TcoF overview
| TcoF: | PTTG1 | |
| GeneID: | 494115 | |
| Name: | Securin | |
| Ensembl: | ENSG00000164611 | |
| Species: | Human | |
| Class: | class 3 | |
| Family: | Others | |
| Disease: | 4 | |
| Go term: | 16 | |
| Pathway: | 7 | |
| Hallmark: | 2 | |
| Super Enhancer: |
chr5:159839582-159878224 chr5:159833214-159866741 |
|
| Enhancer: |
chr5:159885120-159886870 chr5:159436200-159437500 chr5:159543710-159545810 chr5:159598500-159599220 chr5:159601180-159603600 chr5:159737750-159738860 chr5:159738980-159739370 chr5:159783640-159785660 chr5:159785970-159787690 chr5:159789740-159791350 chr5:159796180-159797510 chr5:159860020-159861690 chr5:159824290-159826640 chr5:160026880-160029330 chr5:160061610-160063180 chr5:160094630-160096890 chr5:160214280-160214540 chr5:160215900-160217740 chr5:160225290-160227260 chr5:160227530-160228790 chr5:159648050-159648700 chr5:159912460-159914660 chr5:159915580-159917440 chr5:159862460-159863640 chr5:159887220-159888200 chr5:159664050-159665610 chr5:160044420-160044870 chr5:160186940-160189350 chr5:160237090-160239410 chr5:160293280-160294890 chr5:160344220-160345900 chr5:160370630-160371090 chr5:160438260-160439710 chr5:160398570-160400810 chr5:159640830-159640940 chr5:159320390-159321260 chr5:159595850-159597460 chr5:159456630-159458230 chr5:159474360-159475020 chr5:159244340-159245220 chr5:159324150-159325990 chr5:159329550-159330550 chr5:159330760-159332150 chr5:159492550-159493380 chr5:159657160-159659100 chr5:159720120-159722360 chr5:159756910-159757670 chr5:159760640-159761330 chr5:159767920-159770380 chr5:159466670-159467450 chr5:159490370-159491930 chr5:159614460-159616450 chr5:159636390-159638250 chr5:160125480-160127620 chr5:160476760-160478660 chr5:160479160-160480930 chr5:160168730-160171100 chr5:160020210-160022410 chr5:159276150-159277960 chr5:159332160-159333270 chr5:159970620-159972230 chr5:159974460-159976590 chr5:160266000-160267430 chr5:159354710-159356380 chr5:159881770-159884100 chr5:159194380-159196680 chr5:159471140-159473050 chr5:159505180-159507650 chr5:159581500-159583850 chr5:159586500-159588360 chr5:159686780-159689040 chr5:160198250-160200160 chr5:159532320-159534010 chr5:159689050-159689620 chr5:159871530-159873160 chr5:159873490-159875430 chr5:159851510-159852040 chr5:159507780-159509180 |
|
| Promoter: |
chr5:159848862-159855746 |
ChIP-seq based regulatory details of PTTG1
| Sample ID | Experiment target | Biosample type | Biosample term name | GSM ID | Tissue type | Source |
|---|---|---|---|---|---|---|
| TcoF_00_10077 | PTTG1 | cell line | K562 | - | Bone Marrow | ENCODE |
| TcoF_00_40475 | PTTG1 | cell line | K-562 | - | Bone Marrow | ReMap |
| TcoF_00_20696 | PTTG1 | cell line | K562 | - | Bone Marrow | Cistrome |
Downstream target genes of PTTG1
Upstream regulatory details of PTTG1
Protein-protein interaction of PTTG1
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| PTTG1 | DNAJA1 | Reconstituted Complex | 9915854 | 9606 | 9606 | BIOGRID |
| PTTG1 | RPS10 | Reconstituted Complex | 9915854 | 9606 | 9606 | BIOGRID |
| PTTG1 | PTTG1IP | Two-hybrid | 10781616 | 9606 | 9606 | BIOGRID |
| PTTG1 | PTTG1IP | Affinity Capture-Western | 10781616 | 9606 | 9606 | BIOGRID |
| PTTG1 | PTTG1IP | Reconstituted Complex | 10781616 | 9606 | 9606 | BIOGRID |
| PTTG1 | XRCC6 | Two-hybrid | 11238996 | 9606 | 9606 | BIOGRID |
| PTTG1 | XRCC6 | Reconstituted Complex | 11238996 | 9606 | 9606 | BIOGRID |
| PTTG1 | TP53 | Reconstituted Complex | 12355087 | 9606 | 9606 | BIOGRID |
| PTTG1 | TP53 | Affinity Capture-Western | 12355087 | 9606 | 9606 | BIOGRID |
| PTTG1 | BTRC | Affinity Capture-Western | 18460583 | 9606 | 9606 | BIOGRID |
| PTTG1 | NUP98 | Affinity Capture-Western | 16479161 | 9606 | 9606 | BIOGRID |
| PTTG1 | CDC27 | Affinity Capture-Western | 16479161 | 9606 | 9606 | BIOGRID |
| PTTG1 | PTTG1 | Affinity Capture-MS | 20360068 | 9606 | 9606 | BIOGRID |
| PTTG1 | ESPL1 | Affinity Capture-MS | 20360068 | 9606 | 9606 | BIOGRID |
| PTTG1 | DECR1 | Affinity Capture-MS | 20360068 | 9606 | 9606 | BIOGRID |
| PTTG1 | BUB1B | Reconstituted Complex | 19117984 | 9606 | 9606 | BIOGRID |
| PTTG1 | BUB1B | Affinity Capture-Western | 19117984 | 9606 | 9606 | BIOGRID |
| PTTG1 | AURKA | Reconstituted Complex | 19117984 | 9606 | 9606 | BIOGRID |
| PTTG1 | TP53 | Reconstituted Complex | 19117984 | 9606 | 9606 | BIOGRID |
| PTTG1 | CDC20 | Reconstituted Complex | 19117984 | 9606 | 9606 | BIOGRID |
| PTTG1 | ESPL1 | Reconstituted Complex | 19117984 | 9606 | 9606 | BIOGRID |
