1. Home
  2. Browse TcoF of biosample
TcoF overview
TcoF: NOTCH3
GeneID: 4999
Name: Neurogenic locus notch homolog protein 3
Ensembl: ENSG00000074181
Species: Human
Class: class 2
Family: Notch
Disease: 24
Go term: 27
Pathway: 21
Hallmark: 1
Super Enhancer:

chr19:15333113-15371771 chr19:15305089-15321864 chr19:15280442-15337327 chr19:15305789-15314084 chr19:15305637-15335203 chr19:15304754-15313088 chr19:15304888-15335050 chr19:15307905-15335520
Enhancer:

chr19:15223380-15224370 chr19:15235880-15236460 chr19:15296490-15297680 chr19:15297800-15297910 chr19:15234390-15235730 chr19:15374360-15375210 chr19:15376460-15378220 chr19:15218330-15219860 chr19:15231120-15233500 chr19:15233620-15233700 chr19:15342210-15342580 chr19:15342670-15342770 chr19:15378360-15379710 chr19:15514850-15516650 chr19:15288900-15289270 chr19:15375580-15376160 chr19:15350830-15352750 chr19:15228830-15229970 chr19:15516770-15517060 chr19:14869080-14870640 chr19:14978290-14980560 chr19:15222600-15223150 chr19:15279410-15280890 chr19:15280980-15281140 chr19:15281360-15281480 chr19:15089140-15090320 chr19:15305670-15307600 chr19:15388820-15391070 chr19:15411470-15412180 chr19:15412720-15413480 chr19:15413790-15416270 chr19:15434040-15436520 chr19:15436730-15438760 chr19:15527280-15529720 chr19:15547940-15549550 chr19:15147950-15149920 chr19:15320210-15322550 chr19:15386660-15388810 chr19:15444530-15445060 chr19:15538350-15539280 chr19:15539510-15540060 chr19:15540070-15540240 chr19:15560420-15560600 chr19:15567460-15568100 chr19:15299160-15299790 chr19:15300240-15301540 chr19:16197350-16198830 chr19:15421330-15422400 chr19:15422650-15423140 chr19:15424340-15426710 chr19:15439120-15439910 chr19:15478510-15479040 chr19:15479130-15480950 chr19:15484880-15485410 chr19:15512420-15514280 chr19:15514530-15514820 chr19:15384920-15385790 chr19:15385940-15386600 chr19:15526880-15527270 chr19:15477790-15478500 chr19:15523530-15525210 chr19:15355570-15357840 chr19:15469870-15471650 chr19:15553940-15555360 chr19:15341900-15342040 chr19:15355460-15355520 chr19:15365070-15365240 chr19:15509580-15510110 chr19:15510220-15511100 chr19:15511860-15511960 chr19:15519930-15521330 chr19:15226240-15226370 chr19:15226480-15226660 chr19:15751760-15752220

Promoter:

chr19:15269849-15311806

 ChIP-seq based regulatory details of NOTCH3
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
TcoF_00_21199 NOTCH3 cell line None GSM2793827 None Cistrome
TcoF_00_40608 NOTCH3 cell line TALL-1_DMSO GSM2793827 None ReMap
TcoF_00_21198 NOTCH3 cell line None GSM2793828 None Cistrome
TcoF_00_40609 NOTCH3 cell line TALL-1_GSI GSM2793828 None ReMap
 Downstream target genes of NOTCH3
 Upstream regulatory details of NOTCH3
 Protein-protein interaction of NOTCH3
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
NOTCH3 SNW1 Reconstituted Complex 11404076 9606 9606 BIOGRID
NOTCH3 DLL1 Reconstituted Complex 11006133 9606 9606 BIOGRID
NOTCH3 JAG1 Reconstituted Complex 11006133 9606 9606 BIOGRID
NOTCH3 JAG2 Reconstituted Complex 11006133 9606 9606 BIOGRID
NOTCH3 GSK3B Affinity Capture-Western 21502811 9606 9606 BIOGRID
NOTCH3 STRAP Affinity Capture-Western 21502811 9606 9606 BIOGRID
NOTCH3 CBL Affinity Capture-Western 19966856 9606 9606 BIOGRID
NOTCH3 MPPED2 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 GGT6 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 CBFA2T2 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 SPTLC2 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 RET Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 MYC Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 SORBS3 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 WWP2 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 RBPJ Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 TNNT2 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 XKR8 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 SNX19 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 CNTD1 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 WDR25 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 SCGB3A1 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 CPNE6 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 BAG2 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 SLC39A1 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 PPIA Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 C8orf76 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 C1QL1 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 TMEM108 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 NEDD9 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 RMI2 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 CRIP2 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 BTF3L4 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 TPT1 Reconstituted Complex 25356737 9606 9606 BIOGRID
NOTCH3 CASR Affinity Capture-Western 17573339 9606 9606 BIOGRID
NOTCH3 PRR20B Two-hybrid 32296183 9606 9606 BIOGRID
NOTCH3 PRR20A Two-hybrid 32296183 9606 9606 BIOGRID
NOTCH3 PRR20D Two-hybrid 32296183 9606 9606 BIOGRID
NOTCH3 PRR20C Two-hybrid 32296183 9606 9606 BIOGRID
NOTCH3 PRR20E Two-hybrid 32296183 9606 9606 BIOGRID
NOTCH3 LTBP1 Reconstituted Complex 25190493 9606 9606 BIOGRID
 Annotation of NOTCH3
 TCGA cancer survival map of NOTCH3


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Expression of  NOTCH3
 Disease information of  NOTCH3