TcoF overview
| TcoF: | PDPK1 | |
| GeneID: | 10401 | |
| Name: | Non-specific serine/threonine protein kinase | |
| Ensembl: | ENSG00000140992 | |
| Species: | Human | |
| Class: | class 3 | |
| Family: | Others | |
| Disease: | 13 | |
| Go term: | 53 | |
| Pathway: | 77 | |
| Hallmark: | 4 | |
| Super Enhancer: |
chr16:2602202-2611752 chr16:2584725-2612047 chr16:2584703-2611962 chr16:2597841-2620122 chr16:2584977-2593875 chr16:2591355-2642323 chr16:2584933-2611783 chr16:2584779-2611672 chr16:2589708-2631581 chr16:2596580-2607922 chr16:2580578-2591458 chr16:2580941-2612050 |
|
| Enhancer: |
chr16:1991410-1993100 chr16:2009760-2010000 chr16:2022210-2024050 chr16:2040200-2041970 chr16:2089030-2089810 chr16:2127730-2129030 chr16:2135320-2136190 chr16:2136380-2136730 chr16:2147990-2149640 chr16:2150070-2150160 chr16:2150310-2150390 chr16:2150570-2152060 chr16:2152970-2153260 chr16:2153900-2154490 chr16:2154640-2155320 chr16:2155480-2155860 chr16:2198980-2199940 chr16:2200050-2200800 chr16:2214000-2215870 chr16:2222600-2223180 chr16:2223400-2223480 chr16:2223560-2223780 chr16:2224050-2224250 chr16:2255880-2256030 chr16:2288710-2289870 chr16:2301430-2301510 chr16:2458300-2460170 chr16:2479500-2481130 chr16:2564180-2565360 chr16:2570540-2570760 chr16:2819290-2820350 chr16:2827130-2827230 chr16:2867970-2868670 chr16:2904020-2905570 chr16:2962160-2964170 chr16:2983580-2983710 chr16:3021380-3021510 chr16:3023490-3024000 chr16:3024160-3024240 chr16:3024420-3024550 chr16:3029940-3030280 chr16:3105950-3107030 chr16:2472770-2474400 chr16:2980880-2982490 chr16:2256220-2256350 chr16:2256410-2256490 chr16:2286560-2286770 chr16:2415810-2416960 chr16:2825560-2826990 chr16:2145290-2146620 chr16:2722570-2723280 chr16:2849570-2850790 chr16:2077220-2078260 chr16:2136870-2137860 chr16:2427910-2429420 chr16:2487320-2488070 chr16:2488120-2488780 chr16:2570910-2570980 chr16:2867330-2867430 chr16:2867450-2867800 chr16:2880330-2880410 chr16:2880500-2880690 chr16:2980010-2980410 chr16:3019840-3021160 chr16:3097020-3097410 chr16:3097550-3100000 chr16:3100150-3100250 chr16:3105030-3105730 chr16:3108340-3108410 chr16:3162950-3163340 chr16:3179310-3179460 chr16:3179660-3180060 chr16:1990890-1991250 chr16:2485880-2487120 chr16:2489830-2490390 chr16:2223830-2223920 chr16:2460450-2460620 chr16:2514230-2514520 chr16:2421940-2423950 chr16:2525170-2527400 chr16:2547120-2547710 chr16:2547720-2548230 chr16:2752480-2754800 chr16:2183210-2185470 chr16:2224340-2225110 chr16:2571120-2572260 chr16:2732800-2734550 chr16:2933370-2935400 chr16:2226390-2226560 chr16:2279680-2281470 chr16:2548400-2549350 chr16:2549420-2549830 chr16:2549930-2550260 chr16:2764340-2765710 chr16:2818260-2818990 chr16:2417130-2419300 chr16:2344080-2345590 chr16:2385560-2385920 chr16:3107620-3108180 chr16:2228650-2228900 chr16:2299150-2301310 chr16:2656340-2658590 chr16:1989140-1990770 chr16:2003040-2003950 chr16:2004150-2004520 chr16:2152640-2152810 chr16:2156310-2156390 chr16:2235410-2236700 chr16:2236830-2236970 chr16:2237070-2237160 chr16:2237280-2237350 chr16:2237460-2239020 chr16:2256660-2257030 chr16:2286960-2287030 chr16:2287130-2287210 chr16:2287650-2287760 chr16:2294550-2296850 chr16:2345740-2347320 chr16:2514960-2516490 chr16:2905850-2906080 chr16:2906840-2908020 chr16:2053120-2053610 chr16:2257110-2257190 chr16:2257350-2258210 chr16:2258340-2258450 chr16:2258620-2258750 chr16:2259460-2259550 chr16:2259710-2259950 chr16:2260050-2260120 chr16:2260280-2260520 chr16:2260650-2260780 chr16:2287300-2287370 chr16:2288020-2288360 chr16:2293230-2293310 chr16:2820470-2820600 chr16:2820720-2820850 chr16:3024660-3025310 chr16:3025810-3026660 chr16:3100550-3102120 chr16:2293440-2294400 chr16:2835650-2835790 chr16:2835960-2836080 chr16:2836120-2836500 chr16:2906260-2906820 chr16:2945480-2946350 chr16:2784530-2786780 chr16:2070760-2071860 chr16:2086500-2086720 chr16:2231600-2231790 chr16:2231930-2233640 chr16:2550490-2550800 chr16:2579730-2580030 chr16:2042210-2042630 chr16:2045590-2047650 chr16:2173690-2174000 chr16:2174310-2176000 chr16:2176860-2178120 chr16:2824150-2824710 chr16:2964290-2966590 chr16:2940200-2942070 chr16:2240350-2240740 chr16:2398670-2399460 chr16:2974410-2974920 chr16:2365150-2366940 chr16:2483070-2484130 chr16:2496980-2498850 chr16:2659780-2660440 chr16:2713410-2714940 chr16:2715170-2716760 chr16:2763700-2764060 chr16:2885050-2887540 chr16:3082740-3084120 chr16:2768460-2770110 chr16:2086990-2087530 chr16:2447470-2448890 chr16:2482320-2482960 chr16:2765880-2766500 chr16:2413890-2415680 chr16:2503540-2505120 chr16:2825360-2825450 chr16:2052730-2052990 chr16:2090050-2090130 chr16:2104440-2105400 chr16:2105520-2105620 chr16:2130820-2131590 chr16:2131800-2132430 chr16:2132510-2133690 chr16:2133820-2134220 chr16:2134720-2134950 chr16:2577620-2577770 chr16:2577990-2578060 chr16:2578150-2578230 chr16:2578380-2578450 chr16:2578720-2578990 chr16:2579100-2579470 chr16:1949640-1951320 