TcoF overview
| TcoF: | UHRF1 | |
| GeneID: | 23326 | |
| Name: | E3 ubiquitin-protein ligase UHRF1 | |
| Ensembl: | ENSG00000276043 | |
| Species: | Human | |
| Class: | class HC | |
| Family: | Others | |
| Disease: | 1 | |
| Go term: | 31 | |
| Pathway: | 1 | |
| Hallmark: | 3 | |
| Super Enhancer: |
chr19:4909058-4928038 chr19:4908792-4930029 chr19:4908652-4916768 chr19:4909281-4929081 chr19:4908932-4931702 chr19:4908836-4933366 chr19:4894650-4934936 chr19:4894619-4934225 |
|
| Enhancer: |
chr19:4872780-4874500 chr19:5092570-5094080 chr19:5108440-5110630 chr19:5095020-5096180 chr19:4860420-4861340 chr19:4692180-4694670 chr19:4865320-4867620 chr19:4985340-4985940 chr19:4987020-4989390 chr19:5172690-5174090 chr19:4836760-4838340 chr19:4852310-4852910 chr19:4668650-4670170 chr19:4814020-4815940 chr19:4861420-4863000 chr19:4863320-4865050 chr19:5142480-5143970 chr19:4534110-4535170 chr19:4606220-4608320 chr19:4741980-4744140 chr19:5225860-5226450 chr19:5237030-5238920 chr19:5250080-5252300 chr19:5270710-5271570 chr19:4363470-4363710 chr19:4247170-4249220 chr19:4266540-4267620 chr19:4557030-4557170 chr19:4557240-4558030 chr19:4744460-4745480 chr19:4516690-4517560 chr19:4695570-4697560 chr19:4706810-4707720 chr19:4707880-4708970 chr19:4709260-4711500 chr19:4711810-4714090 chr19:4972160-4973280 chr19:5018140-5019250 chr19:5034070-5036510 chr19:5090640-5092530 chr19:5112150-5114040 chr19:5186060-5187000 chr19:4504960-4507450 chr19:5045040-5047480 chr19:4504800-4504870 chr19:4844810-4846920 chr19:4229620-4231180 chr19:4328810-4329950 chr19:4337210-4338520 chr19:4343990-4345210 chr19:4388120-4389850 chr19:4454090-4455210 chr19:4609740-4610780 chr19:4640170-4642520 chr19:4694840-4695380 chr19:4697660-4698070 chr19:4704320-4705860 chr19:4714350-4716520 chr19:4877420-4879720 chr19:4889090-4890220 chr19:4894720-4896680 chr19:5289380-5290310 chr19:5290490-5291040 chr19:5297600-5299500 chr19:5321360-5322780 chr19:4390310-4392400 chr19:5307920-5310380 chr19:4799930-4801690 chr19:5828340-5830640 chr19:4592470-4594010 chr19:4393700-4395780 chr19:4745550-4745920 chr19:5016890-5017630 chr19:5057720-5060120 chr19:5060380-5061410 chr19:5071590-5072360 chr19:5132020-5133890 chr19:5176160-5178250 chr19:4327220-4327310 chr19:4327380-4328670 chr19:4366990-4368850 chr19:4491830-4493690 chr19:4555580-4555990 chr19:4556100-4556960 chr19:4649310-4650560 chr19:4689740-4690880 chr19:5286760-5289190 chr19:4933440-4933910 chr19:5076620-5077120 chr19:4327000-4327120 chr19:4991000-4993010 |
|
| Promoter: |
chr19:4903092-4962165 |
ChIP-seq based regulatory details of UHRF1
| Sample ID | Experiment target | Biosample type | Biosample term name | GSM ID | Tissue type | Source |
|---|
Downstream target genes of UHRF1
Upstream regulatory details of UHRF1
Protein-protein interaction of UHRF1
