TcoF overview
| TcoF: | Top1 | |
| GeneID: | 21969 | |
| Name: | DNA topoisomerase 1 | |
| Ensembl: | ENSMUSG00000070544 | |
| Species: | Mouse | |
| Class: | NA | |
| Family: | Other_CRF | |
| Disease: | -- | |
| Go-trem: | 31 | |
| Pathway: | 2 | |
| Super Enhancer: | chr2:160603007-160603928 chr2:160627035-160627893 chr2:160618773-160627994 chr2:160666552-160668338 chr2:160612988-160622605 chr2:160700039-160701013 chr2:160652681-160656438 chr2:160620180-160629942 chr2:160652147-160684318 chr2:160602076-160604678 chr2:160700235-160700796 chr2:160540950-160541551 chr2:160589635-160590464 chr2:160619622-160622638 chr2:160525288-160526737 chr2:160699914-160700972 chr2:160652213-160658808 chr2:160655181-160658914 chr2:160712242-160716074 chr2:160621708-160622333 chr2:160603218-160603931 chr2:160589785-160590304 chr2:160715217-160719368 chr2:160619536-160622781 chr2:160699854-160700857 chr2:160620684-160623026 chr2:160525701-160530684 chr2:160544921-160545682 chr2:160618290-160627789 chr2:160602217-160604481 chr2:160657321-160658330 chr2:160619451-160623046 chr2:160699627-160701257 chr2:160657624-160668135 chr2:160602330-160604098 chr2:160699787-160702869 chr2:160711263-160712947 chr2:160613805-160632138 chr2:160652823-160662315 chr2:160699947-160702794 chr2:160551811-160552738 chr2:160619767-160629075 chr2:160621759-160628275 chr2:160603195-160603925 chr2:160619984-160622980 chr2:160582833-160583973 chr2:160620153-160621791 chr2:160580874-160584798 chr2:160609793-160610438 chr2:160619798-160629282 chr2:160602706-160604488 chr2:160666248-160667968 chr2:160577671-160578549 chr2:160656005-160658277 chr2:160581044-160581986 chr2:160597904-160598236 chr2:160619726-160622292 chr2:160618923-160622267 chr2:160602666-160603837 chr2:160657648-160667777 chr2:160700123-160700848 chr2:160601889-160603881 chr2:160619074-160620375 chr2:160651076-160667627 chr2:160619481-160622861 chr2:160690438-160700896 chr2:160619095-160620037 chr2:160635552-160668185 chr2:160602797-160603794 chr2:160702589-160708277 |
|
| Enhancer: |
chr2:160350690-160357200 chr2:160369420-160373480 chr2:160430100-160436700 chr2:160472360-160479680 chr2:160523970-160528430 chr2:160557080-160557450 chr2:160586930-160587040 chr2:160587650-160596180 chr2:160622250-160634950 chr2:160671420-160678550 chr2:160679000-160698520 chr2:160801800-160803190 chr2:160803250-160805100 chr2:160882320-160885650 chr2:160557760-160558050 chr2:160567360-160567570 chr2:160165170-160165980 chr2:160185680-160189410 chr2:160587650-160595590 chr2:160622540-160625620 chr2:160628520-160633680 chr2:160697720-160698520 chr2:160557080-160557370 chr2:160277280-160278310 chr2:160557760-160557830 chr2:160566340-160567530 chr2:160698260-160698520 chr2:160333540-160334090 chr2:160697790-160698520 chr2:160581550-160582270 chr2:160582380-160582600 chr2:160582700-160582940 chr2:160583010-160583700 chr2:160697730-160698520 chr2:160246860-160248240 chr2:160252060-160254370 chr2:160557760-160562680 chr2:160583010-160583410 chr2:160698340-160698520 chr2:160557760-160562880 chr2:160527320-160527780 chr2:160557760-160562640 chr2:160583010-160583550 chr2:160557760-160559440 chr2:160713950-160715050 chr2:160727480-160727560 chr2:160727610-160728290 chr2:160728430-160729330 chr2:160729480-160729650 chr2:160729740-160730210 chr2:160730370-160730530 chr2:160730650-160730730 chr2:160730840-160730990 chr2:160731730-160732170 chr2:160726060-160727390 chr2:160258530-160259720 chr2:160275870-160278350 chr2:160735050-160735340 chr2:160735560-160736470 chr2:160736600-160737740 chr2:160726500-160727390 