TcoF overview
TcoF: WWC1
GeneID: 83637
Name: Protein KIBRA
Ensembl: ENSG00000113645
Species: Human
Class: class HC
Family: WW
Disease: 5
Go term: 19
Pathway: 1
Hallmark: --
Super Enhancer:

chr5:167642668-167679171 chr5:167646019-167679323 chr5:167859482-167875631 chr5:167714586-167752730 chr5:167715000-167758278 chr5:167729442-167756404 chr5:167713753-167794120 chr5:167704064-167756963 chr5:167715105-167756990 chr5:167715064-167757054 chr5:167772810-167794709 chr5:167772681-167795109 chr5:167714881-167794161 chr5:167714817-167762432 chr5:167773910-167794678 chr5:167739595-167757271 chr5:167740660-167794538 chr5:167714643-167756978 chr5:167714814-167757727 chr5:167695520-167745190 chr5:167739051-167794675 chr5:167715636-167770061 chr5:167715633-167760070 chr5:167714813-167752541 chr5:167714139-167752527 chr5:167715387-167747437 chr5:167715162-167751767 chr5:167714688-167757599 chr5:167695408-167752878 chr5:167713933-167757029 chr5:167743174-167774565 chr5:167741466-167774732 chr5:167741492-167756943 chr5:167740749-167757356 chr5:167714094-167756774 chr5:167715141-167757012 chr5:167740403-167757226 chr5:167741548-167792685 chr5:167755745-167774452 chr5:167754444-167774782 chr5:167755803-167774841 chr5:167755276-167792867 chr5:167715842-167762800 chr5:167740968-167794838 chr5:167714658-167793340 chr5:167713533-167794389 chr5:167714065-167794475 chr5:167825719-167839768 chr5:167714858-167800330 chr5:167721584-167757012 chr5:167696031-167773232 chr5:167714875-167770918 chr5:167772980-167794371 chr5:167775299-167793302 chr5:167714875-167757283 chr5:167714875-167757283 chr5:167772311-167796225 chr5:167772359-167796711 chr5:167772362-167796541 chr5:167714433-167763324 chr5:167713984-167793363 chr5:167714121-167757252 chr5:167735499-167752581 chr5:167714869-167757297 chr5:167715446-167747600 chr5:167714108-167760205 chr5:167729529-167744717 chr5:167714942-167757226 chr5:167696220-167757653 chr5:167713883-167754093 chr5:167714780-167750821 chr5:167715594-167773368 chr5:167714973-167756683 chr5:167717787-167745881 chr5:167714310-167841942 chr5:167714944-167762597 chr5:167721229-167770440 chr5:167695498-167794217 chr5:167704125-167756941 chr5:167704355-167756869 chr5:167712826-167774271 chr5:167714866-167752805 chr5:167714869-167793907 chr5:167714126-167759700 chr5:167714850-167793332 chr5:167741468-167794460 chr5:167714858-167752662 chr5:167715510-167773471 chr5:167714812-167794353 chr5:167741387-167795147 chr5:167696513-167775997 chr5:167696515-167796728 chr5:167714934-167775715 chr5:167695458-167759488 chr5:167695512-167758735 chr5:167714744-167758750 chr5:167695345-167762602 chr5:167695460-167762828 chr5:167714210-167762952 chr5:167714073-167760097 chr5:167695349-167794368 chr5:167714485-167758891 chr5:167695505-167763075 chr5:167695420-167762748 chr5:167687012-167757175 chr5:167361019-167380815 chr5:167364552-167374974 chr5:167223289-167278865 chr5:167319261-167330362 chr5:167228882-167250361 chr5:167228937-167249868 chr5:167318439-167346751 chr5:167228093-167245878 chr5:167229546-167288988 chr5:167229473-167249761 chr5:167229862-167250059 chr5:167228160-167267608 chr5:167361034-167378844 chr5:167496016-167535226 chr5:167511303-167536502 chr5:167228539-167249742 chr5:167228228-167250615 chr5:167224544-167267025 chr5:167366372-167379474 chr5:167364105-167381175 chr5:167341624-167345579 chr5:167334885-167460064 chr5:167242131-167270604 chr5:167371886-167378356 chr5:167575945-167634117 chr5:167365855-167379173 chr5:167500113-167538024 chr5:167230023-167248042 chr5:167363347-167381253 chr5:167588556-167627417 chr5:167588814-167623611 chr5:167604199-167624201 chr5:167574527-167623822 chr5:167587198-167616097 chr5:167574031-167623571 chr5:167511394-167539020