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| UHRF1 | DNMT1 | Two-hybrid | 17934516 | 9606 | 9606 | BIOGRID |
| UHRF1 | DNMT1 | Reconstituted Complex | 17934516 | 9606 | 9606 | BIOGRID |
| UHRF1 | DNMT1 | Affinity Capture-Western | 17934516 | 9606 | 9606 | BIOGRID |
| UHRF1 | HDAC1 | Affinity Capture-Western | 17934516 | 9606 | 9606 | BIOGRID |
| UHRF1 | DNMT3A | Affinity Capture-Western | 19798101 | 9606 | 9606 | BIOGRID |
| UHRF1 | DNMT3B | Affinity Capture-Western | 19798101 | 9606 | 9606 | BIOGRID |
| UHRF1 | KAT5 | Affinity Capture-Western | 19800870 | 9606 | 9606 | BIOGRID |
| UHRF1 | DNMT1 | Affinity Capture-Western | 19800870 | 9606 | 9606 | BIOGRID |
| UHRF1 | HDAC1 | Affinity Capture-Western | 19800870 | 9606 | 9606 | BIOGRID |
| UHRF1 | EHMT2 | Affinity Capture-Western | 19056828 | 9606 | 9606 | BIOGRID |
| UHRF1 | HDAC1 | Affinity Capture-Western | 15361834 | 9606 | 9606 | BIOGRID |
| UHRF1 | UHRF1BP1 | Affinity Capture-MS | 15361834 | 9606 | 9606 | BIOGRID |
| UHRF1 | UHRF1BP1 | Affinity Capture-Western | 15361834 | 9606 | 9606 | BIOGRID |
| UHRF1 | USP7 | Affinity Capture-Western | 21745816 | 9606 | 9606 | BIOGRID |
| UHRF1 | DNMT1 | Affinity Capture-Western | 21745816 | 9606 | 9606 | BIOGRID |
| UHRF1 | USP7 | Reconstituted Complex | 21745816 | 9606 | 9606 | BIOGRID |
| UHRF1 | DNMT1 | Reconstituted Complex | 21745816 | 9606 | 9606 | BIOGRID |
| UHRF1 | USP7 | Affinity Capture-Western | 21268065 | 9606 | 9606 | BIOGRID |
| UHRF1 | DNMT1 | Biochemical Activity | 21268065 | 9606 | 9606 | BIOGRID |
| UHRF1 | DNMT1 | Affinity Capture-Western | 21045206 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST1H3A | Protein-peptide | 22064703 | 9606 | 9606 | BIOGRID |
| UHRF1 | TRIM28 | Affinity Capture-Western | 22055183 | 9606 | 9606 | BIOGRID |
| UHRF1 | USP7 | Affinity Capture-MS | 22411829 | 9606 | 9606 | BIOGRID |
| UHRF1 | USP11 | Affinity Capture-MS | 22411829 | 9606 | 9606 | BIOGRID |
| UHRF1 | UHRF2 | Affinity Capture-MS | 22411829 | 9606 | 9606 | BIOGRID |
| UHRF1 | HDAC1 | Affinity Capture-MS | 22411829 | 9606 | 9606 | BIOGRID |
| UHRF1 | USP7 | Affinity Capture-Western | 22411829 | 9606 | 9606 | BIOGRID |
| UHRF1 | USP11 | Affinity Capture-Western | 22411829 | 9606 | 9606 | BIOGRID |
| UHRF1 | SUZ12 | Affinity Capture-Western | 22330138 | 9606 | 9606 | BIOGRID |
| UHRF1 | EZH2 | Affinity Capture-Western | 22330138 | 9606 | 9606 | BIOGRID |
| UHRF1 | SUV39H1 | Affinity Capture-Western | 22330138 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST2H3C | Co-crystal Structure | 22837395 | 9606 | 9606 | BIOGRID |
