TcoF overview
TcoF: RBBP8
GeneID: 27316
Name: DNA endonuclease RBBP8
Ensembl: ENSG00000101773
Species: Human
Class: class HC
Family: RBBP
Disease: 11
Go term: 28
Pathway: 16
Hallmark: 2
Super Enhancer:

chr18:20492020-20524692 chr18:20494091-20524633 chr18:20492472-20522548 chr18:20478758-20524760 chr18:20508156-20563321 chr18:20253719-20303685 chr18:20260370-20309725 chr18:20260468-20309609 chr18:20246203-20292573 chr18:20393641-20449603 chr18:20246484-20276256 chr18:20393679-20439082 chr18:20393545-20449740 chr18:20246062-20276566 chr18:20393560-20452679 chr18:20393761-20452502 chr18:20393504-20449766 chr18:20246149-20315789 chr18:20270777-20276525 chr18:20246484-20292211 chr18:20246069-20294458 chr18:20393846-20453562 chr18:20247131-20276303 chr18:20392656-20453811 chr18:20247265-20275723 chr18:20253976-20280570 chr18:20246838-20291811 chr18:20246337-20276899 chr18:20423261-20437555 chr18:20392992-20439194 chr18:20245911-20277105 chr18:20246162-20293313 chr18:20246438-20293834

Enhancer:

chr18:20514120-20516570 chr18:20917800-20918220 chr18:20533780-20534260 chr18:20863460-20865110 chr18:20886560-20888910 chr18:20910190-20912400 chr18:20840440-20842650 chr18:20531790-20533500 chr18:20557590-20559170 chr18:20068550-20069050 chr18:20083630-20086020 chr18:20097030-20098330 chr18:20118280-20119340 chr18:20124270-20124560 chr18:20720810-20722820 chr18:20722910-20724550 chr18:20746410-20747610 chr18:20759380-20761250 chr18:20881920-20884180 chr18:20932730-20934270 chr18:20934380-20936550 chr18:20069240-20070940 chr18:20064900-20067210 chr18:20171130-20171640 chr18:20247370-20248820 chr18:20253840-20255510 chr18:20401540-20403920 chr18:20492740-20495180 chr18:20694270-20696440 chr18:20716570-20719010 chr18:20861460-20863160 chr18:20871070-20872740 chr18:20890840-20893210 chr18:21015350-21017740 chr18:21083680-21084330 chr18:20184080-20185960 chr18:19620430-19620980 chr18:19623900-19626380 chr18:19628620-19630000 chr18:19663720-19665380 chr18:19753930-19754390 chr18:19754430-19755820 chr18:19757080-19757960 chr18:19789930-19790820 chr18:19790930-19791250 chr18:19794380-19795500 chr18:19802790-19804430 chr18:19830420-19831300 chr18:19861800-19863860 chr18:19865170-19866020 chr18:19866480-19867470 chr18:19881580-19882810 chr18:19921990-19922450 chr18:19924290-19926220 chr18:19926290-19927820 chr18:20500940-20502420 chr18:21038590-21039790 chr18:21040330-21041660 chr18:21109680-21109990 chr18:21110100-21110190 chr18:21209920-21210330 chr18:19611320-19613790 chr18:19758000-19760010 chr18:19922530-19924050 chr18:20130370-20132240 chr18:20192510-20194050 chr18:20611230-20613460 chr18:20738780-20739910 chr18:20681660-20682420 chr18:20843380-20844060 chr18:20859210-20860860

Promoter:

chr18:20378224-20606451

 ChIP-seq based regulatory details of RBBP8
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
 Downstream target genes of RBBP8
 Protein-protein interaction of RBBP8
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
RBBP8 RBL1 Two-hybrid 9721205 9606 9606 BIOGRID
RBBP8 LMO4 Two-hybrid 11751867 9606 9606 BIOGRID
RBBP8 HID1 Two-hybrid 16189514 9606 9606 BIOGRID
RBBP8 FXR2 Two-hybrid 16189514 9606 9606 BIOGRID
RBBP8 WDYHV1 Two-hybrid 16189514 9606 9606 BIOGRID
RBBP8 RBL1 Two-hybrid 16189514 9606 9606 BIOGRID
RBBP8 BRCA1 Affinity Capture-Western 10910365 9606 9606 BIOGRID
RBBP8 RBBP8 Affinity Capture-Western 15084581 9606 9606 BIOGRID
RBBP8 RBBP8 Reconstituted Complex 15084581 9606 9606 BIOGRID
RBBP8 IKZF1 Affinity Capture-Western 11959865 9606 9606 BIOGRID
RBBP8 RBL2 Affinity Capture-Western 10449734 9606 9606 BIOGRID
RBBP8 RBL2 Two-hybrid 10449734 9606 9606 BIOGRID
RBBP8 SIAH1 Two-hybrid 14654780 9606 9606 BIOGRID
RBBP8 BRCA1 Reconstituted Complex 10764811 9606 9606 BIOGRID
RBBP8 BRCA1 Two-hybrid 10764811 9606 9606 BIOGRID
RBBP8 CTBP1 Reconstituted Complex 9535825 9606 9606 BIOGRID
RBBP8 CTBP1 Affinity Capture-Western 9535825 9606 9606 BIOGRID
RBBP8 RB1 Two-hybrid 9721205 9606 9606 BIOGRID
RBBP8 RBL2 Two-hybrid 9721205 9606 9606 BIOGRID
RBBP8 RB1 Affinity Capture-Western 16581787 9606 9606 BIOGRID
RBBP8 BARD1 Affinity Capture-Western 16391231 9606 9606 BIOGRID
RBBP8 BARD1 Affinity Capture-Western 20351172 9606 9606 BIOGRID
RBBP8 BRCA1 Affinity Capture-Western 20351172 9606 9606 BIOGRID
RBBP8 ZNF350 Affinity Capture-Western 16843262 9606 9606 BIOGRID
RBBP8 BRCA1 Affinity Capture-Western 16843262 9606 9606 BIOGRID
RBBP8 ATM Affinity Capture-Western 10910365 9606 9606 BIOGRID
RBBP8 BRCA1 Affinity Capture-Western 11689934 9606 9606 BIOGRID
RBBP8 NBN Affinity Capture-Western 18171670 9606 9606 BIOGRID
RBBP8 PCNA Reconstituted Complex 19342888 9606 9606 BIOGRID
RBBP8 PCNA Affinity Capture-Western 19342888 9606 9606 BIOGRID
RBBP8 PCNA Two-hybrid 19342888 9606 9606 BIOGRID
RBBP8 RGS17 Two-hybrid 21988832 9606 9606 BIOGRID
RBBP8 TMEM54 Two-hybrid 21988832 9606 9606 BIOGRID
RBBP8 LMO4 Two-hybrid 25416956 9606 9606 BIOGRID
RBBP8 FZR1 Reconstituted Complex 25349192 9606 9606 BIOGRID
RBBP8 MRE11A Reconstituted Complex 25349192 9606 9606 BIOGRID
RBBP8 FANCD2 Affinity Capture-Western 24556218 9606 9606 BIOGRID
RBBP8 BRCA1 Affinity Capture-Western 25310973 9606 9606 BIOGRID
RBBP8 USP4 Affinity Capture-Western 26455393 9606 9606 BIOGRID
RBBP8 EXD2 Affinity Capture-MS 26807646 9606 9606 BIOGRID
RBBP8 EXO1 Affinity Capture-MS 26807646 9606 9606 BIOGRID
RBBP8 MRE11A Affinity Capture-MS 26807646 9606 9606 BIOGRID
RBBP8 CTBP1 Affinity Capture-MS 26807646 9606 9606 BIOGRID
RBBP8 CTBP2 Affinity Capture-MS 26807646 9606 9606 BIOGRID
RBBP8 EXD2 Affinity Capture-Western 26807646 9606 9606 BIOGRID
RBBP8 BRCA1 Affinity Capture-MS 26387952 9606 9606 BIOGRID
RBBP8 LMO4 Affinity Capture-MS 26387952 9606 9606 BIOGRID
RBBP8 NBN Affinity Capture-MS 26387952 9606 9606 BIOGRID
RBBP8 BRIX1 Affinity Capture-MS 26387952 9606 9606 BIOGRID
RBBP8 DEFA1 Affinity Capture-MS 26387952 9606 9606 BIOGRID
RBBP8 USP4 Affinity Capture-MS 26387952 9606 9606 BIOGRID
RBBP8 SIAH1 Affinity Capture-MS 26387952 9606 9606 BIOGRID
RBBP8 MRE11A Affinity Capture-MS 26387952 9606 9606 BIOGRID
RBBP8 XRCC1 Affinity Capture-MS 26387952 9606 9606 BIOGRID
RBBP8 USP4 Affinity Capture-Western 26387952 9606 9606 BIOGRID
RBBP8 USP4 Reconstituted Complex 26387952 9606 9606 BIOGRID
RBBP8 NBN Affinity Capture-Western 26387952 9606 9606 BIOGRID
RBBP8 FANCD2 Reconstituted Complex 24794434 9606 9606 BIOGRID
RBBP8 FANCD2 Phenotypic Enhancement 24794434 9606 9606 BIOGRID
RBBP8 FANCD2 FRET 24794434 9606 9606 BIOGRID
RBBP8 UBC Far Western 24794434 9606 9606 BIOGRID
