TcoF overview
| TcoF: | SYK | |
| GeneID: | 9014 | |
| Name: | Tyrosine-protein kinase SYK | |
| Ensembl: | ENSG00000165025 | |
| Species: | Human | |
| Class: | class HC | |
| Family: | Others | |
| Disease: | 4 | |
| Go term: | 89 | |
| Pathway: | 49 | |
| Hallmark: | 3 | |
| Super Enhancer: |
chr9:93556816-93606221 chr9:93555506-93654908 chr9:93555552-93646372 chr9:93556526-93598039 chr9:93562220-93579446 chr9:93599750-93627967 chr9:93535777-93590933 chr9:93556861-93594329 chr9:93531230-93573344 chr9:93555909-93605917 chr9:93557073-93606009 chr9:93562795-93579426 chr9:93563300-93579150 chr9:93562991-93579155 chr9:93562263-93607123 chr9:93557563-93578893 chr9:93549170-93578934 chr9:93532247-93606227 chr9:93556563-93597258 chr9:93555647-93604939 chr9:93531510-93568543 chr9:93556263-93598268 chr9:93556806-93594541 chr9:93562108-93580792 chr9:93599268-93633646 chr9:93531672-93601338 chr9:93563459-93578972 chr9:93549762-93578941 chr9:93555692-93594682 chr9:93557093-93588353 chr9:93557092-93606838 chr9:93558487-93578479 chr9:93557831-93607184 chr9:93682813-93707848 chr9:93671063-93687395 |
|
| Enhancer: |
chr9:93632230-93634140 chr9:93564290-93565720 chr9:93566010-93567980 chr9:93569060-93570320 chr9:93589860-93591380 chr9:93909100-93911480 chr9:93969340-93971760 chr9:93912400-93914790 chr9:93936350-93938170 chr9:93535880-93537540 chr9:93796740-93798570 chr9:93722830-93724290 chr9:93736700-93737320 chr9:93741350-93741720 chr9:93822510-93824860 chr9:93881930-93882800 chr9:93879600-93881840 chr9:93900820-93901530 chr9:93921960-93922770 chr9:93944000-93945470 chr9:93640590-93641040 chr9:93687620-93688680 chr9:93704670-93705870 chr9:93732360-93732610 chr9:93732890-93733300 chr9:93734600-93735660 chr9:93753480-93755600 chr9:93760750-93761470 chr9:93765030-93766320 chr9:93939240-93941280 chr9:93958830-93961270 chr9:93923650-93924130 chr9:93592440-93592850 chr9:93600080-93600470 chr9:93601120-93601690 chr9:93603210-93604930 chr9:93642710-93643570 chr9:93835390-93835800 chr9:93928390-93929590 |
|
| Promoter: |
chr9:93564069-93660831 |
ChIP-seq based regulatory details of SYK
| Sample ID | Experiment target | Biosample type | Biosample term name | GSM ID | Tissue type | Source |
|---|
Downstream target genes of SYK
Upstream regulatory details of SYK
Protein-protein interaction of SYK
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| SYK | PTK2B | Affinity Capture-Western | 10747947 | 9606 | 9606 | BIOGRID |
| SYK | SH3BP2 | Two-hybrid | 9846481 | 9606 | 9606 | BIOGRID |
| SYK | LYN | Affinity Capture-Western | 7831290 | 9606 | 9606 | BIOGRID |
| SYK | LYN | Reconstituted Complex | 7831290 | 9606 | 9606 | BIOGRID |
| SYK | LAT | Biochemical Activity | 11368773 | 9606 | 9606 | BIOGRID |
| SYK | VAV1 | Two-hybrid | 8986718 | 9606 | 9606 | BIOGRID |
| SYK | RPS6KB1 | Biochemical Activity | 16640565 | 9606 | 9606 | BIOGRID |
| SYK | RPS6KB2 | Biochemical Activity | 16640565 | 9606 | 9606 | BIOGRID |
| SYK | SYK | Co-crystal Structure | 9698567 | 9606 | 9606 | BIOGRID |
| SYK | PRKD1 | Affinity Capture-Western | 8885868 | 9606 | 9606 | BIOGRID |
| SYK | FCER1G | Reconstituted Complex | 8071371 | 9606 | 9606 | BIOGRID |
| SYK | MS4A2 | Reconstituted Complex | 8071371 | 9606 | 9606 | BIOGRID |
