TcoF overview
TcoF: PRMT5
GeneID: 5702
Name: Protein arginine N-methyltransferase 5
Ensembl: ENSG00000100462
Species: Human
Class: class 2
Family: Arginine methyltransferase
Disease: 0
Go term: 37
Pathway: 8
Hallmark: --
Super Enhancer:

chr14:23386026-23406459

--
Enhancer:

chr14:23070660-23072290 chr14:23235970-23236460 chr14:23294020-23294090 chr14:23341550-23341940 chr14:23341990-23342510 chr14:23352600-23353880 chr14:23424390-23426120 chr14:23442780-23443250 chr14:23468610-23470160 chr14:23525070-23526610 chr14:23540400-23540630 chr14:23791030-23791380 chr14:23791500-23792200 chr14:23237380-23238990 chr14:23299320-23299390 chr14:23502880-23503890 chr14:23531750-23532130 chr14:23547480-23548020 chr14:23548250-23548750 chr14:23768750-23769960 chr14:23770070-23770500 chr14:23777410-23778020 chr14:23707260-23709550 chr14:23299460-23300170 chr14:23236620-23237160 chr14:23282650-23284520 chr14:23355440-23355820 chr14:23377580-23378690 chr14:23420900-23421530 chr14:23587030-23587790 chr14:23938940-23939250 chr14:23939310-23940110 chr14:23300250-23300740 chr14:23538830-23540330 chr14:23524560-23524740 chr14:23621100-23623460 chr14:23649320-23650040 chr14:23650770-23651970 chr14:23752700-23755120 chr14:23819660-23820960 chr14:23821060-23821150 chr14:23363960-23366460 chr14:23642860-23644700 chr14:23982540-23983440 chr14:23983630-23984100 chr14:23987580-23990060 chr14:24017360-24018480 chr14:24019140-24020190 chr14:22986200-22987640 chr14:23984660-23986290 chr14:23371590-23373460 chr14:23466010-23466850 chr14:23532790-23533310 chr14:23354220-23354470 chr14:23354550-23355230 chr14:23445730-23445850 chr14:23444310-23445660 chr14:23609830-23612280 chr14:23768130-23768600 chr14:23848980-23851190 chr14:24031800-24032580 chr14:23245530-23248000 chr14:22933410-22934290 chr14:22947180-22949380 chr14:22950960-22952870 chr14:22974060-22975230 chr14:22979120-22980210 chr14:22984160-22984870 chr14:22984950-22985810 chr14:22988490-22990040 chr14:22993010-22994110 chr14:22994740-22995420 chr14:23055410-23057850 chr14:23205680-23207890 chr14:23260180-23261140 chr14:23262820-23264750 chr14:23272630-23273130 chr14:23356890-23359040 chr14:23264830-23267310 chr14:23279650-23282100 chr14:23326390-23328770 chr14:23376450-23377490 chr14:23518480-23518830 chr14:23545780-23547350 chr14:23550020-23550950 chr14:23607230-23608630 chr14:23829490-23829760 chr14:24033070-24033250 chr14:23239140-23239400 chr14:23239490-23239660 chr14:23239840-23240010 chr14:23240390-23240470 chr14:23240560-23240640 chr14:23241000-23241550 chr14:23241650-23242430 chr14:23242930-23243140 chr14:23243330-23243560 chr14:23243710-23244650 chr14:23334020-23335950 chr14:23370940-23371020 chr14:23371090-23371180 chr14:23371310-23371390 chr14:23373540-23374080 chr14:23374220-23374300 chr14:23374860-23375400 chr14:23443320-23444040 chr14:23444090-23444180 chr14:23495580-23496490 chr14:23519150-23521170 chr14:23521290-23521680 chr14:23521820-23522700 chr14:23523880-23523950 