RBBP8 FANCD2 Reconstituted Complex 24794430 9606 9606 BIOGRID
RBBP8 FANCD2 Synthetic Lethality 24794430 9606 9606 BIOGRID
RBBP8 FANCD2 Co-localization 24794430 9606 9606 BIOGRID
RBBP8 KLHL15 Affinity Capture-Western 27561354 9606 9606 BIOGRID
RBBP8 CUL3 Affinity Capture-Western 27561354 9606 9606 BIOGRID
RBBP8 KLHL15 Affinity Capture-MS 27561354 9606 9606 BIOGRID
RBBP8 CUL3 Affinity Capture-MS 27561354 9606 9606 BIOGRID
RBBP8 CUL3 Reconstituted Complex 27561354 9606 9606 BIOGRID
RBBP8 KLHL15 Reconstituted Complex 27561354 9606 9606 BIOGRID
RBBP8 MRE11A Reconstituted Complex 27561354 9606 9606 BIOGRID
RBBP8 NBN Reconstituted Complex 27561354 9606 9606 BIOGRID
RBBP8 MRE11A Affinity Capture-Western 27561354 9606 9606 BIOGRID
RBBP8 NBN Affinity Capture-Western 27561354 9606 9606 BIOGRID
RBBP8 CUL3 Protein-peptide 27561354 9606 9606 BIOGRID
RBBP8 KLHL15 Protein-peptide 27561354 9606 9606 BIOGRID
RBBP8 RPL32 Negative Genetic 30033366 9606 9606 BIOGRID
RBBP8 TIMELESS Negative Genetic 30033366 9606 9606 BIOGRID
RBBP8 TIPIN Negative Genetic 30033366 9606 9606 BIOGRID
RBBP8 TRRAP Positive Genetic 30033366 9606 9606 BIOGRID
RBBP8 UBA2 Negative Genetic 30033366 9606 9606 BIOGRID
RBBP8 ZNF598 Positive Genetic 30033366 9606 9606 BIOGRID
RBBP8 RBBP8 Reconstituted Complex 17214969 9606 9606 BIOGRID
RBBP8 RBBP8 Affinity Capture-MS 15084581 9606 9606 BIOGRID
RBBP8 RBBP8 Co-purification 15084581 9606 9606 BIOGRID
RBBP8 BRCA1 Affinity Capture-Western 28132842 9606 9606 BIOGRID
RBBP8 NBN Reconstituted Complex 23468639 9606 9606 BIOGRID
RBBP8 WDHD1 Affinity Capture-MS 27940557 9606 9606 BIOGRID
RBBP8 RAD50 Affinity Capture-MS 27940557 9606 9606 BIOGRID
RBBP8 RPA2 Affinity Capture-MS 27940557 9606 9606 BIOGRID
RBBP8 NBN Affinity Capture-Western 27940557 9606 9606 BIOGRID
RBBP8 RAD50 Affinity Capture-Western 27940557 9606 9606 BIOGRID
RBBP8 WDHD1 Affinity Capture-Western 27940557 9606 9606 BIOGRID
RBBP8 RBBP8 Affinity Capture-Western 22544744 9606 9606 BIOGRID
RBBP8 RBL2 Two-hybrid 32296183 9606 9606 BIOGRID
RBBP8 CTBP1 Affinity Capture-Western 31636387 9606 9606 BIOGRID
RBBP8 BRCA1 Affinity Capture-Western 31636387 9606 9606 BIOGRID
RBBP8 CTBP1 Co-localization 31636387 9606 9606 BIOGRID
RBBP8 BRCA1 Co-localization 31636387 9606 9606 BIOGRID
RBBP8 HDAC2 Affinity Capture-Western 31636387 9606 9606 BIOGRID
RBBP8 CTBP1 Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 SDCBP Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 DHX16 Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 BRCA1 Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 HDAC2 Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 GPKOW Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 PCMT1 Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 HSPA5 Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 EEF1A1 Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 CTBP2 Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 HSP90AB1 Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 PRKDC Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 PDLIM7 Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 XRCC6 Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 ZNF217 Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 SAPCD2 Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 AP3B1 Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 RAD50 Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 PBX3 Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 TAX1BP3 Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 CTNNA2 Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 HIST1H4L Affinity Capture-MS 31636387 9606 9606 BIOGRID
RBBP8 MRE11A Affinity Capture-MS 31636387 9606 9606 BIOGRID
 Annotation of RBBP8
 TCGA cancer survival map of RBBP8


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  RBBP8