| UHRF1 | PML | Affinity Capture-Western | 22945642 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST2H3A | Co-crystal Structure | 21489993 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST2H3C | Co-crystal Structure | 21489993 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST2H3D | Co-crystal Structure | 21489993 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST2H3A | Protein-peptide | 21489993 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST2H3C | Protein-peptide | 21489993 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST2H3D | Protein-peptide | 21489993 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST3H3 | Reconstituted Complex | 22100450 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST3H3 | Co-crystal Structure | 22100450 | 9606 | 9606 | BIOGRID |
| UHRF1 | RB1 | Affinity Capture-Western | 16007129 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST2H3C | Protein-peptide | 23022729 | 9606 | 9606 | BIOGRID |
| UHRF1 | DNMT1 | Affinity Capture-Western | 20613874 | 9606 | 9606 | BIOGRID |
| UHRF1 | ZPR1 | Co-fractionation | 22939629 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST3H3 | Reconstituted Complex | 23161542 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST3H3 | Co-crystal Structure | 23161542 | 9606 | 9606 | BIOGRID |
| UHRF1 | UHRF1 | Biochemical Activity | 23161542 | 9606 | 9606 | BIOGRID |
| UHRF1 | USP7 | Affinity Capture-Western | 23297342 | 9606 | 9606 | BIOGRID |
| UHRF1 | BTRC | Affinity Capture-Western | 23297342 | 9606 | 9606 | BIOGRID |
| UHRF1 | CUL1 | Affinity Capture-Western | 23297342 | 9606 | 9606 | BIOGRID |
| UHRF1 | MPG | Affinity Capture-Western | 23537643 | 9606 | 9606 | BIOGRID |
| UHRF1 | KAT5 | Affinity Capture-Western | 23677994 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST3H3 | Protein-peptide | 23752590 | 9606 | 9606 | BIOGRID |
| UHRF1 | USP7 | Affinity Capture-Western | 24013172 | 9606 | 9606 | BIOGRID |
| UHRF1 | DNMT1 | Reconstituted Complex | 24368767 | 9606 | 9606 | BIOGRID |
| UHRF1 | DNMT1 | Affinity Capture-Western | 24782312 | 9606 | 9606 | BIOGRID |
| UHRF1 | DNMT1 | Biochemical Activity | 24782312 | 9606 | 9606 | BIOGRID |
| UHRF1 | UHRF1 | Biochemical Activity | 24782312 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST1H3A | Biochemical Activity | 17967883 | 9606 | 9606 | BIOGRID |
| UHRF1 | UHRF1 | Biochemical Activity | 17967883 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST3H3 | Protein-peptide | 24813945 | 9606 | 9606 | BIOGRID |
| UHRF1 | MBD4 | Affinity Capture-Western | 25358258 | 9606 | 9606 | BIOGRID |
| UHRF1 | MBD4 | Reconstituted Complex | 25358258 | 9606 | 9606 | BIOGRID |
| UHRF1 | MUS81 | Affinity Capture-Western | 25818288 | 9606 | 9606 | BIOGRID |
| UHRF1 | ERCC1 | Affinity Capture-Western | 25818288 | 9606 | 9606 | BIOGRID |
| UHRF1 | ERCC4 | Affinity Capture-Western | 25818288 | 9606 | 9606 | BIOGRID |
| UHRF1 | EME1 | Affinity Capture-Western | 25818288 | 9606 | 9606 | BIOGRID |
| UHRF1 | ERCC1 | Reconstituted Complex | 25818288 | 9606 | 9606 | BIOGRID |
