| Rbx1 |
Prolactin receptor is internalized |
IEA |
R-MMU-1170539 |
| Rbx1 |
Proteasome proteolyzes ub-HIF-alpha |
IEA |
R-MMU-1234159 |
| Rbx1 |
Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha |
IEA |
R-MMU-1234163 |
| Rbx1 |
Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha |
IEA |
R-MMU-1234169 |
| Rbx1 |
Nuclear VBC complex ubiquitinylates HIF-alpha |
IEA |
R-MMU-1234172 |
| Rbx1 |
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A |
IEA |
R-MMU-1234173 |
| Rbx1 |
ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol |
IEA |
R-MMU-1234175 |
| Rbx1 |
ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol |
IEA |
R-MMU-1234175 |
| Rbx1 |
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A |
IEA |
R-MMU-1234177 |
| Rbx1 |
Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha |
IEA |
R-MMU-1234183 |
| Rbx1 |
PRLR binds SCF beta-TrCP complex |
IEA |
R-MMU-1370500 |
| Rbx1 |
DVL is ubiquitinated by CUL3:KLHL12:RBX1 |
IEA |
R-MMU-1504190 |
| Rbx1 |
Ubiquitinated DVL is degraded by the proteasome |
IEA |
R-MMU-1504193 |
| Rbx1 |
DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex |
IEA |
R-MMU-1504213 |
| Rbx1 |
Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex |
IEA |
R-MMU-209063 |
| Rbx1 |
SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex |
IEA |
R-MMU-209125 |
| Rbx1 |
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex |
IEA |
R-MMU-2130279 |
| Rbx1 |
Degradation of ubiquitinated beta catenin by the proteasome |
IEA |
R-MMU-2130282 |
| Rbx1 |
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) |
IEA |
R-MMU-2130286 |
| Rbx1 |
SCF(beta-TrCP) ubiquitinates p-GLI1 |
IEA |
R-MMU-5610742 |
| Rbx1 |
SCF(beta-TrCP) ubiquitinates p-GLI3 |
IEA |
R-MMU-5610746 |
| Rbx1 |
GLI2,3 are degraded by the proteasome |
IEA |
R-MMU-5635854 |
| Rbx1 |
phosphorylated GLI proteins bind SPOP:CUL3:RBX1 |
IEA |
R-MMU-5635855 |
| Rbx1 |
SPOP:CUL3:RBX1 ubiquitinates GLI2,3 |
IEA |
R-MMU-5635856 |
| Rbx1 |
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA |
IEA |
R-MMU-5652005 |
| Rbx1 |
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA |
IEA |
R-MMU-5652009 |
| Rbx1 |
KBTBD7:CUL3:RBX1 ubiquitinates NF1 |
IEA |
R-MMU-5658424 |
| Rbx1 |
Formation of the pre-incision complex in GG-NER |
IEA |
R-MMU-5689317 |
| Rbx1 |
Recruitment of XPA and release of CAK |
IEA |
R-MMU-5689861 |
| Rbx1 |
DNA polymerases delta, epsilon or kappa bind the GG-NER site |
IEA |
R-MMU-5690213 |
| Rbx1 |
3'-incision of DNA by ERCC5 (XPG) in GG-NER |
IEA |
R-MMU-5690988 |
| Rbx1 |
5'- incision of DNA by ERCC1:ERCC4 in GG-NER |
IEA |
R-MMU-5690990 |
| Rbx1 |
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER |
IEA |
R-MMU-5690991 |
| Rbx1 |
ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA |
IEA |
R-MMU-5690996 |
| Rbx1 |
TFIIH binds GG-NER site to form a verification complex |
IEA |
R-MMU-5691000 |
| Rbx1 |
XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site |
IEA |
R-MMU-5691006 |
| Rbx1 |
PARP1 or PARP2 PARylates DDB2 and autoPARylates |
IEA |
R-MMU-5696655 |
| Rbx1 |
PARP1 or PARP2 binds DDB2 at GG-NER site |
IEA |
R-MMU-5696664 |
| Rbx1 |
CHD1L is recruited to GG-NER site |
IEA |
R-MMU-5696670 |
| Rbx1 |
ERCC8 (CSA) binds stalled RNA Pol II |
IEA |
R-MMU-6781833 |
| Rbx1 |
ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II |
IEA |
R-MMU-6781867 |
| Rbx1 |
Assembly of the pre-incision complex in TC-NER |
IEA |
R-MMU-6782004 |
| Rbx1 |
UVSSA:USP7 deubiquitinates ERCC6 |
IEA |
R-MMU-6782069 |
| Rbx1 |
ERCC2-facilitated RNA Pol II backtracking in TC-NER |
IEA |
R-MMU-6782131 |
| Rbx1 |