chr14:23532280-23532640 chr14:23533700-23535170 chr14:23738170-23739070 chr14:23792280-23792580 chr14:23792690-23793170 chr14:23793260-23793340 chr14:23793500-23794450 chr14:23827120-23828080 chr14:23947400-23949400 chr14:23997170-23998910 chr14:24031080-24031170 chr14:24031280-24031490 chr14:24031620-24031710 chr14:24032850-24032920 chr14:24033430-24033540 chr14:24033600-24033770 chr14:24034050-24034320 chr14:24034410-24034660 chr14:24042050-24043860 chr14:24108570-24109000 chr14:24114090-24114350 chr14:23903460-23904820 chr14:23854250-23855130 chr14:23040710-23043170 chr14:23081280-23081670 chr14:23082060-23083810 chr14:23090870-23091680 chr14:23158380-23159100 chr14:23159960-23161750 chr14:23306140-23308360 chr14:23614580-23616730 chr14:23640050-23642060 chr14:23644810-23645680 chr14:23091980-23092390 chr14:23551050-23552570 chr14:23599010-23600660 chr14:23646180-23647920 chr14:23686110-23687340 chr14:23721050-23722450 chr14:23492990-23495050 chr14:23593820-23594420 chr14:23597570-23598850 chr14:23604910-23607120 chr14:23618510-23618950 chr14:23619340-23619800 chr14:23922680-23924430 chr14:23075440-23077490 chr14:23559310-23559680 chr14:23310860-23311080 chr14:23311240-23311540 chr14:23311930-23312160 chr14:23312250-23312460 chr14:22836240-22838040 chr14:22859340-22859890 chr14:22900880-22902780 chr14:23612410-23613540 chr14:22739740-22740700 chr14:22757520-22758460 chr14:22846120-22847040 chr14:22880600-22882000 chr14:22882160-22884520 chr14:22894990-22897450 chr14:22897540-22899420 chr14:23044700-23046520 chr14:23046640-23048440 chr14:23168110-23170450 chr14:23209490-23211660 chr14:23249260-23251400 chr14:23276340-23277410 chr14:23489430-23491770 chr14:23573600-23575140 chr14:23749040-23749910 chr14:23962540-23964820 chr14:24013510-24015230 chr14:22952940-22954110 chr14:23575690-23577540 chr14:23899120-23899760 chr14:23899870-23900100 chr14:23900210-23900620 chr14:23999400-24000680 chr14:23316810-23319220 chr14:23170670-23173130

--
Promoter:

chr14:23389734-23398617

False
 ChIP-seq based regulatory details of PRMT5
select * from encode where Experiment_target='PRMT5'
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
TcoF_00_20002 PRMT5 cell line MDA-MB-231 GSM1964895 Breast Cistrome
 Downstream target genes of PRMT5
 Protein-protein interaction of PRMT5
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
PRMT5 CLNS1A Two-hybrid 9556550 9606 9606 BIOGRID
PRMT5 SUPT5H Biochemical Activity 12718890 9606 9606 BIOGRID
PRMT5 PRMT5 Affinity Capture-Western 11152681 9606 9606 BIOGRID
PRMT5 MBP Biochemical Activity 11152681 9606 9606 BIOGRID
PRMT5 JAK1 Reconstituted Complex 10531356 9606 9606 BIOGRID
PRMT5 JAK2 Reconstituted Complex 10531356 9606 9606 BIOGRID
PRMT5 JAK3 Reconstituted Complex 10531356 9606 9606 BIOGRID
PRMT5 TYK2 Reconstituted Complex 10531356 9606 9606 BIOGRID
PRMT5 PRMT5 Affinity Capture-Western 10531356 9606 9606 BIOGRID
PRMT5 CLNS1A Affinity Capture-MS 11756452 9606 9606 BIOGRID
