TcoF overview
| TcoF: | AKT2 | |
| GeneID: | 80063 | |
| Name: | RAC-beta serine/threonine-protein kinase | |
| Ensembl: | ENSG00000105221 | |
| Species: | Human | |
| Class: | class 2 | |
| Family: | Others | |
| Disease: | 27 | |
| Go term: | 45 | |
| Pathway: | 101 | |
| Hallmark: | 3 | |
| Super Enhancer: |
chr19:40788664-40793329 chr19:40783420-40811836 |
|
| Enhancer: |
chr19:39897570-39898380 chr19:40131550-40132790 chr19:40364770-40366020 chr19:40420480-40421090 chr19:40421700-40423760 chr19:40432140-40432960 chr19:40477150-40478050 chr19:40487670-40488790 chr19:40503060-40503760 chr19:40512090-40513180 chr19:40519210-40519570 chr19:40528810-40531060 chr19:40569460-40571800 chr19:40587820-40589010 chr19:40595320-40596070 chr19:40596140-40596700 chr19:40702370-40703210 chr19:40718880-40718980 chr19:40719100-40719420 chr19:40720130-40720870 chr19:40722180-40723090 chr19:40723280-40723860 chr19:40831210-40832240 chr19:40847800-40849330 chr19:40929450-40931770 chr19:40961810-40963990 chr19:40993760-40995980 chr19:41029550-41031400 chr19:41054680-41055090 chr19:41055320-41056140 chr19:41075630-41076340 chr19:41076640-41077760 chr19:41082890-41083130 chr19:41083540-41084050 chr19:41111130-41111310 chr19:41111560-41111630 chr19:41111740-41112130 chr19:41112210-41112300 chr19:41112430-41113270 chr19:41115780-41116430 chr19:41118100-41118970 chr19:41119100-41119300 chr19:41119440-41119820 chr19:41175930-41178300 chr19:41190460-41192810 chr19:41206360-41208500 chr19:41208600-41209270 chr19:41260830-41263230 chr19:41263410-41265330 chr19:41284300-41285920 chr19:41312580-41313040 chr19:41313460-41313710 chr19:41352000-41352770 chr19:41354280-41354510 chr19:41373760-41375400 chr19:41398060-41399340 chr19:41430350-41430920 chr19:40434210-40436250 chr19:40548840-40551100 chr19:40713080-40715000 chr19:41352960-41354120 chr19:40698620-40699840 chr19:41083190-41083300 chr19:41083340-41083460 chr19:41119940-41120220 chr19:41128930-41129500 chr19:40958980-40959620 chr19:41113440-41114120 chr19:41115570-41115650 chr19:41129990-41130390 chr19:41250590-41251030 chr19:41305540-41306240 chr19:40966310-40968130 chr19:41084450-41086220 chr19:41114510-41115430 chr19:41116560-41117050 chr19:41120350-41122790 chr19:41349880-41350530 chr19:41354670-41355720 chr19:41413570-41415670 chr19:41348840-41349440 chr19:41351390-41351860 chr19:40363290-40363520 chr19:40503820-40504150 chr19:40313540-40315980 chr19:40559800-40562090 chr19:40747980-40748440 chr19:40748600-40749060 chr19:40753150-40754430 chr19:40755150-40756170 chr19:40771360-40772690 chr19:40776620-40779080 chr19:40787340-40787920 chr19:40788070-40788440 chr19:40746610-40747840 chr19:40779330-40781610 chr19:40761180-40762830 chr19:40762960-40764660 chr19:40893040-40893400 chr19:41211090-41211220 chr19:41211350-41212720 chr19:40947990-40948230 chr19:41125400-41126390 chr19:40449450-40450900 chr19:40361060-40362220 chr19:40366570-40367290 chr19:40398510-40399180 chr19:40513310-40513600 chr19:40553910-40554570 chr19:40578560-40578740 chr19:40744000-40744810 chr19:40744880-40745950 chr19:40982270-40983680 chr19:41018100-41018510 chr19:41036500-41037700 chr19:41059570-41060050 chr19:41084120-41084360 chr19:41126760-41128300 chr19:41129640-41129840 chr19:41186960-41187450 