Kat5 |
MRN complex bound to shortened telomeres recruits ATM |
IEA |
R-MMU-5682018 |
Kat5 |
MRN bound to shortened telomeres activates ATM |
IEA |
R-MMU-5682026 |
Kat5 |
KAT5 acetylates ATM at DNA DSBs |
IEA |
R-MMU-5682044 |
Kat5 |
HERC2 and PIAS4 are recruited to DNA DSBs |
IEA |
R-MMU-5682586 |
Kat5 |
RNF8 binds phosphorylated MDC1 at DNA DSBs |
IEA |
R-MMU-5682588 |
Kat5 |
ATM phosphorylates HERC2 |
IEA |
R-MMU-5682598 |
Kat5 |
PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs |
IEA |
R-MMU-5682607 |
Kat5 |
HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 |
IEA |
R-MMU-5682629 |
Kat5 |
RNF8 and RNF168 ubiquitinate H2AFX |
IEA |
R-MMU-5682858 |
Kat5 |
RNF168 binds DNA DSBs |
IEA |
R-MMU-5682863 |
Kat5 |
WHSC1 dimethylates histone H4 on lysine K21 at DSBs |
IEA |
R-MMU-5682965 |
Kat5 |
WHSC1 binds DNA DSBs |
IEA |
R-MMU-5682967 |
Kat5 |
ATM phosphorylates WHSC1 |
IEA |
R-MMU-5682983 |
Kat5 |
KDM4A,B bind H4K20Me2 |
IEA |
R-MMU-5682992 |
Kat5 |
RNF8 and RNF168 ubiquitinate KDM4A,B |
IEA |
R-MMU-5683077 |
Kat5 |
UIMC1 and FAM175A bind DNA DSBs |
IEA |
R-MMU-5683384 |
Kat5 |
PPP5C dephosphorylates TP53BP1 |
IEA |
R-MMU-5683405 |
Kat5 |
ATM phosphorylates TP53BP1 at DNA DSBs |
IEA |
R-MMU-5683425 |
Kat5 |
CHEK2 is recruited to DNA DSBs |
IEA |
R-MMU-5683735 |
Kat5 |
CHEK2 phosphorylates BRCA1 |
IEA |
R-MMU-5683801 |
Kat5 |
ATM phosphorylates EYA1-4 |
IEA |
R-MMU-5683964 |
Kat5 |
EYA1-4 dephosphorylates tyrosine Y142 of H2AFX |
IEA |
R-MMU-5683967 |
Kat5 |
APBB1 and MAPK8 bind diphosphorylated H2AFX |
IEA |
R-MMU-5683986 |
Kat5 |
PIAS4 SUMOylates MDC1 |
IEA |
R-MMU-5684052 |
Kat5 |
MRN complex binds CDK2 and RBBP8 |
IEA |
R-MMU-5684081 |
Kat5 |
CDK2 phosphorylates RBBP8 |
IEA |
R-MMU-5684096 |
Kat5 |
ATM phosphorylates RBBP8 |
IEA |
R-MMU-5684140 |
Kat5 |
Binding of ATR:ATRIP to RPA at resected DNA DSBs |
IEA |
R-MMU-5684875 |
Kat5 |
CHEK1 is recruited to resected DNA DSBs |
IEA |
R-MMU-5684882 |
Kat5 |
Activation of CHEK1 at resected DNA DSBs |
IEA |
R-MMU-5684887 |
Kat5 |
ATR activation at DNA DSBs |
IEA |
R-MMU-5685011 |
Kat5 |
ATR phosphorylates RPA2 |
IEA |
R-MMU-5685156 |
Kat5 |
BCDX2 complex stabilizes RAD51 filament |
IEA |
R-MMU-5685341 |
Kat5 |
CX3 complex binds D-loop structures |
IEA |
R-MMU-5685838 |
Kat5 |
EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment |
IEA |
R-MMU-5685985 |
Kat5 |
Long-range resection of DNA DSBs by EXO1 or DNA2 |
IEA |
R-MMU-5685994 |
Kat5 |
MUS81:EME1,EME2 cleaves D-loop |
IEA |
R-MMU-5686440 |
Kat5 |
RAD52 promotes single strand annealing at resected DNA DSBs |
IEA |
R-MMU-5686642 |
Kat5 |
Activated ATM phosphorylates DCLRE1C |
IEA |
R-MMU-5686704 |
Kat5 |
TP53BP1 recruits DCLRE1C to ATM |
IEA |
R-MMU-5686900 |
Kat5 |
ATM phosphorylates MDC1 |
IEA |
R-MMU-5693536 |
Kat5 |
Ligation of DNA and formation of Holliday structures following repair synthesis |
IEA |
R-MMU-5693539 |
Kat5 |
MRN activates ATM |
IEA |
R-MMU-5693540 |
Kat5 |
Association of RPA complexes with ssDNA at resected DNA DSBs |
IEA |
R-MMU-5693542 |
Kat5 |
ATM phosphorylates histone H2AFX on S139 at DNA DSBs |
IEA |
R-MMU-5693549 |
Kat5 |
Phosphorylation of BRCA1-A complex at multiple sites by ATM |
IEA |
R-MMU-5693551 |
Kat5 |
RAD51 binds BRCA2 at resected DNA DSBs |
IEA |
R-MMU-5693561 |
Kat5 |
Association of RAD51 with RAD52:DNA double-strand break ends |
IEA |
R-MMU-5693564 |
Kat5 |
TP53BP1 associates with H4K20Me2 at DNA DSBs |
IEA |
R-MMU-5693566 |
Kat5 |
Association of RAD52 with the RPA complex at resected DNA DSBs |
IEA |
R-MMU-5693580 |
Kat5 |
MDC1 associates with gamma-H2AFX at nuclear foci |
IEA |
R-MMU-5693583 |
Kat5 |
Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) |
IEA |
R-MMU-5693584 |
Kat5 |
D-loop extension by DNA polymerases |
IEA |
R-MMU-5693593 |
Kat5 |
ATM phosphorylates NBN |
IEA |
R-MMU-5693598 |
Kat5 |
Association of Ku heterodimer with ends of DNA double-strand break |
IEA |
R-MMU-5693599 |
Kat5 |
ATM recognizes H2AFX-Nucleosomes |
IEA |
R-MMU-5693602 |
Kat5 |
Initial resection of double-strand break ends |
IEA |
R-MMU-5693608 |
Kat5 |
MRN complex bound to DNA ends recruits ATM |
IEA |
R-MMU-5693612 |
Kat5 |
D-loop formation mediated by PALB2, BRCA2 and RAD51 |
IEA |
R-MMU-5693620 |
Kat5 |
KAT5 acetylates ATM at shortened telomeres |
IEA |
R-MMU-6792712 |
Kat5 |
ATR phosphorylates TP53 |
IEA |
R-MMU-6799332 |
Kat5 |
Phosphorylation and activation of CHEK2 by ATM |
IEA |
R-MMU-69891 |
Kat5 |
Histone acetyltransferases are recruited to the TFF1 gene |
IEA |
R-MMU-9023860 |