Enhancer:

chr5:167653270-167654890 chr5:167835660-167836920 chr5:167894970-167895950 chr5:167913550-167915600 chr5:167500130-167502040 chr5:167573270-167574200 chr5:167588450-167589610 chr5:167589760-167590350 chr5:167687420-167689040 chr5:167740580-167741370 chr5:167831000-167832200 chr5:167899310-167901220 chr5:167675380-167677470 chr5:167802600-167803700 chr5:167642280-167643770 chr5:167945070-167946080 chr5:168078460-168079280 chr5:168080660-168082060 chr5:168167710-168168260 chr5:168072880-168075360 chr5:167638750-167640670 chr5:167738030-167738540 chr5:167751620-167752910 chr5:167753510-167754670 chr5:167761120-167762600 chr5:167779810-167781250 chr5:167827910-167830020 chr5:167857230-167858250 chr5:168003940-168006260 chr5:168039880-168040790 chr5:168050940-168052980 chr5:167754920-167756890 chr5:168017520-168019600 chr5:167946310-167946960 chr5:167814500-167816980 chr5:167840120-167840390 chr5:167876290-167876620 chr5:168076790-168077700 chr5:168123440-168125490 chr5:168139360-168140810 chr5:167833330-167835510 chr5:167851070-167852750 chr5:167579620-167581050 chr5:167604440-167606020 chr5:167606200-167607040 chr5:167613040-167615060 chr5:168026100-168028090 chr5:167590830-167593280 chr5:167786640-167788670 chr5:167843060-167843820 chr5:167843990-167846370 chr5:167446940-167447940 chr5:167448030-167448730 chr5:167586560-167586970 chr5:167587290-167587740 chr5:167345210-167346140

Promoter:

chr5:167718656-167899308

 ChIP-seq based regulatory details of WWC1
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
 Downstream target genes of WWC1
 Protein-protein interaction of WWC1
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
WWC1 PRKCZ Two-hybrid 15081397 9606 9606 BIOGRID
WWC1 PRKCZ Reconstituted Complex 15081397 9606 9606 BIOGRID
WWC1 CDC73 Two-hybrid 16169070 9606 9606 BIOGRID
WWC1 LRIF1 Two-hybrid 16169070 9606 9606 BIOGRID
WWC1 DLC1 Affinity Capture-Western 16684779 9606 9606 BIOGRID
WWC1 HIST1H3A Far Western 16684779 9606 9606 BIOGRID
WWC1 LATS1 Affinity Capture-Western 21233212 9606 9606 BIOGRID
WWC1 LATS2 Affinity Capture-Western 21233212 9606 9606 BIOGRID
WWC1 NF2 Affinity Capture-Western 21233212 9606 9606 BIOGRID
WWC1 PTPN14 Affinity Capture-Western 25023289 9606 9606 BIOGRID
WWC1 LATS1 Affinity Capture-Western 25023289 9606 9606 BIOGRID
WWC1 YWHAB Affinity Capture-MS 24366813 9606 9606 BIOGRID
WWC1 YWHAE Affinity Capture-MS 24366813 9606 9606 BIOGRID
WWC1 YWHAH Affinity Capture-MS 24366813 9606 9606 BIOGRID
WWC1 YWHAG Affinity Capture-MS 24366813 9606 9606 BIOGRID
WWC1 YWHAQ Affinity Capture-MS 24366813 9606 9606 BIOGRID
WWC1 AMOT Affinity Capture-MS 24366813 9606 9606 BIOGRID
WWC1 ATAD3A Affinity Capture-MS 24366813 9606 9606 BIOGRID
WWC1 DYNLL1 Affinity Capture-MS 24366813 9606 9606 BIOGRID
WWC1 DYNLL2 Affinity Capture-MS 24366813 9606 9606 BIOGRID
WWC1 EPB41L2 Affinity Capture-MS 24366813 9606 9606 BIOGRID
WWC1 EPB41L3 Affinity Capture-MS 24366813 9606 9606 BIOGRID
WWC1 BTRC Affinity Capture-MS 24366813 9606 9606 BIOGRID
WWC1 FBXW11 Affinity Capture-MS 24366813 9606 9606 BIOGRID
WWC1 PTPN14 Affinity Capture-MS 24366813 9606 9606 BIOGRID
WWC1 WWC2 Two-hybrid 24682284 9606 9606 BIOGRID
WWC1 WWC3 Two-hybrid 24682284 9606 9606 BIOGRID
WWC1 PRKCA Affinity Capture-Western 24682284 9606 9606 BIOGRID
WWC1 LATS2 Affinity Capture-Western 24682284 9606 9606 BIOGRID
WWC1 LATS1 Affinity Capture-Western 24682284 9606 9606 BIOGRID
WWC1 WWC2 Affinity Capture-Western 24682284 9606 9606 BIOGRID
WWC1 WWC3 Affinity Capture-Western 24682284 9606 9606 BIOGRID
WWC1 CIT Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 AMOT Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 USP9X Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 MPDZ Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 INADL Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 RAPGEF6 Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 AMOTL1 Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 MPP5 Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 DLG1 Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 DCTN1 Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 MAEA Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 MYO1C Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 RMND5A Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 PRKCI Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 ARMC8 Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 CPVL Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 LIN7C Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 DAG1 Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 PTPN14 Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 CSNK1E Affinity Capture-MS 28720576 9606 9606 BIOGRID
WWC1 USP9X Affinity Capture-Western 28720576 9606 9606 BIOGRID
WWC1 WWC1 Affinity Capture-Western 18672031 9606 9606 BIOGRID
WWC1 Prkcz Reconstituted Complex 15081397 9606 10116 BIOGRID
 Annotation of WWC1
 TCGA cancer survival map of WWC1


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  WWC1