TcoF overview
| TcoF: | TLE3 | |
| GeneID: | 117854 | |
| Name: | Transducin-like enhancer protein 3 | |
| Ensembl: | ENSG00000140332 | |
| Species: | Human | |
| Class: | class 3 | |
| Family: | Transducin | |
| Disease: | 7 | |
| Go term: | 13 | |
| Pathway: | 19 | |
| Hallmark: | -- | |
| Super Enhancer: |
chr15:70439646-70510952 chr15:70426865-70519603 chr15:70434754-70493849 chr15:70432301-70516240 chr15:70383249-70404721 chr15:70387457-70415814 chr15:70380788-70404684 chr15:70384262-70394019 chr15:70383504-70404428 chr15:70386978-70393967 chr15:70387403-70393944 chr15:70380635-70414821 chr15:70381243-70421357 chr15:70384055-70459384 chr15:70379264-70406681 chr15:70380660-70414681 chr15:70386804-70414455 chr15:70380398-70414858 chr15:70380814-70458728 chr15:70383514-70391907 chr15:70383319-70404681 chr15:70387338-70393323 chr15:70374852-70394465 chr15:70384157-70393838 chr15:70385233-70393778 chr15:70383447-70404288 chr15:70383320-70404301 chr15:70339337-70365247 chr15:70387227-70413851 chr15:70387484-70404845 chr15:70386991-70405096 chr15:70387274-70404808 chr15:70385316-70407794 chr15:70383305-70464697 chr15:70387305-70393838 chr15:70383253-70404978 chr15:70378235-70393480 chr15:70384397-70404421 chr15:70383192-70407301 chr15:70381020-70520450 chr15:70369900-70404729 chr15:70452660-70497708 chr15:70370382-70420874 chr15:70370759-70393918 chr15:70486929-70493431 chr15:70609738-70636749 chr15:70531714-70575336 chr15:70532577-70560179 chr15:70526361-70563934 chr15:70510954-70565889 chr15:70615058-70680840 chr15:70539632-70602007 chr15:70483112-70493458 chr15:70483291-70493230 chr15:70443782-70494105 chr15:70615041-70650504 chr15:70536252-70691200 chr15:70445695-70493405 chr15:70539791-70587286 chr15:70614767-70651172 chr15:70610631-70682139 chr15:70615261-70682854 chr15:70533866-70564777 chr15:70551174-70587620 chr15:70604622-70629684 chr15:70629023-70680743 chr15:70540100-70587416 chr15:70533426-70566390 chr15:70533831-70566181 chr15:70557172-70569773 |
|
| Enhancer: |
chr15:70348710-70349790 chr15:70386910-70387060 chr15:70347020-70347380 chr15:70347640-70348630 chr15:70364590-70365560 chr15:70343810-70344710 chr15:70765750-70766200 chr15:70785950-70788200 chr15:70797670-70798940 chr15:70213680-70214920 chr15:70279550-70281590 chr15:70281730-70282140 chr15:70376810-70379000 chr15:70286010-70288440 chr15:70344860-70345560 chr15:70345710-70346770 chr15:70145530-70146570 chr15:70381190-70382660 chr15:71119920-71120580 chr15:71122050-71122650 chr15:71125460-71127460 chr15:71151680-71152240 chr15:71193360-71195800 chr15:71247320-71247960 chr15:71339640-71341740 chr15:71343380-71345170 chr15:71347780-71348490 chr15:71358950-71359990 chr15:71374040-71376530 chr15:71388660-71389880 chr15:71154950-71157300 chr15:71171230-71172270 chr15:70102140-70103620 chr15:70314980-70317230 chr15:69745360-69745980 chr15:69747880-69750060 chr15:69883120-69885180 chr15:69885300-69885670 chr15:69886030-69888440 chr15:69916150-69916860 chr15:69918620-69919700 chr15:69921670-69922690 chr15:70050440-70052020 chr15:70104760-70106100 chr15:70265420-70265940 chr15:70289040-70291510 chr15:70356800-70358350 chr15:70701500-70702610 chr15:70702620-70703520 chr15:70705000-70705820 chr15:70721820-70723080 chr15:70770100-70772000 chr15:70789980-70790970 chr15:70809080-70810980 chr15:70831270-70831460 chr15:70867200-70868580 chr15:70923310-70924180 chr15:70925360-70926290 chr15:70935200-70937420 chr15:70945600-70946750 chr15:70989550-70991760 chr15:71005260-71007760 chr15:71008270-71008880 chr15:71032780-71034860 chr15:70909160-70910760 chr15:70342540-70343720 chr15:70730830-70731590 chr15:70640320-70642760 chr15:69823860-69824680 chr15:69829480-69830180 chr15:69940450-69942140 chr15:70085690-70088030 chr15:70112820-70114660 chr15:70149260-70151340 chr15:70153200-70154760 chr15:70462200-70464660 chr15:70961800-70963370 chr15:71034940-71037410 chr15:70010700-70012350 chr15:70018190-70019240 chr15:70019280-70020280 chr15:70739110-70741530 chr15:70772070-70773760 chr15:70964200-70964300 chr15:70964340-70966430 chr15:70678040-70680300 chr15:70723660-70724980 chr15:70726400-70728780 chr15:70751560-70753790 chr15:70754300-70756650 chr15:70919640-70921660 chr15:71040310-71041690 chr15:69782760-69783990 chr15:70043290-70044560 chr15:70046820-70049300 chr15:70049590-70050030 chr15:70100080-70101980 chr15:70142150-70143300 chr15:70199580-70201650 chr15:70317300-70318610 chr15:70418760-70421060 chr15:70671560-70673420 chr15:70729360-70729710 chr15:70731640-70732410 chr15:70139900-70141690 chr15:70417580-70418650 |