chr16:2163290-2164170 chr16:1808160-1808690 chr16:2056360-2056620 chr16:2124390-2125790 chr16:2135030-2135230 chr16:2137940-2138040 chr16:2138140-2138220 chr16:2138330-2138440 chr16:2170520-2172900 chr16:2576020-2577560 chr16:3177230-3179240 chr16:3103620-3104940 chr16:2573030-2575370 chr16:2644890-2645790 chr16:2739850-2741630 chr16:2983980-2984320 chr16:2984570-2984930 chr16:2985090-2986570 chr16:2653730-2655710 chr16:2350150-2350950 chr16:3041440-3042400 chr16:2849130-2849280 chr16:1797280-1798240 chr16:1811380-1812350 chr16:1812480-1812670 chr16:1812730-1812830 chr16:2024100-2024190 chr16:2051190-2051580 chr16:2051700-2052200 chr16:2052420-2052520 chr16:2086880-2086950 chr16:2278520-2279570 chr16:2324690-2325870 chr16:2611520-2611770 |
|
| Promoter: |
chr16:2587980-2653189 |
ChIP-seq based regulatory details of PDPK1
| Sample ID | Experiment target | Biosample type | Biosample term name | GSM ID | Tissue type | Source |
|---|
Downstream target genes of PDPK1
Upstream regulatory details of PDPK1
Protein-protein interaction of PDPK1
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| PDPK1 | PRKCZ | Two-hybrid | 10764742 | 9606 | 9606 | BIOGRID |
| PDPK1 | PRKCI | Two-hybrid | 10764742 | 9606 | 9606 | BIOGRID |
| PDPK1 | SLC9A3R2 | Affinity Capture-Western | 12387817 | 9606 | 9606 | BIOGRID |
| PDPK1 | PRKCD | Affinity Capture-Western | 11781095 | 9606 | 9606 | BIOGRID |
| PDPK1 | PRKCZ | Affinity Capture-Western | 11781095 | 9606 | 9606 | BIOGRID |
| PDPK1 | PKN2 | Affinity Capture-Western | 11781095 | 9606 | 9606 | BIOGRID |
| PDPK1 | PDPK1 | Biochemical Activity | 10856237 | 9606 | 9606 | BIOGRID |
| PDPK1 | AKT1 | Affinity Capture-Western | 11825911 | 9606 | 9606 | BIOGRID |
| PDPK1 | PRKCB | Reconstituted Complex | 11376011 | 9606 | 9606 | BIOGRID |
| PDPK1 | PRKCZ | Biochemical Activity | 9748166 | 9606 | 9606 | BIOGRID |
| PDPK1 | PRKCZ | Affinity Capture-Western | 9748166 | 9606 | 9606 | BIOGRID |
| PDPK1 | PKN2 | Two-hybrid | 10764742 | 9606 | 9606 | BIOGRID |
| PDPK1 | PKN1 | Two-hybrid | 10764742 | 9606 | 9606 | BIOGRID |
| PDPK1 | YWHAQ | Affinity Capture-Western | 12177059 | 9606 | 9606 | BIOGRID |
| PDPK1 | YWHAH | Affinity Capture-Western | 12177059 | 9606 | 9606 | BIOGRID |
| PDPK1 | PRKACA | Two-hybrid | 10698939 | 9606 | 9606 | BIOGRID |
| PDPK1 | ILK | Affinity Capture-Western | 11313365 | 9606 | 9606 | BIOGRID |
| PDPK1 | SGK1 | Reconstituted Complex | 10357815 | 9606 | 9606 | BIOGRID |
| PDPK1 | MAPK8 | Reconstituted Complex | 10357815 | 9606 | 9606 | BIOGRID |
| PDPK1 | PRKCZ | Reconstituted Complex | 10357815 | 9606 | 9606 | BIOGRID |
| PDPK1 | SND1 | Affinity Capture-MS | 20562859 | 9606 | 9606 | BIOGRID |
| PDPK1 | G3BP1 | Affinity Capture-MS | 20562859 | 9606 | 9606 | BIOGRID |
| PDPK1 | TBL2 | Affinity Capture-MS | 20562859 | 9606 | 9606 | BIOGRID |
| PDPK1 | PA2G4 | Affinity Capture-MS | 20562859 | 9606 | 9606 | BIOGRID |
| PDPK1 | PRKCQ | Affinity Capture-Western | 15802604 | 9606 | 9606 | BIOGRID |
| PDPK1 | CARD11 | Affinity Capture-Western | 15802604 | 9606 | 9606 | BIOGRID |
| PDPK1 | PEA15 | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | FAM213B | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | CARD11 | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | POLDIP2 | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | GIT1 | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | ZNF133 | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | XPO7 | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | SBF1 | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | PNO1 | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | DDIT4 | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | SMARCB1 | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | SOCS3 | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | C2orf44 | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | KATNBL1 | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | XRCC6 | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | TCAP | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | BLMH | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | PHAX | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | ZC3HC1 | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | LUC7L2 | Two-hybrid | 21900206 | 9606 | 9606 | BIOGRID |
| PDPK1 | SGK1 | Biochemical Activity | 17916563 | 9606 | 9606 | BIOGRID |
| PDPK1 | STRAP | Affinity Capture-Western | 17916563 | 9606 | 9606 | BIOGRID |
| PDPK1 | APP | Reconstituted Complex | 21832049 | 9606 | 9606 | BIOGRID |
| PDPK1 | AKT1 | Biochemical Activity | 22569334 | 9606 | 9606 | BIOGRID |
| PDPK1 | PDPK1 | Biochemical Activity | 25384981 | 9606 | 9606 | BIOGRID |
| PDPK1 | TBL2 | Affinity Capture-MS | 26186194 | 9606 | 9606 | BIOGRID |
| PDPK1 | SERPINA4 | Affinity Capture-MS | 26186194 | 9606 | 9606 | BIOGRID |
| PDPK1 | CPA4 | Affinity Capture-MS | 26186194 | 9606 | 9606 | BIOGRID |
