Irak1 |
cytoplasm |
GO:0005737 |
Irak1 |
cytosol |
GO:0005829 |
Irak1 |
lipid droplet |
GO:0005811 |
Irak1 |
membrane |
GO:0016020 |
Irak1 |
nucleoplasm |
GO:0005654 |
Irak1 |
nucleus |
GO:0005634 |
Irak1 |
plasma membrane |
GO:0005886 |
Irak1 |
protein-containing complex |
GO:0032991 |
Irak1 |
ATP binding |
GO:0005524 |
Irak1 |
heat shock protein binding |
GO:0031072 |
Irak1 |
identical protein binding |
GO:0042802 |
Irak1 |
interleukin-1 receptor binding |
GO:0005149 |
Irak1 |
kinase activity |
GO:0016301 |
Irak1 |
protein heterodimerization activity |
GO:0046982 |
Irak1 |
protein homodimerization activity |
GO:0042803 |
Irak1 |
protein kinase activity |
GO:0004672 |
Irak1 |
protein serine/threonine kinase activity |
GO:0004674 |
Irak1 |
activation of NF-kappaB-inducing kinase activity |
GO:0007250 |
Irak1 |
cellular response to heat |
GO:0034605 |
Irak1 |
cellular response to lipopolysaccharide |
GO:0071222 |
Irak1 |
cytokine-mediated signaling pathway |
GO:0019221 |
Irak1 |
innate immune response |
GO:0045087 |
Irak1 |
interleukin-1-mediated signaling pathway |
GO:0070498 |
Irak1 |
intracellular signal transduction |
GO:0035556 |
Irak1 |
JNK cascade |
GO:0007254 |
Irak1 |
lipopolysaccharide-mediated signaling pathway |
GO:0031663 |
Irak1 |
negative regulation of cholesterol efflux |
GO:0090370 |
Irak1 |
negative regulation of NF-kappaB transcription factor activity |
GO:0032088 |
Irak1 |
negative regulation of transcription, DNA-templated |
GO:0045892 |
Irak1 |
positive regulation of I-kappaB kinase/NF-kappaB signaling |
GO:0043123 |
Irak1 |
positive regulation of JUN kinase activity |
GO:0043507 |
Irak1 |
positive regulation of leukocyte adhesion to vascular endothelial cell |
GO:1904996 |
Irak1 |
positive regulation of MAP kinase activity |
GO:0043406 |
Irak1 |
positive regulation of NF-kappaB transcription factor activity |
GO:0051092 |
Irak1 |
positive regulation of NIK/NF-kappaB signaling |
GO:1901224 |
Irak1 |
positive regulation of smooth muscle cell proliferation |
GO:0048661 |
Irak1 |
positive regulation of type I interferon production |
GO:0032481 |
Irak1 |
protein autophosphorylation |
GO:0046777 |
Irak1 |
protein phosphorylation |
GO:0006468 |
Irak1 |
regulation of cytokine-mediated signaling pathway |
GO:0001959 |
Irak1 |
response to interleukin-1 |
GO:0070555 |
Irak1 |
response to lipopolysaccharide |
GO:0032496 |
Irak1 |
response to peptidoglycan |
GO:0032494 |
Irak1 |
toll-like receptor 2 signaling pathway |
GO:0034134 |
Irak1 |
toll-like receptor 4 signaling pathway |
GO:0034142 |
Irak1 |
type I interferon signaling pathway |
GO:0060337 |