PRMT5 WDR77 Affinity Capture-MS 11756452 9606 9606 BIOGRID
PRMT5 CLNS1A Affinity Capture-Western 11756452 9606 9606 BIOGRID
PRMT5 WDR77 Affinity Capture-Western 11756452 9606 9606 BIOGRID
PRMT5 CLNS1A Reconstituted Complex 11756452 9606 9606 BIOGRID
PRMT5 WDR77 Reconstituted Complex 11756452 9606 9606 BIOGRID
PRMT5 PRDM1 Affinity Capture-Western 18992153 9606 9606 BIOGRID
PRMT5 DNMT3A Reconstituted Complex 19234465 9606 9606 BIOGRID
PRMT5 MEF2D Reconstituted Complex 19188441 9606 9606 BIOGRID
PRMT5 MYOD1 Reconstituted Complex 19188441 9606 9606 BIOGRID
PRMT5 MYOG Reconstituted Complex 19188441 9606 9606 BIOGRID
PRMT5 ZNF224 Affinity Capture-Western 19741270 9606 9606 BIOGRID
PRMT5 CLNS1A Reconstituted Complex 19520849 9606 9606 BIOGRID
PRMT5 MBD2 Affinity Capture-Western 16428440 9606 9606 BIOGRID
PRMT5 SMARCA4 Affinity Capture-Western 14559996 9606 9606 BIOGRID
PRMT5 SMARCA2 Affinity Capture-Western 14559996 9606 9606 BIOGRID
PRMT5 SIN3A Affinity Capture-Western 14559996 9606 9606 BIOGRID
PRMT5 SMARCA4 Reconstituted Complex 14559996 9606 9606 BIOGRID
PRMT5 SMARCA2 Reconstituted Complex 14559996 9606 9606 BIOGRID
PRMT5 SIN3A Reconstituted Complex 14559996 9606 9606 BIOGRID
PRMT5 SMARCE1 Reconstituted Complex 14559996 9606 9606 BIOGRID
PRMT5 SMARCB1 Reconstituted Complex 14559996 9606 9606 BIOGRID
PRMT5 HIST1H3A Biochemical Activity 14559996 9606 9606 BIOGRID
PRMT5 HIST1H4A Biochemical Activity 14559996 9606 9606 BIOGRID
PRMT5 CTDP1 Affinity Capture-Western 15670829 9606 9606 BIOGRID
PRMT5 HIST1H4A Biochemical Activity 15670829 9606 9606 BIOGRID
PRMT5 HIST2H2AC Biochemical Activity 15670829 9606 9606 BIOGRID
PRMT5 HIST1H3A Biochemical Activity 15670829 9606 9606 BIOGRID
PRMT5 AJUBA Affinity Capture-Western 18347060 9606 9606 BIOGRID
PRMT5 HIST1H3A Biochemical Activity 15485929 9606 9606 BIOGRID
PRMT5 HIST1H4A Biochemical Activity 15485929 9606 9606 BIOGRID
PRMT5 JAK2 Affinity Capture-Western 21316606 9606 9606 BIOGRID
PRMT5 CCND1 Affinity Capture-Western 20951943 9606 9606 BIOGRID
PRMT5 CDK4 Affinity Capture-Western 20951943 9606 9606 BIOGRID
PRMT5 SMARCA4 Affinity Capture-Western 20951943 9606 9606 BIOGRID
PRMT5 WDR77 Affinity Capture-Western 20951943 9606 9606 BIOGRID
PRMT5 SNRPB Reconstituted Complex 17709427 9606 9606 BIOGRID
PRMT5 HIST1H3A Biochemical Activity 22231400 9606 9606 BIOGRID
PRMT5 WDR77 Affinity Capture-Western 22169276 9606 9606 BIOGRID
PRMT5 HOXA9 Affinity Capture-Western 22269951 9606 9606 BIOGRID
PRMT5 DST Co-fractionation 22939629 9606 9606 BIOGRID
PRMT5 SNRNP70 Two-hybrid 22365833 9606 9606 BIOGRID
PRMT5 SF3A3 Two-hybrid 22365833 9606 9606 BIOGRID
PRMT5 RBM23 Two-hybrid 22365833 9606 9606 BIOGRID
PRMT5 CCAR2 Two-hybrid 22365833 9606 9606 BIOGRID
PRMT5 ARGLU1 Two-hybrid 22365833 9606 9606 BIOGRID
PRMT5 PRMT5 Two-hybrid 22365833 9606 9606 BIOGRID
PRMT5 WDR77 Two-hybrid 22365833 9606 9606 BIOGRID
PRMT5 CLNS1A Two-hybrid 22365833 9606 9606 BIOGRID
PRMT5 WDR77 Co-purification 23071334 9606 9606 BIOGRID
