TcoF overview
| TcoF: | Itch | |
| GeneID: | 16396 | |
| Name: | E3 ubiquitin-protein ligase Itchy | |
| Ensembl: | ENSMUSG00000027598 | |
| Species: | Mouse | |
| Class: | class HC | |
| Family: | Others | |
| Disease: | -- | |
| Go-trem: | 39 | |
| Pathway: | 18 | |
| Super Enhancer: | chr2:155140024-155141565 chr2:155203450-155204151 chr2:155168710-155169062 chr2:155138216-155141497 chr2:155143757-155144508 chr2:155203510-155204207 chr2:155168575-155169611 chr2:155203299-155204338 chr2:155141975-155142407 |
|
| Enhancer: |
chr2:154493180-154505350 chr2:154646820-154658600 chr2:154714600-154718420 chr2:154741560-154742360 chr2:154863380-154864670 chr2:154874950-154876360 chr2:154895900-154900100 chr2:154924740-154924840 chr2:154924970-154925760 chr2:155144600-155148080 chr2:155156990-155157980 chr2:155160580-155161090 chr2:155161150-155162320 chr2:155182660-155183000 chr2:155211200-155211610 chr2:155216950-155218000 chr2:155364380-155367900 chr2:155415100-155418420 chr2:155073670-155075150 chr2:155154410-155156880 chr2:155511150-155517870 chr2:154899740-154900050 chr2:154617280-154618900 chr2:154717020-154718420 chr2:154717810-154718420 chr2:154876140-154876360 chr2:155182900-155183000 chr2:154617280-154617810 chr2:154876110-154876360 chr2:154899470-154900100 chr2:155182680-155183000 chr2:155207750-155208580 chr2:154617460-154618290 chr2:154717860-154718420 chr2:154899840-154900100 chr2:155102380-155102690 chr2:155102740-155102830 chr2:154716840-154718420 chr2:154858080-154868430 chr2:154871820-154873410 chr2:154873470-154876360 chr2:154896760-154900100 chr2:155102940-155103210 chr2:154876740-154879210 chr2:154716820-154718420 chr2:154898820-154900100 chr2:154875420-154876360 chr2:154898570-154900100 chr2:154876740-154877810 chr2:154717500-154718420 chr2:154875260-154876360 chr2:154898600-154900100 chr2:155103800-155103980 chr2:155104380-155105650 chr2:154876740-154877970 chr2:154896250-154900100 chr2:154876740-154877390 chr2:154717930-154718420 chr2:154876130-154876360 chr2:155182790-155183000 chr2:155207750-155208520 chr2:154876740-154879280 chr2:154717310-154718420 chr2:154875770-154876360 chr2:154876740-154878020 chr2:154875820-154876360 chr2:154899290-154900100 chr2:154916180-154917890 chr2:155182740-155183000 chr2:154876740-154877260 chr2:154617280-154618000 chr2:154715170-154718420 chr2:154875750-154876360 chr2:154899390-154900100 chr2:154714830-154718420 chr2:154875730-154876360 chr2:154899150-154900100 chr2:154876740-154878250 chr2:154875670-154876360 chr2:154875760-154876360 chr2:154876740-154877820 chr2:154798020-154798760 chr2:154873070-154873410 chr2:154899100-154900100 chr2:155102380-155102680 chr2:154876740-154882100 chr2:154617280-154626550 chr2:154875680-154876360 chr2:154897960-154900100 chr2:154876740-154879250 chr2:154875690-154876360 chr2:154876740-154878750 chr2:154718120-154718420 chr2:154876030-154876360 chr2:154876740-154877550 chr2:154717730-154718420 chr2:155124920-155126050 chr2:155207750-155209690 chr2:154717110-154718420 chr2:154747980-154748660 chr2:154766760-154769440 chr2:154875710-154876360 chr2:154898520-154900100 chr2:155104380-155106130 chr2:155124920-155126180 chr2:155146330-155146690 chr2:155211900-155212270 chr2:155215580-155216390 chr2:155436990-155437320 chr2:154876740-154877990 chr2:155207750-155207910 