chr19:41313180-41313380 chr19:41448960-41450040 chr19:41570660-41571420 chr19:41188870-41190320 chr19:40980400-40981340 chr19:41065020-41065800 chr19:40730720-40732280 chr19:40741260-40741790 chr19:40832390-40834310 chr19:41269580-41270910 chr19:40894200-40894860 chr19:41150950-41153250 chr19:41251100-41251760 chr19:41155830-41158070 chr19:40293260-40294400 chr19:40749120-40749510 chr19:41370680-41371350 chr19:40504320-40505200 chr19:40652730-40654780 chr19:40805840-40807850 chr19:40807860-40809030 chr19:40847000-40847690 chr19:40904720-40906440 chr19:41117890-41117970 chr19:41227790-41228860 chr19:40909770-40911650 chr19:40318300-40318930 chr19:40319220-40320350 chr19:40392910-40394120 chr19:40412720-40413880 chr19:40478460-40478560 chr19:40590840-40591280 chr19:40721570-40721960 chr19:40730260-40730390 chr19:40868710-40869800 chr19:41114280-41114380 chr19:41117300-41117760 chr19:41240330-41242710 chr19:41508780-41509900 chr19:41528700-41529630 chr19:41551010-41553320 chr19:41679470-41680530 chr19:41699350-41700440 chr19:41700620-41700790 chr19:41725380-41726540 chr19:41726760-41727050 chr19:41732820-41735150 chr19:41735230-41736870 chr19:41755600-41756410 chr19:40676400-40677540 chr19:40914160-40914240 chr19:40996160-40997110 chr19:41014580-41015110 chr19:41131290-41131760 chr19:41451320-41452440 chr19:40836620-40837790 chr19:40907760-40909610 chr19:41229780-41230490 chr19:41230900-41231240 chr19:41314350-41314980 chr19:41318610-41319420 chr19:41090820-41092340 chr19:40478150-40478270 chr19:41307320-41307540 chr19:40828280-40829910 chr19:41135730-41137470 chr19:41179930-41180700 chr19:41381780-41382320 |
|
| Promoter: |
chr19:40736224-40791443 |
ChIP-seq based regulatory details of AKT2
| Sample ID | Experiment target | Biosample type | Biosample term name | GSM ID | Tissue type | Source |
|---|
Downstream target genes of AKT2
Upstream regulatory details of AKT2
Protein-protein interaction of AKT2
| OFFICIAL_SYMBOL_A | OFFICIAL_SYMBOL_B | EXPERIMENTAL_SYSTEM | PUBMED_ID | ORGANISM_A_ID | ORGANISM_B_ID | SOURCE |
|---|---|---|---|---|---|---|
| AKT2 | APPL1 | Two-hybrid | 10490823 | 9606 | 9606 | BIOGRID |
| AKT2 | SH3RF1 | Two-hybrid | 14504284 | 9606 | 9606 | BIOGRID |
| AKT2 | TCL1A | Two-hybrid | 10983986 | 9606 | 9606 | BIOGRID |
| AKT2 | TCL1B | Two-hybrid | 10983986 | 9606 | 9606 | BIOGRID |
| AKT2 | MTCP1 | Two-hybrid | 10983986 | 9606 | 9606 | BIOGRID |
| AKT2 | TCL1A | Affinity Capture-Western | 10983986 | 9606 | 9606 | BIOGRID |
| AKT2 | APPL1 | Affinity Capture-Western | 10490823 | 9606 | 9606 | BIOGRID |
| AKT2 | SETDB1 | Affinity Capture-Western | 17577629 | 9606 | 9606 | BIOGRID |
| AKT2 | TTC3 | Affinity Capture-Western | 20059950 | 9606 | 9606 | BIOGRID |
| AKT2 | ESR1 | Biochemical Activity | 11507039 | 9606 | 9606 | BIOGRID |
| AKT2 | SH3RF1 | Biochemical Activity | 17535800 | 9606 | 9606 | BIOGRID |
| AKT2 | VIM | Affinity Capture-Western | 20856200 | 9606 | 9606 | BIOGRID |
| AKT2 | APP | Reconstituted Complex | 21832049 | 9606 | 9606 | BIOGRID |
| AKT2 | HSP90AA1 | Affinity Capture-Western | 22939624 | 9606 | 9606 | BIOGRID |
| AKT2 | PNPLA3 | Two-hybrid | 21988832 | 9606 | 9606 | BIOGRID |
| AKT2 | SNX27 | Two-hybrid | 21988832 | 9606 | 9606 | BIOGRID |
