TcoF overview
TcoF: MAP2K3
GeneID: 2475
Name: Dual-specificity mitogen-activated protein kinase kinase 3
Ensembl: ENSG00000034152
Species: Human
Class: class 1
Family: Others
Disease: 1
Go term: 24
Pathway: 59
Hallmark: 1
Super Enhancer:

chr17:21102632-21145468 chr17:21188331-21191900 chr17:21163641-21194034 chr17:21181051-21194284 chr17:21163125-21193657 chr17:21163626-21193196 chr17:21185231-21192542 chr17:21178593-21194225 chr17:21181515-21193766 chr17:21163640-21193414 chr17:21187932-21191286 chr17:21186961-21210193 chr17:21178206-21194430 chr17:21187914-21194181 chr17:21185133-21194267 chr17:21178713-21192495 chr17:21178722-21192565 chr17:21178508-21193515 chr17:21178517-21193199 chr17:21187013-21193224 chr17:21178827-21194005 chr17:21163560-21193282 chr17:21178597-21192210 chr17:21181157-21214627 chr17:21213607-21233399 chr17:21180862-21194516 chr17:21178492-21192914 chr17:21182636-21221166 chr17:21187622-21194077 chr17:21178401-21194131 chr17:21178322-21198945 chr17:21178548-21193887 chr17:21178417-21199060 chr17:21178300-21199195 chr17:21178414-21199021 chr17:21178353-21220963 chr17:21178592-21195032 chr17:21178408-21194244 chr17:21170768-21226865 chr17:21178495-21194158 chr17:21183884-21194392 chr17:21178621-21192888 chr17:21178736-21193310 chr17:21178482-21192708 chr17:21163923-21192315 chr17:21163887-21191299 chr17:21163939-21200542 chr17:21178443-21202986 chr17:21178482-21220908 chr17:21178870-21223446 chr17:21178360-21199091 chr17:21178372-21193823 chr17:21177654-21194053 chr17:21178516-21199108 chr17:21178356-21198842 chr17:21180778-21194245 chr17:21187949-21192963 chr17:21170678-21255570 chr17:21178306-21193910 chr17:21178790-21191343 chr17:21183040-21226607 chr17:21184105-21226701 chr17:21183342-21209480 chr17:21185020-21193933 chr17:21178485-21193067 chr17:21178209-21193947 chr17:21188167-21191293 chr17:21178425-21201742 chr17:21194855-21224828 chr17:21198092-21227567 chr17:21178549-21226620 chr17:21178593-21199781 chr17:21163774-21199335 chr17:21178351-21200186 chr17:21178461-21193483 chr17:21178449-21194413 chr17:21178242-21201466 chr17:21178557-21201443 chr17:21186819-21194102 chr17:21184880-21220359 chr17:21178411-21193958 chr17:21178615-21193836 chr17:21178903-21193823 chr17:21213405-21274408 chr17:21178534-21194221 chr17:21178498-21200597 chr17:21186430-21215875 chr17:21187061-21215485 chr17:21178445-21194457 chr17:21187941-21200177 chr17:21178469-21194564 chr17:21178324-21194240 chr17:21178307-21194032 chr17:21184699-21204572 chr17:21189084-21200246 chr17:21178299-21201323 chr17:21174558-21202700 chr17:21143057-21226900 chr17:21149979-21202901 chr17:21219051-21233235 chr17:21144020-21203293 chr17:21143303-21227515

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Enhancer:

chr17:21206540-21207730 chr17:20908300-20910200 chr17:21146740-21147410 chr17:21153860-21155390 chr17:21155570-21156470 chr17:21213130-21215450 chr17:21225300-21227570 chr17:21287630-21288350 chr17:21476750-21478360 chr17:21282670-21283270 chr17:20754800-20756850 chr17:21201790-21202180 chr17:21202230-21203850 chr17:21205570-21206490 chr17:21075510-21076430 chr17:21262060-21263340 chr17:21332410-21334190 chr17:21252170-21254430 chr17:20851570-20852410 chr17:21215590-21216800 chr17:21216840-21217450 chr17:20825300-20826460 chr17:20931990-20932820 chr17:20823780-20825220 chr17:21033910-21035570 chr17:21049890-21050440 chr17:21510770-21512470 chr17:21170540-21172610 chr17:21280230-21282540 chr17:21165920-21168240 chr17:20857250-20859500 chr17:21239700-21241730 chr17:20863790-20866220 chr17:20900470-20902900 chr17:20906390-20907510 chr17:20939350-20941260 chr17:20941590-20941890 chr17:21148510-21149620 chr17:21153130-21153760 chr17:21248340-21248940 chr17:21316330-21317410 chr17:21549690-21552160 chr17:20921420-20922390 chr17:21249270-21251240 chr17:21208440-21210900 chr17:21323180-21325190 chr17:21325270-21327260 chr17:21313720-21315820 chr17:20943530-20945970 chr17:21064710-21067040