PRMT5 PRMT5 Co-purification 23071334 9606 9606 BIOGRID
PRMT5 RELA Affinity Capture-Western 23904475 9606 9606 BIOGRID
PRMT5 COPS4 Co-fractionation 22863883 9606 9606 BIOGRID
PRMT5 VASP Co-fractionation 22863883 9606 9606 BIOGRID
PRMT5 WDR5 Affinity Capture-Western 22689669 9606 9606 BIOGRID
PRMT5 WDR5 Reconstituted Complex 22689669 9606 9606 BIOGRID
PRMT5 WDR5 Co-fractionation 22689669 9606 9606 BIOGRID
PRMT5 ING2 Co-fractionation 22689669 9606 9606 BIOGRID
PRMT5 CTPS1 Co-fractionation 26344197 9606 9606 BIOGRID
PRMT5 DYNC1H1 Co-fractionation 26344197 9606 9606 BIOGRID
PRMT5 EIF2S1 Co-fractionation 26344197 9606 9606 BIOGRID
PRMT5 NCBP1 Co-fractionation 26344197 9606 9606 BIOGRID
PRMT5 NSFL1C Co-fractionation 26344197 9606 9606 BIOGRID
PRMT5 PDCD4 Co-fractionation 26344197 9606 9606 BIOGRID
PRMT5 PDIA6 Co-fractionation 26344197 9606 9606 BIOGRID
PRMT5 RRP12 Co-fractionation 26344197 9606 9606 BIOGRID
PRMT5 SBNO1 Co-fractionation 26344197 9606 9606 BIOGRID
PRMT5 WDR77 Co-fractionation 26344197 9606 9606 BIOGRID
PRMT5 WDR77 Two-hybrid 18404153 9606 9606 BIOGRID
PRMT5 COPRS Two-hybrid 18404153 9606 9606 BIOGRID
PRMT5 HIST4H4 Biochemical Activity 18404153 9606 9606 BIOGRID
PRMT5 HIST4H4 Biochemical Activity 25713080 9606 9606 BIOGRID
PRMT5 CDK8 Affinity Capture-Western 23749998 9606 9606 BIOGRID
PRMT5 CDK19 Affinity Capture-Western 23749998 9606 9606 BIOGRID
PRMT5 TRAF4 Affinity Capture-Western 25704480 9606 9606 BIOGRID
PRMT5 RELA Affinity Capture-Western 25704480 9606 9606 BIOGRID
PRMT5 SREBF1 Affinity Capture-MS 26759235 9606 9606 BIOGRID
PRMT5 SREBF1 Affinity Capture-Western 26759235 9606 9606 BIOGRID
PRMT5 SREBF1 Biochemical Activity 26759235 9606 9606 BIOGRID
PRMT5 STUB1 Affinity Capture-MS 26658161 9606 9606 BIOGRID
PRMT5 TRIM21 Affinity Capture-MS 26658161 9606 9606 BIOGRID
PRMT5 RANBP2 Affinity Capture-MS 26658161 9606 9606 BIOGRID
PRMT5 STUB1 Affinity Capture-Western 26658161 9606 9606 BIOGRID
PRMT5 STUB1 PCA 26658161 9606 9606 BIOGRID
PRMT5 POLR2A Biochemical Activity 26700805 9606 9606 BIOGRID
PRMT5 UHRF1 Affinity Capture-Western 26597461 9606 9606 BIOGRID
PRMT5 RPL23 Positive Genetic 30033366 9606 9606 BIOGRID
PRMT5 UBA2 Negative Genetic 30033366 9606 9606 BIOGRID
PRMT5 ZNHIT6 Negative Genetic 30033366 9606 9606 BIOGRID
PRMT5 PRMT5 Negative Genetic 26864203 9606 9606 BIOGRID
PRMT5 HDAC1 Negative Genetic 26864203 9606 9606 BIOGRID
PRMT5 EZH1 Negative Genetic 26864203 9606 9606 BIOGRID
PRMT5 EP300 Negative Genetic 26864203 9606 9606 BIOGRID
PRMT5 DNMT1 Negative Genetic 26864203 9606 9606 BIOGRID
PRMT5 MBD1 Negative Genetic 26864203 9606 9606 BIOGRID
PRMT5 CARM1 Negative Genetic 26864203 9606 9606 BIOGRID
PRMT5 SHARPIN Affinity Capture-Western 29227283 9606 9606 BIOGRID
PRMT5 HIST1H4A Biochemical Activity 29227283 9606 9606 BIOGRID
PRMT5 ZNF326 Affinity Capture-Western 28977470 9606 9606 BIOGRID
PRMT5 WDR77 Affinity Capture-Western 28977470 9606 9606 BIOGRID
