Gene Pathway Pathway_source Pathway_id
Kat5 MRN complex bound to shortened telomeres recruits ATM IEA R-MMU-5682018
Kat5 MRN bound to shortened telomeres activates ATM IEA R-MMU-5682026
Kat5 KAT5 acetylates ATM at DNA DSBs IEA R-MMU-5682044
Kat5 HERC2 and PIAS4 are recruited to DNA DSBs IEA R-MMU-5682586
Kat5 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA R-MMU-5682588
Kat5 ATM phosphorylates HERC2 IEA R-MMU-5682598
Kat5 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA R-MMU-5682607
Kat5 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA R-MMU-5682629
Kat5 RNF8 and RNF168 ubiquitinate H2AFX IEA R-MMU-5682858
Kat5 RNF168 binds DNA DSBs IEA R-MMU-5682863
Kat5 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA R-MMU-5682965
Kat5 WHSC1 binds DNA DSBs IEA R-MMU-5682967
Kat5 ATM phosphorylates WHSC1 IEA R-MMU-5682983
Kat5 KDM4A,B bind H4K20Me2 IEA R-MMU-5682992
Kat5 RNF8 and RNF168 ubiquitinate KDM4A,B IEA R-MMU-5683077
Kat5 UIMC1 and FAM175A bind DNA DSBs IEA R-MMU-5683384
Kat5 PPP5C dephosphorylates TP53BP1 IEA R-MMU-5683405
Kat5 ATM phosphorylates TP53BP1 at DNA DSBs IEA R-MMU-5683425
Kat5 CHEK2 is recruited to DNA DSBs IEA R-MMU-5683735
Kat5 CHEK2 phosphorylates BRCA1 IEA R-MMU-5683801
Kat5 ATM phosphorylates EYA1-4 IEA R-MMU-5683964
Kat5 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA R-MMU-5683967
Kat5 APBB1 and MAPK8 bind diphosphorylated H2AFX IEA R-MMU-5683986
Kat5 PIAS4 SUMOylates MDC1 IEA R-MMU-5684052
Kat5 MRN complex binds CDK2 and RBBP8 IEA R-MMU-5684081
Kat5 CDK2 phosphorylates RBBP8 IEA R-MMU-5684096
Kat5 ATM phosphorylates RBBP8 IEA R-MMU-5684140
Kat5 Binding of ATR:ATRIP to RPA at resected DNA DSBs IEA R-MMU-5684875
Kat5 CHEK1 is recruited to resected DNA DSBs IEA R-MMU-5684882
Kat5 Activation of CHEK1 at resected DNA DSBs IEA R-MMU-5684887
Kat5 ATR activation at DNA DSBs IEA R-MMU-5685011
Kat5 ATR phosphorylates RPA2 IEA R-MMU-5685156
Kat5 BCDX2 complex stabilizes RAD51 filament IEA R-MMU-5685341
Kat5 CX3 complex binds D-loop structures IEA R-MMU-5685838
Kat5 EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment IEA R-MMU-5685985
Kat5 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA R-MMU-5685994
Kat5 MUS81:EME1,EME2 cleaves D-loop IEA R-MMU-5686440
Kat5 RAD52 promotes single strand annealing at resected DNA DSBs IEA R-MMU-5686642
Kat5 Activated ATM phosphorylates DCLRE1C IEA R-MMU-5686704
Kat5 TP53BP1 recruits DCLRE1C to ATM IEA R-MMU-5686900
Kat5 ATM phosphorylates MDC1 IEA R-MMU-5693536
Kat5 Ligation of DNA and formation of Holliday structures following repair synthesis IEA R-MMU-5693539
Kat5 MRN activates ATM IEA R-MMU-5693540
Kat5 Association of RPA complexes with ssDNA at resected DNA DSBs IEA R-MMU-5693542
Kat5 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA R-MMU-5693549
Kat5 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA R-MMU-5693551
Kat5 RAD51 binds BRCA2 at resected DNA DSBs IEA R-MMU-5693561
Kat5 Association of RAD51 with RAD52:DNA double-strand break ends IEA R-MMU-5693564
Kat5 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA R-MMU-5693566
Kat5 Association of RAD52 with the RPA complex at resected DNA DSBs IEA R-MMU-5693580
Kat5 MDC1 associates with gamma-H2AFX at nuclear foci IEA R-MMU-5693583
Kat5 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA R-MMU-5693584
Kat5 D-loop extension by DNA polymerases IEA R-MMU-5693593
Kat5 ATM phosphorylates NBN IEA R-MMU-5693598
Kat5 Association of Ku heterodimer with ends of DNA double-strand break IEA R-MMU-5693599
Kat5 ATM recognizes H2AFX-Nucleosomes IEA R-MMU-5693602
Kat5 Initial resection of double-strand break ends IEA R-MMU-5693608
Kat5 MRN complex bound to DNA ends recruits ATM IEA R-MMU-5693612
Kat5 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA R-MMU-5693620
Kat5 KAT5 acetylates ATM at shortened telomeres IEA R-MMU-6792712
Kat5 ATR phosphorylates TP53 IEA R-MMU-6799332
Kat5 Phosphorylation and activation of CHEK2 by ATM IEA R-MMU-69891
Kat5 Histone acetyltransferases are recruited to the TFF1 gene IEA R-MMU-9023860