chr2:160472360-160486770 chr2:160431910-160432350 chr2:160557080-160557390 chr2:160472360-160476050 chr2:160173060-160176240 chr2:160177930-160180420 chr2:160182800-160187820 chr2:160351240-160353270 chr2:160557760-160559270 chr2:160333420-160335010 chr2:160481070-160484010 chr2:160481070-160482220 chr2:160335600-160337250 chr2:160351270-160353180 chr2:160557760-160566110 chr2:160479660-160486400 chr2:160557760-160558640 chr2:160480840-160482680 chr2:160329450-160330030 chr2:160276770-160278370 chr2:160557760-160559350 chr2:160557760-160562260 chr2:160276590-160278350 chr2:160557760-160558430 chr2:160277340-160278330 chr2:160472360-160480270 chr2:160597360-160599350 chr2:160481030-160494740 chr2:160557760-160559800 chr2:160481440-160485880 chr2:160129720-160130130 chr2:160179360-160179790 chr2:160152010-160152830 chr2:160557760-160558280 chr2:160472360-160476070 chr2:160336080-160337240 chr2:160525020-160527860 chr2:160614760-160616620 chr2:160557080-160557360 chr2:160572770-160573510 chr2:160652860-160653340 chr2:160247320-160248150 chr2:160557760-160558540 chr2:160557080-160557400 chr2:160698390-160698520 chr2:160713950-160714970 chr2:160472360-160486590 chr2:160557760-160559260 chr2:160563370-160569100 chr2:160587380-160587470 chr2:160587650-160590020 chr2:160590460-160596180 chr2:160614930-160616360 chr2:160623640-160624570 chr2:160629410-160630330 chr2:160631570-160632660 chr2:160635810-160637260 chr2:160673320-160673870 chr2:160697750-160698520 chr2:160706530-160707840 chr2:160713950-160714740 chr2:160786390-160787000 chr2:160787210-160787590 chr2:160787750-160787970 chr2:160525000-160528400 chr2:160557760-160558550 chr2:160562800-160568670 chr2:160697700-160698520 chr2:160713950-160717730 chr2:160557080-160557380 chr2:160017650-160018300 chr2:160173660-160175560 chr2:160182780-160184040 chr2:160252630-160253640 chr2:160258910-160259660 chr2:160271240-160273300 chr2:160276230-160278380 chr2:160303530-160305640 chr2:160351710-160352780 chr2:160355260-160356430 chr2:160370420-160372000 chr2:160557760-160560710 chr2:160697810-160698520 chr2:160713950-160714660 chr2:160736830-160737740 chr2:160757550-160759250 chr2:160259030-160259630 chr2:160557760-160558350 chr2:160697780-160698520 chr2:160736800-160737740 chr2:160757610-160759860 chr2:160557080-160557140 chr2:160481110-160486710 chr2:160258910-160259770 chr2:160277320-160278280 chr2:160557760-160558000 chr2:160697940-160698520 chr2:160526080-160527590 chr2:160544190-160545750 chr2:160589120-160594460 chr2:160622760-160625740 chr2:160627860-160633310 chr2:160706530-160708470 chr2:160277320-160278180 chr2:160557760-160559510 chr2:160622700-160623280 chr2:160629420-160631260 chr2:160631540-160632890 chr2:160697740-160698520 chr2:160348220-160352940 chr2:160433130-160436420 chr2:160472360-160477500 chr2:160525020-160527070 chr2:160557760-160562150 chr2:160587650-160590250 chr2:160682980-160689020 chr2:160696490-160698520 chr2:160802440-160803190 chr2:160430420-160433050 chr2:160428520-160429720 chr2:160475730-160478170 chr2:160527330-160528430 chr2:160528550-160529300 chr2:160533240-160534090 chr2:160557760-160558580 chr2:160614770-160616580 chr2:160666510-160667010 chr2:160685850-160686730 chr2:160697690-160698520 chr2:160777160-160777650 chr2:160786520-160787000 chr2:160787750-160788940 chr2:160830040-160830680 chr2:160901200-160902650 chr2:160557760-160559860 chr2:160591540-160595440 chr2:160776860-160780670 chr2:160258740-160259720 chr2:160435620-160436390 chr2:160540850-160541440 chr2:160541560-160542670 chr2:160543430-160545870 chr2:160557760-160558300 