| UHRF1 | MUS81 | Reconstituted Complex | 25818288 | 9606 | 9606 | BIOGRID |
| UHRF1 | TOP2A | Reconstituted Complex | 25451918 | 9606 | 9606 | BIOGRID |
| UHRF1 | TOP2A | Affinity Capture-Western | 25451918 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST3H3 | Protein-peptide | 26065575 | 9606 | 9606 | BIOGRID |
| UHRF1 | AOC4P | Affinity Capture-RNA | 26768845 | 9606 | 9606 | BIOGRID |
| UHRF1 | BTRC | Affinity Capture-Western | 26768845 | 9606 | 9606 | BIOGRID |
| UHRF1 | FBXW11 | Affinity Capture-Western | 26768845 | 9606 | 9606 | BIOGRID |
| UHRF1 | USP7 | Affinity Capture-Western | 26299963 | 9606 | 9606 | BIOGRID |
| UHRF1 | UHRF1 | Biochemical Activity | 26299963 | 9606 | 9606 | BIOGRID |
| UHRF1 | UBE2D3 | Reconstituted Complex | 26299963 | 9606 | 9606 | BIOGRID |
| UHRF1 | USP7 | Reconstituted Complex | 26046769 | 9606 | 9606 | BIOGRID |
| UHRF1 | TP53 | Affinity Capture-Western | 26102039 | 9606 | 9606 | BIOGRID |
| UHRF1 | TP53 | Reconstituted Complex | 26102039 | 9606 | 9606 | BIOGRID |
| UHRF1 | TP53 | Biochemical Activity | 26102039 | 9606 | 9606 | BIOGRID |
| UHRF1 | PRMT5 | Affinity Capture-Western | 26597461 | 9606 | 9606 | BIOGRID |
| UHRF1 | HSPA1A | Affinity Capture-Western | 27489107 | 9606 | 9606 | BIOGRID |
| UHRF1 | HSP90AA1 | Affinity Capture-Western | 27489107 | 9606 | 9606 | BIOGRID |
| UHRF1 | LIG1 | Affinity Capture-MS | 28803780 | 9606 | 9606 | BIOGRID |
| UHRF1 | USP7 | Affinity Capture-MS | 28803780 | 9606 | 9606 | BIOGRID |
| UHRF1 | XRCC5 | Affinity Capture-MS | 28803780 | 9606 | 9606 | BIOGRID |
| UHRF1 | MCM3 | Affinity Capture-MS | 28803780 | 9606 | 9606 | BIOGRID |
| UHRF1 | MSH2 | Affinity Capture-MS | 28803780 | 9606 | 9606 | BIOGRID |
| UHRF1 | SMARCA5 | Affinity Capture-MS | 28803780 | 9606 | 9606 | BIOGRID |
| UHRF1 | MSH6 | Affinity Capture-MS | 28803780 | 9606 | 9606 | BIOGRID |
| UHRF1 | PRPF8 | Affinity Capture-MS | 28803780 | 9606 | 9606 | BIOGRID |
| UHRF1 | RSF1 | Affinity Capture-MS | 28803780 | 9606 | 9606 | BIOGRID |
| UHRF1 | CBX3 | Affinity Capture-MS | 28803780 | 9606 | 9606 | BIOGRID |
| UHRF1 | H2AFY | Affinity Capture-MS | 28803780 | 9606 | 9606 | BIOGRID |
| UHRF1 | DNMT1 | Affinity Capture-Western | 28803780 | 9606 | 9606 | BIOGRID |
| UHRF1 | LIG1 | Affinity Capture-Western | 28803780 | 9606 | 9606 | BIOGRID |
| UHRF1 | LIG1 | Co-localization | 28803780 | 9606 | 9606 | BIOGRID |
| UHRF1 | LIG1 | Reconstituted Complex | 28803780 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST3H3 | Biochemical Activity | 27595565 | 9606 | 9606 | BIOGRID |
| UHRF1 | UBE2D3 | Reconstituted Complex | 27595565 | 9606 | 9606 | BIOGRID |
| UHRF1 | UHRF1 | Biochemical Activity | 27595565 | 9606 | 9606 | BIOGRID |
| UHRF1 | KAT5 | Affinity Capture-Western | 29268763 | 9606 | 9606 | BIOGRID |
