TcoF overview
TcoF: TIRAP
GeneID: 7136
Name: Toll/interleukin-1 receptor domain-containing adapter protein
Ensembl: ENSG00000150455
Species: Human
Class: class HC
Family: Others
Disease: 9
Go term: 42
Pathway: 8
Hallmark: 2
Super Enhancer:

chr11:126195685-126227815 chr11:126201296-126303128 chr11:126197765-126257142 chr11:126194250-126230414 chr11:126192575-126230275 chr11:126202345-126302938 chr11:126202120-126257213 chr11:126201749-126256806 chr11:126202301-126230288

Enhancer:

chr11:126174180-126176460 chr11:126212220-126213200 chr11:126264940-126265920 chr11:126413220-126415410 chr11:126472550-126474020 chr11:126572950-126573350 chr11:126283540-126283850 chr11:126316780-126318900 chr11:126153050-126155440 chr11:126415910-126418150 chr11:126419460-126420580 chr11:126570120-126571820 chr11:126276450-126276830 chr11:126276920-126277140 chr11:126008190-126008880 chr11:126059190-126061330 chr11:126296080-126296410 chr11:126296420-126297980 chr11:125887270-125888220 chr11:126146420-126146960 chr11:126147070-126147320 chr11:126159730-126160350 chr11:126104310-126104880 chr11:126325150-126326240 chr11:125876800-125878030 chr11:126005020-126006090 chr11:126006160-126007980 chr11:126019410-126020600 chr11:126023100-126025270 chr11:126032200-126034040 chr11:126204440-126205640 chr11:126215640-126217170 chr11:126266180-126267200 chr11:126307670-126308880 chr11:126328700-126330990 chr11:126455090-126457560 chr11:126506420-126508910 chr11:126009130-126010680 chr11:126041730-126043510 chr11:126516580-126517670 chr11:125899560-125900540 chr11:125991130-125991760 chr11:125993790-125995060 chr11:125997180-125998950 chr11:126034760-126036730 chr11:126109600-126110680 chr11:125992680-125993460 chr11:125972140-125973400 chr11:125973900-125975560 chr11:126026590-126027160 chr11:126163070-126163560 chr11:126277240-126277460 chr11:126332120-126332880 chr11:125822360-125823780 chr11:125823860-125824220 chr11:125837410-125839190 chr11:125949170-125951660 chr11:125961710-125962590 chr11:125979420-125981710 chr11:126213310-126215240 chr11:126250790-126251330 chr11:126252450-126252980 chr11:126253120-126255070 chr11:126255700-126257660 chr11:126257780-126258150 chr11:126299690-126300830 chr11:126305190-126306700 chr11:126205840-126208180 chr11:126371540-126371890 chr11:126371940-126372860 chr11:126241480-126241790 chr11:126292410-126293390 chr11:126294920-126295530 chr11:125941180-125943650 chr11:126327080-126327880 chr11:126366340-126367960 chr11:126433560-126435600 chr11:126127080-126128610 chr11:125820460-125822170 chr11:125804770-125806440 chr11:125923040-125923430 chr11:126073550-126074120 chr11:126295620-126296010 chr11:126459450-126460130 chr11:126709120-126710990 chr11:126711720-126712460 chr11:126739920-126740430

Promoter:

chr11:126152960-126168740

 ChIP-seq based regulatory details of TIRAP
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
 Downstream target genes of TIRAP
 Protein-protein interaction of TIRAP
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
TIRAP TLR4 Affinity Capture-Western 11526399 9606 9606 BIOGRID
TIRAP TLR4 Reconstituted Complex 11526399 9606 9606 BIOGRID
TIRAP MYD88 Phenotypic Suppression 11544529 9606 9606 BIOGRID
TIRAP TIRAP Two-hybrid 11544529 9606 9606 BIOGRID
TIRAP MYD88 Two-hybrid 11544529 9606 9606 BIOGRID
TIRAP IRAK2 Phenotypic Suppression 11544529 9606 9606 BIOGRID
TIRAP TRAF6 Phenotypic Suppression 11544529 9606 9606 BIOGRID
TIRAP MAP3K7 Phenotypic Suppression 11544529 9606 9606 BIOGRID
TIRAP IRAK2 Affinity Capture-Western 11544529 9606 9606 BIOGRID
TIRAP TLR4 Affinity Capture-Western 11544529 9606 9606 BIOGRID
TIRAP MYD88 PCA 17258210 9606 9606 BIOGRID
TIRAP MYD88 PCA 18221795 9606 9606 BIOGRID
TIRAP MYD88 PCA 20048342 9606 9606 BIOGRID
TIRAP MYD88 Affinity Capture-Western 20048342 9606 9606 BIOGRID
TIRAP IRAK1 Affinity Capture-MS 21903422 9606 9606 BIOGRID
TIRAP IRAK2 Affinity Capture-MS 21903422 9606 9606 BIOGRID
TIRAP IRAK4 Affinity Capture-MS 21903422 9606 9606 BIOGRID
TIRAP TLR4 Affinity Capture-MS 21903422 9606 9606 BIOGRID
TIRAP NF1 Affinity Capture-MS 21903422 9606 9606 BIOGRID
TIRAP ARAF Affinity Capture-MS 21903422 9606 9606 BIOGRID
TIRAP CCDC47 Affinity Capture-MS 21903422 9606 9606 BIOGRID
TIRAP JAK1 Affinity Capture-MS 21903422 9606 9606 BIOGRID
TIRAP PDS5A Affinity Capture-MS 21903422 9606 9606 BIOGRID
TIRAP LTN1 Affinity Capture-MS 21903422 9606 9606 BIOGRID
TIRAP RPTOR Affinity Capture-MS 21903422 9606 9606 BIOGRID
TIRAP SAMHD1 Affinity Capture-MS 21903422 9606 9606 BIOGRID
TIRAP SNRNP200 Affinity Capture-MS 21903422 9606 9606 BIOGRID
TIRAP STAT3 Affinity Capture-MS 21903422 9606 9606 BIOGRID
TIRAP TAB2 Affinity Capture-MS 21903422 9606 9606 BIOGRID
TIRAP UBR1 Affinity Capture-MS 21903422 9606 9606 BIOGRID
TIRAP UBR2 Affinity Capture-MS 21903422 9606 9606 BIOGRID
TIRAP ARAF Reconstituted Complex 21903422 9606 9606 BIOGRID
TIRAP CCDC47 Reconstituted Complex 21903422 9606 9606 BIOGRID
TIRAP IRAK1 Reconstituted Complex 21903422 9606 9606 BIOGRID
TIRAP IRAK4 Reconstituted Complex 21903422 9606 9606 BIOGRID
TIRAP LTN1 Reconstituted Complex 21903422 9606 9606 BIOGRID
TIRAP SAMHD1 Reconstituted Complex 21903422 9606 9606 BIOGRID
TIRAP BTK Affinity Capture-Western 12724322 9606 9606 BIOGRID
TIRAP TICAM2 Affinity Capture-Western 12721283 9606 9606 BIOGRID
TIRAP TRAF6 Affinity Capture-Western 19592497 9606 9606 BIOGRID
TIRAP TRAF6 Affinity Capture-Western 24084649 9606 9606 BIOGRID
TIRAP MAP3K7 Affinity Capture-Western 24084649 9606 9606 BIOGRID
TIRAP TAB1 Affinity Capture-Western 24084649 9606 9606 BIOGRID
TIRAP TNFSF9 Affinity Capture-Western 24084649 9606 9606 BIOGRID
TIRAP CAMK2D Affinity Capture-MS 26186194 9606 9606 BIOGRID
TIRAP CAMK2G Affinity Capture-MS 26186194 9606 9606 BIOGRID
TIRAP DHPS Affinity Capture-MS 26186194 9606 9606 BIOGRID
TIRAP NTMT1 Affinity Capture-MS 26186194 9606 9606 BIOGRID
TIRAP BTBD9 Affinity Capture-MS 26186194 9606 9606 BIOGRID
TIRAP KLHL24 Affinity Capture-MS 26186194 9606 9606 BIOGRID
TIRAP TEP1 Affinity Capture-MS 26186194 9606 9606 BIOGRID
TIRAP NTMT1 Affinity Capture-MS 28514442 9606 9606 BIOGRID
TIRAP DHPS Affinity Capture-MS 28514442 9606 9606 BIOGRID
TIRAP TEP1 Affinity Capture-MS 28514442 9606 9606 BIOGRID
TIRAP CAMK2G Affinity Capture-MS 28514442 9606 9606 BIOGRID
TIRAP CAMK2D Affinity Capture-MS 28514442 9606 9606 BIOGRID
 Annotation of TIRAP
 TCGA cancer survival map of TIRAP


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  TIRAP