chr2:154875810-154876360 chr2:154899200-154900100 chr2:155102940-155103080 chr2:155182700-155183000 chr2:154875950-154876360 chr2:155207750-155208910 chr2:154714090-154718420 chr2:154875500-154876360 chr2:154894750-154900100 chr2:154876740-154879300 chr2:154916420-154917960 chr2:154919020-154919600 chr2:154910230-154910730 chr2:154617280-154619200 chr2:154875600-154876360 chr2:154898400-154900100 chr2:154915400-154918400 chr2:155119000-155122810 chr2:155140330-155147400 chr2:155207750-155209800 chr2:154876740-154879400 chr2:155139400-155140230 chr2:154574560-154575900 chr2:154617280-154617980 chr2:154753680-154754590 chr2:154766950-154767660 chr2:154774800-154777110 chr2:154797410-154798000 chr2:154798080-154799220 chr2:154873050-154873410 chr2:154899460-154900100 chr2:155207750-155208340 chr2:155220240-155220840 chr2:154617280-154618290 chr2:154717790-154718420 chr2:154751500-154752100 chr2:154766840-154768750 chr2:154798120-154798990 chr2:154873240-154873410 chr2:154873470-154874010 chr2:154898700-154900100 chr2:155207750-155209150 chr2:154502220-154504480 chr2:154617280-154621430 chr2:154875840-154876360 chr2:154896100-154900100 chr2:154916340-154917950 chr2:154876780-154877200 chr2:154717010-154718420 chr2:154875880-154876360 chr2:154898560-154900100 chr2:154875780-154876360 chr2:154899820-154900100 chr2:155124920-155126270 chr2:155154760-155156880 chr2:155125380-155125680 chr2:155156990-155157430 chr2:154876740-154877890 chr2:155156530-155156880 chr2:154852790-154854080 chr2:154875470-154876360 chr2:154895980-154900100 chr2:155047550-155050100 chr2:154876740-154877920 chr2:155073670-155075650 chr2:154617280-154619670 chr2:154628340-154629540 chr2:154629590-154630150 chr2:154657180-154659270 chr2:154715060-154718420 chr2:154852860-154854030 chr2:154898090-154900100 chr2:154913840-154914740 chr2:154916470-154918060 chr2:154918180-154919780 chr2:155159380-155160430 chr2:155207750-155208850 chr2:155226000-155226400 chr2:155378150-155379850 chr2:154876740-154878140 chr2:154617280-154618280 chr2:154717000-154718420 chr2:154875720-154876360 chr2:154876740-154877680 chr2:154863420-154864440 chr2:154875830-154876360 chr2:154876740-154877360 chr2:154898500-154900100 chr2:155207750-155209630 chr2:154875960-154876360 chr2:154899640-154900100 chr2:154878250-154878850 chr2:154717340-154718420 chr2:154875850-154876360 chr2:154899530-154900100 chr2:154876740-154877710 chr2:155704420-155705480 chr2:155104380-155105870 chr2:155118560-155122810 chr2:155124920-155126930 chr2:154876740-154879260 chr2:155122940-155124780 chr2:154617280-154620470 chr2:154715300-154718420 chr2:154873040-154873410 chr2:154897980-154900100 chr2:155104380-155104820 chr2:154876740-154878160 chr2:154876000-154876360 chr2:154899650-154900100 chr2:155182780-155183000 chr2:155207750-155208320 chr2:154875650-154876360 chr2:154899540-154900100 chr2:154844550-154845970 chr2:154716730-154718420 chr2:154895210-154900100 chr2:155103800-155103900 chr2:155120960-155121890 chr2:155339200-155340360 chr2:155416810-155418420 chr2:154863500-154865330 chr2:154872550-154873360 chr2:154899590-154900100 chr2:154876740-154877120 chr2:154873060-154873410 chr2:154873470-154874120 chr2:154899600-154900100 chr2:154717800-154718420 chr2:154899050-154900100 chr2:155104380-155106080 chr2:154876740-154877040 chr2:154875740-154876360 chr2:154876740-154877650 chr2:155145600-155147370 chr2:155207750-155209860 chr2:155216950-155218710 chr2:154717960-154718420 chr2:154916770-154917370 chr2:154877410-154877780 |