| AKT2 | APOA1 | Two-hybrid | 21988832 | 9606 | 9606 | BIOGRID |
| AKT2 | APOB | Two-hybrid | 21988832 | 9606 | 9606 | BIOGRID |
| AKT2 | CCL14 | Two-hybrid | 21988832 | 9606 | 9606 | BIOGRID |
| AKT2 | SPRR2A | Two-hybrid | 21988832 | 9606 | 9606 | BIOGRID |
| AKT2 | SORBS2 | Two-hybrid | 21988832 | 9606 | 9606 | BIOGRID |
| AKT2 | NAMPT | Two-hybrid | 21988832 | 9606 | 9606 | BIOGRID |
| AKT2 | TMED2 | Two-hybrid | 21988832 | 9606 | 9606 | BIOGRID |
| AKT2 | POFUT1 | Two-hybrid | 21988832 | 9606 | 9606 | BIOGRID |
| AKT2 | STEAP4 | Two-hybrid | 21988832 | 9606 | 9606 | BIOGRID |
| AKT2 | POLR1B | Two-hybrid | 21988832 | 9606 | 9606 | BIOGRID |
| AKT2 | PRKCZ | Affinity Capture-Western | 18353613 | 9606 | 9606 | BIOGRID |
| AKT2 | CLIP3 | Affinity Capture-Western | 19139280 | 9606 | 9606 | BIOGRID |
| AKT2 | PLEKHO1 | Affinity Capture-Western | 17942896 | 9606 | 9606 | BIOGRID |
| AKT2 | SNAI1 | Affinity Capture-Western | 22158034 | 9606 | 9606 | BIOGRID |
| AKT2 | HIST1H3A | Biochemical Activity | 22158034 | 9606 | 9606 | BIOGRID |
| AKT2 | EIF4EBP1 | Co-fractionation | 26344197 | 9606 | 9606 | BIOGRID |
| AKT2 | GGA1 | Co-fractionation | 26344197 | 9606 | 9606 | BIOGRID |
| AKT2 | PIK3CB | Co-fractionation | 26344197 | 9606 | 9606 | BIOGRID |
| AKT2 | PIK3CD | Co-fractionation | 26344197 | 9606 | 9606 | BIOGRID |
| AKT2 | RPE | Co-fractionation | 26344197 | 9606 | 9606 | BIOGRID |
| AKT2 | UBE2O | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| AKT2 | TPM2 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| AKT2 | USP9Y | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| AKT2 | FAT3 | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| AKT2 | UBB | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| AKT2 | NSMCE4A | Affinity Capture-MS | 28514442 | 9606 | 9606 | BIOGRID |
| AKT2 | PPP2CA | Affinity Capture-Western | 27563096 | 9606 | 9606 | BIOGRID |
| AKT2 | GNB1 | Affinity Capture-Western | 26895380 | 9606 | 9606 | BIOGRID |
| AKT2 | WDR26 | Affinity Capture-Western | 26895380 | 9606 | 9606 | BIOGRID |
| AKT2 | HMGCR | Negative Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| AKT2 | CDK12 | Negative Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| AKT2 | PRKAB1 | Positive Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| AKT2 | PARP1 | Positive Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| AKT2 | GRM2 | Positive Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| AKT2 | GHSR | Positive Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| AKT2 | CDK5 | Positive Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| AKT2 | PRKDC | Positive Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| AKT2 | NTRK1 | Positive Genetic | 28319085 | 9606 | 9606 | BIOGRID |
| AKT2 | BLVRA | FRET | 27166089 | 9606 | 9606 | BIOGRID |
| AKT2 | PIP5K1C | Biochemical Activity | 26149501 | 9606 | 9606 | BIOGRID |
| AKT2 | MEOX2 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| AKT2 | SORBS3 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| AKT2 | SH3RF1 | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
| AKT2 | REL | Two-hybrid | 32296183 | 9606 | 9606 | BIOGRID |
Annotation of AKT2
TCGA cancer survival map of AKT2
Expression of AKT2
Disease information of AKT2