TcoF overview
| TcoF: | Lrrk2 | |
| GeneID: | 66725 | |
| Name: | Leucine-rich repeat serine/threonine-protein kinase 2 | |
| Ensembl: | ENSMUSG00000036273 | |
| Species: | Mouse | |
| Class: | NA | |
| Family: | Other_CRF | |
| Disease: | -- | |
| Go-trem: | 163 | |
| Pathway: | 3 | |
| Super Enhancer: | chr15:91632639-91661237 chr15:91686124-91687031 chr15:91703007-91703814 chr15:91702777-91704270 chr15:91614809-91616353 chr15:91651301-91652352 chr15:91702904-91704099 chr15:91612447-91616372 chr15:91702811-91704105 chr15:91612423-91616398 chr15:91753733-91754526 chr15:91690450-91704292 chr15:91614613-91629604 chr15:91651114-91651804 chr15:91735131-91735954 chr15:91772166-91772874 chr15:91613657-91614467 chr15:91613640-91614824 chr15:91703105-91703822 chr15:91787684-91788714 chr15:91633046-91644867 chr15:91686083-91687101 chr15:91642254-91644060 chr15:91702876-91704009 chr15:91660265-91661122 chr15:91613615-91614792 chr15:91613666-91615130 chr15:91703019-91703833 chr15:91615773-91616507 chr15:91660346-91661026 chr15:91632011-91644850 chr15:91657777-91661848 chr15:91679252-91681441 chr15:91702945-91703702 chr15:91610635-91611311 chr15:91632842-91644172 chr15:91660065-91665281 chr15:91642588-91644134 chr15:91702798-91703697 |
|
| Enhancer: |
chr15:91402810-91403000 chr15:91430580-91432350 chr15:91444680-91447980 chr15:91531650-91532600 chr15:91454600-91456450 chr15:91333540-91334110 chr15:91473840-91474440 chr15:91303630-91305380 chr15:91400460-91403000 chr15:91442450-91448550 chr15:91473970-91474850 chr15:91444880-91445870 chr15:91472060-91486080 chr15:91487780-91492810 chr15:91452410-91456360 chr15:91694410-91694860 chr15:91463410-91463920 chr15:91490760-91491960 chr15:91402850-91403000 chr15:91446340-91447040 chr15:91488200-91489330 chr15:91471400-91475600 chr15:91655310-91656800 chr15:91402630-91403000 chr15:91332740-91333440 chr15:91402650-91403000 chr15:91471990-91475090 chr15:91488980-91492850 chr15:91473390-91475290 chr15:91490770-91491880 chr15:91402520-91403000 chr15:91694390-91694920 chr15:91445080-91446810 chr15:91491230-91491830 chr15:91473440-91474950 chr15:91472030-91474990 chr15:91463360-91465510 chr15:91473820-91475050 chr15:91488340-91489340 chr15:91516780-91517240 |
|
| Promoter: |
chr15:91671223-91675223 |
ChIP-seq based regulatory details of Lrrk2
| Sample ID | Experiment target | Biosample term name | Cell type | Tissue type | Source |
|---|
Downstream target genes of Lrrk2
Protein-protein interaction of Lrrk2
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| Lrrk2 | Taok1 | Biochemical Activity | 20949042 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Hsp90aa1 | Affinity Capture-MS | 18367605 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Hsp90aa1 | Affinity Capture-Western | 18367605 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Cdc37 | Affinity Capture-Western | 18367605 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Arhgef7 | Co-localization | 21048939 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Cdc42 | Co-localization | 21048939 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Fis1 | Affinity Capture-Western | 22639965 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Dnm1l | Affinity Capture-Western | 22639965 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Ywhaq | Affinity Capture-Western | 20659021 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Lrrk2 | Biochemical Activity | 20659021 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Lrrk2 | Biochemical Activity | 17623048 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Mbp | Biochemical Activity | 17623048 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Ywhab | Affinity Capture-Western | 21390248 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Ywhaq | Affinity Capture-Western | 21390248 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Ywhae | Affinity Capture-Western | 21390248 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Ywhaz | Affinity Capture-Western | 21390248 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Ywhah | Affinity Capture-Western | 21390248 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Ywhag | Affinity Capture-Western | 21390248 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Lrrk2 | Affinity Capture-Western | 21390248 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Ctnnb1 | Affinity Capture-Western | 22899650 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Dvl3 | Affinity Capture-Western | 22899650 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Axin1 | Affinity Capture-Western | 22899650 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Gsk3b | Affinity Capture-Western | 22899650 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Hsp90aa1 | Affinity Capture-Western | 20642453 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Ywhaq | Affinity Capture-Western | 20642453 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Herc2 | Affinity Capture-Western | 26355680 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Neurl4 | Affinity Capture-Western | 26355680 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Wsb1 | Affinity Capture-Western | 27273569 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Cdk5 | Affinity Capture-Western | 26268594 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Mapt | Affinity Capture-Western | 26268594 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Cptp | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Gpbp1l1 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Wipf1 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Myh9 | Affinity Capture-Western | 25926623 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Myo1f | Affinity Capture-Western | 25926623 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Actr2 | Affinity Capture-Western | 25926623 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Arpc3 | Affinity Capture-Western | 25926623 | 10090 | 10090 | BIOGRID |
| Lrrk2 | Rac1 | Affinity Capture-Western | 25926623 | 10090 | 10090 | BIOGRID |
Annotation of Lrrk2
Expression of Lrrk2
Disease information of Lrrk2