TcoF overview
TcoF: Map2k1
GeneID: 26395
Name: Dual specificity mitogen-activated protein kinase kinase 1
Ensembl: ENSMUSG00000004936
Species: Mouse
Class: class 3
Family: Others
Disease: 1
Go-trem: 93
Pathway: --
Super Enhancer:

chr9:64216202-64216879 chr9:64202564-64203111 chr9:64201938-64250963 chr9:64194741-64232743 chr9:64202552-64207884 chr9:64182734-64225344 chr9:64219821-64220833 chr9:64206626-64208826 chr9:64207173-64208014 chr9:64214773-64227274 chr9:64207109-64207759 chr9:64202018-64203261 chr9:64216314-64216954 chr9:64207252-64208537 chr9:64194238-64248705 chr9:64183882-64243327 chr9:64220030-64220539 chr9:64202310-64202915 chr9:64202175-64203319

Enhancer:

chr9:63503570-63509700 chr9:63515720-63528000 chr9:63557680-63576920 chr9:63582420-63597020 chr9:63599170-63605270 chr9:63632080-63644920 chr9:63684450-63688620 chr9:63741780-63745800 chr9:63775190-63777720 chr9:63787750-63792780 chr9:63897700-63899900 chr9:63928980-63934090 chr9:63951680-63954950 chr9:63965100-63965420 chr9:64017820-64020620 chr9:64021240-64022630 chr9:64022800-64023000 chr9:64023100-64023230 chr9:64027220-64028300 chr9:64049620-64051980 chr9:64096700-64101010 chr9:64129450-64131150 chr9:64187430-64188090 chr9:64188260-64188350 chr9:64188580-64188790 chr9:63907770-63908410 chr9:63936860-63937260 chr9:63953100-63953390 chr9:64075540-64075850 chr9:64129450-64129970 chr9:63813210-63827000 chr9:63836300-63841350 chr9:63952130-63953970 chr9:64020020-64020620 chr9:64021240-64022390 chr9:64129450-64130160 chr9:64100510-64101010 chr9:64129450-64129860 chr9:64187920-64188090 chr9:64381580-64382480 chr9:63897880-63898180 chr9:63906120-63906490 chr9:63941900-63942480 chr9:64021240-64021450 chr9:64100720-64101010 chr9:64129450-64129930 chr9:64234560-64234910 chr9:64352780-64353070 chr9:64020340-64020620 chr9:64021240-64021650 chr9:64100360-64101010 chr9:64129450-64130020 chr9:64188010-64188090 chr9:64021240-64021750 chr9:64129450-64130050 chr9:64019160-64020620 chr9:64075460-64076070 chr9:64099330-64101010 chr9:64129450-64131000 chr9:64187680-64188090 chr9:64020100-64020620 chr9:64021240-64022210 chr9:64075410-64076260 chr9:64099520-64101010 chr9:64129450-64130870 chr9:64319330-64321710 chr9:63897700-63898360 chr9:64019940-64020620 chr9:64027220-64028200 chr9:64019740-64020620 chr9:64075520-64075960 chr9:64099820-64101010 chr9:64129450-64131040 chr9:63935850-63937690 chr9:64021240-64022180 chr9:64099920-64101010 chr9:64129450-64130440 chr9:64186460-64187280 chr9:64233630-64238960 chr9:64291880-64299060 chr9:64318270-64324740 chr9:64349430-64353830 chr9:64356610-64357320 chr9:64395980-64415440 chr9:64429530-64447590 chr9:64465210-64486040 chr9:64487940-64489600 chr9:64496190-64500870 chr9:64501080-64502770 chr9:64583730-64585390 chr9:63815060-63817650 chr9:63936510-63938140 chr9:64019950-64020620 chr9:64021240-64022260 chr9:64099510-64101010 chr9:64129450-64130360 chr9:64186790-64187280 chr9:64233630-64236860 chr9:64349500-64353830 chr9:64379140-64382620 chr9:64433440-64444830 chr9:64450080-64458100 chr9:64467180-64482640 chr9:64482950-64486040 chr9:64487940-64488530 chr9:63897700-63898260 chr9:63953040-63953590 chr9:64019620-64020620 chr9:64023320-64023390 chr9:64089680-64091090 chr9:64300480-64300990 chr9:64020140-64020620 chr9:64021240-64022220 chr9:64100770-64101010 chr9:64021240-64021440 chr9:64043280-64043560 chr9:64100930-64101010 chr9:63935980-63938120 chr9:64018360-64020620 chr9:64023520-64023890 