9606 9606 BIOGRID
KMT2A CKS2 Affinity Capture-Western 28939057 9606 9606 BIOGRID
KMT2A MED17 Negative Genetic 28481362 9606 9606 BIOGRID
KMT2A WDR82 Negative Genetic 28481362 9606 9606 BIOGRID
KMT2A RUVBL1 Positive Genetic 28481362 9606 9606 BIOGRID
KMT2A MCM2 Positive Genetic 28481362 9606 9606 BIOGRID
KMT2A RTF1 Positive Genetic 28481362 9606 9606 BIOGRID
KMT2A MED15 Positive Genetic 28481362 9606 9606 BIOGRID
KMT2A MED8 Positive Genetic 28481362 9606 9606 BIOGRID
KMT2A MRGBP Positive Genetic 28481362 9606 9606 BIOGRID
KMT2A PAF1 Positive Genetic 28481362 9606 9606 BIOGRID
KMT2A MED14 Positive Genetic 28481362 9606 9606 BIOGRID
KMT2A WDR5 Affinity Capture-Western 27192115 9606 9606 BIOGRID
KMT2A HIST1H3A Biochemical Activity 29897600 9606 9606 BIOGRID
KMT2A RBBP5 Reconstituted Complex 31400120 9606 9606 BIOGRID
KMT2A HIST1H3A Biochemical Activity 31485071 9606 9606 BIOGRID
KMT2A ASH2L Affinity Capture-Western 31685992 9606 9606 BIOGRID
KMT2A RBBP5 Affinity Capture-Western 31685992 9606 9606 BIOGRID
KMT2A WDR5 Affinity Capture-Western 31685992 9606 9606 BIOGRID
KMT2A DPY30 Affinity Capture-Western 31685992 9606 9606 BIOGRID
KMT2A PTEN Affinity Capture-Western 31685992 9606 9606 BIOGRID
KMT2A RBBP5 Reconstituted Complex 31544921 9606 9606 BIOGRID
KMT2A HIST1H3A Biochemical Activity 31544921 9606 9606 BIOGRID
KMT2A TMCO1 Proximity Label-MS 30021884 9606 9606 BIOGRID
KMT2A KMT2B Affinity Capture-MS 24981860 9606 9606 BIOGRID
KMT2A CXXC1 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KMT2A WDR5 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KMT2A HCFC1 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KMT2A DPY30 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KMT2A KANSL2 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KMT2A BUB3 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KMT2A SETD1B Affinity Capture-MS 24981860 9606 9606 BIOGRID
KMT2A WDR82 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KMT2A MBIP Affinity Capture-MS 24981860 9606 9606 BIOGRID
KMT2A KANSL3 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KMT2A BOD1L1 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KMT2A CSRP2BP Affinity Capture-MS 24981860 9606 9606 BIOGRID
KMT2A ZNF608 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KMT2A ATN1 Affinity Capture-MS 24981860 9606 9606 BIOGRID
KMT2A NCOA6 Affinity Capture-MS 24981860 9606 9606 BIOGRID
 Annotation of KMT2A
 TCGA cancer survival map of KMT2A


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  KMT2A