Fgf1 |
PI3K-containing complexes phosphorylate PIP2 to PIP3 |
IEA |
R-MMU-109699 |
Fgf1 |
FGFR1b binds to FGF |
IEA |
R-MMU-190245 |
Fgf1 |
FGFR1c binds to FGF |
IEA |
R-MMU-190256 |
Fgf1 |
FGFR2c binds to FGF |
IEA |
R-MMU-190258 |
Fgf1 |
FGFR2b binds to FGF |
IEA |
R-MMU-190260 |
Fgf1 |
FGFR3c binds to FGF |
IEA |
R-MMU-190261 |
Fgf1 |
FGFR3b binds to FGF |
IEA |
R-MMU-190263 |
Fgf1 |
FGFR4 binds to FGF |
IEA |
R-MMU-190265 |
Fgf1 |
Autocatalytic phosphorylation of FGFR4 |
IEA |
R-MMU-190326 |
Fgf1 |
Autocatalytic phosphorylation of FGFR3b |
IEA |
R-MMU-190385 |
Fgf1 |
Autocatalytic phosphorylation of FGFR3c |
IEA |
R-MMU-190388 |
Fgf1 |
Autocatalytic phosphorylation of FGFR2b |
IEA |
R-MMU-190408 |
Fgf1 |
Autocatalytic phosphorylation of FGFR2c |
IEA |
R-MMU-190413 |
Fgf1 |
Autocatalytic phosphorylation of FGFR1b |
IEA |
R-MMU-190427 |
Fgf1 |
Autocatalytic phosphorylation of FGFR1c |
IEA |
R-MMU-190429 |
Fgf1 |
PI3K phosphorylates PIP2 to PIP3 |
IEA |
R-MMU-2316434 |
Fgf1 |
Activated FGFR2 phosphorylates PLCG1 |
IEA |
R-MMU-5654147 |
Fgf1 |
p-4Y-PLCG1 dissociates from activated FGFR3 |
IEA |
R-MMU-5654148 |
Fgf1 |
Activated FGFR1 phosphorylates PLCG1 |
IEA |
R-MMU-5654149 |
Fgf1 |
Activated FGFR4 phosphorylates PLCG1 |
IEA |
R-MMU-5654151 |
Fgf1 |
p-4Y-PLCG1 dissociates from activated FGFR2 |
IEA |
R-MMU-5654157 |
Fgf1 |
Activated FGFR2 binds PLCG1 |
IEA |
R-MMU-5654159 |
Fgf1 |
Activated FGFR4 binds PLCG1 |
IEA |
R-MMU-5654163 |
Fgf1 |
p-4Y-PLCG1 dissociates from activated FGFR1 |
IEA |
R-MMU-5654165 |
Fgf1 |
Activated FGFR1 binds PLCG1 |
IEA |
R-MMU-5654167 |
Fgf1 |
p-4Y-PLCG1 dissociates from activated FGFR4 |
IEA |
R-MMU-5654169 |
Fgf1 |
Activated FGFR3 phosphorylates PLCG1 |
IEA |
R-MMU-5654222 |
Fgf1 |
Activated FGFR3 binds PLCG1 |
IEA |
R-MMU-5654224 |
Fgf1 |
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange |
IEA |
R-MMU-5654392 |
Fgf1 |
Activated FGFR2 phosphorylates FRS2 |
IEA |
R-MMU-5654397 |
Fgf1 |
Activated FGFR2 binds FRS2 |
IEA |
R-MMU-5654399 |
Fgf1 |
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange |
IEA |
R-MMU-5654402 |
Fgf1 |
Activated FGFR2 binds SHC1 |
IEA |
R-MMU-5654404 |
Fgf1 |
Activated FGFR2:p-SHC1 binds GRB2:SOS1 |
IEA |
R-MMU-5654406 |
Fgf1 |
Activated FGFR2 phosphorylates SHC1 |
IEA |
R-MMU-5654407 |
Fgf1 |
Activated FGFR3 phosphorylates FRS2 |
IEA |
R-MMU-5654408 |
Fgf1 |
Activated FGFR3 binds FRS2 |
IEA |
R-MMU-5654409 |
Fgf1 |
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange |
IEA |
R-MMU-5654413 |
Fgf1 |
Activated FGFR3:pFRS binds GRB2:SOS1 |
IEA |
R-MMU-5654416 |
Fgf1 |
Activated FGFR4 phosphorylates FRS2 |
IEA |
R-MMU-5654418 |
Fgf1 |
Activated FGFR4 binds FRS2 |
IEA |
R-MMU-5654422 |
Fgf1 |
Activated FGFR4:p-SHC1 binds GRB2:SOS1 |
IEA |
R-MMU-5654423 |
Fgf1 |
Activated FGFR4 binds SHC1 |
IEA |
R-MMU-5654425 |
Fgf1 |