PRMT5 HNRNPH1 Affinity Capture-Western 28977470 9606 9606 BIOGRID
PRMT5 CLNS1A Affinity Capture-MS 21081503 9606 9606 BIOGRID
PRMT5 WDR77 Affinity Capture-MS 21081503 9606 9606 BIOGRID
PRMT5 RIOK1 Affinity Capture-MS 21081503 9606 9606 BIOGRID
PRMT5 RIOK1 Affinity Capture-Western 21081503 9606 9606 BIOGRID
PRMT5 CLNS1A Affinity Capture-Western 21081503 9606 9606 BIOGRID
PRMT5 WDR77 Affinity Capture-Western 21081503 9606 9606 BIOGRID
PRMT5 RIOK1 Reconstituted Complex 21081503 9606 9606 BIOGRID
PRMT5 NCL Biochemical Activity 21081503 9606 9606 BIOGRID
PRMT5 SNRPD1 Biochemical Activity 21081503 9606 9606 BIOGRID
PRMT5 ILF3 Biochemical Activity 21081503 9606 9606 BIOGRID
PRMT5 DUSP14 Affinity Capture-Western 29920217 9606 9606 BIOGRID
PRMT5 DUSP14 FRET 29920217 9606 9606 BIOGRID
PRMT5 DUSP14 Co-localization 29920217 9606 9606 BIOGRID
PRMT5 DUSP14 Biochemical Activity 29920217 9606 9606 BIOGRID
PRMT5 WDR77 Co-crystal Structure 29518110 9606 9606 BIOGRID
PRMT5 PDGFRA Affinity Capture-Western 30057274 9606 9606 BIOGRID
PRMT5 PDGFRA Biochemical Activity 30057274 9606 9606 BIOGRID
PRMT5 PHF1 Affinity Capture-Western 29846670 9606 9606 BIOGRID
PRMT5 CUL4B Co-localization 29846670 9606 9606 BIOGRID
PRMT5 DDB1 Co-localization 29846670 9606 9606 BIOGRID
PRMT5 WDR77 Co-localization 29846670 9606 9606 BIOGRID
PRMT5 PHF1 Co-localization 29846670 9606 9606 BIOGRID
PRMT5 ST7 Co-localization 24453002 9606 9606 BIOGRID
PRMT5 GLI1 Biochemical Activity 30675521 9606 9606 BIOGRID
PRMT5 CFLAR Affinity Capture-Western 30736843 9606 9606 BIOGRID
PRMT5 WDR77 Affinity Capture-Western 30392062 9606 9606 BIOGRID
PRMT5 BCL6 Affinity Capture-Western 30082494 9606 9606 BIOGRID
PRMT5 BCL6 Reconstituted Complex 30082494 9606 9606 BIOGRID
PRMT5 HIST1H2AB Biochemical Activity 30082494 9606 9606 BIOGRID
PRMT5 BCL6 Biochemical Activity 30082494 9606 9606 BIOGRID
PRMT5 NCOR2 Co-localization 30082494 9606 9606 BIOGRID
PRMT5 BCL6 Co-localization 30082494 9606 9606 BIOGRID
PRMT5 CDC37 Two-hybrid 32296183 9606 9606 BIOGRID
PRMT5 EPHB6 Two-hybrid 32296183 9606 9606 BIOGRID
PRMT5 C1orf109 Two-hybrid 32296183 9606 9606 BIOGRID
PRMT5 GAS8 Two-hybrid 32296183 9606 9606 BIOGRID
PRMT5 EIF4A3 Two-hybrid 32296183 9606 9606 BIOGRID
PRMT5 WDYHV1 Two-hybrid 32296183 9606 9606 BIOGRID
PRMT5 ZMYND19 Two-hybrid 32296183 9606 9606 BIOGRID
PRMT5 CACNB2 Two-hybrid 32296183 9606 9606 BIOGRID
PRMT5 KANK2 Two-hybrid 32296183 9606 9606 BIOGRID
PRMT5 PLEC Proximity Label-MS 30021884 9606 9606 BIOGRID
PRMT5 RAD1 Affinity Capture-MS 24981860 9606 9606 BIOGRID
PRMT5 SUPT5H Affinity Capture-MS 24981860 9606 9606 BIOGRID
PRMT5 HHV8GK18_gp81 Biochemical Activity 22179613 9606 37296 BIOGRID
PRMT5 Prdm1 Affinity Capture-Western 16699504 9606 10090 BIOGRID
PRMT5 h4-A Biochemical Activity 25713080 9606 8355 BIOGRID
PRMT5 wdr77 Reconstituted Complex 25713080 9606 8355 BIOGRID
 Annotation of PRMT5
 TCGA cancer survival map of PRMT5


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  PRMT5