| Ercc2 |
Formation of the closed pre-initiation complex |
IEA |
R-MMU-109639 |
| Ercc2 |
Addition of nucleotides between position +11 and +30 |
IEA |
R-MMU-111264 |
| Ercc2 |
Recruitment of elongation factors to form elongation complex |
IEA |
R-MMU-112379 |
| Ercc2 |
Hypophosphorylation of RNA Pol II CTD by FCP1P protein |
IEA |
R-MMU-112383 |
| Ercc2 |
Addition of nucleotides leads to transcript elongation |
IEA |
R-MMU-112385 |
| Ercc2 |
Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex |
IEA |
R-MMU-113430 |
| Ercc2 |
Formation of the pre-incision complex in GG-NER |
IEA |
R-MMU-5689317 |
| Ercc2 |
Recruitment of XPA and release of CAK |
IEA |
R-MMU-5689861 |
| Ercc2 |
DNA polymerases delta, epsilon or kappa bind the GG-NER site |
IEA |
R-MMU-5690213 |
| Ercc2 |
3'-incision of DNA by ERCC5 (XPG) in GG-NER |
IEA |
R-MMU-5690988 |
| Ercc2 |
5'- incision of DNA by ERCC1:ERCC4 in GG-NER |
IEA |
R-MMU-5690990 |
| Ercc2 |
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER |
IEA |
R-MMU-5690991 |
| Ercc2 |
ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA |
IEA |
R-MMU-5690996 |
| Ercc2 |
TFIIH binds GG-NER site to form a verification complex |
IEA |
R-MMU-5691000 |
| Ercc2 |
CHD1L is recruited to GG-NER site |
IEA |
R-MMU-5696670 |
| Ercc2 |
RNA Pol II initiates transcription from damaged DNA template |
IEA |
R-MMU-6781818 |
| Ercc2 |
Active RNA Pol II complex transcribes lesion-containing DNA template |
IEA |
R-MMU-6781824 |
| Ercc2 |
ERCC8 (CSA) binds stalled RNA Pol II |
IEA |
R-MMU-6781833 |
| Ercc2 |
ERCC6 binds stalled RNA Pol II |
IEA |
R-MMU-6781840 |
| Ercc2 |
ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II |
IEA |
R-MMU-6781867 |
| Ercc2 |
Assembly of the pre-incision complex in TC-NER |
IEA |
R-MMU-6782004 |
| Ercc2 |
UVSSA:USP7 deubiquitinates ERCC6 |
IEA |
R-MMU-6782069 |
| Ercc2 |
ERCC2-facilitated RNA Pol II backtracking in TC-NER |
IEA |
R-MMU-6782131 |
| Ercc2 |
ERCC5 and RPA bind TC-NER site |
IEA |
R-MMU-6782138 |
| Ercc2 |
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER |
IEA |
R-MMU-6782141 |
| Ercc2 |
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER |
IEA |
R-MMU-6782204 |
| Ercc2 |
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER |
IEA |
R-MMU-6782208 |
| Ercc2 |
DNA polymerases delta, epsilon or kappa bind the TC-NER site |
IEA |
R-MMU-6782211 |
| Ercc2 |
3' incision by ERCC5 (XPG) in TC-NER |
IEA |
R-MMU-6782224 |
| Ercc2 |
Ligation of newly synthesized repair patch to incised DNA in TC-NER |
IEA |
R-MMU-6782227 |
| Ercc2 |
SUMOylation of XPC |
IEA |
R-MMU-6790454 |
| Ercc2 |
RNF111 ubiquitinates SUMOylated XPC |
IEA |
R-MMU-6790487 |
| Ercc2 |
CDK12 phosphorylates RNA Pol II CTD at DNA repair genes |
IEA |
R-MMU-6797606 |
| Ercc2 |
CCNK:CDK12 binds RNA Pol II at DNA repair genes |
IEA |
R-MMU-6797616 |
| Ercc2 |
Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter |
IEA |
R-MMU-73758 |
| Ercc2 |
Loss of Rrn3 from RNA Polymerase I promoter escape complex |
IEA |
R-MMU-73769 |
| Ercc2 |
Abortive initiation after formation of the first phosphodiester bond |
IEA |
R-MMU-73946 |
| Ercc2 |
Elongation of pre-rRNA transcript |
IEA |
R-MMU-74986 |
| Ercc2 |
PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box |
IEA |
R-MMU-74993 |
| Ercc2 |
Addition of the third nucleotide on the nascent transcript |
IEA |
R-MMU-75850 |
| Ercc2 |
Abortive Initiation Before Second Transition |
IEA |
R-MMU-75856 |
| Ercc2 |
NTP Binds Active Site of RNA Polymerase II |
IEA |
R-MMU-75861 |
| Ercc2 |
Fall Back to Closed Pre-initiation Complex |
IEA |
R-MMU-75862 |
| Ercc2 |
Newly Formed Phosphodiester Bond Stabilized and PPi Released |
IEA |
R-MMU-75864 |
| Ercc2 |
Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP |
IEA |
R-MMU-75866 |
| Ercc2 |
Addition of the fourth nucleotide on the Nascent Transcript: Second Transition |
IEA |
R-MMU-75869 |
| Ercc2 |
Addition of Nucleotides 5 through 9 on the growing Transcript |
IEA |
R-MMU-75873 |
| Ercc2 |
Abortive Initiation After Second Transition |
IEA |
R-MMU-75891 |
| Ercc2 |
RNA Polymerase II Promoter Opening: First Transition |
IEA |
R-MMU-75949 |
| Ercc2 |
Addition of nucleotides 10 and 11 on the growing transcript: Third Transition |
IEA |
R-MMU-76576 |
| Ercc2 |
Activation of GT |
IEA |
R-MMU-77068 |
| Ercc2 |
RNA Polymerase II CTD (phosphorylated) binds to CE |
IEA |
R-MMU-77069 |
| Ercc2 |
Phosphorylation (Ser5) of RNA pol II CTD |
IEA |
R-MMU-77071 |
| Ercc2 |
SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) |
IEA |
R-MMU-77073 |
| Ercc2 |
Capping complex formation |
IEA |
R-MMU-77077 |
| Ercc2 |
Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme |
IEA |
R-MMU-77078 |
| Ercc2 |
Formation of the CE:GMP intermediate complex |
IEA |
R-MMU-77081 |
| Ercc2 |
Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA |
IEA |
R-MMU-77083 |
| Ercc2 |
Dissociation of transcript with 5'-GMP from GT |
IEA |
R-MMU-77085 |
| Ercc2 |
Methylation of GMP-cap by RNA Methyltransferase |
IEA |
R-MMU-77090 |
| Ercc2 |
Unwinding of DNA for the Nascent Transcript: Second Transition |
IEA |
R-MMU-9613494 |
| Ercc2 |
Unwinding DNA for the nascent transcript |
IEA |
R-MMU-9613497 |
| Ercc2 |
ERCC3-facilitated RNA Pol II backtracking in TC-NER |
IEA |
R-MMU-9684118 |