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TcoF overview
TcoF: EGLN1
GeneID: 10456
Name: Egl nine homolog 1
Ensembl: ENSG00000135766
Species: Human
Class: class 1
Family: Others
Disease: 7
Go term: 29
Pathway: 7
Hallmark: --
Super Enhancer:

chr1:231554559-231559649 chr1:231528308-231561516 chr1:231512266-231561549 chr1:231520255-231561615 chr1:231556034-231558747 chr1:231543749-231558678 chr1:231555551-231559206 chr1:231555418-231558783 chr1:231512299-231561850 chr1:231518607-231561648 chr1:231523361-231559453 chr1:231523794-231559183 chr1:231523263-231532998 chr1:231501808-231563593 chr1:231528464-231562261 chr1:231512360-231560408 chr1:231512032-231559585 chr1:231512227-231559535 chr1:231526661-231558954 chr1:231513897-231558984 chr1:231518910-231557041 chr1:231520820-231560221 chr1:231523288-231559747 chr1:231523133-231559656 chr1:231530241-231559723 chr1:231523222-231559476 chr1:231523621-231559511 chr1:231523224-231559400 chr1:231512169-231559718 chr1:231523293-231559511 chr1:231512018-231559821 chr1:231523291-231559254 chr1:231512128-231559574 chr1:231556070-231559149 chr1:231555988-231559112 chr1:231528354-231559535 chr1:231523175-231559783 chr1:231507860-231559785 chr1:231527879-231559638 chr1:231512402-231560644 chr1:231512536-231560194 chr1:231518767-231560237 chr1:231518106-231561646 chr1:231517294-231561573 chr1:231523464-231559359 chr1:231514348-231559515 chr1:231520604-231558736 chr1:231512454-231559490 chr1:231528933-231559268 chr1:231512700-231559303 chr1:231523300-231559462 chr1:231527871-231561623 chr1:231520687-231561637 chr1:231527849-231561889 chr1:231527729-231561955 chr1:231528021-231561854 chr1:231524679-231562080 chr1:231527941-231562026 chr1:231528069-231561504 chr1:231527991-231561887
Enhancer:

chr1:231336000-231337100 chr1:231337260-231339610 chr1:231664570-231665000 chr1:231603570-231605030 chr1:231595450-231597740 chr1:231306540-231308470 chr1:231555270-231556740 chr1:231566840-231569200 chr1:231523450-231524400 chr1:231525600-231526430 chr1:231526660-231527010 chr1:231543020-231544940 chr1:231545680-231546490 chr1:231693700-231694190 chr1:231765610-231767380 chr1:231770800-231772600 chr1:231776010-231776710 chr1:231938730-231940140 chr1:231997340-231998500 chr1:231665110-231667110 chr1:231762680-231764840 chr1:231943730-231945530 chr1:231591410-231591820 chr1:231195030-231196070 chr1:231328370-231329850 chr1:231520230-231521900 chr1:231571480-231572820 chr1:231583910-231584660 chr1:231590420-231591140 chr1:231690100-231691040 chr1:231884300-231885670 chr1:231406750-231408050 chr1:231359140-231359480 chr1:231409810-231410700 chr1:231677820-231678220 chr1:231149140-231150410 chr1:231151880-231153260 chr1:231550520-231551060 chr1:231913090-231915320 chr1:230957510-230958350 chr1:230960270-230962460 chr1:230962500-230964340 chr1:230982670-230983480 chr1:230983580-230984410 chr1:230996780-230997060 chr1:230997230-230997550 chr1:230998840-231001170 chr1:231001280-231001510 chr1:231001630-231003920 chr1:231012690-231013590 chr1:231014760-231015810 chr1:231016330-231017710 chr1:231019510-231020140 chr1:231032550-231033340 chr1:231035180-231037320 chr1:231045820-231046480 chr1:231070400-231071880 chr1:231074160-231075130 chr1:231120000-231121560 chr1:231122580-231123350 chr1:231188240-231190650 chr1:231229040-231229670 chr1:231277840-231279960 chr1:231283380-231284390 chr1:231408140-231409660 chr1:231413720-231415750 chr1:231541220-231541460 chr1:230997740-230998020 chr1:231013690-231014530 chr1:231030420-231030800 chr1:231210960-231212130 chr1:231830550-231830940 chr1:231831050-231831800 chr1:230904590-230904920 chr1:230990150-230990660 chr1:230991460-230991620 chr1:231706920-231708550 chr1:231778480-231780610 chr1:231869800-231870890 chr1:232038630-232039160 chr1:232057770-232058910 chr1:232058980-232060420 chr1:232060800-232061320 chr1:232061430-232061930 chr1:232122490-232123170 chr1:232062130-232063830 chr1:231494850-231495850

