Gene Pathway Pathway_source Pathway_id
Rnf8 HERC2 and PIAS4 are recruited to DNA DSBs IEA R-MMU-5682586
Rnf8 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA R-MMU-5682588
Rnf8 ATM phosphorylates HERC2 IEA R-MMU-5682598
Rnf8 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA R-MMU-5682607
Rnf8 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA R-MMU-5682629
Rnf8 RNF8 and RNF168 ubiquitinate H2AFX IEA R-MMU-5682858
Rnf8 RNF168 binds DNA DSBs IEA R-MMU-5682863
Rnf8 RNF8 and RNF168 ubiquitinate KDM4A,B IEA R-MMU-5683077
Rnf8 UIMC1 and FAM175A bind DNA DSBs IEA R-MMU-5683384
Rnf8 PPP5C dephosphorylates TP53BP1 IEA R-MMU-5683405
Rnf8 ATM phosphorylates TP53BP1 at DNA DSBs IEA R-MMU-5683425
Rnf8 CHEK2 is recruited to DNA DSBs IEA R-MMU-5683735
Rnf8 CHEK2 phosphorylates BRCA1 IEA R-MMU-5683801
Rnf8 PIAS4 SUMOylates MDC1 IEA R-MMU-5684052
Rnf8 Activated ATM phosphorylates DCLRE1C IEA R-MMU-5686704
Rnf8 TP53BP1 recruits DCLRE1C to ATM IEA R-MMU-5686900
Rnf8 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA R-MMU-5693551
Rnf8 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA R-MMU-5693566
Rnf8 Association of Ku heterodimer with ends of DNA double-strand break IEA R-MMU-5693599
Rnf8 Phosphorylation and activation of CHEK2 by ATM IEA R-MMU-69891