chr2:160566340-160568850 chr2:160614450-160616350 chr2:160622630-160624670 chr2:160629960-160632710 chr2:160685120-160686460 chr2:160697820-160698520 chr2:160713950-160714330 chr2:160778450-160780110 chr2:160869770-160871260 chr2:160622770-160623160 chr2:160706530-160706600 chr2:160431130-160432050 chr2:160786160-160787000 chr2:160787750-160790750 chr2:160178940-160179760 chr2:160525880-160526610 chr2:160557760-160557980 chr2:160567040-160569530 chr2:160583010-160583380 chr2:160178550-160180660 chr2:160525130-160526940 chr2:160629150-160633250 chr2:160634040-160637920 chr2:160713950-160715230 chr2:160795940-160801460 chr2:160807410-160808350 chr2:160808440-160808790 chr2:160544390-160545370 chr2:160557760-160558290 chr2:160697800-160698520 chr2:160408800-160409790 chr2:160557760-160558770 chr2:160594640-160595500 chr2:160557760-160559520 chr2:160566490-160569300 chr2:160581740-160582270 chr2:160582700-160582890 chr2:160525560-160526760 chr2:160557760-160558950 chr2:160567510-160568730 chr2:160622820-160623260 chr2:160630520-160631260 chr2:160697950-160698520 chr2:160713950-160714380 chr2:160737260-160737740 chr2:160697870-160698520 chr2:160431120-160431990 chr2:160408300-160409310 chr2:160557760-160558080 chr2:160685120-160686630 chr2:160697910-160698520 chr2:160713600-160713900 chr2:160713950-160714160 chr2:160249530-160254760 chr2:160525390-160527980 chr2:160588070-160590650 chr2:160697430-160698520 chr2:160259940-160261920 chr2:160527200-160527920 chr2:160528550-160528950 chr2:160533240-160534100 chr2:160557760-160559610 chr2:160583010-160583560 chr2:160252540-160254060 chr2:160260410-160260800 chr2:160277260-160278380 chr2:160566280-160569130 chr2:160622760-160623190 chr2:160698280-160698520 chr2:160713120-160713900 chr2:160351400-160352540 chr2:160557760-160558440 chr2:160585280-160585410 chr2:160585640-160585710 chr2:160597360-160600260 chr2:160622560-160623480 chr2:160628960-160633040 chr2:160697900-160698520 chr2:160706530-160707290 chr2:160480880-160482380 chr2:160587650-160595530 chr2:160630480-160632560 chr2:160706530-160707780 chr2:160277330-160277630 chr2:160481400-160482580 |
|
| Promoter: |
chr2:160643896-160647896 |
ChIP-seq based regulatory details of Top1
| Sample ID | Experiment target | Biosample term name | Cell type | Tissue type | Source |
|---|---|---|---|---|---|
| TcoF_01_22207 | Top1 | None | MECs | Thymus | Cistrome |
| TcoF_01_22206 | Top1 | None | MECs | Thymus | Cistrome |
| TcoF_01_22205 | Top1 | None | MECs | Thymus | Cistrome |
Downstream target genes of Top1
Protein-protein interaction of Top1
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| Top1 | Dhx29 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Top1 | Ebna1bp2 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Top1 | AI314180 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Top1 | Gtf2f1 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Top1 | Lars | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Top1 | Lrrc59 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Top1 | Naa35 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Top1 | Oas3 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Top1 | Ppwd1 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Top1 | Rpl15 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Top1 | Scyl2 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Top1 | Sf3a3 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
| Top1 | St18 | Co-fractionation | 32325033 | 10090 | 10090 | BIOGRID |
Annotation of Top1
Expression of Top1
Disease information of Top1