ERCC5 and RPA bind TC-NER site |
IEA |
R-MMU-6782138 |
| Rbx1 |
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER |
IEA |
R-MMU-6782141 |
| Rbx1 |
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER |
IEA |
R-MMU-6782204 |
| Rbx1 |
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER |
IEA |
R-MMU-6782208 |
| Rbx1 |
DNA polymerases delta, epsilon or kappa bind the TC-NER site |
IEA |
R-MMU-6782211 |
| Rbx1 |
3' incision by ERCC5 (XPG) in TC-NER |
IEA |
R-MMU-6782224 |
| Rbx1 |
Ligation of newly synthesized repair patch to incised DNA in TC-NER |
IEA |
R-MMU-6782227 |
| Rbx1 |
UV-DDB ubiquitinates XPC |
IEA |
R-MMU-6782943 |
| Rbx1 |
SUMOylation of XPC |
IEA |
R-MMU-6790454 |
| Rbx1 |
RNF111 ubiquitinates SUMOylated XPC |
IEA |
R-MMU-6790487 |
| Rbx1 |
Phosphorylated Orc1 is ubiquitinated while still associated with chromatin |
IEA |
R-MMU-68946 |
| Rbx1 |
SCF:FBXL7 binds AURKA |
IEA |
R-MMU-8853496 |
| Rbx1 |
SCF-FBXL7 ubiquitinates AURKA |
IEA |
R-MMU-8854041 |
| Rbx1 |
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 |
IEA |
R-MMU-8854044 |
| Rbx1 |
SCF-FBXL18 ubiquitinates FBXL7 |
IEA |
R-MMU-8854051 |
| Rbx1 |
Formation of the SCF-FBXL7 complex |
IEA |
R-MMU-8854052 |
| Rbx1 |
SCF(SKP2) complex binds RUNX2 |
IEA |
R-MMU-8939688 |
| Rbx1 |
SCF(SKP2) polyubiquitinates RUNX2 |
IEA |
R-MMU-8939706 |
| Rbx1 |
AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex |
IEA |
R-MMU-8952618 |
| Rbx1 |
NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex |
IEA |
R-MMU-8952620 |
| Rbx1 |
AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex |
IEA |
R-MMU-8952638 |
| Rbx1 |
NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex |
IEA |
R-MMU-8952639 |
| Rbx1 |
CAND1 binds cytosolic CRL E3 ubiquitin ligases |
IEA |
R-MMU-8955241 |
| Rbx1 |
CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus |
IEA |
R-MMU-8955245 |
| Rbx1 |
COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex |
IEA |
R-MMU-8955285 |
| Rbx1 |
COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes |
IEA |
R-MMU-8955289 |
| Rbx1 |
AcM-UBE2M transfers NEDD8 to CUL9:RBX1 |
IEA |
R-MMU-8956025 |
| Rbx1 |
CUL9:RBX1 ubiquitinates BIRC5 |
IEA |
R-MMU-8956026 |
| Rbx1 |
NEDD8:AcM-UBE2M binds CUL9:RBX1 ubiquitin ligase complex |
IEA |
R-MMU-8956031 |
| Rbx1 |
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes |
IEA |
R-MMU-8956040 |
| Rbx1 |
COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex |
IEA |
R-MMU-8956045 |
| Rbx1 |
NEDD8-CUL9:RBX1 binds CUL7:CCDC8:OBSL1 |
IEA |
R-MMU-8956050 |
| Rbx1 |
VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 |
IEA |
R-MMU-8956099 |
| Rbx1 |
VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha |
IEA |
R-MMU-8956103 |
| Rbx1 |
VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha |
IEA |
R-MMU-8956106 |
| Rbx1 |
MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex |
IEA |
R-MMU-8956200 |
| Rbx1 |
Fbxw7 binds Runx2 and Gsk3b |
TAS |
R-MMU-9008677 |
| Rbx1 |
Fbxw7 polyubiquitinates Runx2 |
TAS |
R-MMU-9008715 |
| Rbx1 |
Proteasome degrades polyubiquitinated Runx2 |
TAS |
R-MMU-9008717 |
| Rbx1 |
ERCC3-facilitated RNA Pol II backtracking in TC-NER |
IEA |
R-MMU-9684118 |
| Rbx1 |
Prolactin receptor ligands bind the prolactin receptor |
IEA |
R-MMU-976991 |
| Rbx1 |
Transfer of Ub from E2 to substrate and release of E2 |
IEA |
R-MMU-983140 |
| Rbx1 |
Release of E3 from polyubiquitinated substrate |
IEA |
R-MMU-983147 |
| Rbx1 |
Polyubiquitination of substrate |
IEA |
R-MMU-983156 |
| Rbx1 |
Interaction of E3 with substrate and E2-Ub complex |
IEA |
R-MMU-983157 |