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange |
IEA |
R-MMU-5654426 |
Fgf1 |
Activated FGFR4 phosphorylates SHC1 |
IEA |
R-MMU-5654428 |
Fgf1 |
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. |
IEA |
R-MMU-5654560 |
Fgf1 |
Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 |
IEA |
R-MMU-5654562 |
Fgf1 |
Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. |
IEA |
R-MMU-5654565 |
Fgf1 |
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. |
IEA |
R-MMU-5654566 |
Fgf1 |
Activated FGFR1 binds FRS2 |
IEA |
R-MMU-5654569 |
Fgf1 |
Activated FGFR1 binds FRS3 |
IEA |
R-MMU-5654571 |
Fgf1 |
Activated FGFR1 binds SHC1 |
IEA |
R-MMU-5654573 |
Fgf1 |
Activated FGFR1 phosphorylates FRS2 |
IEA |
R-MMU-5654575 |
Fgf1 |
Activated FGFR1 phosphorylates FRS3 |
IEA |
R-MMU-5654578 |
Fgf1 |
Activated FGFR1 phosphorylates SHC1 |
IEA |
R-MMU-5654582 |
Fgf1 |
Activated FGFR1:p-FRS bind to PPTN11 |
IEA |
R-MMU-5654584 |
Fgf1 |
Activated FGFR1:p-FRS binds GRB2:SOS1 |
IEA |
R-MMU-5654586 |
Fgf1 |
Activated FGFR1:p-FRS phosphorylates PPTN11 |
IEA |
R-MMU-5654587 |
Fgf1 |
Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA |
IEA |
R-MMU-5654591 |
Fgf1 |
Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 |
IEA |
R-MMU-5654592 |
Fgf1 |
Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 |
IEA |
R-MMU-5654594 |
Fgf1 |
Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA |
IEA |
R-MMU-5654596 |
Fgf1 |
Activated FGFR1:p-SHC1 binds GRB2:SOS1 |
IEA |
R-MMU-5654597 |
Fgf1 |
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange |
IEA |
R-MMU-5654600 |
Fgf1 |
Activated FGFR2 binds FRS3 |
IEA |
R-MMU-5654603 |
Fgf1 |
Activated FGFR2 phosphorylates FRS3 |
IEA |
R-MMU-5654605 |
Fgf1 |
Activated FGFR2 phosphorylates PPTN11 |
IEA |
R-MMU-5654607 |
Fgf1 |
Activated FGFR2:p-FRS bind to PPTN11 |
IEA |
R-MMU-5654608 |
Fgf1 |
Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 |
IEA |
R-MMU-5654612 |
Fgf1 |
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA |
IEA |
R-MMU-5654614 |
Fgf1 |
Activated FGFR2:pFRS binds GRB2:SOS1 |
IEA |
R-MMU-5654615 |
Fgf1 |
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange |
IEA |
R-MMU-5654618 |
Fgf1 |
Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 |
IEA |
R-MMU-5654620 |
Fgf1 |
Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA |
IEA |
R-MMU-5654622 |
Fgf1 |
Activated FGFR3 binds FRS3 |
IEA |
R-MMU-5654623 |
Fgf1 |
Activated FGFR3 binds SHC1 |
IEA |
R-MMU-5654625 |
Fgf1 |
Activated FGFR3 phosphorylates FRS3 |
IEA |
R-MMU-5654628 |
Fgf1 |
Activated FGFR3 phosphorylates PPTN11 |
IEA |
R-MMU-5654631 |
Fgf1 |
Activated FGFR3:p-FRS bind to PPTN11 |
IEA |
R-MMU-5654633 |
Fgf1 |
Activated FGFR3 phosphorylates SHC1 |
IEA |
R-MMU-5654634 |
Fgf1 |
Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 |
IEA |
R-MMU-5654637 |
Fgf1 |
Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA |
IEA |
R-MMU-5654640 |
Fgf1 |
Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 |
IEA |
R-MMU-5654641 |
Fgf1 |
Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA |
IEA |
R-MMU-5654643 |
Fgf1 |
Activated FGFR3:p-SHC1 binds GRB2:SOS1 |
IEA |
R-MMU-5654646 |
Fgf1 |
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange |
IEA |
R-MMU-5654647 |
Fgf1 |
Activated FGFR4 binds FRS3 |
IEA |
R-MMU-5654651 |
Fgf1 |
Activated FGFR4 phosphorylates FRS3 |
IEA |
R-MMU-5654653 |
Fgf1 |
Activated FGFR4 phosphorylates PPTN11 |
IEA |
R-MMU-5654655 |
Fgf1 |
Activated FGFR4:p-FRS bind to PPTN11 |
IEA |
R-MMU-5654658 |
Fgf1 |
Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 |
IEA |
R-MMU-5654659 |
Fgf1 |
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA |
IEA |
R-MMU-5654662 |
Fgf1 |
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange |
IEA |
R-MMU-5654663 |
Fgf1 |
Activated FGFR4:p-FRS binds GRB2:SOS1 |
IEA |
R-MMU-5654664 |
Fgf1 |
Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 |
IEA |
R-MMU-5654667 |
Fgf1 |
Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA |
IEA |
R-MMU-5654669 |
Fgf1 |
CBL ubiquitinates FRS2 and FGFR1 |
IEA |
R-MMU-5654672 |
Fgf1 |
p-CBL:GRB2 binds p-FRS2:activated FGFR1 |
IEA |
R-MMU-5654673 |
Fgf1 |
CBL ubiquitinates FRS2 and FGFR2 |
IEA |
R-MMU-5654677 |
Fgf1 |
CBL ubiquitinates FRS2 and FGFR3 |
IEA |
R-MMU-5654679 |
Fgf1 |
CBL ubiquitinates FRS2 and FGFR4 |
IEA |
R-MMU-5654684 |
Fgf1 |
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 |
IEA |
R-MMU-5654690 |
Fgf1 |
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 |
IEA |
R-MMU-5654692 |
Fgf1 |
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 |
IEA |
R-MMU-5654697 |
Fgf1 |
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 |
IEA |
R-MMU-5654701 |
Fgf1 |
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 |
IEA |
R-MMU-5654705 |
Fgf1 |
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 |
IEA |
R-MMU-5654709 |
Fgf1 |
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 |
IEA |
R-MMU-5654714 |
Fgf1 |
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 |
IEA |
R-MMU-5654717 |
Fgf1 |
p-CBL:GRB2 binds p-FRS2:activated FGFR2 |
IEA |
R-MMU-5654729 |
Fgf1 |
p-CBL:GRB2 binds p-FRS2:activated FGFR3 |
IEA |
R-MMU-5654730 |
Fgf1 |
p-CBL:GRB2 binds p-FRS2:activated FGFR4 |
IEA |
R-MMU-5654734 |
Fgf1 |
Activated FGFR1 binds FLRT1,2,3 |
IEA |
R-MMU-5656064 |
Fgf1 |
RAS GEFs promote RAS nucleotide exchange |
IEA |
R-MMU-5672965 |
Fgf1 |
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange |
IEA |
R-MMU-8941613 |
Fgf1 |
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange |
IEA |
R-MMU-8941618 |
Fgf1 |
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange |
IEA |
R-MMU-8941623 |
Fgf1 |
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange |
IEA |
R-MMU-8941628 |