chr9:64024020-64024740 chr9:64073440-64080630 chr9:64089260-64092520 chr9:64099740-64101010 chr9:64410350-64415030 chr9:64543280-64545110 chr9:64548780-64553530 chr9:64583240-64585390 chr9:63723550-63724620 chr9:63775190-63776940 chr9:63897700-63898950 chr9:63931790-63933560 chr9:64019880-64020620 chr9:64045510-64047950 chr9:64100590-64101010 chr9:64129450-64130760 chr9:64187060-64187280 chr9:64233630-64238030 chr9:64303090-64305700 chr9:64416240-64416780 chr9:64453140-64454170 chr9:64459490-64460530 chr9:64465220-64466230 chr9:64438250-64439570 chr9:64019530-64020620 chr9:64021240-64021850 chr9:64129450-64130740 chr9:64187900-64188090 chr9:63897990-63898660 chr9:64031750-64033040 chr9:64046840-64047840 chr9:64018050-64020620 chr9:64030940-64033530 chr9:64044820-64050930 chr9:63897700-63898640 chr9:64019190-64020620 chr9:64100050-64101010 chr9:64129450-64130230 chr9:64186950-64187280 chr9:64187640-64188090 chr9:64452210-64455110 chr9:64019600-64020620 chr9:64129450-64130820 chr9:63824900-63830280 chr9:63897700-63898600 chr9:63905520-63908540 chr9:63932330-63933400 chr9:64019980-64020620 chr9:64021240-64022160 chr9:64100280-64101010 chr9:64129450-64130550 chr9:64187780-64188090 chr9:63827640-63829250 chr9:64019990-64020620 chr9:64100780-64101010 chr9:64129450-64130200 chr9:63775190-63777410 chr9:63897700-63899810 chr9:63931280-63933530 chr9:64017970-64020620 chr9:64097760-64101010 chr9:64129450-64132900 chr9:63888320-63889110 chr9:63897700-63899590 chr9:63905360-63910420 chr9:63928640-63928910 chr9:63931270-63933640 chr9:64018020-64020620 chr9:64099030-64101010 chr9:64129450-64132440 chr9:64187670-64188090 chr9:64299590-64301760 chr9:64376810-64385500 chr9:64411160-64417850 chr9:64432900-64442090 chr9:64100530-64101010 chr9:63809590-63814490 chr9:63814600-63819290 chr9:63821300-63829460 chr9:63905540-63909770 chr9:63928640-63929600 chr9:64020050-64020620 chr9:64187560-64188090 chr9:64021240-64021990 chr9:64099080-64101010 chr9:64129450-64130750 chr9:64187220-64187280 chr9:63897700-63899630 chr9:63906870-63910320 chr9:63936080-63938160 chr9:64020220-64020620 chr9:64021240-64022000 chr9:64088470-64089030 chr9:64099480-64101010 chr9:64129450-64130340 chr9:64187040-64187280 chr9:64129450-64129800 chr9:63897700-63898730 chr9:63905710-63906300 chr9:63907830-63908470 chr9:63914010-63915290 chr9:63932090-63933260 chr9:64020090-64020620 chr9:64021240-64021540 chr9:64100660-64101010 chr9:64129450-64129990 chr9:64233630-64235170 chr9:64294650-64295300 chr9:64376610-64377210 chr9:64453590-64454700 chr9:64100390-64101010 chr9:64187890-64188090 chr9:63775190-63777490 chr9:63815780-63827020 chr9:63897700-63899580 chr9:63970220-63974500 chr9:64017640-64020620 chr9:64030730-64033590 chr9:64041630-64052230 chr9:64062410-64077290 chr9:64096650-64101010 chr9:64129450-64135910 chr9:64187050-64187280 chr9:64233630-64239720 chr9:63897700-63899060 chr9:63971410-63972730 chr9:64047430-64048250 chr9:64081440-64083000 chr9:64100100-64101010 chr9:64129450-64130110 chr9:63442670-63445000 chr9:63458800-63463280 chr9:63506000-63510800 chr9:63514020-63515280 chr9:63515410-63515530 chr9:63515720-63518000 chr9:63573400-63576400 chr9:63592200-63597020 chr9:63621600-63624400 chr9:63788800-63791620 chr9:63897700-63899600 chr9:63931200-63934090 chr9:63935850-63937800 chr9:64044800-64051800 chr9:64062410-64083000 chr9:64088000-64101010 chr9:64129450-64130680 chr9:64187170-64187280 chr9:64060530-64062200 chr9:64020280-64020620 