| UHRF1 | DNMT1 | Affinity Capture-Western | 29268763 | 9606 | 9606 | BIOGRID |
| UHRF1 | UHRF1 | Biochemical Activity | 30104358 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST3H3 | Biochemical Activity | 30104358 | 9606 | 9606 | BIOGRID |
| UHRF1 | UBE2D1 | Reconstituted Complex | 30104358 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST3H3 | Reconstituted Complex | 29395786 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST1H3A | Biochemical Activity | 29506131 | 9606 | 9606 | BIOGRID |
| UHRF1 | UHRF1 | Biochemical Activity | 29506131 | 9606 | 9606 | BIOGRID |
| UHRF1 | UBE2D1 | Reconstituted Complex | 29506131 | 9606 | 9606 | BIOGRID |
| UHRF1 | WRAP53 | Affinity Capture-Western | 29516630 | 9606 | 9606 | BIOGRID |
| UHRF1 | UHRF2 | Affinity Capture-Western | 30335751 | 9606 | 9606 | BIOGRID |
| UHRF1 | FANCD2 | Affinity Capture-Western | 30335751 | 9606 | 9606 | BIOGRID |
| UHRF1 | FANCD2 | Reconstituted Complex | 30335751 | 9606 | 9606 | BIOGRID |
| UHRF1 | SETD7 | Reconstituted Complex | 30357346 | 9606 | 9606 | BIOGRID |
| UHRF1 | SETD7 | Affinity Capture-Western | 30357346 | 9606 | 9606 | BIOGRID |
| UHRF1 | PCNA | Biochemical Activity | 30357346 | 9606 | 9606 | BIOGRID |
| UHRF1 | UBE2N | Reconstituted Complex | 30357346 | 9606 | 9606 | BIOGRID |
| UHRF1 | KDM1A | Affinity Capture-Western | 30357346 | 9606 | 9606 | BIOGRID |
| UHRF1 | LIG1 | Co-crystal Structure | 30639225 | 9606 | 9606 | BIOGRID |
| UHRF1 | LIG1 | Protein-peptide | 30639225 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST1H3A | Protein-peptide | 30639225 | 9606 | 9606 | BIOGRID |
| UHRF1 | LIG1 | Two-hybrid | 30639225 | 9606 | 9606 | BIOGRID |
| UHRF1 | UHRF1 | Biochemical Activity | 31481468 | 9606 | 9606 | BIOGRID |
| UHRF1 | UBE2D1 | Reconstituted Complex | 31481468 | 9606 | 9606 | BIOGRID |
| UHRF1 | PARP1 | Affinity Capture-MS | 31964471 | 9606 | 9606 | BIOGRID |
| UHRF1 | MSH2 | Affinity Capture-MS | 31964471 | 9606 | 9606 | BIOGRID |
| UHRF1 | PARP1 | Affinity Capture-Western | 31964471 | 9606 | 9606 | BIOGRID |
| UHRF1 | KIAA0101 | Protein-peptide | 32144273 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST1H3A | Protein-peptide | 32144273 | 9606 | 9606 | BIOGRID |
| UHRF1 | KIAA0101 | Co-crystal Structure | 32144273 | 9606 | 9606 | BIOGRID |
| UHRF1 | KIAA0101 | Biochemical Activity | 32144273 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST1H3A | Biochemical Activity | 30392931 | 9606 | 9606 | BIOGRID |
| UHRF1 | HIST1H3A | Protein-peptide | 32428527 | 9606 | 9606 | BIOGRID |
| UHRF1 | LIG1 | Protein-peptide | 32428527 | 9606 | 9606 | BIOGRID |
| UHRF1 | Dppa3 | Reconstituted Complex | 31018966 | 9606 | 10090 | BIOGRID |
Annotation of UHRF1
TCGA cancer survival map of UHRF1
Expression of UHRF1
Disease information of UHRF1