| PTTG1 | CDC27 | Reconstituted Complex | 16921029 | 9606 | 9606 | BIOGRID |
| PTTG1 | CUL1 | Affinity Capture-Western | 20198633 | 9606 | 9606 | BIOGRID |
| PTTG1 | CUL1 | Reconstituted Complex | 20198633 | 9606 | 9606 | BIOGRID |
| PTTG1 | FZR1 | Affinity Capture-Western | 16479161 | 9606 | 9606 | BIOGRID |
| PTTG1 | ESPL1 | Affinity Capture-MS | 26186194 | 9606 | 9606 | BIOGRID |
| PTTG1 | DECR1 | Affinity Capture-MS | 26186194 | 9606 | 9606 | BIOGRID |
| PTTG1 | DHFR | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | SLC36A1 | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | POLR3K | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | CDK5RAP2 | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | CSNK2B | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | XIAP | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | KPNA6 | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | NUMA1 | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | GPER1 | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | CASP3 | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | TRIM15 | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | B2M | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | WRN | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | FXYD1 | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | KISS1R | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | POLM | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | ZNF358 | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | DCAF17 | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | ZNF142 | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | PCNXL2 | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | NT5M | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | PSMA3 | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | CEP85 | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | ARNTL2 | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | ZBTB48 | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | EZR | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | CREBBP | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | LUC7L3 | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | CDC37L1 | Synthetic Growth Defect | 24104479 | 9606 | 9606 | BIOGRID |
| PTTG1 | HNRNPAB | Affinity Capture-MS | 26496610 | 9606 | 9606 | BIOGRID |
| PTTG1 | HSPG2 | Affinity Capture-MS | 26496610 | 9606 | 9606 | BIOGRID |
| PTTG1 | PMS1 | Affinity Capture-MS | 26496610 | 9606 | 9606 | BIOGRID |
| PTTG1 | ESPL1 | Affinity Capture-MS | 26496610 | 9606 | 9606 | BIOGRID |
| PTTG1 | TTLL5 | Affinity Capture-MS | 26496610 | 9606 | 9606 | BIOGRID |
| PTTG1 | ZC3H3 | Affinity Capture-MS | 26496610 | 9606 | 9606 | BIOGRID |
| PTTG1 | ZCCHC17 | Affinity Capture-MS | 26496610 | 9606 | 9606 | BIOGRID |
| PTTG1 | PPP2R2D | Two-hybrid | 16705156 | 9606 | 9606 | BIOGRID |
| PTTG1 | PPP2R2D | Reconstituted Complex | 16705156 | 9606 | 9606 | BIOGRID |
| PTTG1 | PPP2R2D | Affinity Capture-Western | 16705156 | 9606 | 9606 | BIOGRID |
| PTTG1 | ESPL1 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| PTTG1 | DECR1 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| PTTG1 | ACTBL2 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| PTTG1 | MAPK1 | Affinity Capture-Western | 15845362 | 9606 | 9606 | BIOGRID |
| PTTG1 | PIK3CA | Affinity Capture-Western | 15845362 | 9606 | 9606 | BIOGRID |
| PTTG1 | PIK3R1 | Affinity Capture-Western | 15845362 | 9606 | 9606 | BIOGRID |
| PTTG1 | USP44 | Affinity Capture-Western | 28938551 | 9606 | 9606 | BIOGRID |
| PTTG1 | USP44 | Co-localization | 28938551 | 9606 | 9606 | BIOGRID |
| PTTG1 | RAD51 | Negative Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| PTTG1 | RPL24 | Negative Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| PTTG1 | RPL28 | Negative Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| PTTG1 | RPL32 | Negative Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| PTTG1 | RTF1 | Negative Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| PTTG1 | SKA3 | Positive Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| PTTG1 | SRSF7 | Negative Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| PTTG1 | TRA2B | Positive Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| PTTG1 | UBA2 | Negative Genetic | 30033366 | 9606 | 9606 | BIOGRID |
| PTTG1 | ZNF830 | Negative Genetic | 30033366 | 9606 | 9606 | BIOGRID |
Annotation of PTTG1
TCGA cancer survival map of PTTG1
Expression of PTTG1
Disease information of PTTG1