TcoF overview
TcoF: DYRK1B
GeneID: 2874
Name: Dual-specificity kinase
Ensembl: ENSG00000105204
Species: Human
Class: class 1
Family: Others
Disease: 4
Go term: 15
Pathway: 2
Hallmark: --
Super Enhancer:

chr19:40291180-40338160 chr19:40314028-40338528 chr19:40314312-40337955 chr19:40292710-40325740 chr19:40283296-40338181 chr19:40283381-40333852 chr19:40292812-40331159 chr19:40303728-40330994

Enhancer:

chr19:40364770-40366020 chr19:40420480-40421090 chr19:40421700-40423760 chr19:40432140-40432960 chr19:40477150-40478050 chr19:40487670-40488790 chr19:40503060-40503760 chr19:40512090-40513180 chr19:40519210-40519570 chr19:40528810-40531060 chr19:40569460-40571800 chr19:40587820-40589010 chr19:40595320-40596070 chr19:40596140-40596700 chr19:40702370-40703210 chr19:40718880-40718980 chr19:40719100-40719420 chr19:40720130-40720870 chr19:40722180-40723090 chr19:40723280-40723860 chr19:40434210-40436250 chr19:40548840-40551100 chr19:40713080-40715000 chr19:39926350-39926480 chr19:40357760-40359160 chr19:40503820-40504150 chr19:40363290-40363520 chr19:40398510-40399180 chr19:40313540-40315980 chr19:40319220-40320350 chr19:39891200-39892480 chr19:39897570-39898380 chr19:40308560-40310740 chr19:40361060-40362220 chr19:40366570-40367290 chr19:40513310-40513600 chr19:40553910-40554570 chr19:40578560-40578740 chr19:40744000-40744810 chr19:40744880-40745950 chr19:40730720-40732280 chr19:39909640-39910520 chr19:40293260-40294400 chr19:40652730-40654780 chr19:40342060-40343820 chr19:40318300-40318930 chr19:40392910-40394120 chr19:40747980-40748440 chr19:40746610-40747840 chr19:39334740-39336280 chr19:39338080-39340340 chr19:39435740-39437110 chr19:40329870-40330870 chr19:40354530-40356050 chr19:39971600-39972520 chr19:40316730-40316810 chr19:40316930-40317310 chr19:40318070-40318140 chr19:39939630-39940360

Promoter:

chr19:40315990-40324841

 ChIP-seq based regulatory details of DYRK1B
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
 Downstream target genes of DYRK1B
 Protein-protein interaction of DYRK1B
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
DYRK1B RANBP9 Reconstituted Complex 14500717 9606 9606 BIOGRID
DYRK1B RANBP9 Two-hybrid 14500717 9606 9606 BIOGRID
DYRK1B HDAC5 Biochemical Activity 15546868 9606 9606 BIOGRID
DYRK1B DCAF7 Co-localization 20940704 9606 9606 BIOGRID
DYRK1B DCAF7 Affinity Capture-Western 21777625 9606 9606 BIOGRID
DYRK1B RBL1 Affinity Capture-Western 23602568 9606 9606 BIOGRID
DYRK1B RB1 Affinity Capture-Western 23602568 9606 9606 BIOGRID
DYRK1B LZTS2 Affinity Capture-Western 23602568 9606 9606 BIOGRID
DYRK1B TROAP Affinity Capture-Western 23602568 9606 9606 BIOGRID
DYRK1B RB1 FRET 23602568 9606 9606 BIOGRID
DYRK1B RBL1 FRET 23602568 9606 9606 BIOGRID
DYRK1B LZTS2 FRET 23602568 9606 9606 BIOGRID
DYRK1B TROAP FRET 23602568 9606 9606 BIOGRID
DYRK1B CDKN2A Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B AKAP11 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B PRKAR1A Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B RBL2 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B RBL1 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B CREBBP Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B EP300 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B SKI Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B FAM117B Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B TROAP Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B DCAF7 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B GLCCI1 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B FAM53C Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B FAM117A Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B RNF169 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B LZTS2 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B RB1 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B DYNLL1 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B ABCD3 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B SIPA1L1 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B WDR6 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B ATAD3B Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B SIPA1L3 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B SIPA1L2 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B ICE1 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B KIAA0232 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B ZNF516 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B ENAH Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B LZTS3 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B PTGES3 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B DDB1 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B MSL3 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B ICE2 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B KAT8 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B FOXK1 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B ARNTL Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B CCNA2 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B EP400 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B CTBP2 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B TCEAL1 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B PRKACA Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B PPP1R3F Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B TECR Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B KPNB1 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B STUB1 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B USP11 Affinity Capture-MS 23602568 9606 9606 BIOGRID
DYRK1B ID2 Biochemical Activity 26735018 9606 9606 BIOGRID
DYRK1B DYRK1B Biochemical Activity 26735018 9606 9606 BIOGRID
DYRK1B DCAF7 Affinity Capture-Western 27307198 9606 9606 BIOGRID
DYRK1B TROAP Two-hybrid 32296183 9606 9606 BIOGRID
 Annotation of DYRK1B
 TCGA cancer survival map of DYRK1B


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Disease information of  DYRK1B