| PDPK1 | FAM199X | Affinity Capture-MS | 26186194 | 9606 | 9606 | BIOGRID |
| PDPK1 | MAP3K7 | Affinity Capture-Western | 26432169 | 9606 | 9606 | BIOGRID |
| PDPK1 | HSPA8 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| PDPK1 | SERPINA4 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| PDPK1 | FAM199X | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| PDPK1 | SCRN2 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| PDPK1 | CPA4 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| PDPK1 | TBL2 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| PDPK1 | AKT2 | Affinity Capture-Western | 27563096 | 9606 | 9606 | BIOGRID |
| PDPK1 | AKT1 | Affinity Capture-Western | 27563096 | 9606 | 9606 | BIOGRID |
| PDPK1 | AKAP12 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | CDC37 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | HSPA9 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | HSPA6 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | HSPA8 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | HSPA1A | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | YWHAG | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | YWHAB | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | JUP | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | OSBPL8 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | GLG1 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | YWHAH | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | YWHAZ | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | SFN | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | HSPA5 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | HSPH1 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | IQGAP1 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | TMEM161A | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | USP7 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | HSPA4 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | LRPPRC | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | GRPEL1 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | POLRMT | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | DDX24 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | SNX18 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | CHD4 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | SQSTM1 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | ASPH | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | PRPF31 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | RPL38 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | GTF3C5 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | TMED7-TICAM2 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | ACOT9 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | TCF25 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | SLC29A1 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | LRRC59 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | TBC1D15 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | PTRF | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | FLNC | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | MTA1 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | CHAF1B | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | DHX9 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | HSPG2 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | GTF2I | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | HADHB | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | LOC400927-CSNK1E | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | CSNK1D | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | HADHA | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | GPC1 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | UQCRC1 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | SDC4 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | POLR2A | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | UQCRC2 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | SDC1 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | CD44 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | FGF2 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | GPC4 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | ROCK2 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | PDPK1 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | AGRN | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | CAMSAP3 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | ARPC5 | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | PRKCI | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | YWHAE | Affinity Capture-MS | 31980649 | 9606 | 9606 | BIOGRID |
| PDPK1 | Akt1 | Biochemical Activity | 19662498 | 9606 | 10090 | BIOGRID |
Annotation of PDPK1
TCGA cancer survival map of PDPK1
Expression of PDPK1
Disease information of PDPK1