TcoF overview
| TcoF: | MLLT3 | |
| GeneID: | 4332 | |
| Name: | Myeloid/lymphoid or mixed-lineage leukemia | |
| Ensembl: | ENSG00000171843 | |
| Species: | Human | |
| Class: | NA | |
| Family: | GTF | |
| Disease: | 1 | |
| Go term: | 22 | |
| Pathway: | -- | |
| Hallmark: | -- | |
| Super Enhancer: |
chr9:20356856-20399401 chr9:20597753-20641920 chr9:20549728-20571432 chr9:20549922-20571327 chr9:20415799-20446393 chr9:20551370-20582823 chr9:20549774-20571370 chr9:20594190-20620502 chr9:20548666-20558697 chr9:20601092-20627046 chr9:20590774-20626072 chr9:20300787-20414345 chr9:20597880-20624147 chr9:20467704-20497225 chr9:20619358-20625075 chr9:20549920-20572831 |
|
| Enhancer: |
chr9:20620830-20621770 chr9:20658460-20658680 chr9:20683540-20684570 chr9:20698290-20699600 chr9:20759670-20761900 chr9:20804290-20805760 chr9:21029400-21031550 chr9:20680810-20683300 chr9:20990370-20991790 chr9:20270940-20271440 chr9:20962250-20963550 chr9:20550650-20552710 chr9:20604240-20605280 chr9:20634770-20636660 chr9:20636880-20637660 chr9:20639800-20641890 chr9:20699860-20701980 chr9:20297100-20298480 chr9:20350560-20352650 chr9:20353140-20353520 chr9:20557520-20560020 chr9:20592290-20594250 chr9:20598830-20600090 chr9:20601630-20602100 chr9:20678280-20679940 chr9:20511340-20513840 chr9:20692340-20693400 chr9:20658830-20660460 chr9:20218750-20219830 chr9:20220080-20220850 chr9:20579610-20581910 chr9:20722020-20723150 chr9:20312680-20313090 chr9:20318880-20321380 chr9:20321520-20322510 chr9:20477680-20479120 chr9:20770330-20772290 chr9:20872190-20874360 chr9:20611080-20612690 chr9:20898220-20900420 chr9:20905140-20907140 chr9:20407700-20409190 chr9:20835280-20836230 |
|
| Promoter: |
chr9:20341667-20622517 |
ChIP-seq based regulatory details of MLLT3
| Sample ID | Experiment target | Biosample type | Biosample term name | GSM ID | Tissue type | Source |
|---|---|---|---|---|---|---|
| TcoF_00_31132 | MLLT3 | cell line | CD34+ | GSM1313523 | Blood | ChIP-Atlas |
| TcoF_00_40275 | MLLT3 | cell line | CD34 | GSM1313523 | Blood | ReMap |
| TcoF_00_31235 | MLLT3 | cell line | HeLa | GSM1477294 | Uterus | ChIP-Atlas |
| TcoF_00_30445 | MLLT3 | cell line | hESC derived neural cells | GSM1668530 | Embryo | ChIP-Atlas |
| TcoF_00_40913 | MLLT3 | cell line | NPCS | GSM1668530 | Neural | ReMap |
| TcoF_00_40983 | MLLT3 | cell line | THP-1 | GSM2108049 | Blood | ReMap |
| TcoF_00_30962 | MLLT3 | cell | CD34+ cells | GSM2786822 | Blood | ChIP-Atlas |
Downstream target genes of MLLT3
Upstream regulatory details of MLLT3
Protein-protein interaction of MLLT3
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| MLLT3 | APPBP2 | Two-hybrid | 16189514 | 9606 | 9606 | BIOGRID |
| MLLT3 | BCOR | Affinity Capture-Western | 12776190 | 9606 | 9606 | BIOGRID |