--
Promoter:

chr17:21187984-21218544

False
 ChIP-seq based regulatory details of MAP2K3
select * from encode where Experiment_target='MAP2K3'
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
 Downstream target genes of MAP2K3
 Protein-protein interaction of MAP2K3
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
MAP2K3 MAPK3 Reconstituted Complex 8226933 9606 9606 BIOGRID
MAP2K3 MAPK14 Biochemical Activity 11279118 9606 9606 BIOGRID
MAP2K3 MAP2K6 Phenotypic Enhancement 11562357 9606 9606 BIOGRID
MAP2K3 RPL13 Two-hybrid 21900206 9606 9606 BIOGRID
MAP2K3 MAP3K4 Reconstituted Complex 15866172 9606 9606 BIOGRID
MAP2K3 MAP2K3 Biochemical Activity 9162092 9606 9606 BIOGRID
MAP2K3 MAPK14 Biochemical Activity 9162092 9606 9606 BIOGRID
MAP2K3 LRRK2 Affinity Capture-Western 20173330 9606 9606 BIOGRID
MAP2K3 MAPK8IP1 Affinity Capture-Western 20173330 9606 9606 BIOGRID
MAP2K3 MAPK8IP2 Affinity Capture-Western 20173330 9606 9606 BIOGRID
MAP2K3 MAPK8IP3 Affinity Capture-Western 20173330 9606 9606 BIOGRID
MAP2K3 SPAG9 Affinity Capture-Western 20173330 9606 9606 BIOGRID
MAP2K3 MAPK14 Biochemical Activity 20213747 9606 9606 BIOGRID
MAP2K3 APP Reconstituted Complex 21832049 9606 9606 BIOGRID
MAP2K3 MAP3K5 Affinity Capture-Western 16709866 9606 9606 BIOGRID
MAP2K3 MAP2K6 Co-localization 25241761 9606 9606 BIOGRID
MAP2K3 MAP3K4 Co-localization 25241761 9606 9606 BIOGRID
MAP2K3 TAOK2 Co-localization 25241761 9606 9606 BIOGRID
MAP2K3 MAPK14 FRET 23904011 9606 9606 BIOGRID
MAP2K3 MAP3K5 Affinity Capture-Western 19805025 9606 9606 BIOGRID
MAP2K3 SMAD3 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 RPL13 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 CDK9 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 HSPD1 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 TARDBP Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 HOXB9 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 RPL4 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 RPL24 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 HNRNPUL1 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 TUBB Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 NPM1 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 RPL7 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 DDX24 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 RPL30 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 RPS26 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 MICAL2 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 RPS28 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 PCBP1 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 DDX5 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 RPL28 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 HNRNPK Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 DIMT1 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 SLC25A5 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 RPL19 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 TRIP12 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 RPS3A Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 RPS6 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 DHX9 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 RPL3 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 DVL1 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 ZNF598 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 U2AF2 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 SRPK2 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 GOLGA2 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 RPL21 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 YWHAZ Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 TUBB3 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 ILF3 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 SRPK1 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 BUD13 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 ANKRD17 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 HSP90AA1 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 NCL Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 RPL29 Affinity Capture-MS 27684187 9606 9606 BIOGRID
MAP2K3 MYC Affinity Capture-Western 28205554 9606 9606 BIOGRID
MAP2K3 AKT1 FRET 28205554 9606 9606 BIOGRID
MAP2K3 ARNT FRET 28205554 9606 9606 BIOGRID
MAP2K3 AURKA FRET 28205554 9606 9606 BIOGRID
MAP2K3 CCND2 FRET 28205554 9606 9606 BIOGRID
MAP2K3 CDK4 FRET 28205554 9606 9606 BIOGRID
MAP2K3 CDK6 FRET 28205554 9606 9606 BIOGRID
MAP2K3 CD44 FRET 28205554 9606 9606 BIOGRID
MAP2K3 CDC42 FRET 28205554 9606 9606 BIOGRID
MAP2K3 CDKN2B FRET 28205554 9606 9606 BIOGRID
MAP2K3 CDKN2C FRET 28205554 9606 9606 BIOGRID
MAP2K3 ERBB2 FRET 28205554 9606 9606 BIOGRID
MAP2K3 HIF1A FRET 28205554 9606 9606 BIOGRID
MAP2K3 KAT2A FRET 28205554 9606 9606 BIOGRID
MAP2K3 MAP2K3 FRET 28205554 9606 9606 BIOGRID
MAP2K3 MAP3K5 FRET 28205554 9606 9606 BIOGRID
MAP2K3 MET FRET 28205554 9606 9606 BIOGRID
MAP2K3 ARNT FRET 28628118 9606 9606 BIOGRID
MAP2K3 AURKA FRET 28628118 9606 9606 BIOGRID
MAP2K3 BECN1 FRET 28628118 9606 9606 BIOGRID
MAP2K3 EPHA2 FRET 28628118 9606 9606 BIOGRID
MAP2K3 FGFR4 FRET 28628118 9606 9606 BIOGRID
MAP2K3 MAPK14 FRET 28628118 9606 9606 BIOGRID
MAP2K3 MYC FRET 28628118 9606 9606 BIOGRID