chr9:64021240-64021970 chr9:64098000-64101010 chr9:63375380-63376200 chr9:63382740-63383330 chr9:63442950-63444080 chr9:63515720-63517900 chr9:63555330-63556800 chr9:63596700-63597020 chr9:63604300-63605270 chr9:63619710-63620620 chr9:63627410-63631120 chr9:63632950-63636790 chr9:63743110-63745120 chr9:63775190-63777060 chr9:63789110-63790880 chr9:63812680-63814290 chr9:63819500-63829450 chr9:63897700-63898930 chr9:63905380-63908950 chr9:63914190-63916400 chr9:64019970-64020620 chr9:64021240-64021820 chr9:64088190-64089050 chr9:64100470-64101010 chr9:64129450-64130010 chr9:64187010-64187280 chr9:64233630-64235140 chr9:64256120-64257940 chr9:64302890-64304980 chr9:64305220-64306790 chr9:64308700-64309980 chr9:64320680-64324550 chr9:64352360-64353160 chr9:64415370-64417560 chr9:64422870-64425300 chr9:64486280-64486720 chr9:64511350-64512770 chr9:64584750-64585390 chr9:64791840-64792510 chr9:63520470-63522050 chr9:63650000-63652210 chr9:63743040-63745480 chr9:63775190-63776410 chr9:63789100-63791300 chr9:63812550-63814490 chr9:63816310-63819100 chr9:63820480-63824790 chr9:63827080-63829960 chr9:63845310-63846690 chr9:63905620-63908590 chr9:63914470-63915440 chr9:63931130-63933540 chr9:64019750-64020620 chr9:64186960-64187280 chr9:64294540-64295950 chr9:64305140-64306780 chr9:63650320-63651720 chr9:63887970-63889110 chr9:63897700-63900990 chr9:63901100-63901300 chr9:63901900-63911760 chr9:63916830-63918560 chr9:63928640-63928870 chr9:64020170-64020620 chr9:64021240-64021610 chr9:64129450-64130730 chr9:64187790-64188090 chr9:64318680-64324010 chr9:63813010-63819240 chr9:63827090-63829480 chr9:63836530-63838290 chr9:63897700-63899840 chr9:63905520-63909430 chr9:63913500-63916710 chr9:63916880-63918560 chr9:63930920-63934090 chr9:63936050-63937440 chr9:63941330-63943650 chr9:64023520-64023730 chr9:64078690-64083000 chr9:64099120-64101010 chr9:64129450-64130940 chr9:64187110-64187280 chr9:64295430-64295850 chr9:64305180-64305740 chr9:64379000-64384700 chr9:64435710-64440370 chr9:64451220-64455360 chr9:63813100-63814460 chr9:64075540-64075890 chr9:64099840-64101010 chr9:63815330-63819230 chr9:63824880-63826020 chr9:63827170-63828880 chr9:63831130-63834370 chr9:63837630-63838710 chr9:63897700-63898890 chr9:63907790-63908770 chr9:63914320-63915460 chr9:63931510-63933510 chr9:63935990-63938100 chr9:63942050-63943170 chr9:64050050-64051620 chr9:64081370-64082680 chr9:64099830-64101010 chr9:64129460-64130150 chr9:64187730-64188090 chr9:63845030-63850360 chr9:63913920-63916760 chr9:63929490-63934090 chr9:63935850-63937970 chr9:63950790-63954950 chr9:63970680-63974500 chr9:64021240-64022020 chr9:64097540-64101010 chr9:64129450-64131270 chr9:63522450-63522990 chr9:63529910-63531530 chr9:63531850-63532540 chr9:63604320-63605270 chr9:63622180-63623800 chr9:63632620-63634160 chr9:63637960-63642570 chr9:63728870-63729350 chr9:63789110-63790290 chr9:63836240-63837970 chr9:63897700-63899770 chr9:63916960-63917660 chr9:63953140-63953460 chr9:64063880-64064500 chr9:64129450-64131220 chr9:64152620-64154560 chr9:64187860-64188090 chr9:64213490-64213890 chr9:64300260-64300990 chr9:64293340-64301880 chr9:64021240-64022030 chr9:64100040-64101010 chr9:64129450-64130570 chr9:64187540-64188090 chr9:64374640-64377300 chr9:64019860-64020620 chr9:64021240-64022380 chr9:63812960-63814450 chr9:63897700-63899050 chr9:64021240-64022150 chr9:64081390-64082890 chr9:64090520-64092220 chr9:64187690-64188090 chr9:64293140-64296250 