| MLLT3 | RBM48 | Two-hybrid | 16169070 | 9606 | 9606 | BIOGRID |
| MLLT3 | EEF1A1 | Two-hybrid | 16169070 | 9606 | 9606 | BIOGRID |
| MLLT3 | PTN | Two-hybrid | 16169070 | 9606 | 9606 | BIOGRID |
| MLLT3 | LRIF1 | Two-hybrid | 16169070 | 9606 | 9606 | BIOGRID |
| MLLT3 | DOT1L | Reconstituted Complex | 16636056 | 9606 | 9606 | BIOGRID |
| MLLT3 | DOT1L | Affinity Capture-Western | 16636056 | 9606 | 9606 | BIOGRID |
| MLLT3 | DOT1L | Reconstituted Complex | 17332896 | 9606 | 9606 | BIOGRID |
| MLLT3 | AFF4 | Affinity Capture-MS | 20431927 | 9606 | 9606 | BIOGRID |
| MLLT3 | AFF1 | Affinity Capture-MS | 20431927 | 9606 | 9606 | BIOGRID |
| MLLT3 | BCOR | Affinity Capture-MS | 20431927 | 9606 | 9606 | BIOGRID |
| MLLT3 | CDK9 | Affinity Capture-MS | 20431927 | 9606 | 9606 | BIOGRID |
| MLLT3 | DOT1L | Affinity Capture-MS | 20431927 | 9606 | 9606 | BIOGRID |
| MLLT3 | AFF3 | Affinity Capture-MS | 20431927 | 9606 | 9606 | BIOGRID |
| MLLT3 | ACACA | Affinity Capture-MS | 20431927 | 9606 | 9606 | BIOGRID |
| MLLT3 | SIRT1 | Affinity Capture-MS | 20431927 | 9606 | 9606 | BIOGRID |
| MLLT3 | CCNT1 | Affinity Capture-MS | 20431927 | 9606 | 9606 | BIOGRID |
| MLLT3 | NIPBL | Affinity Capture-MS | 20431927 | 9606 | 9606 | BIOGRID |
| MLLT3 | EAF1 | Affinity Capture-MS | 20431927 | 9606 | 9606 | BIOGRID |
| MLLT3 | ELL3 | Affinity Capture-MS | 20431927 | 9606 | 9606 | BIOGRID |
| MLLT3 | PCGF1 | Affinity Capture-MS | 20431927 | 9606 | 9606 | BIOGRID |
| MLLT3 | MLLT1 | Affinity Capture-MS | 20431927 | 9606 | 9606 | BIOGRID |
| MLLT3 | EEF2 | Affinity Capture-MS | 20431927 | 9606 | 9606 | BIOGRID |
| MLLT3 | ELL | Affinity Capture-MS | 20431927 | 9606 | 9606 | BIOGRID |
| MLLT3 | BCOR | Affinity Capture-MS | 20854876 | 9606 | 9606 | BIOGRID |
| MLLT3 | DOT1L | Affinity Capture-MS | 20854876 | 9606 | 9606 | BIOGRID |
| MLLT3 | AFF1 | Affinity Capture-MS | 20854876 | 9606 | 9606 | BIOGRID |
| MLLT3 | AFF3 | Affinity Capture-MS | 20854876 | 9606 | 9606 | BIOGRID |
| MLLT3 | AFF4 | Affinity Capture-MS | 20854876 | 9606 | 9606 | BIOGRID |
| MLLT3 | MLLT10 | Affinity Capture-MS | 20854876 | 9606 | 9606 | BIOGRID |
| MLLT3 | CCNT1 | Affinity Capture-MS | 20854876 | 9606 | 9606 | BIOGRID |
| MLLT3 | CCNT2 | Affinity Capture-MS | 20854876 | 9606 | 9606 | BIOGRID |
| MLLT3 | MLLT1 | Affinity Capture-MS | 20854876 | 9606 | 9606 | BIOGRID |
| MLLT3 | ELL | Affinity Capture-MS | 20854876 | 9606 | 9606 | BIOGRID |
| MLLT3 | CDK9 | Affinity Capture-MS | 20854876 | 9606 | 9606 | BIOGRID |
| MLLT3 | RNF2 | Affinity Capture-MS | 20854876 | 9606 | 9606 | BIOGRID |
| MLLT3 | AFF3 | Affinity Capture-Western | 20854876 | 9606 | 9606 | BIOGRID |
| MLLT3 | AFF4 | Affinity Capture-Western | 20854876 | 9606 | 9606 | BIOGRID |