| SYK | PAG1 | Reconstituted Complex | 10790433 | 9606 | 9606 | BIOGRID |
| SYK | CD72 | Biochemical Activity | 9590210 | 9606 | 9606 | BIOGRID |
| SYK | ITGB2 | Affinity Capture-Western | 10961871 | 9606 | 9606 | BIOGRID |
| SYK | CTTN | Affinity Capture-Western | 8636079 | 9606 | 9606 | BIOGRID |
| SYK | VAV1 | Biochemical Activity | 11331248 | 9606 | 9606 | BIOGRID |
| SYK | CBL | Affinity Capture-Western | 12435267 | 9606 | 9606 | BIOGRID |
| SYK | FGR | Affinity Capture-Western | 11672534 | 9606 | 9606 | BIOGRID |
| SYK | PXN | Affinity Capture-Western | 9590268 | 9606 | 9606 | BIOGRID |
| SYK | TRAF6 | Affinity Capture-Western | 11418661 | 9606 | 9606 | BIOGRID |
| SYK | TUBA1A | Biochemical Activity | 10862713 | 9606 | 9606 | BIOGRID |
| SYK | CD3E | Reconstituted Complex | 7761456 | 9606 | 9606 | BIOGRID |
| SYK | PTPN6 | Affinity Capture-Western | 10072516 | 9606 | 9606 | BIOGRID |
| SYK | FCGR2A | Affinity Capture-Western | 11141335 | 9606 | 9606 | BIOGRID |
| SYK | HDAC1 | Affinity Capture-Western | 16288017 | 9606 | 9606 | BIOGRID |
| SYK | HDAC3 | Affinity Capture-Western | 16288017 | 9606 | 9606 | BIOGRID |
| SYK | HDAC6 | Affinity Capture-Western | 16288017 | 9606 | 9606 | BIOGRID |
| SYK | HDAC9 | Affinity Capture-Western | 16288017 | 9606 | 9606 | BIOGRID |
| SYK | HDAC1 | Reconstituted Complex | 16288017 | 9606 | 9606 | BIOGRID |
| SYK | HDAC2 | Reconstituted Complex | 16288017 | 9606 | 9606 | BIOGRID |
| SYK | HDAC3 | Reconstituted Complex | 16288017 | 9606 | 9606 | BIOGRID |
| SYK | HDAC4 | Reconstituted Complex | 16288017 | 9606 | 9606 | BIOGRID |
| SYK | HDAC6 | Reconstituted Complex | 16288017 | 9606 | 9606 | BIOGRID |
| SYK | HDAC9 | Reconstituted Complex | 16288017 | 9606 | 9606 | BIOGRID |
| SYK | SP1 | Affinity Capture-Western | 16288017 | 9606 | 9606 | BIOGRID |
| SYK | CALM1 | Biochemical Activity | 3350007 | 9606 | 9606 | BIOGRID |
| SYK | CALM1 | Biochemical Activity | 3472906 | 9606 | 9606 | BIOGRID |
| SYK | TUBG1 | Co-fractionation | 16322234 | 9606 | 9606 | BIOGRID |
| SYK | TUBG1 | Affinity Capture-Western | 16322234 | 9606 | 9606 | BIOGRID |
| SYK | USP25 | Two-hybrid | 19909739 | 9606 | 9606 | BIOGRID |
| SYK | USP25 | Affinity Capture-Western | 19909739 | 9606 | 9606 | BIOGRID |
| SYK | INPP5D | Affinity Capture-MS | 22267732 | 9606 | 9606 | BIOGRID |
| SYK | UBASH3B | Affinity Capture-MS | 22267732 | 9606 | 9606 | BIOGRID |
| SYK | LCP2 | Affinity Capture-MS | 22267732 | 9606 | 9606 | BIOGRID |
| SYK | SEC23B | Affinity Capture-MS | 22267732 | 9606 | 9606 | BIOGRID |
| SYK | NCK1 | Affinity Capture-MS | 22267732 | 9606 | 9606 | BIOGRID |
| SYK | GRAP2 | Affinity Capture-MS | 22267732 | 9606 | 9606 | BIOGRID |
| SYK | GRB2 | Affinity Capture-MS | 22267732 | 9606 | 9606 | BIOGRID |
| SYK | INPP5D | Affinity Capture-Western | 22267732 | 9606 | 9606 | BIOGRID |
| SYK | LCP2 | Affinity Capture-Western | 22267732 | 9606 | 9606 | BIOGRID |
| SYK | UBASH3B | Affinity Capture-Western | 22267732 | 9606 | 9606 | BIOGRID |
| SYK | NCK1 | Affinity Capture-Western | 22267732 | 9606 | 9606 | BIOGRID |
| SYK | GRB2 | Affinity Capture-Western | 22267732 | 9606 | 9606 | BIOGRID |
| SYK | LCK | Two-hybrid | 15536084 | 9606 | 9606 | BIOGRID |