chr9:63815450-63817390 chr9:64100420-64101010 chr9:64187830-64188090 chr9:64095840-64101010 chr9:63931400-63933450 chr9:63936560-63938070 chr9:63952060-63954020 chr9:64090090-64090880 chr9:64099420-64101010 chr9:64129450-64129960 chr9:64187820-64188090 chr9:64020230-64020620 chr9:64021240-64022400 chr9:64099810-64101010 chr9:64129450-64130650 chr9:63936600-63938300 chr9:63952310-63953960 chr9:63936030-63937840 chr9:64019850-64020620 chr9:64021240-64021670 chr9:64096980-64101010 chr9:64186440-64187280 chr9:64438260-64439840 chr9:63936470-63937660 chr9:64020270-64020620 chr9:64021240-64022140 chr9:64100340-64101010 chr9:64187850-64188090 chr9:63897700-63898090 chr9:64089770-64091440 chr9:64100380-64101010 chr9:64129450-64129870 chr9:63789100-63791310 chr9:63813220-63814280 chr9:63814620-63819160 chr9:63829300-63830750 chr9:63831170-63833870 chr9:63837630-63838240 chr9:63907680-63908410 chr9:63914290-63915550 chr9:63931790-63934090 chr9:63936510-63937740 chr9:63942070-63943360 chr9:64046970-64047940 chr9:64049810-64051400 chr9:64063740-64066150 chr9:64100080-64101010 chr9:64129450-64129980 chr9:64187530-64188090 chr9:64294970-64295820 chr9:64021240-64021570 chr9:64019920-64020620 chr9:64129450-64129910 chr9:64074430-64078540 chr9:64187590-64188090 chr9:63897700-63898380 chr9:64021240-64021860 chr9:64074520-64076260 chr9:64097120-64101010 chr9:64299440-64301010 chr9:63897700-63898340 chr9:64075470-64075920 chr9:64100230-64101010 chr9:64020150-64020620 chr9:64021240-64021660 chr9:63775190-63776610 chr9:63827690-63829450 chr9:63931530-63933490 chr9:64020480-64020620 chr9:64021240-64022480 chr9:64187620-64188090 chr9:63815760-63817280 chr9:64031640-64033160 chr9:64044860-64050060 chr9:64100440-64101010 chr9:64129450-64130030 chr9:64020400-64020620 chr9:64021240-64021740 chr9:64100160-64101010 chr9:64129450-64129900 chr9:64187840-64188090 chr9:63897700-63898410 chr9:63907700-63908730 chr9:63935850-63936200 chr9:64020250-64020620 chr9:64021240-64022200 chr9:64031900-64032660 chr9:64047620-64048170

Promoter:

chr9:64251605-64255605

 ChIP-seq based regulatory details of Map2k1
Sample ID Experiment target Biosample term name Cell type Tissue type Source
 Downstream target genes of Map2k1
 Upstream regulatory details of Map2k1
 Protein-protein interaction of Map2k1
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
Map2k1 CPNE1 Reconstituted Complex 12522145 10090 9606 BIOGRID
Map2k1 CPNE4 Reconstituted Complex 12522145 10090 9606 BIOGRID
Map2k1 Myod1 Biochemical Activity 21454680 10090 10090 BIOGRID
Map2k1 Axin1 Affinity Capture-Western 12223491 10090 10090 BIOGRID
Map2k1 Mapk1 Biochemical Activity 21144847 10090 10090 BIOGRID
Map2k1 Pxn Affinity Capture-Western 14636584 10090 10090 BIOGRID
Map2k1 Mapk1 Biochemical Activity 11435472 10090 10090 BIOGRID
Map2k1 Axin1 Affinity Capture-Western 18316368 10090 10090 BIOGRID
Map2k1 Mapkbp1 Affinity Capture-Western 19385034 10090 10090 BIOGRID
Map2k1 Rps6ka2 Co-fractionation 32325033 10090 10090 BIOGRID
Map2k1 Blvra Co-fractionation 32325033 10090 10090 BIOGRID
Map2k1 Iqgap1 Co-fractionation 32325033 10090 10090 BIOGRID
Map2k1 Map2k2 Co-fractionation 32325033 10090 10090 BIOGRID
Map2k1 Mapk1 Co-fractionation 32325033 10090 10090 BIOGRID
Map2k1 Ywhae Co-fractionation 32325033 10090 10090 BIOGRID
Map2k1 Lamtor2 Co-fractionation 32325033 10090 10090 BIOGRID
Map2k1 Mapk3 Co-fractionation 32325033 10090 10090 BIOGRID
 Annotation of Map2k1
 Disease information of Map2k1