| Orc2 |
Activation of claspin |
IEA |
R-MMU-176298 |
| Orc2 |
Loading of claspin onto DNA during replication origin firing |
IEA |
R-MMU-176318 |
| Orc2 |
Association of MCM8 with ORC:origin complex |
IEA |
R-MMU-176973 |
| Orc2 |
Orc3 associates with Orc2 constitutively bound at origins of replication |
IEA |
R-MMU-68595 |
| Orc2 |
Orc5 associates with Orc3:Orc2:origin complexes |
IEA |
R-MMU-68603 |
| Orc2 |
Orc4 associates with Orc5:Orc3:Orc2:origin complexes |
IEA |
R-MMU-68610 |
| Orc2 |
Orc1 associates with Orc4:Orc5:Orc3:Orc2:origin complexes |
IEA |
R-MMU-68611 |
| Orc2 |
Orc6 associates with Orc1:Orc4:Orc5:Orc3:Orc2:origin complexes, forming ORC:origin complexes |
IEA |
R-MMU-68615 |
| Orc2 |
CDC6 association with ORC:origin complexes mediated by MCM8 |
IEA |
R-MMU-68688 |
| Orc2 |
Free CDT1 associates with CDC6:ORC:origin complexes |
IEA |
R-MMU-68826 |
| Orc2 |
Mcm2-7 associates with the Cdt1:CDC6:ORC:origin complex, forming the pre-replicative complex (preRC) |
IEA |
R-MMU-68849 |
| Orc2 |
DNA polymerase alpha:primase binds at the origin |
IEA |
R-MMU-68914 |
| Orc2 |
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin |
IEA |
R-MMU-68916 |
| Orc2 |
Cdc45 associates with the pre-replicative complex at the origin |
IEA |
R-MMU-68917 |
| Orc2 |
CDK and DDK associate with the Mcm10:pre-replicative complex |
IEA |
R-MMU-68918 |
| Orc2 |
Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 |
IEA |
R-MMU-68919 |
| Orc2 |
Cdt1 is displaced from the pre-replicative complex. |
IEA |
R-MMU-68940 |
| Orc2 |
Orc1 is phosphorylated by cyclin A/CDK2 |
IEA |
R-MMU-68944 |
| Orc2 |
DNA polymerase epsilon binds at the origin |
IEA |
R-MMU-68960 |