| SYK | PIK3R2 | Two-hybrid | 15536084 | 9606 | 9606 | BIOGRID |
| SYK | FGR | Two-hybrid | 15536084 | 9606 | 9606 | BIOGRID |
| SYK | PIK3R1 | Two-hybrid | 15536084 | 9606 | 9606 | BIOGRID |
| SYK | RPS10 | Two-hybrid | 15536084 | 9606 | 9606 | BIOGRID |
| SYK | PIK3R1 | Reconstituted Complex | 15536084 | 9606 | 9606 | BIOGRID |
| SYK | TYROBP | Reconstituted Complex | 9830044 | 9606 | 9606 | BIOGRID |
| SYK | SLC4A1 | Biochemical Activity | 10605028 | 9606 | 9606 | BIOGRID |
| SYK | PIK3R1 | Affinity Capture-Western | 16921024 | 9606 | 9606 | BIOGRID |
| SYK | TRAIP | Two-hybrid | 19151749 | 9606 | 9606 | BIOGRID |
| SYK | TRAIP | Affinity Capture-Western | 19151749 | 9606 | 9606 | BIOGRID |
| SYK | CBL | Affinity Capture-Western | 16289966 | 9606 | 9606 | BIOGRID |
| SYK | PIK3CG | Affinity Capture-Western | 7721825 | 9606 | 9606 | BIOGRID |
| SYK | VAV2 | Two-hybrid | 11262396 | 9606 | 9606 | BIOGRID |
| SYK | VAV1 | Two-hybrid | 11262396 | 9606 | 9606 | BIOGRID |
| SYK | CBL | Biochemical Activity | 15556646 | 9606 | 9606 | BIOGRID |
| SYK | CBL | Affinity Capture-Western | 7721825 | 9606 | 9606 | BIOGRID |
| SYK | MAPT | Biochemical Activity | 18070606 | 9606 | 9606 | BIOGRID |
| SYK | SYK | Biochemical Activity | 18070606 | 9606 | 9606 | BIOGRID |
| SYK | APP | Reconstituted Complex | 21832049 | 9606 | 9606 | BIOGRID |
| SYK | ERBB4 | Protein-peptide | 16273093 | 9606 | 9606 | BIOGRID |
| SYK | SYK | Biochemical Activity | 16291755 | 9606 | 9606 | BIOGRID |
| SYK | SRC | Affinity Capture-Western | 9389695 | 9606 | 9606 | BIOGRID |
| SYK | TRAF3 | Affinity Capture-Western | 23962979 | 9606 | 9606 | BIOGRID |
| SYK | TRAF6 | Affinity Capture-Western | 23962979 | 9606 | 9606 | BIOGRID |
| SYK | TBK1 | Affinity Capture-Western | 23962979 | 9606 | 9606 | BIOGRID |
| SYK | MAP3K7 | Affinity Capture-Western | 23962979 | 9606 | 9606 | BIOGRID |
| SYK | FCGR3A | Biochemical Activity | 8189062 | 9606 | 9606 | BIOGRID |
| SYK | IL17RA | Affinity Capture-Western | 25202827 | 9606 | 9606 | BIOGRID |
| SYK | TRAF6 | Affinity Capture-Western | 25202827 | 9606 | 9606 | BIOGRID |
| SYK | TRAF3IP2 | Affinity Capture-Western | 25202827 | 9606 | 9606 | BIOGRID |
| SYK | SH2D2A | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| SYK | USP25 | Two-hybrid | 25416956 | 9606 | 9606 | BIOGRID |
| SYK | FAM46A | Two-hybrid | 25814554 | 9606 | 9606 | BIOGRID |
| SYK | HCLS1 | Co-localization | 25241761 | 9606 | 9606 | BIOGRID |
| SYK | CTTN | Co-localization | 25241761 | 9606 | 9606 | BIOGRID |
| SYK | FCGR1A | Co-localization | 25241761 | 9606 | 9606 | BIOGRID |
| SYK | HGS | Biochemical Activity | 22706924 | 9606 | 9606 | BIOGRID |
| SYK | GRM1 | Affinity Capture-Western | 15173175 | 9606 | 9606 | BIOGRID |
| SYK | CBL | Co-localization | 27614019 | 9606 | 9606 | BIOGRID |
| SYK | PTPN6 | Biochemical Activity | 10871605 | 9606 | 9606 | BIOGRID |
| SYK | COASY | Biochemical Activity | 19763791 | 9606 | 9606 | BIOGRID |
| SYK | ABCF1 | Affinity Capture-Western | 30770245 | 9606 | 9606 | BIOGRID |
| SYK | STAT3 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
Annotation of SYK
TCGA cancer survival map of SYK
Expression of SYK
Disease information of SYK