|
| Promoter: |
chr15:70340129-70390515 |
ChIP-seq based regulatory details of TLE3
| Sample ID | Experiment target | Biosample type | Biosample term name | GSM ID | Tissue type | Source |
|---|---|---|---|---|---|---|
| TcoF_00_20893 | TLE3 | cell line | MCF-7 | GSM1019137 | Breast | Cistrome |
| TcoF_00_20814 | TLE3 | cell line | LNCaP | GSM2480822 | Prostate | Cistrome |
| TcoF_00_41084 | TLE3 | cell line | LNCaP | GSM2480822 | Prostate | ReMap |
| TcoF_00_20813 | TLE3 | cell line | LNCaP | GSM2480823 | Prostate | Cistrome |
| TcoF_00_41085 | TLE3 | cell line | LNCaP | GSM2480823 | Prostate | ReMap |
| TcoF_00_20816 | TLE3 | cell line | LNCaP | GSM2480824 | Prostate | Cistrome |
| TcoF_00_20815 | TLE3 | cell line | LNCaP | GSM2480825 | Prostate | Cistrome |
| TcoF_00_30153 | TLE3 | cell line | LNCAP | GSM3508103 | Prostate | ChIP-Atlas |
| TcoF_00_30044 | TLE3 | cell line | C4-2 | GSM3508104 | Prostate | ChIP-Atlas |
| TcoF_00_30151 | TLE3 | cell line | LAPC-4 | GSM3508105 | Prostate | ChIP-Atlas |
| TcoF_00_30017 | TLE3 | cell line | 22Rv1 | GSM3508116 | Prostate | ChIP-Atlas |
| TcoF_00_30018 | TLE3 | cell line | 22Rv1 | GSM3508117 | Prostate | ChIP-Atlas |
| TcoF_00_30019 | TLE3 | cell line | 22Rv1 | GSM3508118 | Prostate | ChIP-Atlas |
| TcoF_00_30020 | TLE3 | cell line | 22Rv1 | GSM3508119 | Prostate | ChIP-Atlas |
Downstream target genes of TLE3
Upstream regulatory details of TLE3
Protein-protein interaction of TLE3
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| TLE3 | APP | Reconstituted Complex | 21832049 | 9606 | 9606 | BIOGRID |
| TLE3 | ARCN1 | Co-fractionation | 22863883 | 9606 | 9606 | BIOGRID |
| TLE3 | COPB1 | Co-fractionation | 22863883 | 9606 | 9606 | BIOGRID |
| TLE3 | COPG1 | Co-fractionation | 22863883 | 9606 | 9606 | BIOGRID |
| TLE3 | COPZ1 | Co-fractionation | 22863883 | 9606 | 9606 | BIOGRID |
| TLE3 | KLC1 | Co-fractionation | 22863883 | 9606 | 9606 | BIOGRID |
| TLE3 | AHCY | Co-fractionation | 26344197 | 9606 | 9606 | BIOGRID |
| TLE3 | PPA1 | Co-fractionation | 26344197 | 9606 | 9606 | BIOGRID |
| TLE3 | RPE | Co-fractionation | 26344197 | 9606 | 9606 | BIOGRID |
| TLE3 | STAM | Co-fractionation | 26344197 | 9606 | 9606 | BIOGRID |
| TLE3 | TLE3 | Reconstituted Complex | 22304967 | 9606 | 9606 | BIOGRID |
| TLE3 | TLE4 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| TLE3 | MYH2 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| TLE3 | MYH1 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| TLE3 | MYH4 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| TLE3 | MYH3 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| TLE3 | MYH7 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| TLE3 | ACTA1 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| TLE3 | MYH8 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| TLE3 | TTN | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| TLE3 | TLE1 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| TLE3 | TLE2 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| TLE3 | MYL1 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| TLE3 | ATP2A1 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| TLE3 | LDHC | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| TLE3 | COL1A1 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| TLE3 | EEF1A2 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| TLE3 | PYGM | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| TLE3 | RNF6 | Affinity Capture-Western | 29374067 | 9606 | 9606 | BIOGRID |
| TLE3 | CTNNB1 | Affinity Capture-Western | 29374067 | 9606 | 9606 | BIOGRID |
| TLE3 | SIX2 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| TLE3 | KRTAP15-1 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| TLE3 | NR3C1 | Phenotypic Suppression | 31855178 | 9606 | 9606 | BIOGRID |
| TLE3 | TLE2 | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| TLE3 | CIAO1 | Affinity Capture-MS | 24981860 | 9606 | 9606 | BIOGRID |
| TLE3 | Foxg1 | Reconstituted Complex | 11238932 | 9606 | 10090 | BIOGRID |
Annotation of TLE3
TCGA cancer survival map of TLE3
Expression of TLE3
Disease information of TLE3