| MLLT3 | CDK9 | Affinity Capture-Western | 20854876 | 9606 | 9606 | BIOGRID |
| MLLT3 | DOT1L | Affinity Capture-Western | 21896721 | 9606 | 9606 | BIOGRID |
| MLLT3 | KMT2A | Affinity Capture-Western | 21896721 | 9606 | 9606 | BIOGRID |
| MLLT3 | AFF1 | Affinity Capture-Western | 21896721 | 9606 | 9606 | BIOGRID |
| MLLT3 | AFF4 | Affinity Capture-Western | 21873227 | 9606 | 9606 | BIOGRID |
| MLLT3 | CDK9 | Affinity Capture-Western | 21873227 | 9606 | 9606 | BIOGRID |
| MLLT3 | ELL2 | Affinity Capture-Western | 21873227 | 9606 | 9606 | BIOGRID |
| MLLT3 | PAF1 | Affinity Capture-Western | 21873227 | 9606 | 9606 | BIOGRID |
| MLLT3 | APP | Reconstituted Complex | 21832049 | 9606 | 9606 | BIOGRID |
| MLLT3 | ELL | Affinity Capture-Western | 21729782 | 9606 | 9606 | BIOGRID |
| MLLT3 | EAF1 | Affinity Capture-Western | 21729782 | 9606 | 9606 | BIOGRID |
| MLLT3 | CDK9 | Affinity Capture-Western | 21729782 | 9606 | 9606 | BIOGRID |
| MLLT3 | AFF4 | Affinity Capture-Western | 21729782 | 9606 | 9606 | BIOGRID |
| MLLT3 | ELL | Affinity Capture-MS | 21729782 | 9606 | 9606 | BIOGRID |
| MLLT3 | ELL2 | Affinity Capture-MS | 21729782 | 9606 | 9606 | BIOGRID |
| MLLT3 | EAF1 | Affinity Capture-MS | 21729782 | 9606 | 9606 | BIOGRID |
| MLLT3 | AFF4 | Affinity Capture-MS | 21729782 | 9606 | 9606 | BIOGRID |
| MLLT3 | AFF1 | Affinity Capture-MS | 21729782 | 9606 | 9606 | BIOGRID |
| MLLT3 | MLLT1 | Affinity Capture-MS | 21729782 | 9606 | 9606 | BIOGRID |
| MLLT3 | CDK9 | Affinity Capture-MS | 21729782 | 9606 | 9606 | BIOGRID |
| MLLT3 | CCNT1 | Affinity Capture-MS | 21729782 | 9606 | 9606 | BIOGRID |
| MLLT3 | CCNT2 | Affinity Capture-MS | 21729782 | 9606 | 9606 | BIOGRID |
| MLLT3 | HSP90B1 | Affinity Capture-MS | 20159978 | 9606 | 9606 | BIOGRID |
| MLLT3 | HSP90B1 | Reconstituted Complex | 20159978 | 9606 | 9606 | BIOGRID |
| MLLT3 | H3F3A | Co-crystal Structure | 25417107 | 9606 | 9606 | BIOGRID |
| MLLT3 | H3F3A | Affinity Capture-Western | 25417107 | 9606 | 9606 | BIOGRID |
| MLLT3 | DOT1L | Affinity Capture-Western | 25417107 | 9606 | 9606 | BIOGRID |
| MLLT3 | CDK9 | Affinity Capture-Western | 25417107 | 9606 | 9606 | BIOGRID |
| MLLT3 | ELL2 | Affinity Capture-Western | 25417107 | 9606 | 9606 | BIOGRID |
| MLLT3 | AFF4 | Affinity Capture-Western | 25417107 | 9606 | 9606 | BIOGRID |
| MLLT3 | HIST1H3A | Co-crystal Structure | 30385749 | 9606 | 9606 | BIOGRID |
| MLLT3 | HIST1H3A | Reconstituted Complex | 30385749 | 9606 | 9606 | BIOGRID |
| MLLT3 | ZNF572 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| MLLT3 | FAM9A | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| MLLT3 | HHT1 | Reconstituted Complex | 29145630 | 9606 | 559292 | BIOGRID |
Annotation of MLLT3
TCGA cancer survival map of MLLT3
Expression of MLLT3
Disease information of MLLT3