Promoter:

chr1:231499497-231558033

 ChIP-seq based regulatory details of EGLN1
Sample ID Experiment target Biosample type Biosample term name GSM ID Tissue type Source
 Downstream target genes of EGLN1
 Upstream regulatory details of EGLN1
 Protein-protein interaction of EGLN1
OFFICIAL_SYMBOL_A OFFICIAL_SYMBOL_B EXPERIMENTAL_SYSTEM PUBMED_ID ORGANISM_A_ID ORGANISM_B_ID SOURCE
EGLN1 ING4 Reconstituted Complex 15897452 9606 9606 BIOGRID
EGLN1 ING4 Affinity Capture-Western 17848618 9606 9606 BIOGRID
EGLN1 HIST1H3A Reconstituted Complex 19624289 9606 9606 BIOGRID
EGLN1 HIST1H3A Co-crystal Structure 19624289 9606 9606 BIOGRID
EGLN1 SIAH2 Affinity Capture-Western 16958618 9606 9606 BIOGRID
EGLN1 EGLN1 Affinity Capture-Western 16958618 9606 9606 BIOGRID
EGLN1 SPRY2 Affinity Capture-Western 22006925 9606 9606 BIOGRID
EGLN1 SRC Affinity Capture-Western 21335603 9606 9606 BIOGRID
EGLN1 SRC Reconstituted Complex 21335603 9606 9606 BIOGRID
EGLN1 HIF1A Co-crystal Structure 19604478 9606 9606 BIOGRID
EGLN1 EPAS1 Reconstituted Complex 19208626 9606 9606 BIOGRID
EGLN1 FKBP8 Protein-peptide 19546213 9606 9606 BIOGRID
EGLN1 LIMD1 Affinity Capture-Western 22286099 9606 9606 BIOGRID
EGLN1 SIAH2 Affinity Capture-Western 15210114 9606 9606 BIOGRID
EGLN1 EPAS1 Two-hybrid 19147576 9606 9606 BIOGRID
EGLN1 FKBP8 Two-hybrid 19147576 9606 9606 BIOGRID
EGLN1 MAGEA11 Two-hybrid 19147576 9606 9606 BIOGRID
EGLN1 MAGEA11 Affinity Capture-Western 19147576 9606 9606 BIOGRID
EGLN1 MAGEA9 Affinity Capture-Western 19147576 9606 9606 BIOGRID
EGLN1 KRAS Two-hybrid 21988832 9606 9606 BIOGRID
EGLN1 ZNF281 Two-hybrid 21988832 9606 9606 BIOGRID
EGLN1 PLD1 Affinity Capture-Western 25361009 9606 9606 BIOGRID
EGLN1 PLD1 Reconstituted Complex 25361009 9606 9606 BIOGRID
EGLN1 HIF1A Affinity Capture-Western 25361009 9606 9606 BIOGRID
EGLN1 PLD2 Affinity Capture-Western 26611735 9606 9606 BIOGRID
EGLN1 HIF1A Affinity Capture-Western 26611735 9606 9606 BIOGRID
EGLN1 GPLD1 Affinity Capture-Western 26680696 9606 9606 BIOGRID
EGLN1 RHOBTB3 Affinity Capture-Western 26215701 9606 9606 BIOGRID
EGLN1 VHL Affinity Capture-Western 26215701 9606 9606 BIOGRID
EGLN1 FKBP8 Two-hybrid 17353276 9606 9606 BIOGRID
EGLN1 FKBP8 Affinity Capture-Western 17353276 9606 9606 BIOGRID
EGLN1 FKBP8 Affinity Capture-MS 23413029 9606 9606 BIOGRID