MAP2K3 PDGFRA FRET 28628118 9606 9606 BIOGRID
MAP2K3 RASSF1 FRET 28628118 9606 9606 BIOGRID
MAP2K3 STK11 FRET 28628118 9606 9606 BIOGRID
MAP2K3 ARNT Affinity Capture-Western 28628118 9606 9606 BIOGRID
MAP2K3 AURKA Affinity Capture-Western 28628118 9606 9606 BIOGRID
MAP2K3 BECN1 Affinity Capture-Western 28628118 9606 9606 BIOGRID
MAP2K3 EPHA2 Affinity Capture-Western 28628118 9606 9606 BIOGRID
MAP2K3 FGFR4 Affinity Capture-Western 28628118 9606 9606 BIOGRID
MAP2K3 MAPK14 Affinity Capture-Western 28628118 9606 9606 BIOGRID
MAP2K3 MYC Affinity Capture-Western 28628118 9606 9606 BIOGRID
MAP2K3 PDGFRA Affinity Capture-Western 28628118 9606 9606 BIOGRID
MAP2K3 RASSF1 Affinity Capture-Western 28628118 9606 9606 BIOGRID
MAP2K3 STK11 Affinity Capture-Western 28628118 9606 9606 BIOGRID
MAP2K3 PDAP1 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 PPP2CB Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 PDCD4 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 AKAP12 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 SLC25A3 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 TUBB4B Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 TUBA1B Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 TUBB Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 SLC25A5 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 CDC37 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 HSPA9 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 HSPA6 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 HSPA8 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 HSPA1A Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 HSPB1 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 DNAJA1 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 PPP2CA Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 SFN Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 PPP2R1A Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 CAD Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 HSPA5 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 HSPH1 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 SLC3A2 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 USP7 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 HSPA4 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 RPS21 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 CTNNA1 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 TUBB6 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 TUBA1C Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 MMS19 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 TUBB8 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 TUBB2A Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 DNAJA2 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 NPM1 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 USP9X Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 USP11 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 BTF3 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 HSPA4L Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 RUVBL1 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 RUVBL2 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 NPM3 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 DNAJB11 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 HSPBP1 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 MAP3K5 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 USP9Y Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 NAPRT Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 DCAF8 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 RBBP7 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 DDB1 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 MAD2L1 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 RBBP4 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 GNB2L1 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 EIF6 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 CTNNB1 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 CTPS1 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 RPSA Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 MAP3K6 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 HAT1 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 PSMA7 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 SUPT5H Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 HDAC2 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 MTA1 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 HUWE1 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 EIF1AX Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 EIF1AY Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 FAT1 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 BCAP31 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 POLR2B Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 CTNNA2 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 GRB2 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 MAP2K3 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 MAPK1 Affinity Capture-MS 31980649 9606 9606 BIOGRID
MAP2K3 MAPK14 Affinity Capture-MS 31980649 9606 9606 BIOGRID
 Annotation of MAP2K3
 TCGA cancer survival map of MAP2K3


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  MAP2K3