|
| Promoter: |
chr2:155131480-155135480 |
ChIP-seq based regulatory details of Itch
| Sample ID | Experiment target | Biosample term name | Cell type | Tissue type | Source |
|---|
Downstream target genes of Itch
Protein-protein interaction of Itch
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| Itch | Junb | Affinity Capture-Western | 16387660 | 10090 | 10090 | BIOGRID |
| Itch | Cflar | Reconstituted Complex | 16469705 | 10090 | 10090 | BIOGRID |
| Itch | Cyld | Affinity Capture-Western | 22057290 | 10090 | 10090 | BIOGRID |
| Itch | Ptpn11 | Affinity Capture-Western | 20417562 | 10090 | 10090 | BIOGRID |
| Itch | Ndfip1 | Affinity Capture-Western | 17137798 | 10090 | 10090 | BIOGRID |
| Itch | Notch1 | Biochemical Activity | 10940313 | 10090 | 10090 | BIOGRID |
| Itch | UBE2L3 | Reconstituted Complex | 10940313 | 10090 | 9606 | BIOGRID |
| Itch | Notch1 | Reconstituted Complex | 10940313 | 10090 | 10090 | BIOGRID |
| Itch | Notch1 | Affinity Capture-Western | 10940313 | 10090 | 10090 | BIOGRID |
| Itch | Tab1 | Affinity Capture-MS | 25714464 | 10090 | 10090 | BIOGRID |
| Itch | Tab1 | Affinity Capture-Western | 25714464 | 10090 | 10090 | BIOGRID |
| Itch | Rorc | Affinity Capture-Western | 27322655 | 10090 | 10090 | BIOGRID |
| Itch | 4930506M07Rik | Affinity Capture-Western | 28981589 | 10090 | 10090 | BIOGRID |
| Itch | Ybx1 | Affinity Capture-MS | 28612841 | 10090 | 10090 | BIOGRID |
| Itch | Ifitm3 | Affinity Capture-MS | 28612841 | 10090 | 10090 | BIOGRID |
| Itch | Mcpt9 | Affinity Capture-MS | 28612841 | 10090 | 10090 | BIOGRID |
| Itch | Tgfb1i1 | Affinity Capture-MS | 28612841 | 10090 | 10090 | BIOGRID |
| Itch | Mcptl | Affinity Capture-MS | 28612841 | 10090 | 10090 | BIOGRID |
| Itch | Tgfb1i1 | Affinity Capture-Western | 28612841 | 10090 | 10090 | BIOGRID |
| Itch | Tgfb1i1 | Reconstituted Complex | 28612841 | 10090 | 10090 | BIOGRID |
| Itch | Sufu | Affinity Capture-Western | 29515120 | 10090 | 10090 | BIOGRID |
| Itch | Arrb2 | Affinity Capture-Western | 29515120 | 10090 | 10116 | BIOGRID |
| Itch | Arrb2 | Affinity Capture-Western | 29515120 | 10090 | 10090 | BIOGRID |
| Itch | Fbxl15 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Itch | Hgs | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Itch | Arhgef7 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Itch | Arr3 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Itch | Arrb2 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Itch | Dazap1 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Itch | Hnrnpl | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Itch | Mavs | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Itch | Numb | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Itch | Rpap3 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Itch | Tollip | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Itch | Usp12 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Itch | Cstf1 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Itch | Scnn1b | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
Annotation of Itch
Expression of Itch
Disease information of Itch