EGLN1 PTGES3 Affinity Capture-MS 23413029 9606 9606 BIOGRID
EGLN1 FKBP4 Affinity Capture-MS 23413029 9606 9606 BIOGRID
EGLN1 HSP90AA1 Affinity Capture-MS 23413029 9606 9606 BIOGRID
EGLN1 HSP90AB1 Affinity Capture-MS 23413029 9606 9606 BIOGRID
EGLN1 PTGES3 Affinity Capture-Western 23413029 9606 9606 BIOGRID
EGLN1 FKBP8 Affinity Capture-Western 23413029 9606 9606 BIOGRID
EGLN1 HSP90AA1 Affinity Capture-Western 23413029 9606 9606 BIOGRID
EGLN1 HSP90AB1 Affinity Capture-Western 23413029 9606 9606 BIOGRID
EGLN1 PTGES3 Affinity Capture-Western 24711448 9606 9606 BIOGRID
EGLN1 HSP90AA1 Affinity Capture-Western 24711448 9606 9606 BIOGRID
EGLN1 HSP90AB1 Affinity Capture-Western 24711448 9606 9606 BIOGRID
EGLN1 AKT1 Affinity Capture-Western 27563096 9606 9606 BIOGRID
EGLN1 AKT2 Affinity Capture-Western 27563096 9606 9606 BIOGRID
EGLN1 HIF1A Affinity Capture-Western 27563096 9606 9606 BIOGRID
EGLN1 RUNX3 Affinity Capture-Western 23542169 9606 9606 BIOGRID
EGLN1 HIF1A Biochemical Activity 16155211 9606 9606 BIOGRID
EGLN1 FKBP8 Two-hybrid 27770548 9606 9606 BIOGRID
EGLN1 HIF1A Affinity Capture-Western 24681946 9606 9606 BIOGRID
EGLN1 HIF1A Two-hybrid 17069766 9606 9606 BIOGRID
EGLN1 HIF1A Reconstituted Complex 18063574 9606 9606 BIOGRID
EGLN1 HIF1A Affinity Capture-Western 29279301 9606 9606 BIOGRID
EGLN1 HIF1A Affinity Capture-Western 31763849 9606 9606 BIOGRID
EGLN1 FKBP8 Affinity Capture-MS 31763849 9606 9606 BIOGRID
EGLN1 EGLN3 Affinity Capture-MS 31763849 9606 9606 BIOGRID
EGLN1 FKBP5 Affinity Capture-MS 31763849 9606 9606 BIOGRID
EGLN1 HIF1A Affinity Capture-MS 31763849 9606 9606 BIOGRID
EGLN1 PTGES3 Affinity Capture-MS 31763849 9606 9606 BIOGRID
EGLN1 HSP90AB1 Affinity Capture-MS 31763849 9606 9606 BIOGRID
EGLN1 ARNT Affinity Capture-MS 31763849 9606 9606 BIOGRID
EGLN1 EPAS1 Affinity Capture-MS 31763849 9606 9606 BIOGRID
EGLN1 CUL3 Affinity Capture-MS 31763849 9606 9606 BIOGRID
EGLN1 KEAP1 Affinity Capture-Western 31763849 9606 9606 BIOGRID
EGLN1 BRD4 Affinity Capture-Western 31239290 9606 9606 BIOGRID
EGLN1 SH3KBP1 Affinity Capture-Western 31142511 9606 9606 BIOGRID
 Annotation of EGLN1
 TCGA cancer survival map of EGLN1


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.


 Expression of  EGLN1
 Disease information of  EGLN1